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Aliases for IGKV3-20 Gene

Aliases for IGKV3-20 Gene

  • Immunoglobulin Kappa Variable 3-20 2 3
  • Immunoglobulin Light Chain Variable Region 3
  • Ig Kappa Chain V-III Region HIC 3
  • Anti-FactorVIII ScFv 3
  • Anti-(ED-B) ScFV 3
  • Anti-IFN-G ScFv 3
  • Anti-TeTox ScFv 3
  • Anti-HCS ScFv 3
  • IGKV320 3
  • 13K18 3
  • A27 3

External Ids for IGKV3-20 Gene

Previous GeneCards Identifiers for IGKV3-20 Gene

  • GC02U990190
  • GC02M089327
  • GC02M089345
  • GC02M089346
  • GC02M089281
  • GC02M089443
  • GC02M089537
  • GC02M089741
  • GC02M089951
  • GC02M090126

Summaries for IGKV3-20 Gene

GeneCards Summary for IGKV3-20 Gene

IGKV3-20 (Immunoglobulin Kappa Variable 3-20) is a Protein Coding gene. Among its related pathways are PI3K/AKT Signaling in Cancer and Immune System. GO annotations related to this gene include antigen binding and immunoglobulin receptor binding. An important paralog of this gene is IGKV3D-15.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKV3-20 Gene

Genomics for IGKV3-20 Gene

Genomic Location for IGKV3-20 Gene

Chromosome:
2
Start:
89,142,574 bp from pter
End:
89,143,160 bp from pter
Size:
587 bases
Orientation:
Minus strand

Genomic View for IGKV3-20 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for IGKV3-20 Gene

No data available for Regulatory Elements for IGKV3-20 Gene

Proteins for IGKV3-20 Gene

  • Protein details for IGKV3-20 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J1Z6
    Recommended name:
    Protein IGKV3-20
    Protein Accession:
    A0A0B4J1Z6

    Protein attributes for IGKV3-20 Gene

    Size:
    116 amino acids
    Molecular mass:
    12557 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGKV3-20 Gene

Proteomics data for IGKV3-20 Gene at MOPED

Post-translational modifications for IGKV3-20 Gene

No Post-translational modifications

Other Protein References for IGKV3-20 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGKV3-20 Gene

Domains & Families for IGKV3-20 Gene

Gene Families for IGKV3-20 Gene

Protein Domains for IGKV3-20 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGKV3-20: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGKV3-20 Gene

Function for IGKV3-20 Gene

Gene Ontology (GO) - Molecular Function for IGKV3-20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003823 antigen binding NAS 3127527
GO:0034987 contributes_to immunoglobulin receptor binding IDA 23250751
genes like me logo Genes that share ontologies with IGKV3-20: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGKV3-20 Gene

Localization for IGKV3-20 Gene

Gene Ontology (GO) - Cellular Components for IGKV3-20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space IDA 23398317
GO:0005886 plasma membrane TAS --
GO:0070062 extracellular exosome IDA 19199708
GO:0071748 monomeric IgA immunoglobulin complex IDA 23250751
genes like me logo Genes that share ontologies with IGKV3-20: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for IGKV3-20 Gene

Pathways & Interactions for IGKV3-20 Gene

genes like me logo Genes that share pathways with IGKV3-20: view

Interacting Proteins for IGKV3-20 Gene

Gene Ontology (GO) - Biological Process for IGKV3-20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003094 glomerular filtration IMP 23398317
GO:0006898 receptor-mediated endocytosis TAS --
GO:0006955 immune response NAS 3127527
GO:0006956 complement activation TAS --
GO:0006958 complement activation, classical pathway TAS --
genes like me logo Genes that share ontologies with IGKV3-20: view

No data available for SIGNOR curated interactions for IGKV3-20 Gene

Drugs & Compounds for IGKV3-20 Gene

No Compound Related Data Available

Transcripts for IGKV3-20 Gene

mRNA/cDNA for IGKV3-20 Gene

(316) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGKV3-20 Gene

No ASD Table

Relevant External Links for IGKV3-20 Gene

GeneLoc Exon Structure for
IGKV3-20
ECgene alternative splicing isoforms for
IGKV3-20

Expression for IGKV3-20 Gene

mRNA expression in normal human tissues for IGKV3-20 Gene

mRNA differential expression in normal tissues according to GTEx for IGKV3-20 Gene

This gene is overexpressed in Spleen (x15.7), Colon - Transverse (x7.0), Small Intestine - Terminal Ileum (x4.6), and Minor Salivary Gland (x4.5).

Protein differential expression in normal tissues from HIPED for IGKV3-20 Gene

This gene is overexpressed in Serum (47.4) and Urine (9.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from for IGKV3-20 Gene



genes like me logo Genes that share expression patterns with IGKV3-20: view

Protein tissue co-expression partners for IGKV3-20 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGKV3-20 Gene

Orthologs for IGKV3-20 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGKV3-20 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 36
  • 78 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 56 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
-- 36
  • 57 (a)
ManyToMany
-- 36
  • 57 (a)
ManyToMany
-- 36
  • 54 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 56 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
Species with no ortholog for IGKV3-20:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGKV3-20 Gene

ENSEMBL:
Gene Tree for IGKV3-20 (if available)
TreeFam:
Gene Tree for IGKV3-20 (if available)

Paralogs for IGKV3-20 Gene

genes like me logo Genes that share paralogs with IGKV3-20: view

Variants for IGKV3-20 Gene

Relevant External Links for IGKV3-20 Gene

HapMap Linkage Disequilibrium report
IGKV3-20

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGKV3-20 Gene

Disorders for IGKV3-20 Gene

Relevant External Links for IGKV3-20

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IGKV3-20
genes like me logo Genes that share disorders with IGKV3-20: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGKV3-20 Gene

Publications for IGKV3-20 Gene

  1. Characterization of molecules binding to the 70K N-terminal region of fibronectin by IFAST purification coupled with mass spectrometry. (PMID: 23750785) Moussavi-Harami S.F. … Beebe D.J. (J. Proteome Res. 2013) 67
  2. Defective immunoglobulin A (IgA) glycosylation and IgA deposits in patients with IgA nephropathy. (PMID: 23398317) Kolka R. … Jonsson T. (APMIS 2013) 67
  3. Human plasma-derived polymeric IgA and IgM antibodies associate with secretory component to yield biologically active secretory-like antibodies. (PMID: 23250751) Longet S. … CorthAcsy B. (J. Biol. Chem. 2013) 67
  4. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 67
  5. Antigen receptor stereotypy across B-cell lymphoproliferations: the case of IGHV4-59/IGKV3-20 receptors with rheumatoid factor activity. (PMID: 22051533) Kostareli E. … Stamatopoulos K. (Leukemia 2012) 67

Products for IGKV3-20 Gene

Sources for IGKV3-20 Gene

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