IGKV6-21 Gene
protein-coding GIFtS : 15
GCID: GC02 M089742
immunoglobulin kappa variable 6-21 (non-functional) (Previous name: immunoglobulin kappa variable 6-21 )
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Aliasesfor IGKV6-21 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Immunoglobulin Kappa Variable 6-21 (Non-Functional) 1 2 A261 2 IGKV6211 2 Immunoglobulin Kappa Variable 6-211
Export aliases for IGKV6-21 gene to outside databases Previous GC identifers: GC02U990184 GC02M089344 GC02M089362 GC02M089363 GC02M089298 GC02M089240 GC02M089462 GC02M089547
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Summariesfor IGKV6-21 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Genomic Viewsfor IGKV6-21 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for IGKV6-21 Other transcription factors Search SABiosciences Chromatin IP Primers for IGKV6-21 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGKV6-21
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 2p12 Ensembl cytogenetic band: 2p11.2 HGNC cytogenetic band: 2p11.2 IGKV6-21 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 2 GeneLoc Exon Structure
GeneLoc location for GC02M089742: view genomic region
(about GC identifiers )
Start:
89,459,235 bp from pter
End:
89,459,850 bp from pter
Size:
616 bases
Orientation:
minus strand
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Proteinsfor IGKV6-21 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB: --IGKV6-21 Protein expression data from MOPED and PaxDb : About this image
ENSEMBL proteins: ENSP00000374791 Human Recombinant Protein Products: Antibody Products for IGKV6-21: Assay Products for IGKV6-21:
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Protein
Domains / Familiesfor IGKV6-21 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Functionfor IGKV6-21 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section
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Pathways & Interactionsfor IGKV6-21 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGKV6-21
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Drugs & Compoundsfor IGKV6-21 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for IGKV6-21 Search CenterWatch for drugs/clinical trials and news about IGKV6-21
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Transcriptsfor IGKV6-21 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390256 24/316 AceView cDNA sequences (see all 316 ):
S56915 BV193652 AA292250 BV193459 M26438 M26437 U07512 AF301490 AA883902 AA292499 U07515 U07460 U07543 U07531 AF408718 L37729 AW404465 AW407058 U07469 U07514 BQ082933 D84139 AA295377 AY574938 GeneLoc Exon Structure
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Expression for IGKV6-21 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section IGKV6-21 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: --
About this image See IGKV6-21 Protein Expression from SPIRE MOPED and PaxDB SABiosciences Custom PCR Arrays for IGKV6-21 Primer Products: Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat IGKV6-21 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGKV6-21 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGKV6-21
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Orthologsfor IGKV6-21 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for IGKV6-21 gene from 1/2 species (see all 2 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
zebrafish (Danio rerio)
Actinopterygii
CR391995.26
--
33(a)
1 → many
24(34453726-34454034)
ENSEMBL Gene Tree for IGKV6-21 (if available)TreeFam Gene Tree for IGKV6-21 (if available)
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Paralogsfor IGKV6-21 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for IGKV6-21 gene IGKV1D-37 2 IGKV1D-8 2 IGKV3D-11 2 IGKV1D-33 2 IGKV4-1 2 IGKV1-6 2 IGKV3-11 2 IGKV1D-12 2 IGKV2-40 2 IGKV3D-7 2 IGKV3-20 2 IGKV1-16 2 IGKV1-8 2 IGKV1-17 2 IGKV1-27 2 IGKV2D-26 2 IGKV1-39 2 IGKV1-5 2 IGKV6D-21 2 IGKV1-37 2 IGKV1D-17 2 IGKV1-33 2 IGKV2-30 2 ENSG00000228325 2 IGKV2D-30 2 IGKV1D-13 2 IGKV1D-39 2 IGKV2-28 2 IGKV1-12 2 IGKV5-2 2 IGKV3D-20 2 IGKV3-7 2 IGKV2D-28 2 IGKV1D-43 2 IGKV3D-15 2 IGKV3-15 2 IGKV1-9 2 IGKV1D-16 2 IGKV1D-42 2 IGKV2D-24 2 IGKV2-24 2 IGKV2D-29 2 IGKV6D-41 2 IGKV2D-40 2
IGKV6-21 for paralogs About GeneDecksing
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Genomic Variantsfor IGKV6-21 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor IGKV6-21 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
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Publicationsfor IGKV6-21 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed article for IGKV6-21 gene integrated from 9 sources : (articles sorted by number of sources associating them with IGKV6-21) Utopia : connect your pdf to the dynamic world of online information
The human immunoglobulin kappa locus. Characterization of the duplicated A regions. (PubMed id 1551402) 1 Lautner-Rieske A.... Zachau H.G. (1992)
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External Searches for IGKV6-21 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing IGKV6-21 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing IGKV6-21 gene
(According to HUGE )
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Specialized Databases showing IGKV6-21 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for IGKV6-21 Pharmacogenomics, SNPs, Pathways IMGT entry for IGKV6-21 The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section Patent Information for IGKV6-21 gene: Search GeneIP for patents involving IGKV6-21 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor IGKV6-21 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IGKV6-21 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGKV6-21 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGKV6-21 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGKV6-21 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGKV6-21 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGKV6-21
Search ThermoFisher Antibodies for IGKV6-21
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGKV6-21
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Expression for IGKV6-21
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Genomic Views for IGKV6-21
Intellectual Property for IGKV6-21
Orthologs for IGKV6-21
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Pathways / Interactions for IGKV6-21
Products for IGKV6-21
Proteins for IGKV6-21
Publications for IGKV6-21
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