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Aliases for IGHV3-23 Gene

Aliases for IGHV3-23 Gene

  • Immunoglobulin Heavy Variable 3-23 2 3 4 5
  • Mu-Chain Precursor (AA -19 To 142) 3
  • Ig Heavy Chain V-III Region VH26 4
  • IGHV323 3
  • V3-23 3
  • DP47 3
  • VH26 3

External Ids for IGHV3-23 Gene

Previous GeneCards Identifiers for IGHV3-23 Gene

  • GC14U990198
  • GC14M104696
  • GC14M105796
  • GC14M106726
  • GC14M086866
  • GC14M106729
  • GC14M107433
  • GC14M107625

Summaries for IGHV3-23 Gene

Entrez Gene Summary for IGHV3-23 Gene

  • IGHV3-23 belongs to a cluster of approximately 40 functional variable (V) genes in the immunoglobulin (Ig) heavy chain locus on chromosome 14. For background information on the Ig heavy chain and the V gene cluster, see (MIM 147070).[supplied by OMIM, Apr 2008]

GeneCards Summary for IGHV3-23 Gene

IGHV3-23 (Immunoglobulin Heavy Variable 3-23) is a Protein Coding gene. Among its related pathways are Immune response Role of DAP12 receptors in NK cells and Development Angiotensin activation of ERK. GO annotations related to this gene include antigen binding. An important paralog of this gene is IGHV3OR16-9.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV3-23 Gene

Genomics for IGHV3-23 Gene

Regulatory Elements for IGHV3-23 Gene

Promoters for IGHV3-23 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around IGHV3-23 on UCSC Golden Path with GeneCards custom track

Genomic Location for IGHV3-23 Gene

Chromosome:
14
Start:
106,268,606 bp from pter
End:
106,269,140 bp from pter
Size:
535 bases
Orientation:
Minus strand

Genomic View for IGHV3-23 Gene

Genes around IGHV3-23 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGHV3-23 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGHV3-23 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGHV3-23 Gene

Proteins for IGHV3-23 Gene

  • Protein details for IGHV3-23 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P01764-HV303_HUMAN
    Recommended name:
    Ig heavy chain V-III region 23
    Protein Accession:
    P01764
    Secondary Accessions:
    • A0A087WSX3

    Protein attributes for IGHV3-23 Gene

    Size:
    117 amino acids
    Molecular mass:
    12582 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for IGHV3-23 Gene

neXtProt entry for IGHV3-23 Gene

Proteomics data for IGHV3-23 Gene at MOPED

Post-translational modifications for IGHV3-23 Gene

No Post-translational modifications

Other Protein References for IGHV3-23 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV3-23 Gene

Domains & Families for IGHV3-23 Gene

Gene Families for IGHV3-23 Gene

Protein Domains for IGHV3-23 Gene

Graphical View of Domain Structure for InterPro Entry

P01764

UniProtKB/Swiss-Prot:

HV303_HUMAN :
  • Contains 1 Ig-like (immunoglobulin-like) domain.
Domain:
  • Contains 1 Ig-like (immunoglobulin-like) domain.
genes like me logo Genes that share domains with IGHV3-23: view

No data available for Suggested Antigen Peptide Sequences for IGHV3-23 Gene

Function for IGHV3-23 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGHV3-23 Gene

Localization for IGHV3-23 Gene

Gene Ontology (GO) - Cellular Components for IGHV3-23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009897 external side of plasma membrane IBA --
genes like me logo Genes that share ontologies with IGHV3-23: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for IGHV3-23 Gene

Pathways & Interactions for IGHV3-23 Gene

genes like me logo Genes that share pathways with IGHV3-23: view

Interacting Proteins for IGHV3-23 Gene

Selected Interacting proteins: P01764-HV303_HUMAN for IGHV3-23 Gene via I2D

Symbol External ID(s) Details
IGHG1
--
  • P01600 21

Gene Ontology (GO) - Biological Process for IGHV3-23 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis TAS --
GO:0006956 complement activation TAS --
GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis TAS --
GO:0045087 innate immune response IBA,TAS --
GO:0050871 positive regulation of B cell activation IBA --
genes like me logo Genes that share ontologies with IGHV3-23: view

No data available for SIGNOR curated interactions for IGHV3-23 Gene

Drugs & Compounds for IGHV3-23 Gene

No Compound Related Data Available

Transcripts for IGHV3-23 Gene

mRNA/cDNA for IGHV3-23 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV3-23 Gene

No ASD Table

Relevant External Links for IGHV3-23 Gene

GeneLoc Exon Structure for
IGHV3-23
ECgene alternative splicing isoforms for
IGHV3-23

Expression for IGHV3-23 Gene

mRNA expression in normal human tissues for IGHV3-23 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV3-23 Gene

This gene is overexpressed in Spleen (x12.0) and Colon - Transverse (x7.8).

Protein differential expression in normal tissues from HIPED for IGHV3-23 Gene

This gene is overexpressed in Serum (40.0) and Urine (22.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IGHV3-23 Gene



genes like me logo Genes that share expression patterns with IGHV3-23: view

Protein tissue co-expression partners for IGHV3-23 Gene

- Elite partner

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGHV3-23 Gene

Orthologs for IGHV3-23 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGHV3-23 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 36
  • 73 (a)
ManyToMany
Species with no ortholog for IGHV3-23:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGHV3-23 Gene

ENSEMBL:
Gene Tree for IGHV3-23 (if available)
TreeFam:
Gene Tree for IGHV3-23 (if available)

Paralogs for IGHV3-23 Gene

genes like me logo Genes that share paralogs with IGHV3-23: view

Variants for IGHV3-23 Gene

Sequence variations from dbSNP and Humsavar for IGHV3-23 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
VAR_073326 -
VAR_073327 -

Relevant External Links for IGHV3-23 Gene

HapMap Linkage Disequilibrium report
IGHV3-23

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGHV3-23 Gene

Disorders for IGHV3-23 Gene

Relevant External Links for IGHV3-23

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
IGHV3-23

No disorders were found for IGHV3-23 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGHV3-23 Gene

Publications for IGHV3-23 Gene

  1. Nucleotidic sequence analysis of the variable domains of four human monoclonal IgM with an antibody activity to myelin-associated glycoprotein. (PMID: 7681398) Mariette X. … Brouet J.C. (Eur. J. Immunol. 1993) 3 4 67
  2. The central role of EED in the orchestration of polycomb group complexes. (PMID: 24457600) Cao Q. … Chinnaiyan A.M. (Nat Commun 2014) 3
  3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3
  4. Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. (PMID: 22516433) Bastos-Amador P. … Falcon-Perez J.M. (J Proteomics 2012) 3
  5. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S. … Sun P. (Mol. Immunol. 2002) 3

Products for IGHV3-23 Gene

Sources for IGHV3-23 Gene

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