Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IGLC2 Gene

protein-coding   GIFtS: 30
GCID: GC22P023243

immunoglobulin lambda constant 2 (Kern-Oz- marker)


(Previous symbol: IGLC)
 Explore 2 diseases affiliated with
IGLC2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for IGLC2    

Aliases
for IGLC2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Immunoglobulin Lambda Constant 2 (Kern-Oz- Marker)1 2
IGLC1 2

External Ids:    HGNC: 58561   Entrez Gene: 35382   Ensembl: ENSG000002116777   UniProtKB: P0CG053   

Export aliases for IGLC2 gene to outside databases

Previous GC identifers: GC22U990026 GC22P021090 GC22P021093 GC22P021096 GC22P021100 GC22P021102 GC22P021567 GC22P021296 GC22P021574 GC22P006211


Summaries
for IGLC2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Gene Wiki entry for IGLC2


Genomic Views
for IGLC2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
 Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for IGLC2
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for IGLC2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGLC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q11.2   Ensembl cytogenetic band:  22q11.22   HGNC cytogenetic band: 22q11.2

IGLC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IGLC2 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P023243:  view genomic region     (about GC identifiers)

Start:
 23,243,156 bp from pter      End:
 23,243,617 bp from pter
Size:
 462 bases      Orientation:
 plus strand

Proteins
for IGLC2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: LAC2_HUMAN, P0CG05 (See protein sequence)
Recommended Name: Ig lambda-2 chain C regions  
Size: 106 amino acids; 11294 Da
Miscellaneous: Displays the following serological isotype: Mcg-, Kern- and Oz-. The Mcg- isotype marker is
characterized by Ala-6, Ser-8 and Thr-57; the Ke- marker by Ser-46 and the Oz- marker by Arg-83
Sequence caution: Sequence=AAA59107.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAA20015.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA20026.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAA20028.1; Type=Erroneous initiation;
Note=Translation N-terminally extended; Sequence=CAA36049.1; Type=Erroneous initiation; Note=Translation N-terminally
extended; Sequence=CAB38569.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=EAW59547.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=EAW59549.1;
Type=Erroneous initiation; Note=Translation N-terminally extended;
6/10 PDB 3D structures from and Proteopedia for IGLC2 (see all 10):
1JVK (3D)        1LIL (3D)        1ZVO (3D)        2JB5 (3D)        2JB6 (3D)        3C2A (3D)    
Secondary accessions: A0M8Q4 P80423

Explore the universe of human proteins at neXtProt for IGLC2: NX_P0CG05

IGLC2 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).


ENSEMBL proteins: 
 ENSP00000374856  
Reactome Protein details: P0CG05
Human Recombinant Protein Products: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
Browse OriGene Protein Over-expression Lysates
OriGene Custom Protein Services for IGLC2 
GenScript Custom Purified and Recombinant Proteins Services for IGLC2
Novus Biologicals IGLC2 Protein
Novus Biologicals IGLC2 Lysate
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins
Browse Proteins at Uscn

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region TAS--
GO:0005886plasma membrane TAS--


IGLC2 for ontologies           About GeneDecksing



IGLC2 Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
R&D Systems Antibodies for IGLC2 (Ig Lambda C Domain)
Browse OriGene Antibodies
OriGene Custom Antibody Services for IGLC2 
GenScript Custom Superior Antibodies Services for IGLC2
Novus Biologicals IGLC2 Antibody
Search for Antibodies for IGLC2 at Abcam  
Browse Antibodies at Uscn
Search ThermoFisher Antibodies for IGLC2

Assay Products for IGLC2: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Immunoassay Development
Browse OriGene Fluorogenic Cell Assay Kits
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for IGLC2
Browse Enzo Life Sciences for kits & assays
Browse ELISAs and CLIAs at Uscn

Protein Domains /
Families
for IGLC2 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
IGLC2 for domains           About GeneDecksing

4 InterPro domains/families:
 IPR007110 Ig-like_dom
 IPR013783 Ig-like_fold
 IPR003006 Ig/MHC_CS
 IPR003597 Ig_C1-set

Graphical View of Domain Structure for InterPro Entry P0CG05

ProtoNet protein and cluster: P0CG05

UniProtKB/Swiss-Prot: LAC2_HUMAN, P0CG05
Similarity: Contains 1 Ig-like (immunoglobulin-like) domain


Function
for IGLC2 gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
Function Summary:
     Genatlas biochemistry entry for IGLC2:
immunoglobulin,lambda,constant segment 2 (Kern-Oz-marker)

miRNA
Products:    		Browse 3'-UTR reporter clones for miRNA target validation
Browse MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IGLC2
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate IGLC2
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:    		Browse for Gene Knock-down Tools from EMD Millipore
Browse OriGene 29mer shRNA kits
Browse OriGene siRNA
Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGLC2

Gene Editing
Products:		DNA2.0 Custom Protein Engineering Service for IGLC2

Clone
Products:     		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
Browse OriGene untagged/tagged cDNA clones in CMV expression vector
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for IGLC2
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGLC2
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGLC2 

Cell Line
Products:     		GenScript Custom overexpressing Cell Line Services for IGLC2
Search LifeMap BioReagents cell lines for IGLC2

In Situ Assay
Products:   
 		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for IGLC2

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003823antigen binding IEA--


IGLC2 for ontologies           About GeneDecksing



Pathways & Interactions
for IGLC2 gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways  About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1Cleavage of Alpha-1-Microglobulin
8/11 pathways (see all 11)
Cleavage of Alpha-1-Microglobulin1.00
FCGR activation0.65
Binding and Uptake of Ligands by Scavenger Receptors0.79
Initial triggering of complement0.60
Scavenging of Heme from Plasma0.79
Role of phospholipids in phagocytosis0.53
Classical antibody-mediated complement activation0.74
Complement cascade0.47
2Immune System
Immune System1.00
Innate Immune System0.46
Adaptive Immune System0.59
3Assembly of Signalosomes at the Activated BCR
Assembly of Signalosomes at the Activated BCR1.00
Phosphorylation of ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B)0.45
Antigen Activates B Cell Receptor Leading to Generation of Second Messengers0.78
4Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation1.00
Fcgamma receptor (FCGR) dependent phagocytosis0.80
Role of myosins in phagosome formation0.80
5Signaling by the B Cell Receptor (BCR)
Signaling by the B Cell Receptor (BCR)1.00

Pathway sources
See GeneCards unified pathways
Show all pathways


5/21        Reactome Pathways for IGLC2 (see all 21)
    Role of myosins in phagosome formation
FCGR activation
Cleavage of Alpha-1-Microglobulin
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts
Role of phospholipids in phagocytosis



IGLC2 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGLC2

STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

5/24 Interacting proteins for IGLC2 (ENSP000003748564) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
InteractantInteraction Details
GeneCardExternal ID(s)
IGHG1ENSP000003749904STRING: ENSP00000374990
IGHG2ENSP000003749874STRING: ENSP00000374987
IGHG4ENSP000003749854STRING: ENSP00000374985
IGKCENSP000003747774STRING: ENSP00000374777
PCSK9ENSP000003032084STRING: ENSP00000303208
About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006956complement activation TAS--
GO:0006958complement activation, classical pathway TAS--
GO:0045087innate immune response TAS--
GO:0050776regulation of immune response TAS--


IGLC2 for ontologies           About GeneDecksing



Drugs & Compounds
for IGLC2 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for IGLC2
Search CenterWatch for drugs/clinical trials and news about IGLC2 / LAC2 

Transcripts
for IGLC2 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000390323

miRNA
Products:     		Browse 3'-UTR reporter clones for miRNA target validation
Browse OriGene MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IGLC2
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate IGLC2
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:     		Browse for Gene Knock-down Tools from EMD Millipore
Browse OriGene 29mer shRNA kits
Browse OriGene siRNA
Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGLC2
Clone
Products:     		Browse OriGene untagged/tagged cDNA clones in CMV expression vector
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for IGLC2
DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGLC2
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGLC2 
Primer
Products:    		Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat IGLC2
  Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGLC2
  Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGLC2

24/97 AceView cDNA sequences (see all 97):

AF194698 CR623617 AF194669 CR592011 AY573191 AF063703 AF194679 CR593480 
CR605950 AF064507 AF194643 CR623132 L25296 L35920 AF194648 AF194645 
AJ319669 AF194783 BG757949 BC033102 AB064037 AF194744 AF194737 AY043110 

GeneLoc Exon Structure


Expression
for IGLC2 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

IGLC2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)
About this image
See IGLC2 Protein Expression from SPIRE MOPED and PaxDB    SABiosciences Custom PCR Arrays for IGLC2
Primer
Products:		Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat IGLC2
Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGLC2
Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGLC2
In Situ
Assay Products: 
 		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for IGLC2

Orthologs
for IGLC2 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
This gene was present in the common ancestor of chordates.

Orthologs for IGLC2 gene from 2/5 species (see all 5)    About this table
Organism Taxonomic
classification		 Gene Description Human
Similarity		 Orthology
Type		 Details
lizard
(Anolis carolinensis)		 Reptilia --
 --
 53(a)
 1 → many
 AAWZ02041299(1275-1595)
zebrafish
(Danio rerio)		 Actinopterygii CU570684.46
igl3v56
(see all 5)		 immunoglobulin light 3 variable 5
(see all 5)		 25(a)
21(a)
(see all 5)		 many ↔ many
many ↔ many
(see all 5)		 3(59697601-59699495)
24(39705312-39708147)


ENSEMBL Gene Tree for IGLC2 (if available)
TreeFam Gene Tree for IGLC2 (if available) 

Paralogs
for IGLC2 gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for IGLC2 gene
IGLL52  IGKC2  IGLC12  IGLL12  IGLC32  IGLC72  TRBC22  
18/36 SIMAP similar genes for IGLC2 using alignment to 1 protein entry:     LAC2_HUMAN(see all similar genes):
DKFZp667J0810    IGLC3    IgLC-rG    IGL@    IGLC6    IGLC7
C1 segment    DKFZp781M0386    IGLC1    IGLL5    IGLL1    IGKC
IGHG2    HLA-DQA1    IGHM    B2M    TRBC1    HLA DRB4

IGLC2 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for IGLC2
PGOHUM00000246520


Genomic Variants
for IGLC2 gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
SABiosciences Cancer Mutation PCR Assays
Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGLC2
DNA2.0 Custom Variant and Variant Library Synthesis for IGLC2

Disorders / Diseases
for IGLC2 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
IGLC2 for disorders           About GeneDecksing

2 diseases for IGLC2:    About MalaCards
meningioma    myeloma


Export disorders for IGLC2 gene to outside databases

Publications
for IGLC2 gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for IGLC2 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with IGLC2)		    Utopia: connect your pdf to the dynamic
world of online information

  1. One-megabase sequence analysis of the human immunoglobulin lambda gene locus. (PubMed id 9074928)1, 2 Kawasaki K....Shimizu N. (1997)
  2. Structure and expression of the human immunoglobulin lambda genes. (PubMed id 2115572)1, 2 Vasicek T.J. and Leder P. (1990)
  3. Comparative studies on the structure of the light chains of human immunoglobulins. IV. Assignment of a subsubgroup. (PubMed id 6404900)1, 2 Kametani F....Shimizu A. (1983)
  4. Clustered arrangement of immunoglobulin lambda constant region genes in man. (PubMed id 6273747)1, 2 Hieter P.A.... Leder P. (1981)
  5. Structural rule of antibodies. Primary structure of a monoclonal immunoglobulin-L-chain of the lambda type, subgroup IV (Bence-Jones- protein Kern). V. The complete amino acid sequence and its genetic interpretation. (PubMed id 5549568)1, 2 Ponstingl H.... Hilschmann N. (1971)
  6. The amino acid sequence of a lambda type Bence-Jones protein. 3. The complete amino acid sequence and the location of the disulfide bridges. (PubMed id 4909564)1, 2 Titani K.... Putnam F.W. (1970)
  7. Immunoglobulin lambda-chains. The complete amino acid sequence of a Bence-Jones protein. (PubMed id 4883841)1, 2 Milstein C.... Jarvis J.M. (1968)
  8. Inhibition of pathologic immunoglobulin-free light ch ain production by small interfering RNA molecules. (PubMed id 20637260)1 Phipps J.E....Wall J.S. (2010)
  9. Unraveling of the polymorphic C lambda 2-C lambda 3 amplification and the Ke+Oz- polymorphism in the human Ig lambda locus. (PubMed id 12077254)1 van der Burg M....van Dongen J.J. (2002)
  10. Recognition of immunoglobulins by Fcgamma receptors. (PubMed id 11955599)1 Radaev S. and Sun P. (2002)

External Searches for IGLC2 gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing IGLC2 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 3538 HGNC: 5856 AceView: IGL_ Ensembl:ENSG00000211677 euGenes: HUgn3538
ECgene: IGLC2 H-InvDB: IGLC2

Other Databases showing IGLC2 gene

(According to HUGE)
About This Section
   --

Specialized Databases showing IGLC2 gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for IGLC2 Pharmacogenomics, SNPs, Pathways
IMGT entry for IGLC2 The international ImMunoGeneTics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
IMGT/GENE-DBhttp://www.imgt.org/IMGT_GENE-DB/GENElect?query=2+IGLC2&species=Homo+sapiens

Intellectual Property
for IGLC2 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for IGLC2 gene:
Search GeneIP for patents involving IGLC2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for IGLC2 gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section

 
 EMD Millipore Custom Antibody & Bulk Services
 EMD Millipore Preclinical / Clinical Development Services
 EMD Millipore Immunoassay Services
 EMD Millipore Target Screening & Profiling Services

  
 Antibodies for IGLC2 (Ig Lambda C Domain)   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
 Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
 Browse OriGene Antibodies   Browse OriGene shRNA RFPs  
 Browse OriGene 29mer shRNA kits in GFP-retroviral vector   Browse OriGene genome-wide validated SYBR primer pairs  
 Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
 Browse OriGene siRNAs   Browse 3'-UTR reporter clones for miRNA target validation  
 Browse OriGene untagged cDNA clones in CMV expression vector   Browse OriGene Myc/DDK tagged cDNA clones in CMV expression vector  
 Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
 Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
 Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for IGLC2   OriGene Custom Protein Services for IGLC2  
 OriGene Custom Immunoassay Development  

 		 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IGLC2
 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGLC2
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGLC2
 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGLC2
 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGLC2
 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGLC2
 GenScript Custom Purified and Recombinant Proteins Services for IGLC2 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for IGLC2
 GenScript Custom Assay Services for IGLC2 GenScript Custom Superior Antibodies Services for IGLC2
 GenScript Custom overexpressing Cell Line Services for IGLC2 CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Search Regulatory tfbs for IGLC2
 Search Chromatin IP Primers for IGLC2
 Search RT2 qPCR Primer Assays in human, mouse, rat IGLC2
 Search GNC Networks for IGLC2
 SABiosciences Custom PCR Arrays for IGLC2
 Search Tocris compounds for IGLC2
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological cDNA Clones
 Antibodies/Proteins Production Services
 Rabbit Monoclonal Antibody Platform
 Bulk Purchasing
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 IGLC2 antibodies
 IGLC2 proteins
 IGLC2 lysates
 Search for Antibodies for IGLC2 at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for IGLC2
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 Browse ELISAs, CLIAs, Proteins, and Antibodies at Uscn
 Search LifeMap BioReagents cell lines for IGLC2
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for IGLC2
 Browse SwitchGear 3'UTR luciferase reporter plasmids for IGLC2
 Browse SwitchGear Promoter luciferase reporter plasmids for IGLC2
 Search ThermoFisher Antibodies for IGLC2
 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGLC2
       
GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category
VWF
(GIFTS: 73)
von Willebrand factor
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
Hot genes      Disease genes      IGLC2 gene at Home site.
hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4