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Aliases for IGKJ Gene

Aliases for IGKJ Gene

  • Immunoglobulin Kappa Joining Cluster 3
  • Immunoglobulin Kappa Joining Region 3
  • Immunoglobulin Kappa Joining Group 3
  • IGKJ@ 3

External Ids for IGKJ Gene

Summaries for IGKJ Gene

Entrez Gene Summary for IGKJ Gene

  • Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains (see MIM 147100) and 2 identical light chains, either kappa or lambda (see MIM 147220), joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. The kappa and lambda light chains have no apparent functional differences. Each Ig kappa light chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by a C region gene (IGKC; MIM 147200), that provides signaling functions. The kappa light chain V region is encoded by 2 types of genes: V genes (see MIM 146980) and joining (J) genes. Random selection of just 1 gene of each type to assemble a V region accounts for the great diversity of V regions among Ig molecules. The kappa light chain locus on chromosome 2 contains approximately 40 functional V genes, followed by approximately 5 functional J genes. Due to polymorphism, the numbers of functional V and J genes differ among individuals (Janeway et al., 2005).[supplied by OMIM, Apr 2008]

GeneCards Summary for IGKJ Gene

IGKJ (Immunoglobulin Kappa Joining Cluster) is an Uncategorized gene. Among its related pathways are Immune response Role of DAP12 receptors in NK cells and Development Angiotensin activation of ERK.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGKJ Gene

Genomics for IGKJ Gene

Genomic Location for IGKJ Gene

Chromosome:
2
Orientation:
Unknown strand

Genomic View for IGKJ Gene


Cytogenetic band:
GeneLoc Logo Gene Density

No data available for Regulatory Elements and RefSeq DNA sequence for IGKJ Gene

Proteins for IGKJ Gene

Post-translational modifications for IGKJ Gene

No Post-translational modifications

No data available for DME Specific Peptides for IGKJ Gene

Domains & Families for IGKJ Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGKJ Gene

Function for IGKJ Gene

Animal Model Products

  • Taconic Biosciences Mouse Models for IGKJ

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGKJ Gene

Localization for IGKJ Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGKJ Gene

Drugs & Compounds for IGKJ Gene

No Compound Related Data Available

Expression for IGKJ Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for IGKJ Gene

Orthologs for IGKJ Gene

No data available for Orthologs and Evolution for IGKJ Gene

Paralogs for IGKJ Gene

No data available for Paralogs for IGKJ Gene

Variants for IGKJ Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for IGKJ Gene

Disorders for IGKJ Gene

No disorders were found for IGKJ Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGKJ Gene

Publications for IGKJ Gene

No publications were found for IGKJ Gene.

Products for IGKJ Gene

Sources for IGKJ Gene

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