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Aliases for IGHV7-81 Gene

Aliases for IGHV7-81 Gene

  • Immunoglobulin Heavy Variable 7-81 (Non-Functional) 2 3 5
  • Immunoglobulin Heavy Variable 7-81 2
  • IGHV781 3

External Ids for IGHV7-81 Gene

Previous GeneCards Identifiers for IGHV7-81 Gene

  • GC14U990135
  • GC14M105051
  • GC14M105254
  • GC14M106353
  • GC14M107282
  • GC14M087435
  • GC14M107018
  • GC14M107756
  • GC14M107849
  • GC14M107948
  • GC14M108047
  • GC14M108164
  • GC14M108303

Summaries for IGHV7-81 Gene

GeneCards Summary for IGHV7-81 Gene

IGHV7-81 (Immunoglobulin Heavy Variable 7-81 (Non-Functional)) is a Protein Coding gene. An important paralog of this gene is IGHV7-4-1.

Additional gene information for IGHV7-81 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV7-81 Gene

Genomics for IGHV7-81 Gene

GeneHancer (GH) Regulatory Elements for IGHV7-81 Gene

Promoters and enhancers for IGHV7-81 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I106872 Enhancer 1.1 Ensembl ENCODE 550.8 +1.9 1880 1.6 HDGF PKNOX1 FOXA2 ARID4B NEUROD1 ZNF48 GLIS2 ZNF143 FOS RUNX3 IGHV4-80 IGHV7-81 IGHV2-70D IGH
GH14I106875 Enhancer 0.5 ENCODE 550.8 -0.6 -637 0.2 CTCF ZNF654 TRIM22 RAD21 IGHV7-81 IGHV2-70D IGH IGHVIII-82
GH14I106874 Enhancer 0.4 ENCODE 550.8 +0.5 544 0.2 POLR2A RUNX3 IGHV4-80 IGHV7-81 IGH
GH14I106714 Enhancer 0.8 Ensembl ENCODE dbSUPER 5.1 +160.0 160022 1.7 POLR2A EBF1 IGHV1-69 IGHV3-66 IGHV2-70D IGHV7-81 IGHV1-68 GC14M108467 IGH
GH14I106879 Enhancer 0.7 ENCODE 0.8 -4.3 -4318 0.2 ELF3 CTCF PKNOX1 ZIC2 RAD21 GLIS2 ZNF143 PRDM10 ZNF444 KLF13 IGH IGHVIII-82 IGHV2-70D IGHV7-81
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around IGHV7-81 on UCSC Golden Path with GeneCards custom track

Genomic Locations for IGHV7-81 Gene

Genomic Locations for IGHV7-81 Gene
chr14:106,874,581-106,875,071
(GRCh38/hg38)
Size:
491 bases
Orientation:
Minus strand
chr14:107,282,790-107,283,280
(GRCh37/hg19)

Genomic View for IGHV7-81 Gene

Genes around IGHV7-81 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGHV7-81 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGHV7-81 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGHV7-81 Gene

Proteins for IGHV7-81 Gene

  • Protein details for IGHV7-81 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J1V7
    Recommended name:
    Immunoglobulin heavy variable 7-81 (non-functional)
    Protein Accession:
    A0A0B4J1V7

    Protein attributes for IGHV7-81 Gene

    Size:
    117 amino acids
    Molecular mass:
    12918 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV7-81 Gene

Post-translational modifications for IGHV7-81 Gene

No Post-translational modifications

Other Protein References for IGHV7-81 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV7-81 Gene

Domains & Families for IGHV7-81 Gene

Gene Families for IGHV7-81 Gene

Protein Domains for IGHV7-81 Gene

Suggested Antigen Peptide Sequences for IGHV7-81 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGHV7-81: view

No data available for UniProtKB/Swiss-Prot for IGHV7-81 Gene

Function for IGHV7-81 Gene

Gene Ontology (GO) - Molecular Function for IGHV7-81 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0034987 immunoglobulin receptor binding IBA --
genes like me logo Genes that share ontologies with IGHV7-81: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGHV7-81 Gene

Localization for IGHV7-81 Gene

Gene Ontology (GO) - Cellular Components for IGHV7-81 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009897 external side of plasma membrane IBA --
GO:0042571 immunoglobulin complex, circulating IBA --
GO:0072562 blood microparticle IBA --
genes like me logo Genes that share ontologies with IGHV7-81: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for IGHV7-81 Gene

Pathways & Interactions for IGHV7-81 Gene

SuperPathways for IGHV7-81 Gene

No Data Available

Interacting Proteins for IGHV7-81 Gene

Gene Ontology (GO) - Biological Process for IGHV7-81 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006910 phagocytosis, recognition IBA --
GO:0006911 phagocytosis, engulfment IBA --
GO:0006958 complement activation, classical pathway IBA --
GO:0042742 defense response to bacterium IBA --
GO:0045087 innate immune response IBA --
genes like me logo Genes that share ontologies with IGHV7-81: view

No data available for Pathways by source and SIGNOR curated interactions for IGHV7-81 Gene

Drugs & Compounds for IGHV7-81 Gene

No Compound Related Data Available

Transcripts for IGHV7-81 Gene

mRNA/cDNA for IGHV7-81 Gene

(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV7-81 Gene

No ASD Table

Relevant External Links for IGHV7-81 Gene

GeneLoc Exon Structure for
IGHV7-81
ECgene alternative splicing isoforms for
IGHV7-81

Expression for IGHV7-81 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IGHV7-81 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV7-81 Gene

This gene is overexpressed in Colon - Transverse (x14.9), Bladder (x5.6), Small Intestine - Terminal Ileum (x5.3), and Kidney - Cortex (x4.6).

SOURCE GeneReport for Unigene cluster for IGHV7-81 Gene:

Hs.737487
genes like me logo Genes that share expression patterns with IGHV7-81: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGHV7-81 Gene

Orthologs for IGHV7-81 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IGHV7-81 Gene

Organism Taxonomy Gene Similarity Type Details
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 31 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 28 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 34
  • 13 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 48 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ighv4-1 34
  • 34 (a)
ManyToMany
Species where no ortholog for IGHV7-81 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IGHV7-81 Gene

ENSEMBL:
Gene Tree for IGHV7-81 (if available)
TreeFam:
Gene Tree for IGHV7-81 (if available)

Paralogs for IGHV7-81 Gene

Pseudogenes.org Pseudogenes for IGHV7-81 Gene

genes like me logo Genes that share paralogs with IGHV7-81: view

Variants for IGHV7-81 Gene

Additional Variant Information for IGHV7-81 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
IGHV7-81

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGHV7-81 Gene

Disorders for IGHV7-81 Gene

Additional Disease Information for IGHV7-81

No disorders were found for IGHV7-81 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGHV7-81 Gene

Publications for IGHV7-81 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58
  2. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S … Sun P (Molecular immunology 2002) 3 58
  3. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. (PMID: 9841928) Matsuda F … Honjo T (The Journal of experimental medicine 1998) 3 58
  4. A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q. (PMID: 7920635) Cook GP … Rabbitts TH (Nature genetics 1994) 3 58
  5. Activation of C1r by proteolytic cleavage. (PMID: 1249422) Ziccardi RJ … Cooper NR (Journal of immunology (Baltimore, Md. : 1950) 1976) 3 58

Products for IGHV7-81 Gene

Sources for IGHV7-81 Gene

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