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Aliases for IGKV2-40 Gene

Aliases for IGKV2-40 Gene

  • Immunoglobulin Kappa Variable 2-40 2 3
  • Ig Kappa Chain V-II 3
  • IGKV240 3
  • O11a 3
  • O11 3

External Ids for IGKV2-40 Gene

Summaries for IGKV2-40 Gene

GeneCards Summary for IGKV2-40 Gene

IGKV2-40 (Immunoglobulin Kappa Variable 2-40) is a Protein Coding gene. Among its related pathways are PI-3K cascade and PI-3K cascade. GO annotations related to this gene include antigen binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKV2-40 Gene

Genomics for IGKV2-40 Gene

Genomic Location for IGKV2-40 Gene

Start:
89,330,110 bp from pter
End:
89,330,430 bp from pter
Size:
321 bases
Orientation:
Minus strand

Genomic View for IGKV2-40 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IGKV2-40 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGKV2-40 Gene

No data available for Regulatory Elements for IGKV2-40 Gene

Proteins for IGKV2-40 Gene

  • Protein details for IGKV2-40 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087WW87-A0A087WW87
    Recommended name:
    Protein IGKV2-40
    Protein Accession:
    A0A087WW87
    Secondary Accessions:

    Protein attributes for IGKV2-40 Gene

    Size:
    105 amino acids
    Molecular mass:
    11531 Da
    Quaternary structure:
    No Data Available
  • Protein details for IGKV2-40 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087X0Q4-A0A087X0Q4
    Recommended name:
    Protein IGKV2-40
    Protein Accession:
    A0A087X0Q4
    Secondary Accessions:

    Protein attributes for IGKV2-40 Gene

    Size:
    104 amino acids
    Molecular mass:
    11434 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGKV2-40 Gene

Proteomics data for IGKV2-40 Gene at MOPED

Post-translational modifications for IGKV2-40 Gene

No Post-translational modifications

Other Protein References for IGKV2-40 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGKV2-40 Gene

Domains for IGKV2-40 Gene

Gene Families for IGKV2-40 Gene

HGNC:
  • IGK :Immunoglobulins / IGK locus

Protein Domains for IGKV2-40 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGKV2-40: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGKV2-40 Gene

Function for IGKV2-40 Gene

Gene Ontology (GO) - Molecular Function for IGKV2-40 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003823 antigen binding NAS 5586923
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IGKV2-40: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for IGKV2-40 Gene

Localization for IGKV2-40 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IGKV2-40 Gene COMPARTMENTS Subcellular localization image for IGKV2-40 gene
Compartment Confidence
extracellular 5
plasma membrane 4
cytoskeleton 1
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for IGKV2-40 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005886 plasma membrane TAS --
GO:0070062 extracellular exosome IDA 23533145
GO:0072562 blood microparticle IDA 22516433
genes like me logo Genes that share ontologies with IGKV2-40: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for IGKV2-40 Gene

Pathways for IGKV2-40 Gene

genes like me logo Genes that share pathways with IGKV2-40: view

Interacting Proteins for IGKV2-40 Gene

Gene Ontology (GO) - Biological Process for IGKV2-40 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006898 receptor-mediated endocytosis TAS --
GO:0006955 immune response NAS 5586923
GO:0006956 complement activation TAS --
GO:0006958 complement activation, classical pathway TAS --
GO:0038095 Fc-epsilon receptor signaling pathway TAS --
genes like me logo Genes that share ontologies with IGKV2-40: view

Transcripts for IGKV2-40 Gene

mRNA/cDNA for IGKV2-40 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGKV2-40 Gene

No ASD Table

Relevant External Links for IGKV2-40 Gene

GeneLoc Exon Structure for
IGKV2-40
ECgene alternative splicing isoforms for
IGKV2-40

Expression for IGKV2-40 Gene

mRNA expression in normal human tissues for IGKV2-40 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for IGKV2-40 Gene

This gene is overexpressed in Spleen (12.9).

Integrated Proteomics: protein expression from for IGKV2-40 Gene

genes like me logo Genes that share expressions with IGKV2-40: view

No data available for mRNA Expression by UniProt/SwissProt for IGKV2-40 Gene

Orthologs for IGKV2-40 Gene

Evolution for IGKV2-40 Gene

ENSEMBL:
Gene Tree for IGKV2-40 (if available)
TreeFam:
Gene Tree for IGKV2-40 (if available)

No data available for Orthologs for IGKV2-40 Gene

Paralogs for IGKV2-40 Gene

No data available for Paralogs for IGKV2-40 Gene

Variants for IGKV2-40 Gene

Relevant External Links for IGKV2-40 Gene

HapMap Linkage Disequilibrium report
IGKV2-40

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for IGKV2-40 Gene

Disorders for IGKV2-40 Gene

No disorders were found for IGKV2-40 Gene.

No data available for UniProtKB/Swiss-Prot for IGKV2-40 Gene

Publications for IGKV2-40 Gene

  1. The human immunoglobulin kappa locus. Characterization of the duplicated O regions. (PMID: 1907917) Pargent W. … Zachau H.G. (Eur. J. Immunol. 1991) 3
  2. Molecular basis of antibody formation. (PMID: 4188189) Hilschmann N. (Naturwissenschaften 1969) 3
  3. The complete amino acid sequence of Bence Jones protein Cum (kappa- type). (PMID: 5586923) Hilschmann N. (Hoppe-Seyler's Z. Physiol. Chem. 1967) 3
  4. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S. … Sun P. (Mol. Immunol. 2002) 3
  5. An investigation into the human serum "interactome". (PMID: 15174051) Zhou M. … Conrads T.P. (Electrophoresis 2004) 3

Products for IGKV2-40 Gene

Sources for IGKV2-40 Gene

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