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Aliases for IGHV4-31 Gene

Aliases for IGHV4-31 Gene

  • Immunoglobulin Heavy Variable 4-31 2 3 5
  • Anti-RhD Monoclonal T125 Gamma1 Heavy Chain 3
  • IGHV431 3

External Ids for IGHV4-31 Gene

Previous GeneCards Identifiers for IGHV4-31 Gene

  • GC14U990152
  • GC14M104776
  • GC14M105876
  • GC14M106806
  • GC14M086942
  • GC14M106831
  • GC14M106861
  • GC14M106894
  • GC14M106940
  • GC14M107292
  • GC14M107448
  • GC14M107640
  • GC14M106529
  • GC14M107554
  • GC14M107818
  • GC14M107917

Summaries for IGHV4-31 Gene

GeneCards Summary for IGHV4-31 Gene

IGHV4-31 (Immunoglobulin Heavy Variable 4-31) is a Protein Coding gene. An important paralog of this gene is IGHV4-61.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV4-31 Gene

Genomics for IGHV4-31 Gene

Regulatory Elements for IGHV4-31 Gene

Enhancers for IGHV4-31 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F106348 1.1 Ensembl ENCODE 0.8 +0.4 419 0.9 ELF3 INSM2 KLF17 RAD21 ZNF207 KLF7 ZNF391 EGR2 ZNF263 SP3 IGHV3-30-2 IGHV4-31
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around IGHV4-31 on UCSC Golden Path with GeneCards custom track

Genomic Location for IGHV4-31 Gene

106,349,283 bp from pter
106,349,792 bp from pter
510 bases
Minus strand

Genomic View for IGHV4-31 Gene

Genes around IGHV4-31 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGHV4-31 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGHV4-31 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for IGHV4-31 Gene

Proteins for IGHV4-31 Gene

  • Protein details for IGHV4-31 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein IGHV4-31
    Protein Accession:

    Protein attributes for IGHV4-31 Gene

    118 amino acids
    Molecular mass:
    13025 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV4-31 Gene

Post-translational modifications for IGHV4-31 Gene

No Post-translational modifications

Other Protein References for IGHV4-31 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV4-31 Gene

Domains & Families for IGHV4-31 Gene

Gene Families for IGHV4-31 Gene

Protein Domains for IGHV4-31 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGHV4-31: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGHV4-31 Gene

Function for IGHV4-31 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGHV4-31 Gene

Localization for IGHV4-31 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGHV4-31 Gene

Pathways & Interactions for IGHV4-31 Gene

SuperPathways for IGHV4-31 Gene

No Data Available

Interacting Proteins for IGHV4-31 Gene

Gene Ontology (GO) - Biological Process for IGHV4-31 Gene


No data available for Pathways by source and SIGNOR curated interactions for IGHV4-31 Gene

Transcripts for IGHV4-31 Gene

mRNA/cDNA for IGHV4-31 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV4-31 Gene

No ASD Table

Relevant External Links for IGHV4-31 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGHV4-31 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IGHV4-31 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV4-31 Gene

This gene is overexpressed in Spleen (x14.2) and Colon - Transverse (x4.9).

Protein differential expression in normal tissues from HIPED for IGHV4-31 Gene

This gene is overexpressed in Urine (46.2) and Serum (22.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for IGHV4-31 Gene

Protein tissue co-expression partners for IGHV4-31 Gene

- Elite partner
genes like me logo Genes that share expression patterns with IGHV4-31: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGHV4-31 Gene

Orthologs for IGHV4-31 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGHV4-31 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 35
  • 54 (a)
Species where no ortholog for IGHV4-31 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGHV4-31 Gene

Gene Tree for IGHV4-31 (if available)
Gene Tree for IGHV4-31 (if available)

Paralogs for IGHV4-31 Gene Pseudogenes for IGHV4-31 Gene

genes like me logo Genes that share paralogs with IGHV4-31: view

Variants for IGHV4-31 Gene

Relevant External Links for IGHV4-31 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGHV4-31 Gene

Disorders for IGHV4-31 Gene

Relevant External Links for IGHV4-31

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for IGHV4-31 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGHV4-31 Gene

Publications for IGHV4-31 Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  2. Immunoglobulin gamma heavy chain gene with somatic hypermutation is frequently expressed in acute myeloid leukemia. (PMID: 22772058) Qiu X. … Yin C.C. (Leukemia 2013) 3 64
  3. Selection of a human anti-RhD monoclonal antibody for therapeutic use: impact of IgG glycosylation on activating and inhibitory Fc gamma R functions. (PMID: 16332457) Siberil S. … Teillaud J.L. (Clin. Immunol. 2006) 3 64
  4. Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia. (PMID: 16112646) Guinn B.-A. … Mufti G.J. (Biochem. Biophys. Res. Commun. 2005) 3 64
  5. Development of a cocktail of recombinant-expressed human rabies virus-neutralizing monoclonal antibodies for postexposure prophylaxis of rabies. (PMID: 12825170) Prosniak M. … Dietzschold B. (J. Infect. Dis. 2003) 3 64

Products for IGHV4-31 Gene

Sources for IGHV4-31 Gene

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