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Aliases for IGKV1D-33 Gene

Aliases for IGKV1D-33 Gene

  • Immunoglobulin Kappa Variable 1D-33 2 3
  • IGKV1D33 3
  • O8 3

External Ids for IGKV1D-33 Gene

Previous GeneCards Identifiers for IGKV1D-33 Gene

  • GC02U990174
  • GC02P089711
  • GC02P089712
  • GC02P089648
  • GC02P089589
  • GC02P089954
  • GC02P089962
  • GC02P090055

Summaries for IGKV1D-33 Gene

GeneCards Summary for IGKV1D-33 Gene

IGKV1D-33 (Immunoglobulin Kappa Variable 1D-33) is a Protein Coding gene. Among its related pathways are PI3K/AKT Signaling in Cancer and Immune System. GO annotations related to this gene include antigen binding. An important paralog of this gene is IGKV3D-15.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKV1D-33 Gene

Genomics for IGKV1D-33 Gene

Genomic Location for IGKV1D-33 Gene

Chromosome:
2
Start:
89,913,982 bp from pter
End:
89,916,052 bp from pter
Size:
2,071 bases
Orientation:
Plus strand

Genomic View for IGKV1D-33 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for IGKV1D-33 Gene

No data available for Regulatory Elements for IGKV1D-33 Gene

Proteins for IGKV1D-33 Gene

  • Protein details for IGKV1D-33 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087WZH9
    Recommended name:
    Protein IGKV1-33
    Protein Accession:
    A0A087WZH9

    Protein attributes for IGKV1D-33 Gene

    Size:
    108 amino acids
    Molecular mass:
    11842 Da
    Quaternary structure:
    No Data Available
  • Protein details for IGKV1D-33 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J1U0
    Recommended name:
    Protein IGKV1-33
    Protein Accession:
    A0A0B4J1U0

    Protein attributes for IGKV1D-33 Gene

    Size:
    117 amino acids
    Molecular mass:
    12848 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGKV1D-33 Gene

Proteomics data for IGKV1D-33 Gene at MOPED

Post-translational modifications for IGKV1D-33 Gene

No Post-translational modifications

Other Protein References for IGKV1D-33 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGKV1D-33 Gene

Domains & Families for IGKV1D-33 Gene

Gene Families for IGKV1D-33 Gene

Protein Domains for IGKV1D-33 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGKV1D-33: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGKV1D-33 Gene

Function for IGKV1D-33 Gene

Gene Ontology (GO) - Molecular Function for IGKV1D-33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003823 antigen binding NAS 5028201
genes like me logo Genes that share ontologies with IGKV1D-33: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGKV1D-33 Gene

Localization for IGKV1D-33 Gene

Gene Ontology (GO) - Cellular Components for IGKV1D-33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005886 plasma membrane TAS --
GO:0072562 blood microparticle IDA 22516433
genes like me logo Genes that share ontologies with IGKV1D-33: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for IGKV1D-33 Gene

Pathways & Interactions for IGKV1D-33 Gene

genes like me logo Genes that share pathways with IGKV1D-33: view

Interacting Proteins for IGKV1D-33 Gene

Gene Ontology (GO) - Biological Process for IGKV1D-33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006898 receptor-mediated endocytosis TAS --
GO:0006955 immune response NAS 5028201
GO:0006956 complement activation TAS --
GO:0006958 complement activation, classical pathway TAS --
GO:0038095 Fc-epsilon receptor signaling pathway TAS --
genes like me logo Genes that share ontologies with IGKV1D-33: view

No data available for SIGNOR curated interactions for IGKV1D-33 Gene

Drugs & Compounds for IGKV1D-33 Gene

No Compound Related Data Available

Transcripts for IGKV1D-33 Gene

mRNA/cDNA for IGKV1D-33 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IGKV1D-33 Gene

No ASD Table

Relevant External Links for IGKV1D-33 Gene

GeneLoc Exon Structure for
IGKV1D-33
ECgene alternative splicing isoforms for
IGKV1D-33

Expression for IGKV1D-33 Gene

mRNA expression in normal human tissues for IGKV1D-33 Gene

mRNA differential expression in normal tissues according to GTEx for IGKV1D-33 Gene

This gene is overexpressed in Spleen (x14.2), Colon - Transverse (x6.7), Minor Salivary Gland (x5.8), and Small Intestine - Terminal Ileum (x4.2).

Protein differential expression in normal tissues from HIPED for IGKV1D-33 Gene

This gene is overexpressed in Urine (38.4), Skin (23.9), and Serum (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from for IGKV1D-33 Gene



genes like me logo Genes that share expression patterns with IGKV1D-33: view

Protein tissue co-expression partners for IGKV1D-33 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGKV1D-33 Gene

Orthologs for IGKV1D-33 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGKV1D-33 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 58 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
OneToMany
Species with no ortholog for IGKV1D-33:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGKV1D-33 Gene

ENSEMBL:
Gene Tree for IGKV1D-33 (if available)
TreeFam:
Gene Tree for IGKV1D-33 (if available)

Paralogs for IGKV1D-33 Gene

Pseudogenes.org Pseudogenes for IGKV1D-33 Gene

genes like me logo Genes that share paralogs with IGKV1D-33: view

Variants for IGKV1D-33 Gene

Relevant External Links for IGKV1D-33 Gene

HapMap Linkage Disequilibrium report
IGKV1D-33

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGKV1D-33 Gene

Disorders for IGKV1D-33 Gene

genes like me logo Genes that share disorders with IGKV1D-33: view

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGKV1D-33 Gene

Publications for IGKV1D-33 Gene

  1. Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. (PMID: 22516433) Bastos-Amador P. … Falcon-Perez J.M. (J Proteomics 2012) 67
  2. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S. … Sun P. (Mol. Immunol. 2002) 67
  3. Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes. (PMID: 11298326) Kawasaki K. … Shimizu N. (Eur. J. Immunol. 2001) 67
  4. Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. IV. The less frequently expressed VL are heterogeneous. (PMID: 1940382) Scott M.G. … Nahm M.H. (J. Immunol. 1991) 67
  5. N segment insertion and region-directed somatic hypermutation in a kappa gene of a t(2;8) chromosomal translocation. (PMID: 3110741) Klobeck H.G. … Zachau H.G. (Nucleic Acids Res. 1987) 67

Products for IGKV1D-33 Gene

Sources for IGKV1D-33 Gene

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