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Aliases for IGKV2D-28 Gene

Aliases for IGKV2D-28 Gene

  • Immunoglobulin Kappa Variable 2D-28 2 3
  • IGKV2D28 3
  • A3 3

External Ids for IGKV2D-28 Gene

Previous GeneCards Identifiers for IGKV2D-28 Gene

  • GC02U990161
  • GC02P089740
  • GC02P089757
  • GC02P089695
  • GC02P089636
  • GC02P089999
  • GC02P090005
  • GC02P090021
  • GC02P090033
  • GC02P090066

Summaries for IGKV2D-28 Gene

GeneCards Summary for IGKV2D-28 Gene

IGKV2D-28 (Immunoglobulin Kappa Variable 2D-28) is a Protein Coding gene. An important paralog of this gene is IGKV3D-15.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKV2D-28 Gene

Genomics for IGKV2D-28 Gene

Genomic Location for IGKV2D-28 Gene

Start:
89,959,979 bp from pter
End:
89,960,754 bp from pter
Size:
776 bases
Orientation:
Plus strand

Genomic View for IGKV2D-28 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IGKV2D-28 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGKV2D-28 Gene

No data available for Regulatory Elements for IGKV2D-28 Gene

Proteins for IGKV2D-28 Gene

  • Protein details for IGKV2D-28 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B6P5
    Recommended name:
    Protein IGKV2-28
    Protein Accession:
    A0A075B6P5
    Secondary Accessions:

    Protein attributes for IGKV2D-28 Gene

    Size:
    120 amino acids
    Molecular mass:
    12957 Da
    Quaternary structure:
    No Data Available
  • Protein details for IGKV2D-28 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087X1V9
    Recommended name:
    Protein IGKV2-28
    Protein Accession:
    A0A087X1V9
    Secondary Accessions:

    Protein attributes for IGKV2D-28 Gene

    Size:
    102 amino acids
    Molecular mass:
    11043 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGKV2D-28 Gene

Proteomics data for IGKV2D-28 Gene at MOPED

Post-translational modifications for IGKV2D-28 Gene

No Post-translational modifications

Other Protein References for IGKV2D-28 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGKV2D-28 Gene

Domains for IGKV2D-28 Gene

Gene Families for IGKV2D-28 Gene

HGNC:
  • IGK :Immunoglobulins / IGK locus

Protein Domains for IGKV2D-28 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGKV2D-28: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGKV2D-28 Gene

Function for IGKV2D-28 Gene

Gene Ontology (GO) - Molecular Function for IGKV2D-28 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IGKV2D-28: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for IGKV2D-28 Gene

Localization for IGKV2D-28 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IGKV2D-28 Gene COMPARTMENTS Subcellular localization image for IGKV2D-28 gene
Compartment Confidence
extracellular 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for IGKV2D-28 Gene

Pathways for IGKV2D-28 Gene

SuperPathways for IGKV2D-28 Gene

No Data Available

Interacting Proteins for IGKV2D-28 Gene

Gene Ontology (GO) - Biological Process for IGKV2D-28 Gene

None

No data available for Pathways by source for IGKV2D-28 Gene

Transcripts for IGKV2D-28 Gene

mRNA/cDNA for IGKV2D-28 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IGKV2D-28 Gene

No ASD Table

Relevant External Links for IGKV2D-28 Gene

GeneLoc Exon Structure for
IGKV2D-28
ECgene alternative splicing isoforms for
IGKV2D-28

Expression for IGKV2D-28 Gene

mRNA expression in normal human tissues for IGKV2D-28 Gene

mRNA differential expression in normal tissues according to GTEx for IGKV2D-28 Gene

This gene is overexpressed in Spleen (15.0), Small Intestine - Terminal Ileum (7.0), Colon - Transverse (6.3), Lung (6.2), and Whole Blood (5.2).

Integrated Proteomics: protein expression from for IGKV2D-28 Gene

genes like me logo Genes that share expressions with IGKV2D-28: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGKV2D-28 Gene

Orthologs for IGKV2D-28 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGKV2D-28 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 97 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 69 (a)
OneToMany
Species with no ortholog for IGKV2D-28:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGKV2D-28 Gene

ENSEMBL:
Gene Tree for IGKV2D-28 (if available)
TreeFam:
Gene Tree for IGKV2D-28 (if available)

Paralogs for IGKV2D-28 Gene

genes like me logo Genes that share paralogs with IGKV2D-28: view

Variants for IGKV2D-28 Gene

Relevant External Links for IGKV2D-28 Gene

HapMap Linkage Disequilibrium report
IGKV2D-28

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for IGKV2D-28 Gene

Disorders for IGKV2D-28 Gene

No disorders were found for IGKV2D-28 Gene.

No data available for UniProtKB/Swiss-Prot for IGKV2D-28 Gene

Publications for IGKV2D-28 Gene

  1. The human VK locus. Characterization of a duplicated region encoding 28 different immunoglobulin genes. (PMID: 3351922) Straubinger B. … Zachau H.G. (J. Mol. Biol. 1988) 3
  2. Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes. (PMID: 11298326) Kawasaki K. … Shimizu N. (Eur. J. Immunol. 2001) 3

Products for IGKV2D-28 Gene

Sources for IGKV2D-28 Gene

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