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Aliases for IGHV3-16 Gene

Aliases for IGHV3-16 Gene

  • Immunoglobulin Heavy Variable 3-16 (Non-Functional) 2 3 5
  • Immunogloblin Heavy Chain Variable Region 3
  • Immunoglobulin Heavy Variable 3-16 2
  • IGHV316 3
  • VH 3

External Ids for IGHV3-16 Gene

Previous GeneCards Identifiers for IGHV3-16 Gene

  • GC14U990203
  • GC14M104593
  • GC14M105681
  • GC14M105692
  • GC14M106623
  • GC14M086762
  • GC14M106625
  • GC14M106659
  • GC14M106784
  • GC14M107420
  • GC14M107612

Summaries for IGHV3-16 Gene

GeneCards Summary for IGHV3-16 Gene

IGHV3-16 (Immunoglobulin Heavy Variable 3-16 (Non-Functional)) is a Protein Coding gene. An important paralog of this gene is IGHV3-38.

Additional gene information for IGHV3-16 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV3-16 Gene

Genomics for IGHV3-16 Gene

GeneHancer (GH) Regulatory Elements for IGHV3-16 Gene

Promoters and enhancers for IGHV3-16 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I106165 Enhancer 0.5 dbSUPER 550.8 -0.7 -680 0.9 MITF NR2F1 CREB1 MNT IGHV3-16 IGHVIII-16-1 IGH
GH14I106164 Enhancer 0.3 dbSUPER 550.8 +1.0 979 1.1 CTCF IGHV3-16 IGHVII-15-1 IGH
GH14I106170 Enhancer 0.6 ENCODE 0.8 -4.5 -4516 0.2 SMARCA5 GTF2F1 CTCF MAZ RB1 TRIM22 ZNF592 RLF ZNF143 ZNF444 IGHVIII-16-1 IGHV3-16 IGH
GH14I106168 Enhancer 0.2 dbSUPER 0.8 -3.4 -3391 0.7 IGHVIII-16-1 IGHV3-16 IGH
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around IGHV3-16 on UCSC Golden Path with GeneCards custom track

Genomic Locations for IGHV3-16 Gene

Genomic Locations for IGHV3-16 Gene
528 bases
Minus strand

Genomic View for IGHV3-16 Gene

Genes around IGHV3-16 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGHV3-16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGHV3-16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGHV3-16 Gene

Proteins for IGHV3-16 Gene

  • Protein details for IGHV3-16 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Immunoglobulin heavy variable 3-16 (non-functional)
    Protein Accession:

    Protein attributes for IGHV3-16 Gene

    117 amino acids
    Molecular mass:
    13070 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV3-16 Gene

Post-translational modifications for IGHV3-16 Gene

No Post-translational modifications

Other Protein References for IGHV3-16 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV3-16 Gene

Domains & Families for IGHV3-16 Gene

Gene Families for IGHV3-16 Gene

Protein Domains for IGHV3-16 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGHV3-16: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGHV3-16 Gene

Function for IGHV3-16 Gene

Gene Ontology (GO) - Molecular Function for IGHV3-16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0034987 immunoglobulin receptor binding IBA --
genes like me logo Genes that share ontologies with IGHV3-16: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGHV3-16 Gene

Localization for IGHV3-16 Gene

Gene Ontology (GO) - Cellular Components for IGHV3-16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009897 external side of plasma membrane IBA --
GO:0042571 immunoglobulin complex, circulating IBA --
GO:0072562 blood microparticle IBA --
genes like me logo Genes that share ontologies with IGHV3-16: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for IGHV3-16 Gene

Pathways & Interactions for IGHV3-16 Gene

SuperPathways for IGHV3-16 Gene

No Data Available

Interacting Proteins for IGHV3-16 Gene

Gene Ontology (GO) - Biological Process for IGHV3-16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006910 phagocytosis, recognition IBA --
GO:0006911 phagocytosis, engulfment IBA --
GO:0006958 complement activation, classical pathway IBA --
GO:0042742 defense response to bacterium IBA --
GO:0045087 innate immune response IBA --
genes like me logo Genes that share ontologies with IGHV3-16: view

No data available for Pathways by source and SIGNOR curated interactions for IGHV3-16 Gene

Drugs & Compounds for IGHV3-16 Gene

No Compound Related Data Available

Transcripts for IGHV3-16 Gene

mRNA/cDNA for IGHV3-16 Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV3-16 Gene

No ASD Table

Relevant External Links for IGHV3-16 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGHV3-16 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IGHV3-16 Gene

Protein differential expression in normal tissues from HIPED for IGHV3-16 Gene

This gene is overexpressed in Saliva (30.0), Urine (25.2), and Serum (10.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for IGHV3-16 Gene

Protein tissue co-expression partners for IGHV3-16 Gene

genes like me logo Genes that share expression patterns with IGHV3-16: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGHV3-16 Gene

Orthologs for IGHV3-16 Gene

This gene was present in the common ancestor of mammals.

Orthologs for IGHV3-16 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia -- 34
  • 59 (a)
Species where no ortholog for IGHV3-16 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for IGHV3-16 Gene

Gene Tree for IGHV3-16 (if available)
Gene Tree for IGHV3-16 (if available)

Paralogs for IGHV3-16 Gene

Paralogs for IGHV3-16 Gene Pseudogenes for IGHV3-16 Gene

genes like me logo Genes that share paralogs with IGHV3-16: view

Variants for IGHV3-16 Gene

Additional Variant Information for IGHV3-16 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGHV3-16 Gene

Disorders for IGHV3-16 Gene

No disorders were found for IGHV3-16 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGHV3-16 Gene

Publications for IGHV3-16 Gene

  1. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. (PMID: 9841928) Matsuda F … Honjo T (The Journal of experimental medicine 1998) 3 58
  2. Structure and physical map of 64 variable segments in the 3'0.8-megabase region of the human immunoglobulin heavy-chain locus. (PMID: 8490662) Matsuda F … Anand R (Nature genetics 1993) 3 58

Products for IGHV3-16 Gene

Sources for IGHV3-16 Gene

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