Free for academic non-profit institutions. Other users need a Commercial license

Aliases for IGKV3-20 Gene

Aliases for IGKV3-20 Gene

  • Immunoglobulin Kappa Variable 3-20 2 3 5
  • Immunoglobulin Light Chain Variable Region 3
  • Ig Kappa Chain V-III Region HIC 3
  • Anti-FactorVIII ScFv 3
  • Anti-(ED-B) ScFV 3
  • Anti-IFN-G ScFv 3
  • Anti-TeTox ScFv 3
  • Anti-HCS ScFv 3
  • IGKV320 3
  • 13K18 3
  • A27 3

External Ids for IGKV3-20 Gene

Previous GeneCards Identifiers for IGKV3-20 Gene

  • GC02U990190
  • GC02M089327
  • GC02M089345
  • GC02M089346
  • GC02M089281
  • GC02M089443
  • GC02M089537
  • GC02M089741
  • GC02M089951
  • GC02M090126

Summaries for IGKV3-20 Gene

GeneCards Summary for IGKV3-20 Gene

IGKV3-20 (Immunoglobulin Kappa Variable 3-20) is a Protein Coding gene. Among its related pathways are Immune System and Regulation of actin dynamics for phagocytic cup formation. GO annotations related to this gene include antigen binding and immunoglobulin receptor binding. An important paralog of this gene is IGKV3D-15.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKV3-20 Gene

Genomics for IGKV3-20 Gene

Genomic Location for IGKV3-20 Gene

Chromosome:
2
Start:
89,142,574 bp from pter
End:
89,143,160 bp from pter
Size:
587 bases
Orientation:
Minus strand

Genomic View for IGKV3-20 Gene

Genes around IGKV3-20 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGKV3-20 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGKV3-20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGKV3-20 Gene

No data available for Regulatory Elements for IGKV3-20 Gene

Proteins for IGKV3-20 Gene

  • Protein details for IGKV3-20 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J1Z6
    Recommended name:
    Protein IGKV3-20
    Protein Accession:
    A0A0B4J1Z6

    Protein attributes for IGKV3-20 Gene

    Size:
    116 amino acids
    Molecular mass:
    12557 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGKV3-20 Gene

Proteomics data for IGKV3-20 Gene at MOPED

Post-translational modifications for IGKV3-20 Gene

No Post-translational modifications

Other Protein References for IGKV3-20 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGKV3-20 Gene

Domains & Families for IGKV3-20 Gene

Gene Families for IGKV3-20 Gene

Protein Domains for IGKV3-20 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGKV3-20: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGKV3-20 Gene

Function for IGKV3-20 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGKV3-20 Gene

Localization for IGKV3-20 Gene

Gene Ontology (GO) - Cellular Components for IGKV3-20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0071756 pentameric IgM immunoglobulin complex IDA 23250751
GO:0072562 blood microparticle IDA 22516433
genes like me logo Genes that share ontologies with IGKV3-20: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for IGKV3-20 Gene

Pathways & Interactions for IGKV3-20 Gene

genes like me logo Genes that share pathways with IGKV3-20: view

Interacting Proteins for IGKV3-20 Gene

Gene Ontology (GO) - Biological Process for IGKV3-20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response NAS 3127527
GO:0006956 complement activation TAS --
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS --
genes like me logo Genes that share ontologies with IGKV3-20: view

No data available for SIGNOR curated interactions for IGKV3-20 Gene

Drugs & Compounds for IGKV3-20 Gene

No Compound Related Data Available

Transcripts for IGKV3-20 Gene

mRNA/cDNA for IGKV3-20 Gene

(316) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGKV3-20 Gene

No ASD Table

Relevant External Links for IGKV3-20 Gene

GeneLoc Exon Structure for
IGKV3-20
ECgene alternative splicing isoforms for
IGKV3-20

Expression for IGKV3-20 Gene

mRNA expression in normal human tissues for IGKV3-20 Gene

mRNA differential expression in normal tissues according to GTEx for IGKV3-20 Gene

This gene is overexpressed in Spleen (x15.7), Colon - Transverse (x7.0), Small Intestine - Terminal Ileum (x4.6), and Minor Salivary Gland (x4.5).

Protein differential expression in normal tissues from HIPED for IGKV3-20 Gene

This gene is overexpressed in Serum (47.4) and Urine (9.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from for IGKV3-20 Gene



genes like me logo Genes that share expression patterns with IGKV3-20: view

Protein tissue co-expression partners for IGKV3-20 Gene

- Elite partner

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGKV3-20 Gene

Orthologs for IGKV3-20 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGKV3-20 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 36
  • 78 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 56 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
-- 36
  • 57 (a)
ManyToMany
-- 36
  • 57 (a)
ManyToMany
-- 36
  • 54 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 56 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
Species with no ortholog for IGKV3-20:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGKV3-20 Gene

ENSEMBL:
Gene Tree for IGKV3-20 (if available)
TreeFam:
Gene Tree for IGKV3-20 (if available)

Paralogs for IGKV3-20 Gene

genes like me logo Genes that share paralogs with IGKV3-20: view

Variants for IGKV3-20 Gene

Relevant External Links for IGKV3-20 Gene

HapMap Linkage Disequilibrium report
IGKV3-20

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGKV3-20 Gene

Disorders for IGKV3-20 Gene

Relevant External Links for IGKV3-20

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IGKV3-20

No disorders were found for IGKV3-20 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGKV3-20 Gene

Publications for IGKV3-20 Gene

  1. Characterization of molecules binding to the 70K N-terminal region of fibronectin by IFAST purification coupled with mass spectrometry. (PMID: 23750785) Moussavi-Harami S.F. … Beebe D.J. (J. Proteome Res. 2013) 3 67
  2. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3
  3. Defective immunoglobulin A (IgA) glycosylation and IgA deposits in patients with IgA nephropathy. (PMID: 23398317) Kolka R. … Jonsson T. (APMIS 2013) 3
  4. Human plasma-derived polymeric IgA and IgM antibodies associate with secretory component to yield biologically active secretory-like antibodies. (PMID: 23250751) Longet S. … CorthAcsy B. (J. Biol. Chem. 2013) 3
  5. Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity. (PMID: 22051533) Kostareli E. … Stamatopoulos K. (Leukemia 2012) 3

Products for IGKV3-20 Gene

Sources for IGKV3-20 Gene

Back to Top

Content