Free for academic non-profit institutions. Other users need a Commercial license

Aliases for IGHV2-70 Gene

Aliases for IGHV2-70 Gene

  • Immunoglobulin Heavy Variable 2-70 2 3 5
  • Immunogloblin Heavy Chain Variable Region 3
  • Ig Heavy Chain V-II Region 3
  • IGHV270 3
  • VH 3

External Ids for IGHV2-70 Gene

Previous GeneCards Identifiers for IGHV2-70 Gene

  • GC14U990210
  • GC14M105150
  • GC14M106249
  • GC14M107179
  • GC14M107220
  • GC14M107356
  • GC14M107512
  • GC14M107704
  • GC14M107002
  • GC14M107744

Summaries for IGHV2-70 Gene

GeneCards Summary for IGHV2-70 Gene

IGHV2-70 (Immunoglobulin Heavy Variable 2-70) is a Protein Coding gene. Among its related pathways are Immune System and Regulation of actin dynamics for phagocytic cup formation. GO annotations related to this gene include antigen binding. An important paralog of this gene is IGHV4-31.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV2-70 Gene

Genomics for IGHV2-70 Gene

Genomic Location for IGHV2-70 Gene

Chromosome:
14
Start:
106,770,577 bp from pter
End:
106,771,020 bp from pter
Size:
444 bases
Orientation:
Minus strand

Genomic View for IGHV2-70 Gene

Genes around IGHV2-70 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGHV2-70 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGHV2-70 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGHV2-70 Gene

No data available for Regulatory Elements for IGHV2-70 Gene

Proteins for IGHV2-70 Gene

  • Protein details for IGHV2-70 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J2H3
    Recommended name:
    Protein IGHV2-70
    Protein Accession:
    A0A0B4J2H3

    Protein attributes for IGHV2-70 Gene

    Size:
    119 amino acids
    Molecular mass:
    13260 Da
    Quaternary structure:
    No Data Available
  • Protein details for IGHV2-70 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0J9YVU5
    Recommended name:
    Protein IGHV2-70
    Protein Accession:
    A0A0J9YVU5

    Protein attributes for IGHV2-70 Gene

    Size:
    119 amino acids
    Molecular mass:
    13359 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV2-70 Gene

Proteomics data for IGHV2-70 Gene at MOPED

Post-translational modifications for IGHV2-70 Gene

No Post-translational modifications

Other Protein References for IGHV2-70 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV2-70 Gene

Domains & Families for IGHV2-70 Gene

Gene Families for IGHV2-70 Gene

Protein Domains for IGHV2-70 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGHV2-70: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGHV2-70 Gene

Function for IGHV2-70 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGHV2-70 Gene

Localization for IGHV2-70 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IGHV2-70 Gene

Pathways & Interactions for IGHV2-70 Gene

genes like me logo Genes that share pathways with IGHV2-70: view

Interacting Proteins for IGHV2-70 Gene

Gene Ontology (GO) - Biological Process for IGHV2-70 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006898 receptor-mediated endocytosis TAS --
GO:0006955 immune response NAS 5449120
GO:0006956 complement activation TAS --
genes like me logo Genes that share ontologies with IGHV2-70: view

No data available for SIGNOR curated interactions for IGHV2-70 Gene

Drugs & Compounds for IGHV2-70 Gene

No Compound Related Data Available

Transcripts for IGHV2-70 Gene

mRNA/cDNA for IGHV2-70 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV2-70 Gene

No ASD Table

Relevant External Links for IGHV2-70 Gene

GeneLoc Exon Structure for
IGHV2-70
ECgene alternative splicing isoforms for
IGHV2-70

Expression for IGHV2-70 Gene

mRNA expression in normal human tissues for IGHV2-70 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV2-70 Gene

This gene is overexpressed in Spleen (x18.1), Minor Salivary Gland (x7.0), and Colon - Transverse (x5.1).
genes like me logo Genes that share expression patterns with IGHV2-70: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for IGHV2-70 Gene

Orthologs for IGHV2-70 Gene

Evolution for IGHV2-70 Gene

ENSEMBL:
Gene Tree for IGHV2-70 (if available)
TreeFam:
Gene Tree for IGHV2-70 (if available)

No data available for Orthologs for IGHV2-70 Gene

Paralogs for IGHV2-70 Gene

genes like me logo Genes that share paralogs with IGHV2-70: view

Variants for IGHV2-70 Gene

Relevant External Links for IGHV2-70 Gene

HapMap Linkage Disequilibrium report
IGHV2-70

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGHV2-70 Gene

Disorders for IGHV2-70 Gene

No disorders were found for IGHV2-70 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGHV2-70 Gene

Publications for IGHV2-70 Gene

  1. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S. … Sun P. (Mol. Immunol. 2002) 3 67
  2. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. (PMID: 9841928) Matsuda F. … Honjo T. (J. Exp. Med. 1998) 3
  3. Molecular characterization of human antibodies to bacterial antigens: utilization of the less frequently expressed VH2 and VH6 heavy chain variable region gene families. (PMID: 8247031) Andris J.S. … Capra J.D. (Mol. Immunol. 1993) 3
  4. Physicochemical and functional characterization of the C1r subunit of the first complement component. (PMID: 814163) Ziccardi R.J. … Cooper N.R. (J. Immunol. 1976) 3
  5. The amino acid sequences of the Fd fragments of two human gamma-1 heavy chains. (PMID: 5449120) Press E.M. … Hogg N.M. (Biochem. J. 1970) 3

Products for IGHV2-70 Gene

Sources for IGHV2-70 Gene

Back to Top

Content