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Aliases for IGHV4-28 Gene

Aliases for IGHV4-28 Gene

  • Immunoglobulin Heavy Variable 4-28 2 3 5
  • Immunogloblin Heavy Chain Variable Region 3
  • IGHV428 3
  • VH 3

External Ids for IGHV4-28 Gene

Previous GeneCards Identifiers for IGHV4-28 Gene

  • GC14U990156
  • GC14M104752
  • GC14M105851
  • GC14M106781
  • GC14M086921
  • GC14M106965
  • GC14M107440
  • GC14M107632

Summaries for IGHV4-28 Gene

GeneCards Summary for IGHV4-28 Gene

IGHV4-28 (Immunoglobulin Heavy Variable 4-28) is a Protein Coding gene. An important paralog of this gene is IGHV4-39.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV4-28 Gene

Genomics for IGHV4-28 Gene

Genomic Location for IGHV4-28 Gene

106,324,254 bp from pter
106,324,760 bp from pter
507 bases
Minus strand

Genomic View for IGHV4-28 Gene

Genes around IGHV4-28 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGHV4-28 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGHV4-28 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGHV4-28 Gene

No data available for Regulatory Elements for IGHV4-28 Gene

Proteins for IGHV4-28 Gene

  • Protein details for IGHV4-28 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein IGHV4-28
    Protein Accession:

    Protein attributes for IGHV4-28 Gene

    117 amino acids
    Molecular mass:
    13124 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV4-28 Gene

Post-translational modifications for IGHV4-28 Gene

No Post-translational modifications

Other Protein References for IGHV4-28 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV4-28 Gene

Domains & Families for IGHV4-28 Gene

Gene Families for IGHV4-28 Gene

Protein Domains for IGHV4-28 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGHV4-28: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGHV4-28 Gene

Function for IGHV4-28 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGHV4-28 Gene

Localization for IGHV4-28 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGHV4-28 Gene

Pathways & Interactions for IGHV4-28 Gene

SuperPathways for IGHV4-28 Gene

No Data Available

Interacting Proteins for IGHV4-28 Gene

Gene Ontology (GO) - Biological Process for IGHV4-28 Gene


No data available for Pathways by source and SIGNOR curated interactions for IGHV4-28 Gene

Transcripts for IGHV4-28 Gene

mRNA/cDNA for IGHV4-28 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV4-28 Gene

No ASD Table

Relevant External Links for IGHV4-28 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGHV4-28 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IGHV4-28 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV4-28 Gene

This gene is overexpressed in Spleen (x17.8), Colon - Transverse (x5.4), and Small Intestine - Terminal Ileum (x4.5).

Protein differential expression in normal tissues from HIPED for IGHV4-28 Gene

This gene is overexpressed in Urine (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for IGHV4-28 Gene

Protein tissue co-expression partners for IGHV4-28 Gene

- Elite partner
genes like me logo Genes that share expression patterns with IGHV4-28: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGHV4-28 Gene

Orthologs for IGHV4-28 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGHV4-28 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 35
  • 51 (a)
Species where no ortholog for IGHV4-28 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGHV4-28 Gene

Gene Tree for IGHV4-28 (if available)
Gene Tree for IGHV4-28 (if available)

Paralogs for IGHV4-28 Gene

Variants for IGHV4-28 Gene

Relevant External Links for IGHV4-28 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGHV4-28 Gene

Disorders for IGHV4-28 Gene

Relevant External Links for IGHV4-28

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for IGHV4-28 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGHV4-28 Gene

Publications for IGHV4-28 Gene

  1. IGHV4-39 deletion polymorphism does not associate with risk or outcome of multiple sclerosis. (PMID: 20471699) Watson C.T. … Breden F. (J. Neuroimmunol. 2010) 3 46 64
  2. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. (PMID: 9841928) Matsuda F. … Honjo T. (J. Exp. Med. 1998) 3 64
  3. A novel family of variable region genes of the human immunoglobulin heavy chain. (PMID: 3116265) Lee K.H. … Honjo T. (J. Mol. Biol. 1987) 3 64

Products for IGHV4-28 Gene

Sources for IGHV4-28 Gene

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