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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IGJ Gene

protein-coding   GIFtS: 50
GCID: GC04M071478

Immunoglobulin J Polypeptide, Linker Protein For Immunoglobulin...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Immunoglobulin J Polypeptide, Linker Protein For Immunoglobulin Alpha
And Mu Polypeptides1 2
IgJ Chain1 2
Immunoglobulin J Chain1 2
IGCJ2 3
JCH2

External Ids:    HGNC: 57131   Entrez Gene: 35122   Ensembl: ENSG000001324657   OMIM: 1477905   UniProtKB: P015913   

Export aliases for IGJ gene to outside databases

Previous GC identifers: GC04M071761 GC04M071922 GC04M071987 GC04M071886 GC04M067325


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for IGJ Gene: 
IGJ (immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides) is a protein-coding gene. Diseases associated with IGJ include renal artery obstruction, and fibromuscular dysplasia. GO annotations related to this gene include antigen binding.

UniProtKB/Swiss-Prot: IGJ_HUMAN, P01591
Function: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a
nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind
these immunoglobulins to secretory component

Gene Wiki entry for IGJ Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_022778.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IGJ gene promoter:
         Oct-B1   oct-B2   AML1a   FOXJ2 (long isoform)   Lmo2   FOXJ2   XBP-1   STAT5A   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIGJ promoter sequence
   Search SABiosciences Chromatin IP Primers for IGJ

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGJ


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21   Ensembl cytogenetic band:  4q13.3   HGNC cytogenetic band: 4q21

IGJ Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IGJ gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M071478:  view genomic region     (about GC identifiers)

Start:
71,521,258 bp from pter      End:
71,547,534 bp from pter
Size:
26,277 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: IGJ_HUMAN, P01591 (See protein sequence)
Recommended Name: Immunoglobulin J chain precursor  
Size: 159 amino acids; 18099 Da
Subcellular location: Secreted

Explore the universe of human proteins at neXtProt for IGJ: NX_P01591

Explore proteomics data for IGJ at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P01591

  • IGJ Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    IGJ Protein Expression
    REFSEQ proteins: NP_653247.1  
    ENSEMBL proteins: 
     ENSP00000254801   ENSP00000426687   ENSP00000427112   ENSP00000426045   ENSP00000417560  
     ENSP00000440066  

    Human Recombinant Protein Products for IGJ: 
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    Novus Biologicals IGJ Proteins
    Novus Biologicals IGJ Lysates
    Sino Biological Recombinant Protein for IGJ
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region NAS14718574

    IGJ for ontologies           About GeneDecksing



    IGJ Antibody Products: 
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    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    IGJ: Immunoglobulins / IGJ linker

    1 InterPro protein domain:
     IPR024110 Ig_J

    Graphical View of Domain Structure for InterPro Entry P01591

    ProtoNet protein and cluster: P01591


    IGJ for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IGJ_HUMAN, P01591
    Function: Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a
    nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind
    these immunoglobulins to secretory component

         Genatlas biochemistry entry for IGJ:
    immunoglobulin,J linker for alpha and mu chains

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003823antigen binding NAS2984306
         
    IGJ for ontologies           About GeneDecksing


    Phenotypes:
         7 MGI mutant phenotypes (inferred from 5 alleles(MGI details for Igj):
     digestive/alimentary  endocrine/exocrine gland  hematopoietic system  immune system  integument 
     liver/biliary system  mortality/aging 

    IGJ for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for IGJ: Igjtm1Jse Igjtm3Tl

       inGenious Targeting Laboratory - Custom generated mouse model solutions for IGJ 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for IGJ

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IGJ 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IGJ 

    miRNA
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate IGJ (see all 13):
    hsa-miR-607 hsa-miR-586 hsa-miR-128 hsa-miR-4306 hsa-miR-3681* hsa-miR-944 hsa-miR-138-2* hsa-miR-519e*
    SwitchGear 3'UTR luciferase reporter plasmidIGJ 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGJ

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    4 Interacting proteins for IGJ (P015913 ENSP000002548014) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CD79AP119123, ENSP000002219724I2D: score=2 STRING: ENSP00000221972
    IGHMP018713I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    --ENSP000004002554STRING: ENSP00000400255
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response NAS2984306

    IGJ for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IGJ

    Search CenterWatch for drugs/clinical trials and news about IGJ

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IGJ gene: 
    NM_144646.3  

    Unigene Cluster for IGJ:

    Immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
    Hs.643431  [show with all ESTs]
    Unigene Representative Sequence: BX648421
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000254801(uc003hfn.4 uc010ihz.3) ENST00000510437 ENST00000510614
    ENST00000391614 ENST00000470866 ENST00000543780
    miRNA
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    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate IGJ (see all 13):
    hsa-miR-607 hsa-miR-586 hsa-miR-128 hsa-miR-4306 hsa-miR-3681* hsa-miR-944 hsa-miR-138-2* hsa-miR-519e*
    SwitchGear 3'UTR luciferase reporter plasmidIGJ 3' UTR sequence
    Inhib. RNA
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    Primer
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGJ

    Additional mRNA sequence: 

    AK312014.1 BC038982.1 BX648421.1 DQ884395.1 

    17 DOTS entries:

    DT.416100  DT.92065006  DT.91693727  DT.100798803  DT.100798802  DT.100798805  DT.91778639  DT.99936961 
    DT.91778629  DT.95178305  DT.121262686  DT.121262694  DT.100681864  DT.121262700  DT.121262709  DT.121262680 
    DT.95178304 

    24/561 AceView cDNA sequences (see all 561):

    AA612781 BG540384 AA702681 BX119629 BG211934 BG206215 BP342631 BQ084295 
    AI660683 AI281423 BF173390 AA669281 AI285491 BP338894 AI280935 BF175642 
    BQ083258 BF174016 AI707707 AA294940 AW193310 BF174973 H64982 BQ082989 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for IGJ    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c
    SP1:        -     -           -                                 
    SP2:                                                            
    SP3:                          -                                 


    ECgene alternative splicing isoforms for IGJ

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IGJ expression in normal human tissues (normalized intensities)      IGJ embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTACGTATTC
    IGJ Expression
    About this image


    IGJ expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/18 selected tissues (see all 18) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 4 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
             lung ; macrophages   
             BONE MARROW   
     
     Intestine (Gastrointestinal Tract)    fully expand to see all 3 entries
             small intestine ; glandular cells   
             small intestine   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 2 entries
             rectum ; glandular cells   
     
     Oral Cavity (Gastrointestinal Tract)    fully expand to see all 2 entries
             salivary gland ; glandular cells   
             Salivary gland   
     
     Tonsil (Hematopoietic System)    fully expand to see all 2 entries
             tonsil ; non-germinal center cells   

    See IGJ Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IGJ

    SOURCE GeneReport for Unigene cluster: Hs.643431
        SABiosciences Custom PCR Arrays for IGJ
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for IGJ gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Igj1 , 5 immunoglobulin joining chain1, 5 82.49(n)1
    76.58(a)1
      5 (43.70 cM)5
    160691  NM_152839.31  NP_690052.21 
     885205125 
    chicken
    (Gallus gallus)
    Aves IGJ1 immunoglobulin J polypeptide, linker protein for immunoglobulin more 63.76(n)
    57.05(a)
      374117  NM_204263.1  NP_989594.1 
    lizard
    (Anolis carolinensis)
    Reptilia IGJ6
    immunoglobulin J polypeptide, linker protein for i...
    44(a)
    1 ↔ 1
    5(147078237-147093243)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.2612 Xenopus laevis immunoglobulin-associated J chain mRNA, more 77.71(n)    AF036547.1 


    ENSEMBL Gene Tree for IGJ (if available)
    TreeFam Gene Tree for IGJ (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IGJ gene

    IGJ for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for IGJ
    PGOHUM00000249416


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/320 SNPs in IGJ are shown (see all 320)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1829317501,2
    --71520768(+) TCTAGA/GTTAAA 1 -- int10--------
    rs168453021,2
    C,F,H--71520984(+) TCCATG/AGTACC 1 -- int117Minor allele frequency- A:0.15NA NS EA WA CSA 1633
    rs1134375491,2
    F--71521008(+) GTCAAC/TTGGCC 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs22882431,2
    F,H--71521112(-) GGTGGC/GTTTGC 1 -- int15Minor allele frequency- G:0.01EA NS 1898
    rs1133874611,2
    C--71521260(+) GTATAA/C/TGCTTA 2 -- ut311CSA 1
    rs759389001,2
    C,F--71521360(+) TCAAAT/GGGCAA 1 -- ut311Minor allele frequency- G:0.04WA 118
    rs1876867541,2
    C--71521456(+) CATTTA/TTTTTG 1 -- ut310--------
    rs1912170451,2
    --71521460(+) TATTTA/TGCTAC 1 -- ut310--------
    rs1498124391,2
    C--71521489(+) TTTCAC/GCTTAA 1 -- ut310--------
    rs794869501,2
    C,F--71521560(+) TATAAT/CTGACC 1 -- ut311Minor allele frequency- C:0.04WA 118

    HapMap Linkage Disequilibrium report for IGJ (71521258 - 71547534 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for IGJ:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv829965CNV Gain17160897

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 147790    OMIM disorders: --

    12 diseases for IGJ:    About MalaCards
    renal artery obstruction    fibromuscular dysplasia    keratopathy    tonsillitis
    duodenitis    atopic dermatitis    dermatitis    systemic lupus erythematosus
    lupus erythematosus    hepatitis b    myeloma    hepatitis


    IGJ for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: IGJ (2 documents)

    Export disorders for IGJ gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IGJ gene, integrated from 9 sources (see all 53):
    (articles sorted by number of sources associating them with IGJ)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human J chain gene. Structure and expression in B lymphoid cells. (PubMed id 2984306)1, 2, 3 Max E.E. and Korsmeyer S.J. (1985)
    2. Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. (PubMed id 16740002)1, 2 Ramachandran P....Loo J.A. (2006)
    3. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
    4. A proteomic analysis of human bile. (PubMed id 15084671)1, 2 Kristiansen T.Z.... Pandey A. (2004)
    5. Disulfide bond assignment in human J chain and its covalent pairing with immunoglobulin M. (PubMed id 1472500)1, 2 Frutiger S.... Jaton J.-C. (1992)
    6. Human J chain gene: chromosomal localization and associated restriction fragment length polymorphisms. (PubMed id 3016707)1, 3 Max E.E....Robinson M.A. (1986)
    7. Primary structure of human J chain: alignment of peptides from chemical and enzymatic hydrolyses. (PubMed id 407930)1, 2 Mole J.E.... Bennett J.C. (1977)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Toll-like receptor 2 induces mucosal homing receptor expression and IgA production by human B cells. (PubMed id 20947433)1 Liang Y....Ganley-Leal L.M. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3512 HGNC: 5713 AceView: IGJ Ensembl:ENSG00000132465 euGenes: HUgn3512
    ECgene: IGJ H-InvDB: IGJ

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IGJ Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IGJ gene:
    Search GeneIP for patents involving IGJ

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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