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Aliases for IGKV1D-33 Gene

Aliases for IGKV1D-33 Gene

  • Immunoglobulin Kappa Variable 1D-33 2 3
  • IGKV1D33 3
  • O8 3

External Ids for IGKV1D-33 Gene

Summaries for IGKV1D-33 Gene

GeneCards Summary for IGKV1D-33 Gene

IGKV1D-33 (Immunoglobulin Kappa Variable 1D-33) is a Protein Coding gene. Among its related pathways are PI-3K cascade and PI-3K cascade. GO annotations related to this gene include antigen binding. An important paralog of this gene is IGKV3D-15.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKV1D-33 Gene

Genomics for IGKV1D-33 Gene

Genomic Location for IGKV1D-33 Gene

Start:
89,913,982 bp from pter
End:
89,916,052 bp from pter
Size:
2,071 bases
Orientation:
Plus strand

Genomic View for IGKV1D-33 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IGKV1D-33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGKV1D-33 Gene

No data available for Regulatory Elements for IGKV1D-33 Gene

Proteins for IGKV1D-33 Gene

  • Protein details for IGKV1D-33 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087WZH9-A0A087WZH9
    Recommended name:
    Protein IGKV1-33
    Protein Accession:
    A0A087WZH9
    Secondary Accessions:

    Protein attributes for IGKV1D-33 Gene

    Size:
    108 amino acids
    Molecular mass:
    11842 Da
    Quaternary structure:
    No Data Available
  • Protein details for IGKV1D-33 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J1U0-A0A0B4J1U0
    Recommended name:
    Protein IGKV1-33
    Protein Accession:
    A0A0B4J1U0
    Secondary Accessions:

    Protein attributes for IGKV1D-33 Gene

    Size:
    117 amino acids
    Molecular mass:
    12848 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGKV1D-33 Gene

Proteomics data for IGKV1D-33 Gene at MOPED

Post-translational modifications for IGKV1D-33 Gene

No Post-translational modifications

Other Protein References for IGKV1D-33 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGKV1D-33 Gene

Domains for IGKV1D-33 Gene

Gene Families for IGKV1D-33 Gene

HGNC:
  • IGK :Immunoglobulins / IGK locus

Protein Domains for IGKV1D-33 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGKV1D-33: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGKV1D-33 Gene

Function for IGKV1D-33 Gene

Gene Ontology (GO) - Molecular Function for IGKV1D-33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003823 antigen binding NAS 5028201
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IGKV1D-33: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for IGKV1D-33 Gene

Localization for IGKV1D-33 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IGKV1D-33 Gene COMPARTMENTS Subcellular localization image for IGKV1D-33 gene
Compartment Confidence
extracellular 3
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for IGKV1D-33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005886 plasma membrane TAS --
GO:0072562 blood microparticle IDA 22516433
genes like me logo Genes that share ontologies with IGKV1D-33: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for IGKV1D-33 Gene

Pathways for IGKV1D-33 Gene

genes like me logo Genes that share pathways with IGKV1D-33: view

Interacting Proteins for IGKV1D-33 Gene

Gene Ontology (GO) - Biological Process for IGKV1D-33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006898 receptor-mediated endocytosis TAS --
GO:0006955 immune response NAS 5028201
GO:0006956 complement activation TAS --
GO:0006958 complement activation, classical pathway TAS --
GO:0038095 Fc-epsilon receptor signaling pathway TAS --
genes like me logo Genes that share ontologies with IGKV1D-33: view

Transcripts for IGKV1D-33 Gene

mRNA/cDNA for IGKV1D-33 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IGKV1D-33 Gene

No ASD Table

Relevant External Links for IGKV1D-33 Gene

GeneLoc Exon Structure for
IGKV1D-33
ECgene alternative splicing isoforms for
IGKV1D-33

Expression for IGKV1D-33 Gene

mRNA expression in normal human tissues for IGKV1D-33 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for IGKV1D-33 Gene

This gene is overexpressed in Spleen (14.2), Colon - Transverse (6.7), Minor Salivary Gland (5.8), and Small Intestine - Terminal Ileum (4.2).

Integrated Proteomics: protein expression from for IGKV1D-33 Gene

genes like me logo Genes that share expressions with IGKV1D-33: view

No data available for mRNA Expression by UniProt/SwissProt for IGKV1D-33 Gene

Orthologs for IGKV1D-33 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGKV1D-33 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 58 (a)
OneToMany
Species with no ortholog for IGKV1D-33:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGKV1D-33 Gene

ENSEMBL:
Gene Tree for IGKV1D-33 (if available)
TreeFam:
Gene Tree for IGKV1D-33 (if available)

Paralogs for IGKV1D-33 Gene

Pseudogenes.org Pseudogenes for IGKV1D-33 Gene

genes like me logo Genes that share paralogs with IGKV1D-33: view

Variants for IGKV1D-33 Gene

Relevant External Links for IGKV1D-33 Gene

HapMap Linkage Disequilibrium report
IGKV1D-33

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for IGKV1D-33 Gene

Disorders for IGKV1D-33 Gene

No disorders were found for IGKV1D-33 Gene.

No data available for UniProtKB/Swiss-Prot for IGKV1D-33 Gene

Publications for IGKV1D-33 Gene

  1. The structure determination of the variable portion of the Bence- Jones protein Au. (PMID: 1234024) Fehlhammer H. … Schramm H.J. (Biophys. Struct. Mech. 1975) 3
  2. Activation of C1r by proteolytic cleavage. (PMID: 1249422) Ziccardi R.J. … Cooper N.R. (J. Immunol. 1976) 3
  3. Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. IV. The less frequently expressed VL are heterogeneous. (PMID: 1940382) Scott M.G. … Nahm M.H. (J. Immunol. 1991) 3
  4. N segment insertion and region-directed somatic hypermutation in a kappa gene of a t(2;8) chromosomal translocation. (PMID: 3110741) Klobeck H.G. … Zachau H.G. (Nucleic Acids Res. 1987) 3
  5. Rule of antibody structure. The primary structure of a monoclonal immunoglobulin L-chain of the kappa-type, subgroup I (Bence-Jones protein Au). (PMID: 5028201) Schiechl H. … Hilschmann N. (Hoppe-Seyler's Z. Physiol. Chem. 1972) 3

Products for IGKV1D-33 Gene

Sources for IGKV1D-33 Gene

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