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Aliases for IGLC6 Gene

Subcategory (RNA class) for IGLC6 Gene


Aliases for IGLC6 Gene

  • Immunoglobulin Lambda Constant 6 (Gene/Pseudogene) 2 3 5
  • Immunoglobulin Lambda Constant 6 (Kern+Oz- Marker) 2 3
  • Immunoglobulin Lambda Constant 6 (Kern+Oz- Marker, Gene/Pseudogene) 3
  • Immunoglobulin Lambda Constant Region 6 (Kern+ Oz- Marker) 3
  • Ig Lambda-6 Chain C Region 3
  • IGLC 3

External Ids for IGLC6 Gene

ORGUL Members for IGLC6 Gene

Previous HGNC Symbols for IGLC6 Gene

  • IGLC

Previous GeneCards Identifiers for IGLC6 Gene

  • GC22U990030
  • GC22P021586
  • GC22P021595
  • GC22P021605
  • GC22P021615
  • GC22P021625
  • GC22P021636
  • GC22P021646
  • GC22P021659
  • GC22P021672
  • GC22P023267
  • GC22P006229
  • GC22P023273
  • GC22P023279
  • GC22P023284
  • GC22P023289
  • GC22P023293
  • GC22P023308
  • GC22P023324

Summaries for IGLC6 Gene

GeneCards Summary for IGLC6 Gene

IGLC6 (Immunoglobulin Lambda Constant 6 (Gene/Pseudogene)) is a Pseudogene, and is affiliated with the lncRNA class. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and RET signaling. GO annotations related to this gene include antigen binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGLC6 Gene

Genomics for IGLC6 Gene

Genomic Location for IGLC6 Gene

22,919,535 bp from pter
22,919,858 bp from pter
324 bases
Plus strand

Genomic View for IGLC6 Gene

Genes around IGLC6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGLC6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGLC6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGLC6 Gene

No data available for Regulatory Elements for IGLC6 Gene

Proteins for IGLC6 Gene

  • Protein details for IGLC6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ig lambda-6 chain C region
    Protein Accession:

    Protein attributes for IGLC6 Gene

    106 amino acids
    Molecular mass:
    11277 Da
    Quaternary structure:
    No Data Available
    • Displays the following serological isotype: Mgc-, Ke+, and Oz-. Mgc- has Ala-6, Ser-8 and Thr-57; Ke+ has Gly-46 and Oz- has Arg-83.

neXtProt entry for IGLC6 Gene

Post-translational modifications for IGLC6 Gene

No Post-translational modifications

No data available for DME Specific Peptides for IGLC6 Gene

Domains & Families for IGLC6 Gene

Gene Families for IGLC6 Gene

Protein Domains for IGLC6 Gene

Suggested Antigen Peptide Sequences for IGLC6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 Ig-like (immunoglobulin-like) domain.
  • Contains 1 Ig-like (immunoglobulin-like) domain.
genes like me logo Genes that share domains with IGLC6: view

Function for IGLC6 Gene

Molecular function for IGLC6 Gene

GENATLAS Biochemistry:
immunoglobulin,lambda,constant segment 6 (Kern+Oz-marker)

Gene Ontology (GO) - Molecular Function for IGLC6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003823 antigen binding IBA --
GO:0004252 serine-type endopeptidase activity TAS --
GO:0034987 immunoglobulin receptor binding IBA --
genes like me logo Genes that share ontologies with IGLC6: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGLC6 Gene

Localization for IGLC6 Gene

Gene Ontology (GO) - Cellular Components for IGLC6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space IDA 23580065
GO:0005886 plasma membrane TAS --
GO:0009897 external side of plasma membrane IBA --
GO:0042571 immunoglobulin complex, circulating IBA --
genes like me logo Genes that share ontologies with IGLC6: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for IGLC6 Gene

Pathways & Interactions for IGLC6 Gene

genes like me logo Genes that share pathways with IGLC6: view

Interacting Proteins for IGLC6 Gene

Gene Ontology (GO) - Biological Process for IGLC6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
GO:0006898 receptor-mediated endocytosis TAS --
GO:0006910 phagocytosis, recognition IBA --
GO:0006911 phagocytosis, engulfment IBA --
GO:0006956 complement activation TAS --
genes like me logo Genes that share ontologies with IGLC6: view

No data available for SIGNOR curated interactions for IGLC6 Gene

Transcripts for IGLC6 Gene

mRNA/cDNA for IGLC6 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGLC6 Gene

No ASD Table

Relevant External Links for IGLC6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGLC6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IGLC6 Gene

mRNA differential expression in normal tissues according to GTEx for IGLC6 Gene

This gene is overexpressed in Spleen (x14.9), Small Intestine - Terminal Ileum (x8.4), Minor Salivary Gland (x6.7), and Colon - Transverse (x6.4).

Protein differential expression in normal tissues from HIPED for IGLC6 Gene

This gene is overexpressed in Testis (46.3) and Plasma (22.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IGLC6 Gene

Protein tissue co-expression partners for IGLC6 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of IGLC6 Gene:

genes like me logo Genes that share expression patterns with IGLC6: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGLC6 Gene

Orthologs for IGLC6 Gene

Evolution for IGLC6 Gene

Gene Tree for IGLC6 (if available)
Gene Tree for IGLC6 (if available)

No data available for Orthologs for IGLC6 Gene

Paralogs for IGLC6 Gene

No data available for Paralogs for IGLC6 Gene

Variants for IGLC6 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for IGLC6 Gene

Only the allele IGLC6*01 is functional. The other existing alleles are pseudogenes.

Relevant External Links for IGLC6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGLC6 Gene

Disorders for IGLC6 Gene

No disorders were found for IGLC6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGLC6 Gene

Publications for IGLC6 Gene

  1. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 3 4 64
  2. Human immunoglobulin C lambda 6 gene encodes the Kern+Oz-lambda chain and C lambda 4 and C lambda 5 are pseudogenes. (PMID: 3122211) Dariavach P. … Lefranc M.P. (Proc. Natl. Acad. Sci. U.S.A. 1987) 3 4 64
  3. Clustered arrangement of immunoglobulin lambda constant region genes in man. (PMID: 6273747) Hieter P.A. … Leder P. (Nature 1981) 3 4 64
  4. Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naA^ve to therapy. (PMID: 23580065) Pieragostino D. … Del Boccio P. (Mol Biosyst 2013) 3 64
  5. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S. … Sun P. (Mol. Immunol. 2002) 3 64

Products for IGLC6 Gene

Sources for IGLC6 Gene

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