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Aliases for IGHV3-23 Gene

Aliases for IGHV3-23 Gene

  • Immunoglobulin Heavy Variable 3-23 2 3
  • IGHV323 3 6
  • DP47 3 6
  • VH26 3 6
  • Mu-Chain Precursor (AA -19 To 142) 3
  • V3-23 3

External Ids for IGHV3-23 Gene

Previous GeneCards Identifiers for IGHV3-23 Gene

  • GC14U990198
  • GC14M104696
  • GC14M105796
  • GC14M106726
  • GC14M086866
  • GC14M106729
  • GC14M107433
  • GC14M107625

Summaries for IGHV3-23 Gene

Entrez Gene Summary for IGHV3-23 Gene

  • IGHV3-23 belongs to a cluster of approximately 40 functional variable (V) genes in the immunoglobulin (Ig) heavy chain locus on chromosome 14. For background information on the Ig heavy chain and the V gene cluster, see (MIM 147070).[supplied by OMIM, Apr 2008]

GeneCards Summary for IGHV3-23 Gene

IGHV3-23 (Immunoglobulin Heavy Variable 3-23) is a Protein Coding gene. Among its related pathways are PI-3K cascade and PI-3K cascade. GO annotations related to this gene include antigen binding. An important paralog of this gene is IGHV3OR16-9.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV3-23 Gene

Genomics for IGHV3-23 Gene

Genomic Location for IGHV3-23 Gene

Start:
106,268,606 bp from pter
End:
106,269,140 bp from pter
Size:
535 bases
Orientation:
Minus strand

Genomic View for IGHV3-23 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IGHV3-23 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGHV3-23 Gene

No data available for Regulatory Elements for IGHV3-23 Gene

Proteins for IGHV3-23 Gene

  • Protein details for IGHV3-23 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087WSX3
    Recommended name:
    Protein IGHV3-23
    Protein Accession:
    A0A087WSX3
    Secondary Accessions:

    Protein attributes for IGHV3-23 Gene

    Size:
    117 amino acids
    Molecular mass:
    12582 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV3-23 Gene

Proteomics data for IGHV3-23 Gene at MOPED

Post-translational modifications for IGHV3-23 Gene

No Post-translational modifications

Other Protein References for IGHV3-23 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV3-23 Gene

Domains for IGHV3-23 Gene

Gene Families for IGHV3-23 Gene

HGNC:
  • IGH :Immunoglobulins / IGH locus

Protein Domains for IGHV3-23 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGHV3-23: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGHV3-23 Gene

Function for IGHV3-23 Gene

Gene Ontology (GO) - Molecular Function for IGHV3-23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003823 antigen binding NAS 6450418
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IGHV3-23: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for IGHV3-23 Gene

Localization for IGHV3-23 Gene

Gene Ontology (GO) - Cellular Components for IGHV3-23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005886 plasma membrane TAS --
GO:0070062 extracellular exosome IDA 23376485
GO:0072562 blood microparticle IDA 22516433
genes like me logo Genes that share ontologies with IGHV3-23: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for IGHV3-23 Gene

Pathways for IGHV3-23 Gene

genes like me logo Genes that share pathways with IGHV3-23: view

Interacting Proteins for IGHV3-23 Gene

Gene Ontology (GO) - Biological Process for IGHV3-23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006898 receptor-mediated endocytosis TAS --
GO:0006955 immune response NAS 6450418
GO:0006956 complement activation TAS --
GO:0006958 complement activation, classical pathway TAS --
GO:0038095 Fc-epsilon receptor signaling pathway TAS --
genes like me logo Genes that share ontologies with IGHV3-23: view

Transcripts for IGHV3-23 Gene

mRNA/cDNA for IGHV3-23 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV3-23 Gene

No ASD Table

Relevant External Links for IGHV3-23 Gene

GeneLoc Exon Structure for
IGHV3-23
ECgene alternative splicing isoforms for
IGHV3-23

Expression for IGHV3-23 Gene

mRNA expression in normal human tissues for IGHV3-23 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV3-23 Gene

This gene is overexpressed in Spleen (12.0) and Colon - Transverse (7.8).

Integrated Proteomics: protein expression from for IGHV3-23 Gene

genes like me logo Genes that share expressions with IGHV3-23: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGHV3-23 Gene

Orthologs for IGHV3-23 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGHV3-23 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 36
  • 73 (a)
ManyToMany
Species with no ortholog for IGHV3-23:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGHV3-23 Gene

ENSEMBL:
Gene Tree for IGHV3-23 (if available)
TreeFam:
Gene Tree for IGHV3-23 (if available)

Paralogs for IGHV3-23 Gene

genes like me logo Genes that share paralogs with IGHV3-23: view

Variants for IGHV3-23 Gene

Relevant External Links for IGHV3-23 Gene

HapMap Linkage Disequilibrium report
IGHV3-23

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for IGHV3-23 Gene

Disorders for IGHV3-23 Gene

No disorders were found for IGHV3-23 Gene.

No data available for UniProtKB/Swiss-Prot for IGHV3-23 Gene

Publications for IGHV3-23 Gene

  1. Physicochemical and functional characterization of the C1r subunit of the first complement component. (PMID: 814163) Ziccardi R.J. … Cooper N.R. (J. Immunol. 1976) 3
  2. Activation of C1r by proteolytic cleavage. (PMID: 1249422) Ziccardi R.J. … Cooper N.R. (J. Immunol. 1976) 3
  3. Organization and sequences of the diversity, joining, and constant region genes of the human T-cell receptor beta chain. (PMID: 3866244) Toyonaga B. … Mak T.W. (Proc. Natl. Acad. Sci. U.S.A. 1985) 3
  4. Structure and multiplicity of genes for the human immunoglobulin heavy chain variable region. (PMID: 6450418) Matthyssens G. … Rabbitts T.H. (Proc. Natl. Acad. Sci. U.S.A. 1980) 3
  5. Nucleotidic sequence analysis of the variable domains of four human monoclonal IgM with an antibody activity to myelin-associated glycoprotein. (PMID: 7681398) Mariette X. … Brouet J.C. (Eur. J. Immunol. 1993) 3

Products for IGHV3-23 Gene

Sources for IGHV3-23 Gene

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