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Aliases for IGKJ@ Gene

Aliases for IGKJ@ Gene

  • Immunoglobulin Kappa Joining Cluster 3
  • Immunoglobulin Kappa Joining Region 3
  • Immunoglobulin Kappa Joining Group 3
  • IGKJ 3

External Ids for IGKJ@ Gene

Summaries for IGKJ@ Gene

Entrez Gene Summary for IGKJ@ Gene

  • Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains (see MIM 147100) and 2 identical light chains, either kappa or lambda (see MIM 147220), joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. The kappa and lambda light chains have no apparent functional differences. Each Ig kappa light chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by a C region gene (IGKC; MIM 147200), that provides signaling functions. The kappa light chain V region is encoded by 2 types of genes: V genes (see MIM 146980) and joining (J) genes. Random selection of just 1 gene of each type to assemble a V region accounts for the great diversity of V regions among Ig molecules. The kappa light chain locus on chromosome 2 contains approximately 40 functional V genes, followed by approximately 5 functional J genes. Due to polymorphism, the numbers of functional V and J genes differ among individuals (Janeway et al., 2005).[supplied by OMIM, Apr 2008]

GeneCards Summary for IGKJ@ Gene

IGKJ@ (Immunoglobulin Kappa Joining Cluster) is a Gene Cluster. Among its related pathways are Immune response Role of DAP12 receptors in NK cells and Immune response NFAT in immune response.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKJ@ Gene

Genomics for IGKJ@ Gene

Genomic Location for IGKJ@ Gene

Unknown strand

Genomic View for IGKJ@ Gene

Cytogenetic band:

No data available for Regulatory Elements and RefSeq DNA sequence for IGKJ@ Gene

Proteins for IGKJ@ Gene

Post-translational modifications for IGKJ@ Gene

No Post-translational modifications

No data available for DME Specific Peptides for IGKJ@ Gene

Domains for IGKJ@ Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGKJ@ Gene

Function for IGKJ@ Gene

Molecular function for IGKJ@ Gene

GENATLAS Biochemistry:
immunoglobulin,kappa joining region (six sequences)

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGKJ@ Gene

Localization for IGKJ@ Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGKJ@ Gene

Expression for IGKJ@ Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for IGKJ@ Gene

Orthologs for IGKJ@ Gene

No data available for Orthologs and Evolution for IGKJ@ Gene

Paralogs for IGKJ@ Gene

No data available for Paralogs for IGKJ@ Gene

Variants for IGKJ@ Gene

Relevant External Links for IGKJ@ Gene

Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for IGKJ@ Gene

Disorders for IGKJ@ Gene

No disorders were found for IGKJ@ Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for IGKJ@ Gene

Publications for IGKJ@ Gene

No publications were found for IGKJ@ Gene.

Products for IGKJ@ Gene

Sources for IGKJ@ Gene

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