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Aliases for IGHV2-70 Gene

Aliases for IGHV2-70 Gene

  • Immunoglobulin Heavy Variable 2-70 2 3 5
  • Immunogloblin Heavy Chain Variable Region 3
  • Ig Heavy Chain V-II Region 3
  • IGHV270 3
  • VH 3

External Ids for IGHV2-70 Gene

Previous GeneCards Identifiers for IGHV2-70 Gene

  • GC14U990210
  • GC14M105150
  • GC14M106249
  • GC14M107179
  • GC14M107220
  • GC14M107356
  • GC14M107512
  • GC14M107704
  • GC14M107002
  • GC14M107744
  • GC14M107837

Summaries for IGHV2-70 Gene

GeneCards Summary for IGHV2-70 Gene

IGHV2-70 (Immunoglobulin Heavy Variable 2-70) is a Protein Coding gene. Among its related pathways are Interleukin-3, 5 and GM-CSF signaling and Vesicle-mediated transport. GO annotations related to this gene include antigen binding. An important paralog of this gene is ENSG00000211974.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV2-70 Gene

Genomics for IGHV2-70 Gene

Regulatory Elements for IGHV2-70 Gene

Enhancers for IGHV2-70 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around IGHV2-70 on UCSC Golden Path with GeneCards custom track

Genomic Location for IGHV2-70 Gene

Chromosome:
14
Start:
106,770,577 bp from pter
End:
106,771,020 bp from pter
Size:
444 bases
Orientation:
Minus strand

Genomic View for IGHV2-70 Gene

Genes around IGHV2-70 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGHV2-70 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGHV2-70 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGHV2-70 Gene

Proteins for IGHV2-70 Gene

  • Protein details for IGHV2-70 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J2H3
    Recommended name:
    Protein IGHV2-70
    Protein Accession:
    A0A0B4J2H3

    Protein attributes for IGHV2-70 Gene

    Size:
    119 amino acids
    Molecular mass:
    13260 Da
    Quaternary structure:
    No Data Available
  • Protein details for IGHV2-70 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0J9YVU5
    Recommended name:
    Protein IGHV2-70
    Protein Accession:
    A0A0J9YVU5

    Protein attributes for IGHV2-70 Gene

    Size:
    119 amino acids
    Molecular mass:
    13359 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV2-70 Gene

Post-translational modifications for IGHV2-70 Gene

No Post-translational modifications

Other Protein References for IGHV2-70 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV2-70 Gene

Domains & Families for IGHV2-70 Gene

Gene Families for IGHV2-70 Gene

Protein Domains for IGHV2-70 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGHV2-70: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGHV2-70 Gene

Function for IGHV2-70 Gene

Gene Ontology (GO) - Molecular Function for IGHV2-70 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003823 antigen binding NAS 5449120
GO:0004252 serine-type endopeptidase activity TAS --
genes like me logo Genes that share ontologies with IGHV2-70: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGHV2-70 Gene

Localization for IGHV2-70 Gene

Gene Ontology (GO) - Cellular Components for IGHV2-70 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005886 plasma membrane TAS --
genes like me logo Genes that share ontologies with IGHV2-70: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for IGHV2-70 Gene

Pathways & Interactions for IGHV2-70 Gene

genes like me logo Genes that share pathways with IGHV2-70: view

Interacting Proteins for IGHV2-70 Gene

Gene Ontology (GO) - Biological Process for IGHV2-70 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
GO:0006898 receptor-mediated endocytosis TAS --
GO:0006955 immune response NAS 5449120
GO:0006956 complement activation TAS --
GO:0006958 complement activation, classical pathway TAS --
genes like me logo Genes that share ontologies with IGHV2-70: view

No data available for SIGNOR curated interactions for IGHV2-70 Gene

Drugs & Compounds for IGHV2-70 Gene

No Compound Related Data Available

Transcripts for IGHV2-70 Gene

mRNA/cDNA for IGHV2-70 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV2-70 Gene

No ASD Table

Relevant External Links for IGHV2-70 Gene

GeneLoc Exon Structure for
IGHV2-70
ECgene alternative splicing isoforms for
IGHV2-70

Expression for IGHV2-70 Gene

mRNA expression in normal human tissues for IGHV2-70 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV2-70 Gene

This gene is overexpressed in Spleen (x18.1), Minor Salivary Gland (x7.0), and Colon - Transverse (x5.1).
genes like me logo Genes that share expression patterns with IGHV2-70: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for IGHV2-70 Gene

Orthologs for IGHV2-70 Gene

Evolution for IGHV2-70 Gene

ENSEMBL:
Gene Tree for IGHV2-70 (if available)
TreeFam:
Gene Tree for IGHV2-70 (if available)

No data available for Orthologs for IGHV2-70 Gene

Paralogs for IGHV2-70 Gene

genes like me logo Genes that share paralogs with IGHV2-70: view

Variants for IGHV2-70 Gene

Relevant External Links for IGHV2-70 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
IGHV2-70

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGHV2-70 Gene

Disorders for IGHV2-70 Gene

No disorders were found for IGHV2-70 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for IGHV2-70 Gene

Publications for IGHV2-70 Gene

  1. Recognition of immunoglobulins by Fcgamma receptors. (PMID: 11955599) Radaev S. … Sun P. (Mol. Immunol. 2002) 3 65
  2. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. (PMID: 9841928) Matsuda F. … Honjo T. (J. Exp. Med. 1998) 3 65
  3. Molecular characterization of human antibodies to bacterial antigens: utilization of the less frequently expressed VH2 and VH6 heavy chain variable region gene families. (PMID: 8247031) Andris J.S. … Capra J.D. (Mol. Immunol. 1993) 3 65
  4. Physicochemical and functional characterization of the C1r subunit of the first complement component. (PMID: 814163) Ziccardi R.J. … Cooper N.R. (J. Immunol. 1976) 3 65
  5. The amino acid sequences of the Fd fragments of two human gamma-1 heavy chains. (PMID: 5449120) Press E.M. … Hogg N.M. (Biochem. J. 1970) 3 65

Products for IGHV2-70 Gene

Sources for IGHV2-70 Gene

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