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Aliases for IGHV1OR15-1 Gene

Aliases for IGHV1OR15-1 Gene

  • Immunoglobulin Heavy Variable 1/OR15-1 (Non-Functional) 2 3 5
  • Immunoglobulin Heavy Variable 1/OR15-1 Pseudogene 2 3
  • Immunoglobulin Heavy Variable 1/OR15-1 (Pseudogene) 2
  • Immunoglobulin Heavy Variable 1/OR15-1 2
  • IGHV1/OR15-1 3
  • IGHV1OR151 3

External Ids for IGHV1OR15-1 Gene

Previous GeneCards Identifiers for IGHV1OR15-1 Gene

  • GC15U990092
  • GC15M019951
  • GC15M022448

Summaries for IGHV1OR15-1 Gene

GeneCards Summary for IGHV1OR15-1 Gene

IGHV1OR15-1 (Immunoglobulin Heavy Variable 1/OR15-1 (Non-Functional)) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include antigen binding. An important paralog of this gene is LOC102724760.

Additional gene information for IGHV1OR15-1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV1OR15-1 Gene

Genomics for IGHV1OR15-1 Gene

GeneHancer (GH) Regulatory Elements for IGHV1OR15-1 Gene

Promoters and enhancers for IGHV1OR15-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I022157 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 550.8 -0.3 -256 6.6 CTCF PKNOX1 SMAD1 RB1 BACH1 EBF1 KLF5 FOXK2 POLR2A ZNF207 IGHV1OR15-1 OR4N4 GC15M022187
GH15I022173 Enhancer 1.1 ENCODE dbSUPER 0.4 -12.5 -12529 1.2 PKNOX1 IRF4 ZNF207 ZNF143 ATF7 RUNX3 ZC3H11A REST ZNF592 ZNF184 GC15M022187 IGHV1OR15-1
GH15I022154 Enhancer 1 ENCODE dbSUPER 0.4 +5.4 5393 2 HDAC1 MEIS2 PKNOX1 LEF1 TEAD4 TAL1 TCF12 CTBP1 ZNF316 NCOR1 RPS8P10 IGHV1OR15-1
GH15I022174 Enhancer 0.9 ENCODE dbSUPER 0.4 -13.4 -13371 0.2 CTCF RB1 IRF3 EBF1 KLF5 RAD21 ZNF207 ZNF143 ZNF444 BCLAF1 IGHV1OR15-1 GC15M022187
GH15I022177 Enhancer 0.9 Ensembl ENCODE dbSUPER 0.4 -18.2 -18151 3.4 CTCF ZNF654 RB1 TRIM22 USF2 REST GC15M022187 LOC642131 IGHV1OR15-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around IGHV1OR15-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for IGHV1OR15-1 Gene

Genomic Locations for IGHV1OR15-1 Gene
chr15:22,160,288-22,160,934
(GRCh38/hg38)
Size:
647 bases
Orientation:
Minus strand
chr15:22,448,372-22,448,819
(GRCh37/hg19)

Genomic View for IGHV1OR15-1 Gene

Genes around IGHV1OR15-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGHV1OR15-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGHV1OR15-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGHV1OR15-1 Gene

Proteins for IGHV1OR15-1 Gene

  • Protein details for IGHV1OR15-1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B7D0
    Recommended name:
    Immunoglobulin heavy variable 1/OR15-1 (non-functional)
    Protein Accession:
    A0A075B7D0

    Protein attributes for IGHV1OR15-1 Gene

    Size:
    117 amino acids
    Molecular mass:
    13012 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV1OR15-1 Gene

Post-translational modifications for IGHV1OR15-1 Gene

No Post-translational modifications

Other Protein References for IGHV1OR15-1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV1OR15-1 Gene

Domains & Families for IGHV1OR15-1 Gene

Gene Families for IGHV1OR15-1 Gene

Protein Domains for IGHV1OR15-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGHV1OR15-1: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for IGHV1OR15-1 Gene

Function for IGHV1OR15-1 Gene

Gene Ontology (GO) - Molecular Function for IGHV1OR15-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003823 antigen binding NAS 2841108
GO:0004252 serine-type endopeptidase activity TAS --
GO:0034987 immunoglobulin receptor binding IBA --
genes like me logo Genes that share ontologies with IGHV1OR15-1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IGHV1OR15-1 Gene

Localization for IGHV1OR15-1 Gene

Gene Ontology (GO) - Cellular Components for IGHV1OR15-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005886 plasma membrane TAS --
GO:0009897 external side of plasma membrane IBA --
GO:0042571 immunoglobulin complex, circulating IBA --
GO:0072562 blood microparticle IBA --
genes like me logo Genes that share ontologies with IGHV1OR15-1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for IGHV1OR15-1 Gene

Pathways & Interactions for IGHV1OR15-1 Gene

SuperPathways for IGHV1OR15-1 Gene

No Data Available

Interacting Proteins for IGHV1OR15-1 Gene

Gene Ontology (GO) - Biological Process for IGHV1OR15-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
GO:0006898 receptor-mediated endocytosis TAS --
GO:0006910 phagocytosis, recognition IBA --
GO:0006911 phagocytosis, engulfment IBA --
GO:0006955 immune response NAS 2841108
genes like me logo Genes that share ontologies with IGHV1OR15-1: view

No data available for Pathways by source and SIGNOR curated interactions for IGHV1OR15-1 Gene

Drugs & Compounds for IGHV1OR15-1 Gene

No Compound Related Data Available

Transcripts for IGHV1OR15-1 Gene

mRNA/cDNA for IGHV1OR15-1 Gene

(8) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV1OR15-1 Gene

No ASD Table

Relevant External Links for IGHV1OR15-1 Gene

GeneLoc Exon Structure for
IGHV1OR15-1
ECgene alternative splicing isoforms for
IGHV1OR15-1

Expression for IGHV1OR15-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for IGHV1OR15-1 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV1OR15-1 Gene

This gene is overexpressed in Spleen (x9.1) and Small Intestine - Terminal Ileum (x4.6).
genes like me logo Genes that share expression patterns with IGHV1OR15-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for IGHV1OR15-1 Gene

Orthologs for IGHV1OR15-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IGHV1OR15-1 Gene

Organism Taxonomy Gene Similarity Type Details
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 35 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 28 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 34
  • 31 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 52 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ighv9-2 34
  • 35 (a)
ManyToMany
Species where no ortholog for IGHV1OR15-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IGHV1OR15-1 Gene

ENSEMBL:
Gene Tree for IGHV1OR15-1 (if available)
TreeFam:
Gene Tree for IGHV1OR15-1 (if available)

Paralogs for IGHV1OR15-1 Gene

Variants for IGHV1OR15-1 Gene

Sequence variations from dbSNP and Humsavar for IGHV1OR15-1 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000002633 -- 22,161,376(-) G/A upstream_transcript_variant
rs1000118358 -- 22,162,884(-) T/C upstream_transcript_variant
rs1000266762 -- 22,160,251(-) T/C downstream_transcript_variant
rs1012830676 -- 22,161,063(-) G/A upstream_transcript_variant
rs1012841777 -- 22,159,990(-) A/T downstream_transcript_variant

Additional Variant Information for IGHV1OR15-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
IGHV1OR15-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for IGHV1OR15-1 Gene

Disorders for IGHV1OR15-1 Gene

Additional Disease Information for IGHV1OR15-1

No disorders were found for IGHV1OR15-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGHV1OR15-1 Gene

Publications for IGHV1OR15-1 Gene

  1. Human immunoglobulin VH and D segments on chromosomes 15q11.2 and 16p11.2. (PMID: 7951227) Tomlinson IM … Winter G (Human molecular genetics 1994) 3 58
  2. Nucleotidic sequence analysis of the variable domains of four human monoclonal IgM with an antibody activity to myelin-associated glycoprotein. (PMID: 7681398) Mariette X … Brouet JC (European journal of immunology 1993) 3 58
  3. Dispersed localization of D segments in the human immunoglobulin heavy-chain locus. (PMID: 2841108) Matsuda F … Honjo T (The EMBO journal 1988) 3 58
  4. Cloning and sequence determination of the gene for the human immunoglobulin epsilon chain expressed in a myeloma cell line. (PMID: 6815656) Kenten JH … Gould HJ (Proceedings of the National Academy of Sciences of the United States of America 1982) 3 58

Products for IGHV1OR15-1 Gene

Sources for IGHV1OR15-1 Gene

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