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Aliases for IGKV2D-29 Gene

Aliases for IGKV2D-29 Gene

  • Immunoglobulin Kappa Variable 2D-29 2 3
  • IGKV2D29 3
  • A2a 3
  • A2c 3

External Ids for IGKV2D-29 Gene

Previous GeneCards Identifiers for IGKV2D-29 Gene

  • GC02U990160
  • GC02P089727
  • GC02P089744
  • GC02P089682
  • GC02P089623
  • GC02P089988
  • GC02P089989
  • GC02P089993
  • GC02P089995
  • GC02P089997
  • GC02P090019
  • GC02P090031
  • GC02P090065
  • GC02P089963

Summaries for IGKV2D-29 Gene

GeneCards Summary for IGKV2D-29 Gene

IGKV2D-29 (Immunoglobulin Kappa Variable 2D-29) is a Protein Coding gene. An important paralog of this gene is IGKV3D-15.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKV2D-29 Gene

Genomics for IGKV2D-29 Gene

Genomic Location for IGKV2D-29 Gene

Chromosome:
2
Start:
89,947,512 bp from pter
End:
89,948,279 bp from pter
Size:
768 bases
Orientation:
Plus strand

Genomic View for IGKV2D-29 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for IGKV2D-29 Gene

No data available for Regulatory Elements for IGKV2D-29 Gene

Proteins for IGKV2D-29 Gene

  • Protein details for IGKV2D-29 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B6S2
    Recommended name:
    Protein IGKV2D-29
    Protein Accession:
    A0A075B6S2

    Protein attributes for IGKV2D-29 Gene

    Size:
    120 amino acids
    Molecular mass:
    13143 Da
    Quaternary structure:
    No Data Available
  • Protein details for IGKV2D-29 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087X0P6
    Recommended name:
    Protein IGKV2D-29
    Protein Accession:
    A0A087X0P6

    Protein attributes for IGKV2D-29 Gene

    Size:
    102 amino acids
    Molecular mass:
    11192 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGKV2D-29 Gene

Proteomics data for IGKV2D-29 Gene at MOPED

Post-translational modifications for IGKV2D-29 Gene

No Post-translational modifications

Other Protein References for IGKV2D-29 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGKV2D-29 Gene

Domains & Families for IGKV2D-29 Gene

Gene Families for IGKV2D-29 Gene

Protein Domains for IGKV2D-29 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGKV2D-29: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGKV2D-29 Gene

Function for IGKV2D-29 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGKV2D-29 Gene

Localization for IGKV2D-29 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGKV2D-29 Gene

Pathways & Interactions for IGKV2D-29 Gene

SuperPathways for IGKV2D-29 Gene

No Data Available

Interacting Proteins for IGKV2D-29 Gene

Gene Ontology (GO) - Biological Process for IGKV2D-29 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for IGKV2D-29 Gene

Drugs & Compounds for IGKV2D-29 Gene

(10) Drugs for IGKV2D-29 Gene - From: NovoSeek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Dipyridamole Approved Pharma Inhibition, Inhibitor Adenosine transport inhibitor 75
Dopamine Approved Pharma Full agonist, Agonist 2814
Nitric Oxide Approved Pharma 540
Theophylline Approved Pharma Antagonist 55
cyclic amp Experimental Pharma 0

(8) Additional Compounds for IGKV2D-29 Gene - From: NovoSeek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
5-N-Ethylcarboxamidoadenosine
8-(3-chlorostyryl)caffeine
adenylate
CGS21680
DMPX
genes like me logo Genes that share compounds with IGKV2D-29: view

Transcripts for IGKV2D-29 Gene

mRNA/cDNA for IGKV2D-29 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IGKV2D-29 Gene

No ASD Table

Relevant External Links for IGKV2D-29 Gene

GeneLoc Exon Structure for
IGKV2D-29
ECgene alternative splicing isoforms for
IGKV2D-29

Expression for IGKV2D-29 Gene

mRNA expression in normal human tissues for IGKV2D-29 Gene

mRNA differential expression in normal tissues according to GTEx for IGKV2D-29 Gene

This gene is overexpressed in Spleen (x14.9), Colon - Transverse (x7.8), and Minor Salivary Gland (x4.1).

Protein differential expression in normal tissues from HIPED for IGKV2D-29 Gene

This gene is overexpressed in Skin (56.8) and Saliva (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from for IGKV2D-29 Gene



genes like me logo Genes that share expression patterns with IGKV2D-29: view

Protein tissue co-expression partners for IGKV2D-29 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGKV2D-29 Gene

Orthologs for IGKV2D-29 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for IGKV2D-29 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia IGKV2D-29 36
  • 95 (a)
OneToOne
Species with no ortholog for IGKV2D-29:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGKV2D-29 Gene

ENSEMBL:
Gene Tree for IGKV2D-29 (if available)
TreeFam:
Gene Tree for IGKV2D-29 (if available)

Paralogs for IGKV2D-29 Gene

genes like me logo Genes that share paralogs with IGKV2D-29: view

Variants for IGKV2D-29 Gene

Relevant External Links for IGKV2D-29 Gene

HapMap Linkage Disequilibrium report
IGKV2D-29

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGKV2D-29 Gene

Disorders for IGKV2D-29 Gene

genes like me logo Genes that share disorders with IGKV2D-29: view

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGKV2D-29 Gene

Publications for IGKV2D-29 Gene

  1. Human placental adenosine receptor expression is elevated in preeclampsia and hypoxia increases expression of the A2A receptor. (PMID: 19303140) von Versen-HAPynck F. … Powers R.W. (Placenta 2009) 23 67
  2. The P2Y12 antagonists, 2-methylthioadenosine 5'-monophosphate triethylammonium salt and cangrelor (ARC69931MX), can inhibit human platelet aggregation through a Gi-independent increase in cAMP levels. (PMID: 19346255) Srinivasan S. … Le Breton G.C. (J. Biol. Chem. 2009) 23 67
  3. Normalization of A2A and A3 adenosine receptor up-regulation in rheumatoid arthritis patients by treatment with anti-tumor necrosis factor alpha but not methotrexate. (PMID: 19790066) Varani K. … Borea P.A. (Arthritis Rheum. 2009) 23 67
  4. Adenosine and adenosine receptors: Newer therapeutic perspective. (PMID: 20442815) Manjunath S. … Sakhare P.M. (Indian J Pharmacol 2009) 23 67
  5. Blockage of A2A and A3 adenosine receptors decreases the desensitization of human GABA(A) receptors microtransplanted to Xenopus oocytes. (PMID: 19721003) Roseti C. … Eusebi F. (Proc. Natl. Acad. Sci. U.S.A. 2009) 23 67

Products for IGKV2D-29 Gene

Sources for IGKV2D-29 Gene

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