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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IGHG1 Gene

protein-coding   GIFtS: 53
GCID: GC14M106204

immunoglobulin heavy constant gamma 1 (G1m marker)
 Explore 21 diseases affiliated with
IGHG1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for IGHG1    

Aliases
for IGHG1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Immunoglobulin Heavy Constant Gamma 1 (G1m Marker)1 2

External Ids:    HGNC: 55251   Entrez Gene: 35002   Ensembl: ENSG000002118967   OMIM: 1471005   UniProtKB: P018573   

Export aliases for IGHG1 gene to outside databases

Previous GC identifers: GC14M103243 GC14U900161 GC14M104063 GC14M104065 GC14M105244 GC14M105278 GC14M105275 GC14M086340


Summaries
for IGHG1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Gene Wiki entry for IGHG1


Genomic Views
for IGHG1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for IGHG1
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for IGHG1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGHG1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.33   Ensembl cytogenetic band:  14q32.33   HGNC cytogenetic band: 14q32.33

IGHG1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IGHG1 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M106204:  view genomic region     (about GC identifiers)

Start:
 106,202,680 bp from pter      End:
 106,209,408 bp from pter
Size:
 6,729 bases      Orientation:
 minus strand

Proteins
for IGHG1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: IGHG1_HUMAN, P01857 (See protein sequence)
Recommended Name: Ig gamma-1 chain C region  
Size: 330 amino acids; 36106 Da
Subcellular location: Secreted
Miscellaneous: Nie has the G1M(17) allotypic marker, 97-K, and the G1M(1) markers, 239-D and 241-L. KOL and EU
sequences have the G1M(3) marker and the G1M (non-1) markers
Sequence caution: Sequence=AAC82527.1; Type=Erroneous initiation;
6/95 PDB 3D structures from and Proteopedia for IGHG1 (see all 95):
1AJ7 (3D)        1AQK (3D)        1BEY (3D)        1D5B (3D)        1D5I (3D)        1D6V (3D)    

Explore the universe of human proteins at neXtProt for IGHG1: NX_P01857

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P01857

    • IGHG1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).


    ENSEMBL proteins: 
     ENSP00000374990   ENSP00000374991   ENSP00000374984  
    Reactome Protein details: P01857
    Human Recombinant Protein Products: 
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    Novus Biologicals IGHG1 Protein
    Novus Biologicals IGHG1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--
    GO:0005624membrane fraction ----
    GO:0016020membrane NAS--


    IGHG1 for ontologies           About GeneDecksing



    IGHG1 Antibody Products: 
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    Novus Biologicals IGHG1 Antibodies
    Abcam antibodies for IGHG1 
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    ThermoFisher Antibodies for IGHG1

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    GenScript Custom Assay Services for IGHG1
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs and CLIAs at Uscn

    Protein Domains /
    Families
    for IGHG1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IGHG1 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR013783 Ig-like_fold
     IPR003597 Ig_C1-set
     IPR007110 Ig-like_dom
     IPR003006 Ig/MHC_CS

    Graphical View of Domain Structure for InterPro Entry P01857

    ProtoNet protein and cluster: P01857

    1 Blocks protein family: IPB003597 Immunoglobulin C-type


    Function
    for IGHG1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
         Genatlas biochemistry entry for IGHG1:
    immunoglobulin,gamma 1 (Gm marker)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IGHG1
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    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
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    Browse OriGene siRNA
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for IGHG1

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003823antigen binding TAS6287432
    GO:0005515protein binding IPI11567028


    IGHG1 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for IGHG1: Ighg1tm1Ksho Ighg1tm3Cgn Ighg1tm2Cgn Ighg1tm1.1Ksho Ighg1tm4Cgn
         6 MGI mutant phenotypes (inferred from 7 alleles) (MGI details for Ighg1):
     cellular  hematopoietic system  immune system  mortality/aging  no phenotypic analysis 
     tumorigenesis 

    IGHG1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for IGHG1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cleavage of Alpha-1-Microglobulin
    		Classical antibody-mediated complement activation0.74
    		Initial triggering of complement0.60
    		Creation of C4 and C2 activators0.70
    		Role of phospholipids in phagocytosis0.53
    		Sequestering and phosphorylation Fc gamma receptors in the lipid rafts0.66
    		Complement cascade0.47
    		FCGR activation0.65
    2Regulation of actin dynamics for phagocytic cup formation
    		Regulation of actin dynamics for phagocytic cup formation1.00
    		Fcgamma receptor (FCGR) dependent phagocytosis0.80
    		Role of myosins in phagosome formation0.80
    3Immune response_Classical complement pathway
    		Immune response_Classical complement pathway1.00
    		Immune response Classic complement pathway0.98
    4Immune response_IL-4 signaling pathway
    		Immune response_IL-4 signaling pathway1.00
    		Immune response IL-4 signaling pathway0.98
    5Immune System
    		Immune System1.00
    		Innate Immune System0.46

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    3 EMD Millipore Pathways for IGHG1
        Immune response Classic complement pathway
    Immune response CD16 signaling in NK cells
    Immune response IL-4 signaling pathway


    3 GeneGo (Thomson Reuters) Pathways for IGHG1
        Immune response IL-4 signaling pathway
    Immune response CD16 signaling in NK cells
    Immune response Classical complement pathway

    1 BioSystems Pathway for IGHG1 
        IL4-mediated signaling events

    5/12        Reactome Pathways for IGHG1 (see all 12)
        Role of myosins in phagosome formation
    FCGR activation
    Fcgamma receptor (FCGR) dependent phagocytosis
    Classical antibody-mediated complement activation
    Regulation of actin dynamics for phagocytic cup formation



    IGHG1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGHG1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/120 Interacting proteins for IGHG1 (P018571, 2, 3 ENSP000003749904) via UniProtKB, MINT, STRING, and/or I2D (see all 120)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FCGR2BP319941, 3, ENSP000003514974EBI-356114,EBI-724784 I2D: score=1 STRING: ENSP00000351497
    IKBKGQ9Y6K92, 3MINT-48194 I2D: score=2 
    IGKCP018342, 3, ENSP000003747774MINT-24896 MINT-25051 I2D: score=3 STRING: ENSP00000374777
    TRAF1Q130772, 3, ENSP000003629944MINT-49522 I2D: score=2 STRING: ENSP00000362994
    IGLC1P0CG043, ENSP000003748554I2D: score=2 STRING: ENSP00000374855
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response NAS--
    GO:0006956complement activation TAS--
    GO:0006958complement activation, classical pathway TAS--
    GO:0045087innate immune response TAS--


    IGHG1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for IGHG1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IGHG1

    10/25 DrugBank Compounds for IGHG1 (see all 25)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL-- --target--10592235
    (2-AMINO-3-PHENYL-BICYCLO[2.2.1]HEPT-2-YL)-PHENYL-METHANONE-- --target--10592235
    2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID-- --target--10592235
    3-(10-METHYL-ANTHRACEN-9-YL)-PROPIONIC ACID-- --target--10592235
    3-{[(9-CYANO-9,10-DIHYDRO-10-METHYLACRIDIN-9-YL)CARBONYL]AMINO}PROPANOIC ACID-- --target--10592235
    4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID-- --target--10592235
    4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE-- --target--10592235
    5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID-- --target--10592235
    5-BETA-ANDROSTANE-3,17-DIONE-- --target--10592235
    6-{4-[HYDROXY-(4-NITRO-PHENOXY)-PHOSPHORYL]-BUTYRYLAMINO}-HEXANOIC ACID-- --target--10592235

    Search CenterWatch for drugs/clinical trials and news about IGHG1 

    Transcripts
    for IGHG1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    Unigene Cluster for IGHG1:

    Immunoglobulin heavy constant gamma 1 (G1m marker)
    Hs.510635  [show with all ESTs]
    Unigene Representative Sequence: AK090461
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000390548(uc001yse.3) ENST00000390549 ENST00000390542

    miRNA
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    Inhib. RNA
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    Browse OriGene siRNA
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    Clone
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    Primer
    Products:            		Browse OriGene genome-wide validated SYBR primer pairs
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    Additional cDNA sequence: 

    AB004303.1 AB006837.1 AB006839.1 AB006840.1 AB012909.1 AB022650.1 AB022652.1 AB022655.1 
    AB027433.1 AB027435.2 AB027437.2 AB027439.1 AB027441.1 AB027443.1 AB027445.1 AB027447.1 
    AB027766.1 AB030639.1 AB063667.1 AB063677.1 AB063678.1 AB063679.1 AB063680.1 AB063686.1 
    AB063687.1 AB063697.1 AB063703.1 AB063719.1 AB063724.1 AB063750.1 AB063756.1 AB063801.1 
    AB063809.1 AB063849.1 AB063864.1 AB063872.1 AB063881.1 AB063891.1 AB063907.1 AB063912.1 
    AB063922.1 AB066901.1 AB066908.1 AB066925.1 AB066926.1 AB066940.1 AB066944.1 AB066951.1 
    AB066952.1 AB066955.1 AB066956.1 AB066959.1 AB066970.1 AB066990.1 AB066996.1 AB067004.1 
    AB067014.1 AB067020.1 AB067047.1 AB067048.1 AB067059.1 AB067072.1 AB067107.1 AB067119.1 
    AB067126.1 AB067141.1 AB067172.1 AB067173.1 AB067178.1 AB067181.1 AB067192.1 AB067256.1 
    AB067267.1 AB067281.1 AB067287.1 AB067291.1 AB067301.1 AB067307.1 AB067308.1 AB067314.1 
    AB067335.1 AB067336.1 AB067338.1 AB067339.1 AB067340.1 AB067341.1 AB067342.1 AB067343.1 
    AB067344.1 AB067347.1 AB067349.1 AB067351.1 AB067353.1 AB067354.1 AB067355.1 AB067357.1 
    AB067358.1 AB067361.1 AB067362.1 AB067363.1 AB067364.1 AB067365.1 AB067366.1 AB067368.1 
    AB067369.1 AB067370.1 AB067373.1 AB067374.1 AB067376.1 AB067385.1 AB067386.1 AB067390.1 
    AB067393.1 AB084083.1 AB084084.1 AB087877.1 AB095272.1 AB095276.1 AB110646.1 AB159728.1 
    AB245095.1 AB266513.1 AB274406.1 AB274408.1 AB274410.1 AB274412.1 AB288084.1 AB289325.1 
    AB289326.1 AB289327.1 AB363079.1 AB363083.1 AB363106.1 AB363142.1 AB363143.1 AB363146.1 
    AB363155.1 AB363161.1 AB363196.1 AB363237.1 AB373613.1 AB373634.1 AB374357.1 AB453230.1 
    AB453231.1 AB453232.1 AB453233.1 AB585999.1 AB608263.1 AB608264.1 AB608265.1 AF001789.1 
    AF006517.1 AF006518.1 AF006521.1 AF006523.1 AF006526.1 AF006527.1 AF006528.1 AF013615.1 
    AF013616.1 AF013619.1 AF013620.1 AF013621.1 AF013622.1 AF015135.1 AF015136.1 AF015137.1 
    AF015138.1 AF015139.1 AF015140.1 AF015141.1 AF015142.1 AF015144.1 AF015146.1 AF017457.1 
    AF019639.1 AF019640.1 AF019641.1 AF019642.1 AF021940.1 AF021941.1 AF021947.1 AF021969.1 
    AF021978.1 AF021985.1 AF021987.1 AF021988.1 AF021994.1 AF021997.1 AF022003.1 AF022007.1 
    AF027159.2 AF028092.1 AF028093.1 AF028094.1 AF028095.1 AF028096.1 AF028097.1 AF028098.1 
    AF028102.1 AF028111.1 AF028112.1 AF028114.1 AF028115.1 AF028119.1 AF028120.1 AF028121.1 
    AF032352.1 AF035019.1 AF035020.1 AF035030.1 AF035039.1 AF035040.1 AF051100.1 AF052386.1 
    AF062092.1 AF062110.1 AF062114.1 AF062123.1 AF062134.1 AF062135.1 AF062137.1 AF062139.1 
    AF062140.1 AF062142.1 AF062143.1 AF062151.1 AF062159.1 AF062165.1 AF062170.1 AF062178.1 
    AF062179.1 AF062194.1 AF062195.1 AF062197.1 AF062200.1 AF062203.1 AF062207.1 AF062213.1 
    AF062219.1 AF062220.1 AF062221.1 AF062226.1 AF062230.1 AF062245.1 AF062254.1 AF062256.1 
    AF062257.1 AF062258.1 AF062262.1 AF062264.1 AF062267.1 AF062271.1 AF062272.1 AF062273.1 
    AF062284.1 AF064881.1 AF064882.1 AF064883.1 AF064884.1 AF067121.1 AF069906.1 AF069907.1 
    AF078551.1 AF082193.1 AF082200.1 AF090356.1 AF098366.1 AF099198.1 AF103028.1 AF103030.1 
    AF103033.2 AF103039.1 AF103050.1 AF103052.1 AF103064.1 AF103067.1 AF103070.1 AF103079.1 
    AF103086.1 AF103096.1 AF103114.1 AF103117.1 AF103119.1 AF103120.1 AF103122.1 AF103124.1 
    AF103125.1 AF103129.1 AF103131.1 AF103153.1 AF103154.1 AF103160.1 AF103163.1 AF103167.1 
    AF103168.1 AF103174.2 AF103175.1 AF103185.1 AF103186.1 AF103189.1 AF103190.1 AF103191.1 
    AF103192.1 AF103199.1 AF103203.1 AF103205.1 AF103206.1 AF103211.1 AF103219.1 AF103223.1 
    AF103225.1 AF103226.1 AF103237.1 AF103238.1 AF103247.1 AF103248.1 AF103253.1 AF103261.1 
    AF103263.1 AF103264.1 AF103265.1 AF103272.1 AF103281.1 AF103282.1 AF103288.1 AF103308.1 
    AF103311.1 AF103343.2 AF103345.1 AF103348.1 AF103363.1 AF103768.1 AF103769.1 AF103770.1 
    AF103795.1 AF107236.1 AF110149.1 AF110481.1 AF110483.1 AF115113.1 AF115128.1 AF115129.1 
    AF123353.1 AF123362.1 AF129749.1 AF146401.1 AF150959.1 AF163305.1 AF163307.1 AF165105.1 
    AF165109.1 AF165112.1 AF166264.1 AF174005.1 AF174006.1 AF174009.1 AF174011.1 AF174013.1 
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    JN158132.1 JN158133.1 JN158134.1 JN158136.1 JN158137.1 JN158138.1 JN158139.1 JN158140.1 
    JN158141.1 JN158142.1 JN158143.1 JN158144.1 JN158145.1 JN158146.1 JN158147.1 JN158148.1 
    JN158149.1 JN158151.1 JN158152.1 JN158153.1 JN158154.1 JN158155.1 JN158156.1 JN158157.1 
    JN158158.1 JN158160.1 JN158161.1 JN158162.1 JN158163.1 JN158164.1 JN158165.1 JN158166.1 
    JN158167.1 JN158168.1 JN158170.1 JN158171.1 JN158173.1 JN158175.1 JN158176.1 JN158177.1 
    JN158178.1 JN158179.1 JN158180.1 JN158181.1 JN158182.1 JN158183.1 JN158184.1 JN158185.1 
    JN158186.1 JN158187.1 JN158188.1 JN158189.1 JN158190.1 JN158191.1 JN158192.1 JN158193.1 
    JN158194.1 JN158196.1 JN158197.1 JN158198.1 JN158199.1 JN158200.1 JN158201.1 JN158202.1 
    JN158203.1 JN158204.1 JN158205.1 JN158206.1 JN158207.1 JN158208.1 JN158210.1 JN158211.1 
    JN158212.1 JN158213.1 JN158214.1 JN158215.1 JN158216.1 JN158217.1 JN158218.1 JN158219.1 
    JN158221.1 JN158222.1 JN158223.1 JN158224.1 JN158225.1 JN158226.1 JN158227.1 JN158228.1 
    JN158232.1 JN158233.1 JN158234.1 JN158235.1 JN158236.1 JN158237.1 JN158239.1 JN158242.1 
    JN158244.1 JN158247.1 JN158248.1 JN158250.1 JN158251.1 JN158253.1 JN158254.1 JN158255.1 
    JN158256.1 JN158257.1 JN158258.1 JN158259.1 JN158260.1 JN158261.1 JN158262.1 JN158263.1 
    JN158264.1 JN158265.1 JN158267.1 JN158268.1 JN158269.1 JN158270.1 JN158271.1 JN158272.1 
    JN158273.1 JN158274.1 JN158275.1 JN158276.1 JN158277.1 JN158278.1 JN158279.1 JN158280.1 
    JN158281.1 JN158282.1 JN158283.1 JN158284.1 JN158286.1 JN158287.1 JN158288.1 JN158289.1 
    JN158290.1 JN158291.1 JN158292.1 JN158293.1 JN158294.1 JN158295.1 JN158296.1 JN158297.1 
    JN158298.1 JN158299.1 JN158300.1 JN158301.1 JN158303.1 JN158304.1 JN158305.1 JN158306.1 
    JN158308.1 JN158310.1 JN158311.1 JN158312.1 JN158313.1 JN158315.1 JN158316.1 JN158317.1 
    JN158318.1 JN158319.1 JN158320.1 JN158322.1 JN158324.1 JN158325.1 JN158326.1 JN158328.1 
    JN158329.1 JN158330.1 JN158332.1 JN158333.1 JN158334.1 JN158335.1 JN158336.1 JN158337.1 
    JN158339.1 JN158340.1 JN158341.1 JN158342.1 JN158343.1 JN158344.1 JN158345.1 JN158346.1 
    JN158347.1 JN158348.1 JN158349.1 JN158350.1 JN158351.1 JN158352.1 JN158353.1 JN158354.1 
    JN158355.1 JN158356.1 JN158357.1 JN158359.1 JN158360.1 JN158361.1 JN158362.1 JN158363.1 
    JN158365.1 JN158366.1 JN158367.1 JN158368.1 JN158369.1 JN158370.1 JN158372.1 JN158373.1 
    JN158374.1 JN158375.1 JN158376.1 JN158377.1 JN158378.1 JN158379.1 JN158380.1 JN158381.1 
    JN158382.1 JN158383.1 JN158384.1 JN158385.1 JN158386.1 JN158387.1 JN158388.1 JN158389.1 
    JN158390.1 JN158391.1 JN158392.1 JN158393.1 JN158394.1 JN158396.1 JN158397.1 JN158398.1 
    JN158399.1 JN158400.1 JN158402.1 JN158403.1 JN158404.1 JN158405.1 JN158406.1 JN158407.1 
    JN158408.1 JN158409.1 JN158410.1 JN158411.1 JN158412.1 JN158413.1 JN158414.1 JN158415.1 
    JN158416.1 JN158417.1 JN158418.1 JN158419.1 JN158420.1 JN158421.1 JN158422.1 JN158423.1 
    JN158424.1 JN158425.1 JN158426.1 JN158427.1 JN158428.1 JN158429.1 JN158430.1 JN158431.1 
    JN158432.1 JN158433.1 JN158434.1 JN158435.1 JN158436.1 JN158437.1 JN158438.1 JN158439.1 
    JN158440.1 JN158441.1 JN158442.1 JN158443.1 JN158445.1 JN158446.1 JN158447.1 JN158448.1 
    JN158451.1 JN158452.1 JN158453.1 JN158454.1 JN158455.1 JN158456.1 JN158457.1 JN158458.1 
    JN158461.1 JN158463.1 JN158464.1 JN158465.1 JN158466.1 JN158467.1 JN158468.1 JN158469.1 
    JN158470.1 JN158471.1 JN158472.1 JN158473.1 JN158475.1 JN158476.1 JN158477.1 JN158478.1 
    JN158479.1 JN158480.1 JN158481.1 JN158482.1 JN158484.1 JN158485.1 JN158486.1 JN158490.1 
    JN158492.1 JN158493.1 JN158496.1 JN158497.1 JN158500.1 JN158503.1 JN158504.1 JN158508.1 
    JN159340.1 JN159341.1 JN159344.1 JN159345.1 JN159346.1 JN159347.1 JN159348.1 JN159353.1 
    JN159356.1 JN159360.1 JN159361.1 JN159362.1 JN159363.1 JN159366.1 JN159367.1 JN159369.1 
    JN159372.1 JN159374.1 JN159376.1 JN159380.1 JN159382.1 JN159383.1 JN159384.1 JN159385.1 
    JN159389.1 JN159391.1 JN159394.1 JN159397.1 JN159398.1 JN159401.1 JN159403.1 JN159405.1 
    JN159408.1 JN159412.1 JN159413.1 JN159416.1 JN159424.1 JN159425.1 JN159427.1 JN159428.1 
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    JN376166.1 JN376167.1 JN376168.1 JN376169.1 JN376170.1 JN376174.1 JN376175.1 JN376179.1 
    JN376180.1 JN376181.1 JN376182.1 JN376183.1 JN376190.1 JN376191.1 JN376192.1 JN376200.1 
    JN376208.1 JN376209.1 JN376210.1 JN376211.1 JN376212.1 JN376213.1 JN376237.1 JN376238.1 
    JN376239.1 JN376240.1 JN376241.1 JN376242.1 JN376243.1 JN376244.1 JN376245.1 JN376246.1 
    JN376247.1 JN376248.1 JN376249.1 JN376250.1 JN376252.1 JN376253.1 JN376259.1 JN376260.1 
    JN376261.1 JN376272.1 JN376277.1 JN376278.1 JN376279.1 JN376280.1 JN376281.1 JN376282.1 
    JN376288.1 JN376291.1 JN376292.1 JN376294.1 JN376295.1 JN376296.1 JN376297.1 JN376298.1 
    JN376299.1 JN376300.1 JN376307.1 JN376309.1 JN376356.1 JN376397.1 JN376398.1 JN376399.1 
    JN376400.1 JN376401.1 JN376402.1 JN376403.1 JN376404.1 JN376405.1 JN376406.1 JN376407.1 
    JN376408.1 JN376409.1 JN376417.1 JN376422.1 JN376423.1 JN376424.1 JN376433.1 JN376434.1 
    JN376439.1 JN376440.1 JN376442.1 JN376446.1 JN376452.1 JN376453.1 JN376454.1 JN376455.1 
    JN376456.1 JN376457.1 JN376458.1 JN376459.1 JN376460.1 JN376464.1 JN376465.1 JN376469.1 
    JN376470.1 JN376471.1 JN376472.1 JN376473.1 JN376474.1 JN376475.1 JN376476.1 JN376477.1 
    JN376478.1 JN376479.1 JN376480.1 JN376481.1 JN376483.1 JN376487.1 JN376488.1 JN376493.1 
    JN376494.1 JN376495.1 JN376496.1 JN376497.1 JN376498.1 JN376499.1 JN376502.1 JN376503.1 
    JN376504.1 JN376507.1 JN376526.1 JN376527.1 JN376608.1 JN376620.1 JN376621.1 JN376625.1 
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    JN376640.1 JN376641.1 JN376647.1 JN376653.1 JN376655.1 JN376657.1 JN376658.1 JN376659.1 
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    JQ304251.1 JQ304253.1 JQ666008.1 JQ837831.1 JQ917464.1 JX027380.1 JX027384.1 JX027399.1 
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    JX649946.1 L01278.1 L01410.1 L01412.1 L02258.1 L02260.1 L03139.1 L03141.1 
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    L23555.1 L23558.1 L23559.1 L23568.1 L23569.1 L23570.1 L23930.1 L23933.1 
    L25294.1 L26533.1 L26535.1 L26892.1 L26906.1 L28053.1 L29117.1 L29118.1 
    L29119.1 L29120.1 L33037.1 L38560.1 L38564.1 L41062.1 L48241.1 M18510.1 
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    M71230.1 M71233.1 M71234.1 M84507.1 M87789.1 M88316.1 M97802.1 M97919.1 
    M97921.1 M98324.1 M98867.1 M98868.1 M99372.1 M99598.1 M99609.1 S42403.1 
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    S71250.1 S73138.1 S74498.1 S74500.1 S74501.1 S74502.1 S74639.1 S74640.1 
    S74642.1 S74643.1 S75894.1 S76902.1 U00514.1 U00519.1 U00526.1 U00528.1 
    U00529.1 U00531.1 U00533.1 U00535.1 U00542.1 U00544.1 U00548.1 U00551.1 
    U00554.1 U00558.1 U00562.1 U00565.1 U00568.1 U00587.1 U05889.1 U05890.1 
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    U32489.1 U32491.1 U32599.1 U32610.1 U32612.1 U32951.1 U32952.1 U32961.1 
    U32962.1 U32963.1 U36535.1 U36542.1 U36543.1 U36544.1 U36545.1 U36546.1 
    U36547.1 U36548.1 U36549.1 U36550.1 U36551.1 U36552.1 U36553.1 U36554.1 
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    U38333.1 U43755.1 U43758.1 U43760.1 U43762.1 U50344.1 U51549.1 U63211.1 
    U64466.1 U64472.1 U64497.1 U66189.1 U70233.1 U71104.1 U79584.1 U81383.1 
    U82948.1 U82950.1 U82961.1 U85239.1 U86522.1 U86785.1 U86787.1 U86797.1 
    U92452.1 U96289.1 X17115.1 X17676.1 X52847.1 X52893.1 X55344.1 X55345.1 
    X56592.1 X57086.1 X57414.1 X57415.1 X58529.1 X59702.1 X61012.1 X61016.1 
    X61017.1 X61020.1 X61651.1 X64155.1 X64236.1 X64242.1 X65883.1 X65885.1 
    X65887.1 X65888.1 X65891.1 X65892.1 X65893.1 X65916.1 X65917.1 X65918.1 
    X65920.1 X67292.1 X67301.1 X67879.1 X67880.1 X67881.1 X67882.1 X67883.1 
    X67884.1 X67885.1 X67886.1 X67887.1 X67888.1 X67889.1 X67890.1 X67891.1 
    X67892.1 X67893.1 X67894.1 X67895.1 X67896.1 X67897.1 X67898.1 X67900.1 
    X69692.1 X75021.1 X75388.1 X79158.1 X79159.1 X79162.1 X79164.1 X79165.1 
    X79166.1 X79168.1 X79177.1 X79178.1 X79180.1 X79181.1 X81695.1 X81696.1 
    X84369.1 X84370.1 X87437.1 X87440.1 X92990.1 X92995.1 X92998.1 X93001.1 
    X93003.1 X94007.1 X94008.1 X94009.1 X94010.1 X94011.1 X94012.1 X94013.1 
    X94014.1 X94019.1 X94033.1 X94034.1 X94035.1 X94036.1 X94040.1 X94043.1 
    X94049.1 X94056.1 X94058.1 X94065.1 X94066.1 X94070.1 X94072.1 X94074.1 
    X97483.1 X98213.1 X98214.1 X98215.1 X98901.1 X98903.1 X98932.1 X98944.1 
    X98950.1 Y07816.1 Y08143.1 Y08144.1 Y08177.1 Y08178.1 Y08179.1 Y08183.1 
    Y08186.1 Y08303.1 Y08732.1 Y11326.1 Y14735.1 Y14737.1 Y14939.1 Y14943.1 
    Y14944.1 Y17142.1 Y17929.1 Y17957.2 Z11935.1 Z11952.1 Z11956.1 Z14158.1 
    Z14159.1 Z14160.1 Z14161.1 Z14162.1 Z14163.1 Z14164.1 Z14182.1 Z14183.1 
    Z14184.1 Z14185.1 Z14186.1 Z14187.1 Z14188.1 Z14194.1 Z14196.1 Z14207.1 
    Z14208.1 Z14209.1 Z14210.1 Z14211.1 Z14213.1 Z14220.1 Z14223.1 Z14248.1 
    Z15084.1 Z15110.1 Z18316.1 Z18320.1 Z18846.1 Z26827.1 Z26828.1 Z26831.1 
    Z26834.1 Z26835.1 Z26836.1 Z26837.1 Z26838.1 Z30544.1 Z30546.1 Z30548.1 
    Z30551.1 Z30556.1 Z30560.1 Z30563.1 Z30574.1 Z30594.1 Z30597.1 Z30672.1 
    Z33400.1 Z35120.1 Z36889.1 Z37152.1 Z46270.1 Z46272.1 Z46274.1 Z46276.1 
    Z46278.1 Z46279.1 Z46280.1 Z46281.1 Z46286.1 Z46290.1 Z46348.1 Z46771.1 
    Z46849.1 Z46855.1 Z47215.1 Z47221.1 Z47223.1 Z47236.1 Z47274.1 Z47275.1 
    Z47276.1 Z47277.1 Z49140.1 Z70256.1 Z70257.1 Z70635.1 Z70659.1 Z74668.1 
    Z75363.1 Z75372.1 Z75375.1 Z75386.1 Z75390.1 Z75396.1 Z75402.1 Z75404.1 
    Z75405.1 Z75406.1 Z80845.1 Z80847.1 Z80848.1 Z97032.1 Z98717.1 Z98718.1 
    Z98719.1 Z98722.1 Z98724.1 Z98726.1 Z98727.1 Z98728.1 Z98729.1 Z98730.1 
    Z98740.1 

    24/2691 DOTS entries (see all 2691):

    DT.100661637  DT.95368001  DT.100044050  DT.95281261  DT.100849604  DT.121509142  DT.96086462  DT.100046750 
    DT.91691002  DT.101985762  DT.121509392  DT.100684338  DT.100758330  DT.121505891  DT.100040735  DT.100044342 
    DT.100684353  DT.121508857  DT.91965015  DT.100046308  DT.100869699  DT.92036092  DT.92048405  DT.100837541 

    24/413 AceView cDNA sequences (see all 413):

    AI983792 CR615089 AI707611 CA447627 CR625295 BX161420 CR612308 CR611016 
    AI690594 CR612969 CR595242 BU632930 CA426198 CR607277 CR592732 BX248278 
    CR620071 CR626540 CR602293 CR600209 T29779 BU730880 AW516022 CR608756 

    GeneLoc Exon Structure


    Expression
    for IGHG1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IGHG1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GAAATAAAGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See IGHG1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IGHG1

    SOURCE GeneReport for Unigene cluster: Hs.510635
        SABiosciences Custom PCR Arrays for IGHG1
    Primer
    Products:    		Browse OriGene genome-wide validated SYBR primer pairs
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat IGHG1
    Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGHG1
    Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGHG1
    In Situ
    Assay Products:     
         		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for IGHG1

    Orthologs
    for IGHG1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for IGHG1 gene from 2/5 species (see all 5)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    		 --
    		 32(a)
    17(a)
    		 1 ↔ many
    possible ortholog
    		 GL343491.1(517133-525212)
    GL343491.1(485127-498368)
    zebrafish
    (Danio rerio)    		 Actinopterygii ighd6
    ighz6
    		 immunoglobulin heavy constant zeta
    		 6(a)
    17(a)
    		 many ↔ many
    many ↔ many
    		 3(34034542-34046885)
    3(34079980-34083059)


    ENSEMBL Gene Tree for IGHG1 (if available)
    TreeFam Gene Tree for IGHG1 (if available) 

    Paralogs
    for IGHG1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IGHG1 gene
    IGHG22  IGHE2  IGHG32  IGHM2  IGHA12  IGHG42  IGHA22  
    18/33 SIMAP similar genes for IGHG1 using alignment to 1 protein entry:     IGHG1_HUMAN(see all similar genes):
    DKFZp686C11235    DKFZp686G11190    DKFZp686H20196    DKFZp686I15196    DKFZp686K03196    DKFZp686N02209
    DKFZp686O01196    DKFZp686P15220    VHCH1    DKFZp686C15213    DKFZp686E23209    DKFZp686I04196
    DKFZp686M24218    IGHG2    IGHG4    DKFZp686I15212    FLJ00385    IGHG3

    IGHG1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for IGHG1
    PGOHUM00000250115 PGOHUM00000256741