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Aliases for IGKV1D-16 Gene

Aliases for IGKV1D-16 Gene

  • Immunoglobulin Kappa Variable 1D-16 2 3 5
  • Ig Kappa Chain V-I Region HK101 4
  • IGKV1D16 3
  • L15a 3
  • L15 3

External Ids for IGKV1D-16 Gene

Previous GeneCards Identifiers for IGKV1D-16 Gene

  • GC02U990179
  • GC02P089880
  • GC02P089897
  • GC02P089834
  • GC02P089776
  • GC02P090139

Summaries for IGKV1D-16 Gene

GeneCards Summary for IGKV1D-16 Gene

IGKV1D-16 (Immunoglobulin Kappa Variable 1D-16) is a Protein Coding gene. An important paralog of this gene is IGKV1-16.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKV1D-16 Gene

Genomics for IGKV1D-16 Gene

Genomic Location for IGKV1D-16 Gene

90,100,236 bp from pter
90,100,738 bp from pter
503 bases
Plus strand

Genomic View for IGKV1D-16 Gene

Genes around IGKV1D-16 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGKV1D-16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGKV1D-16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGKV1D-16 Gene

No data available for Regulatory Elements for IGKV1D-16 Gene

Proteins for IGKV1D-16 Gene

  • Protein details for IGKV1D-16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ig kappa chain V-ID region 16
    Protein Accession:
    Secondary Accessions:
    • A0A0B4J1Z3

    Protein attributes for IGKV1D-16 Gene

    117 amino acids
    Molecular mass:
    12730 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGKV1D-16 Gene

Post-translational modifications for IGKV1D-16 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for IGKV1D-16 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGKV1D-16 Gene

Domains & Families for IGKV1D-16 Gene

Gene Families for IGKV1D-16 Gene

Protein Domains for IGKV1D-16 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGKV1D-16: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGKV1D-16 Gene

Function for IGKV1D-16 Gene

Gene Ontology (GO) - Molecular Function for IGKV1D-16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004252 serine-type endopeptidase activity TAS --
genes like me logo Genes that share ontologies with IGKV1D-16: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGKV1D-16 Gene

Localization for IGKV1D-16 Gene

Gene Ontology (GO) - Cellular Components for IGKV1D-16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005886 plasma membrane TAS --
GO:0070062 extracellular exosome IDA --
genes like me logo Genes that share ontologies with IGKV1D-16: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for IGKV1D-16 Gene

Pathways & Interactions for IGKV1D-16 Gene

SuperPathways for IGKV1D-16 Gene

No Data Available

Gene Ontology (GO) - Biological Process for IGKV1D-16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
GO:0006898 receptor-mediated endocytosis TAS --
GO:0006955 immune response NAS --
GO:0006956 complement activation TAS --
GO:0006958 complement activation, classical pathway TAS --
genes like me logo Genes that share ontologies with IGKV1D-16: view

No data available for Pathways by source and SIGNOR curated interactions for IGKV1D-16 Gene

Drugs & Compounds for IGKV1D-16 Gene

No Compound Related Data Available

Transcripts for IGKV1D-16 Gene

mRNA/cDNA for IGKV1D-16 Gene

(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGKV1D-16 Gene

No ASD Table

Relevant External Links for IGKV1D-16 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGKV1D-16 Gene

mRNA expression in normal human tissues for IGKV1D-16 Gene

mRNA differential expression in normal tissues according to GTEx for IGKV1D-16 Gene

This gene is overexpressed in Spleen (x17.2), Colon - Transverse (x10.5), Whole Blood (x4.3), and Minor Salivary Gland (x4.2).

Protein differential expression in normal tissues from HIPED for IGKV1D-16 Gene

This gene is overexpressed in Urine (32.6), Skin (19.4), and Serum (16.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IGKV1D-16 Gene

Protein tissue co-expression partners for IGKV1D-16 Gene

- Elite partner
genes like me logo Genes that share expression patterns with IGKV1D-16: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGKV1D-16 Gene

Orthologs for IGKV1D-16 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGKV1D-16 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 35
  • 54 (a)
Species where no ortholog for IGKV1D-16 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGKV1D-16 Gene

Gene Tree for IGKV1D-16 (if available)
Gene Tree for IGKV1D-16 (if available)

Paralogs for IGKV1D-16 Gene Pseudogenes for IGKV1D-16 Gene

genes like me logo Genes that share paralogs with IGKV1D-16: view

Variants for IGKV1D-16 Gene

Sequence variations from dbSNP and Humsavar for IGKV1D-16 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
VAR_073376 -

Relevant External Links for IGKV1D-16 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGKV1D-16 Gene

Disorders for IGKV1D-16 Gene

No disorders were found for IGKV1D-16 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGKV1D-16 Gene

Publications for IGKV1D-16 Gene

  1. Evolution of immunoglobulin V genes: evidence indicating that recently duplicated human V kappa sequences have diverged by gene conversion. (PMID: 6402305) Bentley D.L. … Rabbitts T.H. (Cell 1983) 3 4 65
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 65
  3. Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes. (PMID: 11298326) Kawasaki K. … Shimizu N. (Eur. J. Immunol. 2001) 3 65
  4. Utilization of a receptor reserve for effective amplification of mitogenic signaling by an epidermal growth factor mutant deficient in receptor activation. (PMID: 11573249) Nandagopal K. … Niyogi S.K. (J. Cell. Biochem. 2001) 22 65
  5. Human immunoglobulin variable region genes -- DNA sequences of two V kappa genes and a pseudogene. (PMID: 6779204) Bentley D.L. … Rabbitts T.H. (Nature 1980) 4 65

Products for IGKV1D-16 Gene

Sources for IGKV1D-16 Gene

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