Free for academic non-profit institutions. Other users need a Commercial license

Aliases for IGLJ Gene

Aliases for IGLJ Gene

  • Immunoglobulin Lambda Joining Cluster 3
  • Immunoglobulin Lambda Joining Group 3
  • J Region Of Lambda Light Chains 3
  • IGLJ@ 3

External Ids for IGLJ Gene

Summaries for IGLJ Gene

Entrez Gene Summary for IGLJ Gene

  • Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains (see MIM 147100) and 2 identical light chains, either kappa (see MIM 147200) or lambda, joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. The kappa and lambda light chains have no apparent functional differences. Each Ig lambda light chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by a C region gene (IGLC1; MIM 147220), that provides signaling functions. The lambda light chain V region is encoded by 2 types of genes: V genes (see MIM 147240) and joining (J) genes. Random selection of just 1 gene of each type to assemble a V region accounts for the great diversity of V regions among Ig molecules. The lambda light chain locus on chromosome 22 contains approximately 30 functional V genes, followed by approximately 4 functional J genes. Due to polymorphism, the numbers of functional V and J genes differ among individuals (Janeway et al., 2005).[supplied by OMIM, Apr 2008]

GeneCards Summary for IGLJ Gene

IGLJ (Immunoglobulin Lambda Joining Cluster) is an Uncategorized gene. Among its related pathways are Immune response Fc epsilon RI pathway and Immune response Role of DAP12 receptors in NK cells.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGLJ Gene

Genomics for IGLJ Gene

Genomic Location for IGLJ Gene

Chromosome:
22
Orientation:
Unknown strand

Genomic View for IGLJ Gene


Cytogenetic band:
GeneLoc Logo Gene Density

No data available for Regulatory Elements and RefSeq DNA sequence for IGLJ Gene

Proteins for IGLJ Gene

Post-translational modifications for IGLJ Gene

No Post-translational modifications

No data available for DME Specific Peptides for IGLJ Gene

Domains & Families for IGLJ Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGLJ Gene

Function for IGLJ Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGLJ Gene

Localization for IGLJ Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGLJ Gene

Drugs & Compounds for IGLJ Gene

No Compound Related Data Available

Expression for IGLJ Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for IGLJ Gene

Orthologs for IGLJ Gene

No data available for Orthologs and Evolution for IGLJ Gene

Paralogs for IGLJ Gene

No data available for Paralogs for IGLJ Gene

Variants for IGLJ Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for IGLJ Gene

Disorders for IGLJ Gene

No disorders were found for IGLJ Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGLJ Gene

Publications for IGLJ Gene

No publications were found for IGLJ Gene.

Products for IGLJ Gene

Sources for IGLJ Gene

Content