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Aliases for IGKV3-11 Gene

Aliases for IGKV3-11 Gene

  • Immunoglobulin Kappa Variable 3-11 2 3
  • IGKV311 3
  • IGKC 4
  • L6 3

External Ids for IGKV3-11 Gene

Previous GeneCards Identifiers for IGKV3-11 Gene

  • GC02U990192
  • GC02M089211
  • GC02M089228
  • GC02M089165
  • GC02M089107
  • GC02M089328
  • GC02M089386
  • GC02M089731
  • GC02M089937
  • GC02M090119

Summaries for IGKV3-11 Gene

GeneCards Summary for IGKV3-11 Gene

IGKV3-11 (Immunoglobulin Kappa Variable 3-11) is a Protein Coding gene. An important paralog of this gene is IGKV3D-15.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKV3-11 Gene

Genomics for IGKV3-11 Gene

Genomic Location for IGKV3-11 Gene

Start:
88,857,361 bp from pter
End:
89,027,731 bp from pter
Size:
170,371 bases
Orientation:
Minus strand

Genomic View for IGKV3-11 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IGKV3-11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGKV3-11 Gene

No data available for Regulatory Elements for IGKV3-11 Gene

Proteins for IGKV3-11 Gene

  • Protein details for IGKV3-11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P01834-IGKC_HUMAN
    Recommended name:
    Ig kappa chain C region
    Protein Accession:
    P01834
    Secondary Accessions:

    Protein attributes for IGKV3-11 Gene

    Size:
    106 amino acids
    Molecular mass:
    11609 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • The EU sequence has the INV (3) allotypic marker, Ala-45 and Val-83. The ROY sequence has the INV (1,2) allotypic marker, Ala-45 and Leu-83

    Three dimensional structures from OCA and Proteopedia for IGKV3-11 Gene

  • Protein details for IGKV3-11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P04433-KV309_HUMAN
    Recommended name:
    Ig kappa chain V-III region VG
    Protein Accession:
    P04433
    Secondary Accessions:

    Protein attributes for IGKV3-11 Gene

    Size:
    115 amino acids
    Molecular mass:
    12575 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for IGKV3-11 Gene

neXtProt entry for IGKV3-11 Gene

Proteomics data for IGKV3-11 Gene at MOPED

Post-translational modifications for IGKV3-11 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for IGKV3-11 Gene

ENSEMBL proteins:
Reactome Protein details:

No data available for DME Specific Peptides for IGKV3-11 Gene

Domains for IGKV3-11 Gene

Gene Families for IGKV3-11 Gene

HGNC:
  • IGK :Immunoglobulins / IGK locus

Protein Domains for IGKV3-11 Gene

Graphical View of Domain Structure for InterPro Entry

P01834

UniProtKB/Swiss-Prot:

KV309_HUMAN :
  • P01834
Domain:
  • Contains 1 Ig-like (immunoglobulin-like) domain.
genes like me logo Genes that share domains with IGKV3-11: view

No data available for Suggested Antigen Peptide Sequences for IGKV3-11 Gene

Function for IGKV3-11 Gene

Gene Ontology (GO) - Molecular Function for IGKV3-11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003823 antigen binding --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IGKV3-11: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for IGKV3-11 Gene

Localization for IGKV3-11 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IGKV3-11 Gene COMPARTMENTS Subcellular localization image for IGKV3-11 gene
Compartment Confidence
extracellular 5
plasma membrane 4
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for IGKV3-11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region --
GO:0005615 extracellular space --
GO:0005886 plasma membrane --
GO:0070062 extracellular exosome --
GO:0072562 blood microparticle --
genes like me logo Genes that share ontologies with IGKV3-11: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for IGKV3-11 Gene

Pathways for IGKV3-11 Gene

SuperPathways for IGKV3-11 Gene

No Data Available

Interacting Proteins for IGKV3-11 Gene

Gene Ontology (GO) - Biological Process for IGKV3-11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001895 retina homeostasis --
GO:0006955 immune response --
GO:0006956 complement activation --
GO:0006958 complement activation, classical pathway --
GO:0038095 Fc-epsilon receptor signaling pathway --
genes like me logo Genes that share ontologies with IGKV3-11: view

No data available for Pathways by source for IGKV3-11 Gene

Transcripts for IGKV3-11 Gene

mRNA/cDNA for IGKV3-11 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IGKV3-11 Gene

No ASD Table

Relevant External Links for IGKV3-11 Gene

GeneLoc Exon Structure for
IGKV3-11
ECgene alternative splicing isoforms for
IGKV3-11

Expression for IGKV3-11 Gene

mRNA expression in normal human tissues for IGKV3-11 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for IGKV3-11 Gene

This gene is overexpressed in Spleen (12.9) and Colon - Transverse (6.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for IGKV3-11 Gene

genes like me logo Genes that share expressions with IGKV3-11: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for IGKV3-11 Gene

Orthologs for IGKV3-11 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGKV3-11 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 36
  • 78 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 57 (a)
ManyToMany
-- 36
  • 54 (a)
ManyToMany
-- 36
  • 58 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 58 (a)
ManyToMany
-- 36
  • 58 (a)
ManyToMany
-- 36
  • 60 (a)
ManyToMany
-- 36
  • 57 (a)
ManyToMany
-- 36
  • 60 (a)
ManyToMany
-- 36
  • 58 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
-- 36
  • 60 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
Species with no ortholog for IGKV3-11:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGKV3-11 Gene

ENSEMBL:
Gene Tree for IGKV3-11 (if available)
TreeFam:
Gene Tree for IGKV3-11 (if available)

Paralogs for IGKV3-11 Gene

genes like me logo Genes that share paralogs with IGKV3-11: view

Variants for IGKV3-11 Gene

Relevant External Links for IGKV3-11 Gene

HapMap Linkage Disequilibrium report
IGKV3-11

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for IGKV3-11 Gene

Disorders for IGKV3-11 Gene

UniProtKB/Swiss-Prot

KV309_HUMAN
  • Immunoglobulin kappa light chain deficiency (IGKCD) [MIM:614102]: A disease characterized by the complete absence of immunoglobulin kappa chains. {ECO:0000269 PubMed:3931219}. Note=The disease is caused by mutations affecting the gene represented in this entry.

No disorders were found for IGKV3-11 Gene.

Publications for IGKV3-11 Gene

  1. Immunoglobulin genes of different subgroups are interdigitated within the VK locus. (PMID: 6440122) Pech M. … Zachau H.G. (Nucleic Acids Res. 1984) 3
  2. The V kappa genes of the L regions and the repertoire of V kappa gene sequences in the human germ line. (PMID: 8223863) Huber C. … Zachau H.G. (Eur. J. Immunol. 1993) 3
  3. Molecular defects in a human immunoglobulin kappa chain deficiency. (PMID: 3931219) Stavnezer-Nordgren J. … Zegers B.J. (Science 1985) 4
  4. The amino acid sequence of a kappa type Bence-Jones protein. 3. The complete sequence and the location of the disulfide bridges. (PMID: 4893682) Titani K. … Putnam F.W. (J. Biol. Chem. 1969) 4
  5. The covalent structure of a human gamma G-immunoglobulin. X. Intrachain disulfide bonds. (PMID: 4923144) Gall W.E. … Edelman G.M. (Biochemistry 1970) 4

Products for IGKV3-11 Gene

Sources for IGKV3-11 Gene

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