IGHV3-48 Gene
protein-coding GIFtS : 21 GCID: GC14 M107014
immunoglobulin heavy variable 3-48
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Aliasesfor IGHV3-48 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Immunoglobulin Heavy Variable 3-48 1 2 IGHV3482 VH2
Export aliases for IGHV3-48 gene to outside databases Previous GC identifers: GC14U990180 GC14M104965 GC14M106045 GC14M106064 GC14M106994
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Summariesfor IGHV3-48 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section
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Genomic Viewsfor IGHV3-48 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000014.8 NC_018925.1 NT_026437.12 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for IGHV3-48 Other transcription factors Search SABiosciences Chromatin IP Primers for IGHV3-48 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGHV3-48
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 14q32.33 Ensembl cytogenetic band: 14q32.33 HGNC cytogenetic band: 14q32.33 IGHV3-48 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 14 GeneLoc Exon Structure
GeneLoc location for GC14M107014: view genomic region
(about GC identifiers )
Start: 106,993,812 bp from pter End:
106,994,346 bp from pter
Size: 535 bases Orientation:
minus strand
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Proteinsfor IGHV3-48 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB: --IGHV3-48 Protein expression data from MOPED and PaxDb : About this image ENSEMBL proteins: ENSP00000375033 Human Recombinant Protein Products for IGHV3-48: Antibody Products for IGHV3-48: Assay Products for IGHV3-48:
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Protein
Domains /for IGHV3-48 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
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Functionfor IGHV3-48 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Animal Models:
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Pathways & Interactionsfor IGHV3-48 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGHV3-48 STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)2 Interacting proteins for IGHV3-48 (ENSP00000375033 4 via UniProtKB, MINT, STRING , and/or I2D About this table
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Drugs & Compoundsfor IGHV3-48 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for IGHV3-48 IGHV3-48
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Transcriptsfor IGHV3-48 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section Unigene Cluster for IGHV3-48:
Immunoglobulin heavy variable 3-48 Hs.703936 [show with all ESTs ] Unigene Representative Sequence: BQ710261 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390624 Additional cDNA sequence: AB021525.1 AB063673.1 AB063699.1 AB063852.1 AB063908.1 AB063916.1 AB066888.1 AB067000.1 AB067076.1 AB067248.1 AB095277.1 AB363089.1 AB363090.1 AB363150.1 AB363160.1 AB363166.1 AB374202.1 AF006522.1 AF006525.1 AF021979.1 AF035023.1 AF035042.1 AF035787.1 AF035788.1 AF039297.1 AF052525.1 AF062095.1 AF062111.1 AF062118.1 AF062122.1 AF062168.1 AF062171.1 AF062182.1 AF062206.1 AF062215.1 AF062229.1 AF062235.1 AF062253.1 AF062285.1 AF082195.1 AF098362.1 AF103088.1 AF103183.1 AF103256.1 AF103319.1 AF103334.1 AF115123.1 AF174048.1 AF174059.1 AF174081.1 AF174100.1 AF174120.1 AF194121.1 AF233250.1 AF343368.1 AF343413.1 AF398962.1 AF408730.1 AF455546.1 AF455553.1 AF460663.1 AF460667.1 AF460670.1 AF460674.1 AF460676.1 AF460679.1 AF460695.1 AF460697.1 AF460705.1 AF460744.1 AF460754.1 AF460787.1 AF460805.1 AF460807.1 AJ008181.1 AJ008229.1 AJ010335.1 AJ239363.1 AJ239370.1 AJ239380.1 AJ239390.1 AJ245323.1 AJ245324.1 AJ249628.1 AJ271600.1 AJ278773.1 AJ300807.1 AJ389180.1 AJ389190.1 AJ399809.1 AJ413989.1 AJ413993.1 AJ488540.1 AJ548507.1 AJ556641.1 AJ556649.1 AJ579109.1 AJ579266.1 AJ627249.1 AM040520.1 AM183984.1 AM259133.1 AM259134.1 AY003743.1 AY003791.1 AY003800.1 AY003830.1 AY003838.1 AY003851.1 AY003858.1 AY190818.1 AY190822.1 AY392915.1 AY392925.1 AY423199.1 AY423205.1 AY423206.1 AY423208.1 AY466507.1 AY466509.1 AY487925.1 AY530312.1 AY530316.1 AY686909.1 AY686913.1 AY866555.1 AY866627.1 AY866657.1 AY866746.1 AY866759.1 AY866795.1 AY866807.1 AY921574.1 AY921575.1 AY941884.1 AY941887.1 AY941891.1 AY941906.1 AY941912.1 AY941915.1 D83682.1 DQ001066.1 DQ065617.1 DQ065642.1 DQ097899.1 DQ100686.1 DQ100778.1 DQ100793.1 DQ100804.1 DQ100813.1 DQ100818.1 DQ100900.1 DQ100905.1 DQ100909.1 DQ100918.1 DQ100981.1 DQ187519.1 DQ187673.1 DQ187706.1 DQ187711.1 DQ187712.1 DQ205182.1 DQ322877.1 DQ322968.1 DQ322969.1 DQ322970.1 DQ322971.1 DQ322972.1 DQ322973.1 DQ322974.1 DQ431493.1 DQ431495.1 DQ454386.1 DQ454538.1 DQ454540.1 DQ454541.1 DQ454554.1 DQ454585.1 DQ454592.1 DQ454598.1 DQ454606.1 DQ454615.1 DQ454621.1 DQ454628.1 DQ454655.1 DQ454676.1 DQ454740.1 DQ454788.1 DQ454805.1 DQ455001.1 DQ523858.1 DQ523867.1 DQ523869.1 DQ523873.1 DQ523889.1 DQ523892.1 DQ523925.1 DQ523926.1 DQ524024.1 DQ524134.1 DQ524162.1 DQ535286.1 DQ535300.1 DQ535354.1 DQ535377.1 DQ535410.1 DQ535419.1 DQ535472.1 EF175387.1 EF175393.1 EF175410.1 EF175424.1 EF407843.1 EF441748.1 EF555586.1 EU099077.1 EU099084.1 EU099085.1 EU099094.1 EU099148.1 EU099149.1 EU099150.1 EU099151.1 EU099187.1 EU099223.1 EU099261.1 EU146317.1 EU146321.1 EU146347.1 EU146389.1 EU350424.1 EU549721.1 EU667609.1 FJ195522.1 FJ385329.1 FJ385334.1 FJ385335.1 FJ385338.1 FJ385339.1 FJ385347.1 FJ385349.1 FJ385400.1 FJ694884.1 FJ773245.1 FJ773246.1 FJ840063.1 FJ840064.1 FJ840091.1 FJ840092.1 FJ840093.1 FJ840096.1 FJ840098.1 FJ840112.1 FJ840147.1 FJ840240.1 FJ840275.1 FJ840277.1 FJ840278.1 FJ840279.1 FJ840280.1 FJ840281.1 FJ840282.1 FJ840283.1 FJ840285.1 FJ840286.1 FJ840288.1 FJ840289.1 FJ840290.1 FJ840291.1 FJ840294.1 FJ840295.1 FJ840296.1 FJ840298.1 FJ840299.1 FJ840300.1 FJ840301.1 FJ840303.1 FJ840322.1 FJ840340.1 FJ873823.1 FJ873826.1 FJ873838.1 FJ873839.1 FJ873840.1 FJ873846.1 FJ873876.1 FJ873886.1 FJ873897.1 FJ873926.1 FJ873933.1 FJ873934.1 FJ873963.1 FJ873992.1 FJ874019.1 FJ874031.1 FJ874050.1 FJ874058.1 GQ504915.1 GQ504957.1 GU358679.1 GU552701.1 GU552709.1 GU552713.1 GU552719.1 GU552720.1 GU552754.1 GU552767.1 GU570335.1 GU570338.1 GU570340.1 GU570341.1 GU570343.1 GU570348.1 GU570355.1 GU570357.1 HM116214.1 HM152495.1 HM152503.1 HM152510.1 HM451460.1 HM773967.1 HM774086.1 HM774115.1 HM774125.1 HM774238.1 HM774429.1 HM774436.1 HM774562.1 HM774566.1 HM774593.1 HM774600.1 HM774870.1 HM774996.1 HM775035.1 HM994897.1 HM994907.1 HM995019.1 HM995157.1 HM995353.1 HM995355.1 HM995441.1 HM995442.1 HM995443.1 HM995444.1 HM995445.1 HM995446.1 HM995470.1 HM995471.1 HM995475.1 HM995476.1 HM995521.1 HM995666.1 HM995667.1 HM995668.1 HM995874.1 HM995884.1 HM995887.1 HM995888.1 HM995889.1 HM995890.1 HM995891.1 HM995892.1 HM995901.1 HM995906.1 HM995907.1 HM995919.1 HM995935.1 HM995953.1 HM995965.1 HM996019.1 HM996054.1 HM996247.1 HM996347.1 HQ392877.1 HQ704000.1 HQ704008.1 HQ704009.1 HQ704018.1 HQ704046.1 JF810268.1 JF810270.1 JN110472.1 JN110479.1 JN110485.1 JN110521.1 JN110541.1 JN110571.1 JN110593.1 JN110620.1 JN110658.1 JN110671.1 JN110706.1 JN110718.1 JN110930.1 JN376163.1 JN376416.1 JN376546.1 JX420412.1 JX462753.1 L07311.1 L08082.1 L08085.1 M18520.1 M18521.1 S73143.1 S76131.1 S85238.1 U00490.1 U00498.1 U00501.1 U00540.1 U00563.1 U00567.1 U77374.1 X59134.1 X59703.1 X61011.1 X61021.1 X62958.1 X64243.1 X77472.1 X81724.1 X81725.1 X81729.1 X81730.1 X81735.1 X81739.1 X81751.1 X99353.1 Z11947.1 Z18317.1 Z18824.1 Z33898.1 Z33902.1 Z33904.1 Z46764.1 Z96964.1
24/235 DOTS entries (see all 235 ): DT.95368001 DT.100848453 DT.100034793 DT.100812214 DT.121506974 DT.121650665 DT.100043941 DT.100775361
DT.121507007 DT.121640455 DT.91691002 DT.100666904 DT.121652227 DT.95244849 DT.100033024 DT.100849604 DT.101986183 DT.121506680 DT.121507183 DT.121508132 DT.121508705 DT.121508825 DT.121509487 DT.121509594 24/261 AceView cDNA sequences (see all 261 ):
AL560682 S73508 BX248300 BX360630 AL560681 AF460776 AW401419 T27727 Z75391 AW402332 AW405472 U44493 BV167396 BE241696 AW403144 X67906 AI863827 AF062305 AF174119 AB066892 U77559 U00553 U77551 AF174097 GeneLoc Exon Structure
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Expression for IGHV3-48 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section IGHV3-48 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AGCTGGGTCCAbout this image See IGHV3-48 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for IGHV3-48 SOURCE GeneReport for Unigene cluster: Hs.703936 SABiosciences Custom PCR Arrays for IGHV3-48
Primer Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat IGHV3-48 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGHV3-48 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGHV3-48
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Orthologsfor IGHV3-48 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for IGHV3-48 gene from 3/6 species (see all 6 ) About this table
ENSEMBL Gene Tree for IGHV3-48 (if available)TreeFam Gene Tree for IGHV3-48 (if available)
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Paralogsfor IGHV3-48 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for IGHV3-48 gene IGHV3-43 2 IGHV3-53 2 IGHV3-9 2 IGHV3-21 2 IGHV3-73 2 IGHV3-7 2 IGHV3-30 2 IGHV3-23 2 IGHV3-72 2 IGHV3-33 2 IGHV3-66 2 IGHV3-11 2 IGHV3-20 2 IGHV3-74 2 IGHV3-16 2 IGHV3-64 2 IGHV3-13 2 IGHV3-38 2 IGHV3-15 2 IGHV3-49 2 ENSG00000223931 2 IGHV3-35 2 About GeneDecksing
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Genomic Variantsfor IGHV3-48 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor IGHV3-48 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
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Publicationsfor IGHV3-48 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for IGHV3-48 gene integrated from 9 sources :(articles sorted by number of sources associating them with IGHV3-48) Utopia : connect your pdf to the dynamic
The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. (PubMed id 9841928) 1 (1998) Myosin-reactive autoantibodies in rheumatic carditis and normal fetus. (PubMed id 9614934) 1 (1998) Structure and physical map of 64 variable segments in the 3'0.8-megabase region of the human immunoglobulin heavy-chain locus. (PubMed id 8490662) 1 (1993)
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External Searches for IGHV3-48 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing IGHV3-48 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing IGHV3-48 gene
(According to HUGE )
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Specialized Databases showing IGHV3-48 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for IGHV3-48 Pharmacogenomics, SNPs, Pathways IMGT entry for IGHV3-48The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section Patent Information for IGHV3-48 gene: IGHV3-48 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor IGHV3-48 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IGHV3-48 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGHV3-48 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGHV3-48 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGHV3-48 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGHV3-48 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGHV3-48
Search ThermoFisher Antibodies for IGHV3-48
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat IGHV3-48
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