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Aliases for IGKV1D-33 Gene

Aliases for IGKV1D-33 Gene

  • Immunoglobulin Kappa Variable 1D-33 2 3 5
  • IGKV1D33 3
  • O8 3

External Ids for IGKV1D-33 Gene

Previous GeneCards Identifiers for IGKV1D-33 Gene

  • GC02U990174
  • GC02P089711
  • GC02P089712
  • GC02P089648
  • GC02P089589
  • GC02P089954
  • GC02P089962
  • GC02P090055

Summaries for IGKV1D-33 Gene

GeneCards Summary for IGKV1D-33 Gene

IGKV1D-33 (Immunoglobulin Kappa Variable 1D-33) is a Protein Coding gene. Among its related pathways are Regulation of actin dynamics for phagocytic cup formation and Immune System. GO annotations related to this gene include antigen binding. An important paralog of this gene is IGKV3D-15.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKV1D-33 Gene

Genomics for IGKV1D-33 Gene

Regulatory Elements for IGKV1D-33 Gene

Enhancers for IGKV1D-33 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around IGKV1D-33 on UCSC Golden Path with GeneCards custom track

Genomic Location for IGKV1D-33 Gene

Chromosome:
2
Start:
89,913,982 bp from pter
End:
89,916,052 bp from pter
Size:
2,071 bases
Orientation:
Plus strand

Genomic View for IGKV1D-33 Gene

Genes around IGKV1D-33 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGKV1D-33 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGKV1D-33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGKV1D-33 Gene

Proteins for IGKV1D-33 Gene

  • Protein details for IGKV1D-33 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087WZH9
    Recommended name:
    Protein IGKV1-33
    Protein Accession:
    A0A087WZH9

    Protein attributes for IGKV1D-33 Gene

    Size:
    108 amino acids
    Molecular mass:
    11842 Da
    Quaternary structure:
    No Data Available
  • Protein details for IGKV1D-33 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J1U0
    Recommended name:
    Protein IGKV1-33
    Protein Accession:
    A0A0B4J1U0

    Protein attributes for IGKV1D-33 Gene

    Size:
    117 amino acids
    Molecular mass:
    12848 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGKV1D-33 Gene

Proteomics data for IGKV1D-33 Gene at MOPED

Post-translational modifications for IGKV1D-33 Gene

No Post-translational modifications

Other Protein References for IGKV1D-33 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGKV1D-33 Gene

Domains & Families for IGKV1D-33 Gene

Gene Families for IGKV1D-33 Gene

Protein Domains for IGKV1D-33 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGKV1D-33: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGKV1D-33 Gene

Function for IGKV1D-33 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGKV1D-33 Gene

Localization for IGKV1D-33 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGKV1D-33 Gene

Pathways & Interactions for IGKV1D-33 Gene

genes like me logo Genes that share pathways with IGKV1D-33: view

Interacting Proteins for IGKV1D-33 Gene

Gene Ontology (GO) - Biological Process for IGKV1D-33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response NAS 5028201
GO:0006956 complement activation TAS --
genes like me logo Genes that share ontologies with IGKV1D-33: view

No data available for SIGNOR curated interactions for IGKV1D-33 Gene

Drugs & Compounds for IGKV1D-33 Gene

No Compound Related Data Available

Transcripts for IGKV1D-33 Gene

mRNA/cDNA for IGKV1D-33 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IGKV1D-33 Gene

No ASD Table

Relevant External Links for IGKV1D-33 Gene

GeneLoc Exon Structure for
IGKV1D-33
ECgene alternative splicing isoforms for
IGKV1D-33

Expression for IGKV1D-33 Gene

mRNA expression in normal human tissues for IGKV1D-33 Gene

mRNA differential expression in normal tissues according to GTEx for IGKV1D-33 Gene

This gene is overexpressed in Spleen (x14.2), Colon - Transverse (x6.7), Minor Salivary Gland (x5.8), and Small Intestine - Terminal Ileum (x4.2).

Protein differential expression in normal tissues from HIPED for IGKV1D-33 Gene

This gene is overexpressed in Urine (38.4), Skin (23.9), and Serum (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from for IGKV1D-33 Gene



genes like me logo Genes that share expression patterns with IGKV1D-33: view

Protein tissue co-expression partners for IGKV1D-33 Gene

- Elite partner

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGKV1D-33 Gene

Orthologs for IGKV1D-33 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGKV1D-33 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 58 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
OneToMany
Species with no ortholog for IGKV1D-33:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGKV1D-33 Gene

ENSEMBL:
Gene Tree for IGKV1D-33 (if available)
TreeFam:
Gene Tree for IGKV1D-33 (if available)

Paralogs for IGKV1D-33 Gene

Pseudogenes.org Pseudogenes for IGKV1D-33 Gene

genes like me logo Genes that share paralogs with IGKV1D-33: view

Variants for IGKV1D-33 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for IGKV1D-33 Gene

Disorders for IGKV1D-33 Gene

No disorders were found for IGKV1D-33 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGKV1D-33 Gene

Publications for IGKV1D-33 Gene

  1. Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. (PMID: 22516433) Bastos-Amador P. … Falcon-Perez J.M. (J Proteomics 2012) 3 67
  2. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S. … Sun P. (Mol. Immunol. 2002) 3
  3. Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes. (PMID: 11298326) Kawasaki K. … Shimizu N. (Eur. J. Immunol. 2001) 3
  4. Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. IV. The less frequently expressed VL are heterogeneous. (PMID: 1940382) Scott M.G. … Nahm M.H. (J. Immunol. 1991) 3
  5. N segment insertion and region-directed somatic hypermutation in a kappa gene of a t(2;8) chromosomal translocation. (PMID: 3110741) Klobeck H.G. … Zachau H.G. (Nucleic Acids Res. 1987) 3

Products for IGKV1D-33 Gene

Sources for IGKV1D-33 Gene

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