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Aliases for IGHV7-81 Gene

Aliases for IGHV7-81 Gene

  • Immunoglobulin Heavy Variable 7-81 (Non-Functional) 2 3 5
  • Immunoglobulin Heavy Variable 7-81 2
  • IGHV781 3

External Ids for IGHV7-81 Gene

Previous GeneCards Identifiers for IGHV7-81 Gene

  • GC14U990135
  • GC14M105051
  • GC14M105254
  • GC14M106353
  • GC14M107282
  • GC14M087435
  • GC14M107018
  • GC14M107756
  • GC14M107849
  • GC14M107948
  • GC14M108047

Summaries for IGHV7-81 Gene

GeneCards Summary for IGHV7-81 Gene

IGHV7-81 (Immunoglobulin Heavy Variable 7-81 (Non-Functional)) is a Protein Coding gene. An important paralog of this gene is IGHV7-4-1.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV7-81 Gene

Genomics for IGHV7-81 Gene

Regulatory Elements for IGHV7-81 Gene

Enhancers for IGHV7-81 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G106714 1 Ensembl ENCODE dbSUPER 5.1 +160.0 160023 1.7 EED ASH2L EBF1 TBX21 IGHV1-69 IGHV3-66 IGHV2-70D IGHV7-81 IGHV1-68
GH14G106872 1.2 Ensembl ENCODE 0.7 +1.9 1880 1.6 HDGF PKNOX1 FOXA2 ARID4B ZNF48 GLIS2 ZNF143 FOS SP3 REST IGHV2-70D IGHV7-81 IGHV4-80
GH14G106879 0.8 ENCODE 0.7 -4.3 -4318 0.2 ELF3 CTCF PKNOX1 RAD21 ZIC2 GLIS2 ZNF143 SMC3 PRDM10 CREM IGHV2-70D IGHVIII-82 IGHV7-81 IGH
GH14G106875 0.5 ENCODE 0.7 -0.6 -637 0.2 CTCF ZNF654 TRIM22 RAD21 IGHV2-70D IGHVIII-82 IGHV7-81 IGH
GH14G106877 0.4 ENCODE 0.7 -2.6 -2617 0.2 SP7 IGHVIII-82 IGHV7-81 IGH
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around IGHV7-81 on UCSC Golden Path with GeneCards custom track

Genomic Location for IGHV7-81 Gene

106,874,581 bp from pter
106,875,071 bp from pter
491 bases
Minus strand

Genomic View for IGHV7-81 Gene

Genes around IGHV7-81 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGHV7-81 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGHV7-81 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGHV7-81 Gene

Proteins for IGHV7-81 Gene

  • Protein details for IGHV7-81 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Immunoglobulin heavy variable 7-81 (non-functional)
    Protein Accession:

    Protein attributes for IGHV7-81 Gene

    117 amino acids
    Molecular mass:
    12918 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV7-81 Gene

Post-translational modifications for IGHV7-81 Gene

No Post-translational modifications

Other Protein References for IGHV7-81 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV7-81 Gene

Domains & Families for IGHV7-81 Gene

Gene Families for IGHV7-81 Gene

Protein Domains for IGHV7-81 Gene

Suggested Antigen Peptide Sequences for IGHV7-81 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGHV7-81: view

No data available for UniProtKB/Swiss-Prot for IGHV7-81 Gene

Function for IGHV7-81 Gene

Gene Ontology (GO) - Molecular Function for IGHV7-81 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0034987 immunoglobulin receptor binding IBA --
genes like me logo Genes that share ontologies with IGHV7-81: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGHV7-81 Gene

Localization for IGHV7-81 Gene

Gene Ontology (GO) - Cellular Components for IGHV7-81 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009897 external side of plasma membrane IBA --
GO:0042571 immunoglobulin complex, circulating IBA --
GO:0072562 blood microparticle IBA --
genes like me logo Genes that share ontologies with IGHV7-81: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for IGHV7-81 Gene

Pathways & Interactions for IGHV7-81 Gene

SuperPathways for IGHV7-81 Gene

No Data Available

Interacting Proteins for IGHV7-81 Gene

Gene Ontology (GO) - Biological Process for IGHV7-81 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006910 phagocytosis, recognition IBA --
GO:0006911 phagocytosis, engulfment IBA --
GO:0006958 complement activation, classical pathway IBA --
GO:0042742 defense response to bacterium IBA --
GO:0045087 innate immune response IBA --
genes like me logo Genes that share ontologies with IGHV7-81: view

No data available for Pathways by source and SIGNOR curated interactions for IGHV7-81 Gene

Drugs & Compounds for IGHV7-81 Gene

No Compound Related Data Available

Transcripts for IGHV7-81 Gene

mRNA/cDNA for IGHV7-81 Gene

(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV7-81 Gene

No ASD Table

Relevant External Links for IGHV7-81 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGHV7-81 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IGHV7-81 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV7-81 Gene

This gene is overexpressed in Colon - Transverse (x14.9), Bladder (x5.6), Small Intestine - Terminal Ileum (x5.3), and Kidney - Cortex (x4.6).

SOURCE GeneReport for Unigene cluster for IGHV7-81 Gene:

genes like me logo Genes that share expression patterns with IGHV7-81: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGHV7-81 Gene

Orthologs for IGHV7-81 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IGHV7-81 Gene

Organism Taxonomy Gene Similarity Type Details
(Monodelphis domestica)
Mammalia -- 35
  • 31 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 28 (a)
(Gallus gallus)
Aves -- 35
  • 13 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 48 (a)
(Danio rerio)
Actinopterygii ighv4-1 35
  • 34 (a)
Species where no ortholog for IGHV7-81 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IGHV7-81 Gene

Gene Tree for IGHV7-81 (if available)
Gene Tree for IGHV7-81 (if available)

Paralogs for IGHV7-81 Gene Pseudogenes for IGHV7-81 Gene

genes like me logo Genes that share paralogs with IGHV7-81: view

Variants for IGHV7-81 Gene

Relevant External Links for IGHV7-81 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGHV7-81 Gene

Disorders for IGHV7-81 Gene

Relevant External Links for IGHV7-81

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for IGHV7-81 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGHV7-81 Gene

Publications for IGHV7-81 Gene

  1. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S. … Sun P. (Mol. Immunol. 2002) 3 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  3. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. (PMID: 9841928) Matsuda F. … Honjo T. (J. Exp. Med. 1998) 3 64
  4. A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q. (PMID: 7920635) Cook G.P. … Rabbitts T.H. (Nat. Genet. 1994) 3 64
  5. Physicochemical and functional characterization of the C1r subunit of the first complement component. (PMID: 814163) Ziccardi R.J. … Cooper N.R. (J. Immunol. 1976) 3 64

Products for IGHV7-81 Gene

Sources for IGHV7-81 Gene

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