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Aliases for IGHV6-1 Gene

Aliases for IGHV6-1 Gene

  • Immunoglobulin Heavy Variable 6-1 2 3 5
  • Immunogloblin Heavy Chain Variable Region 3
  • IGHV61 3
  • VH 3

External Ids for IGHV6-1 Gene

Previous GeneCards Identifiers for IGHV6-1 Gene

  • GC14U990141
  • GC14M104377
  • GC14M105476
  • GC14M106408
  • GC14M086538
  • GC14M106414
  • GC14M106418
  • GC14M106459
  • GC14M106524
  • GC14M106742
  • GC14M107399
  • GC14M107591

Summaries for IGHV6-1 Gene

GeneCards Summary for IGHV6-1 Gene

IGHV6-1 (Immunoglobulin Heavy Variable 6-1) is a Protein Coding gene. An important paralog of this gene is IGHV4-61.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV6-1 Gene

Genomics for IGHV6-1 Gene

Regulatory Elements for IGHV6-1 Gene

Enhancers for IGHV6-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F105944 1 Ensembl ENCODE 0.8 -4.8 -4848 0.6 CTCF SAP130 ZIC2 ZNF2 RAD21 ZFHX2 ZBTB48 ZNF143 SMC3 KLF13 IGHV6-1 IGHVII-1-1
GH14F105945 0.6 ENCODE 0.8 -4.2 -4165 0.2 TFAP4 MAZ ZNF654 SAP130 SP5 TRIM22 HNF4A IGHV6-1 IGHVII-1-1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around IGHV6-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for IGHV6-1 Gene

105,939,754 bp from pter
105,940,253 bp from pter
500 bases
Minus strand

Genomic View for IGHV6-1 Gene

Genes around IGHV6-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGHV6-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGHV6-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGHV6-1 Gene

Proteins for IGHV6-1 Gene

  • Protein details for IGHV6-1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein IGHV6-1
    Protein Accession:

    Protein attributes for IGHV6-1 Gene

    121 amino acids
    Molecular mass:
    13481 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV6-1 Gene

Post-translational modifications for IGHV6-1 Gene

No Post-translational modifications

Other Protein References for IGHV6-1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV6-1 Gene

Domains & Families for IGHV6-1 Gene

Gene Families for IGHV6-1 Gene

Protein Domains for IGHV6-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGHV6-1: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGHV6-1 Gene

Function for IGHV6-1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGHV6-1 Gene

Localization for IGHV6-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGHV6-1 Gene

Pathways & Interactions for IGHV6-1 Gene

SuperPathways for IGHV6-1 Gene

No Data Available

Interacting Proteins for IGHV6-1 Gene

Gene Ontology (GO) - Biological Process for IGHV6-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for IGHV6-1 Gene

Transcripts for IGHV6-1 Gene

mRNA/cDNA for IGHV6-1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV6-1 Gene

No ASD Table

Relevant External Links for IGHV6-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGHV6-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IGHV6-1 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV6-1 Gene

This gene is overexpressed in Spleen (x26.9) and Colon - Transverse (x6.3).
genes like me logo Genes that share expression patterns with IGHV6-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for IGHV6-1 Gene

Orthologs for IGHV6-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IGHV6-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 53 (a)
-- 35
  • 48 (a)
-- 35
  • 47 (a)
-- 35
  • 43 (a)
-- 35
  • 42 (a)
-- 35
  • 40 (a)
(Gallus gallus)
Aves -- 35
  • 32 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 42 (a)
-- 35
  • 38 (a)
(Danio rerio)
Actinopterygii ighv5-2 35
  • 39 (a)
ighv5-7 35
  • 39 (a)
ighv7-1 35
  • 39 (a)
ighv5-1 35
  • 37 (a)
ighv8-1 35
  • 36 (a)
ighv5-3 35
  • 35 (a)
ighv5-5 35
  • 35 (a)
ighv5-4 35
  • 34 (a)
ighv8-2 35
  • 34 (a)
ighv8-4 35
  • 34 (a)
ighv5-8 35
  • 33 (a)
ighv8-3 35
  • 33 (a)
Species where no ortholog for IGHV6-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IGHV6-1 Gene

Gene Tree for IGHV6-1 (if available)
Gene Tree for IGHV6-1 (if available)

Paralogs for IGHV6-1 Gene

Variants for IGHV6-1 Gene

Relevant External Links for IGHV6-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGHV6-1 Gene

Disorders for IGHV6-1 Gene

No disorders were found for IGHV6-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGHV6-1 Gene

Publications for IGHV6-1 Gene

  1. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. (PMID: 9841928) Matsuda F. … Honjo T. (J. Exp. Med. 1998) 3 64
  2. The use of chromosomal translocations to study human immunoglobulin gene organization: mapping DH segments within 35 kb of the C mu gene and identification of a new DH locus. (PMID: 3138112) Buluwela L. … Rabbitts T.H. (EMBO J. 1988) 3 64
  3. Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus. (PMID: 3396540) Berman J.E. … Cantor C.R. (EMBO J. 1988) 3 64

Products for IGHV6-1 Gene

Sources for IGHV6-1 Gene

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