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Aliases for IGHV1-2 Gene

Aliases for IGHV1-2 Gene

  • Immunoglobulin Heavy Variable 1-2 2 3
  • IGHV12 3
  • V35 3

External Ids for IGHV1-2 Gene

Summaries for IGHV1-2 Gene

GeneCards Summary for IGHV1-2 Gene

IGHV1-2 (Immunoglobulin Heavy Variable 1-2) is a Protein Coding gene. Diseases associated with IGHV1-2 include alpha chain disease and small intestine lymphoma. An important paralog of this gene is IGHV1-24.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGHV1-2 Gene

Genomics for IGHV1-2 Gene

Genomic Location for IGHV1-2 Gene

Start:
105,986,582 bp from pter
End:
105,987,083 bp from pter
Size:
502 bases
Orientation:
Minus strand

Genomic View for IGHV1-2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for IGHV1-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGHV1-2 Gene

No data available for Regulatory Elements for IGHV1-2 Gene

Proteins for IGHV1-2 Gene

  • Protein details for IGHV1-2 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A087WSX2-A0A087WSX2
    Recommended name:
    Protein IGHV1-2
    Protein Accession:
    A0A087WSX2
    Secondary Accessions:

    Protein attributes for IGHV1-2 Gene

    Size:
    117 amino acids
    Molecular mass:
    13085 Da
    Quaternary structure:
    No Data Available

neXtProt entry for IGHV1-2 Gene

Proteomics data for IGHV1-2 Gene at MOPED

Post-translational modifications for IGHV1-2 Gene

No Post-translational modifications

Other Protein References for IGHV1-2 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for IGHV1-2 Gene

Domains for IGHV1-2 Gene

Gene Families for IGHV1-2 Gene

HGNC:
  • IGH :Immunoglobulins / IGH locus

Protein Domains for IGHV1-2 Gene

genes like me logo Genes that share domains with IGHV1-2: view

No data available for UniProtKB/Swiss-Prot for IGHV1-2 Gene

Function for IGHV1-2 Gene

Gene Ontology (GO) - Molecular Function for IGHV1-2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with IGHV1-2: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for IGHV1-2 Gene

Localization for IGHV1-2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for IGHV1-2 Gene COMPARTMENTS Subcellular localization image for IGHV1-2 gene
Compartment Confidence
extracellular 5
cytoskeleton 2
peroxisome 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for IGHV1-2 Gene

Pathways for IGHV1-2 Gene

SuperPathways for IGHV1-2 Gene

No Data Available

Interacting Proteins for IGHV1-2 Gene

Gene Ontology (GO) - Biological Process for IGHV1-2 Gene

None

No data available for Pathways by source for IGHV1-2 Gene

Transcripts for IGHV1-2 Gene

mRNA/cDNA for IGHV1-2 Gene

(7) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for IGHV1-2 Gene

No ASD Table

Relevant External Links for IGHV1-2 Gene

GeneLoc Exon Structure for
IGHV1-2
ECgene alternative splicing isoforms for
IGHV1-2

Expression for IGHV1-2 Gene

mRNA expression in normal human tissues for IGHV1-2 Gene

mRNA differential expression in normal tissues according to GTEx for IGHV1-2 Gene

This gene is overexpressed in Spleen (11.4), Colon - Transverse (6.9), Small Intestine - Terminal Ileum (6.1), and Whole Blood (4.3).

Integrated Proteomics: protein expression from for IGHV1-2 Gene

genes like me logo Genes that share expressions with IGHV1-2: view

Orthologs for IGHV1-2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for IGHV1-2 Gene

Organism Taxonomy Gene Similarity Type Details
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 33 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 36 (a)
ManyToMany
chicken
(Gallus gallus)
Aves -- 37
  • 27 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 53 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ighv4-6 37
  • 41 (a)
ManyToMany
Species with no ortholog for IGHV1-2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for IGHV1-2 Gene

ENSEMBL:
Gene Tree for IGHV1-2 (if available)
TreeFam:
Gene Tree for IGHV1-2 (if available)

Paralogs for IGHV1-2 Gene

genes like me logo Genes that share paralogs with IGHV1-2: view

Variants for IGHV1-2 Gene

Relevant External Links for IGHV1-2 Gene

HapMap Linkage Disequilibrium report
IGHV1-2

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for IGHV1-2 Gene

Disorders for IGHV1-2 Gene

genes like me logo Genes that share disorders with IGHV1-2: view

No data available for UniProtKB/Swiss-Prot for IGHV1-2 Gene

Publications for IGHV1-2 Gene

  1. Dispersed localization of D segments in the human immunoglobulin heavy-chain locus. (PMID: 2841108) Matsuda F. … Honjo T. (EMBO J. 1988) 3

Products for IGHV1-2 Gene

Sources for IGHV1-2 Gene

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