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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IGHEP2 Gene

pseudogene   GIFtS: 15
GCID: GC09P005381

immunoglobulin heavy constant epsilon P2 (pseudogene)

(Previous names: immunoglobulin heavy constant epsilon P2, immunoglobulin...)
  Search for IGHEP2
in
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Biological research products
for IGHEP2    

Aliases
for IGHEP2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Immunoglobulin Heavy Constant Epsilon P2 (Pseudogene)1 2
Immunoglobulin Heavy Constant Epsilon P21
Immunoglobulin Heavy Constant Epsilon P2 Pseudogene1
IGHE5

External Ids:    HGNC: 55241   Entrez Gene: 34992   Ensembl: ENSG000002540177   OMIM: 1471805   

Export aliases for IGHEP2 gene to outside databases

Previous GC identifers: GC09U990046 GC09P005104 GC09P005107 GC09P005115 GC09P005125 GC09P005135 GC09P005146 GC09P005165 GC09P005185 GC09P005195 GC09P005218 GC09P005240 GC09P005261 GC09P005284 GC09P005309 GC09P005334 GC09P005357


Summaries
for IGHEP2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for IGHEP2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
 Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for IGHEP2
         Other transcription factors

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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGHEP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p24.1   Ensembl cytogenetic band:  9p24.1   HGNC cytogenetic band: 9p24.1

IGHEP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IGHEP2 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P005381:  view genomic region     (about GC identifiers)

Start:
 5,113,452 bp from pter      End:
 5,114,909 bp from pter
Size:
 1,458 bases      Orientation:
 plus strand

Proteins
for IGHEP2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB: --

Protein Domains /
Families
for IGHEP2 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
   --

Function
for IGHEP2 gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
Function Summary:
     Genatlas biochemistry entry for IGHEP2:
immunoglobulin,epsilon,pseudogene 2 (C epsilon 3)

miRNA
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Inhib. RNA
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Gene Editing
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Clone
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Cell Line
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In Situ Assay
Products:   
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Pathways & Interactions
for IGHEP2 gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IGHEP2

Drugs & Compounds
for IGHEP2 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for IGHEP2
Search CenterWatch for drugs/clinical trials and news about IGHEP2 

Transcripts
for IGHEP2 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000519308

miRNA
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Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:     		Browse for Gene Knock-down Tools from EMD Millipore
Browse OriGene 29mer shRNA kits
Browse OriGene siRNA
Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGHEP2
Clone
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Primer
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  Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGHEP2
  Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGHEP2

GeneLoc Exon Structure


Expression
for IGHEP2 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

IGHEP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)
About this image    SABiosciences Custom PCR Arrays for IGHEP2
Primer
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In Situ
Assay Products: 
 		Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for IGHEP2

Orthologs
for IGHEP2 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
   --

ENSEMBL Gene Tree for IGHEP2 (if available)
TreeFam Gene Tree for IGHEP2 (if available) 

Paralogs
for IGHEP2 gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

Genomic Variants
for IGHEP2 gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/99 NCBI SNPs in IGHEP2 are shown (see all 99)     About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance		Chr 9 posSequence#AA
Chg		TypeMore#Allele
freq		PopTotal
sample		More
----------
rs765809721,2
C,F,--5067601(+) CGACGG/TGGGTC 1 -- int12Minor allele frequency- T:0.09WA NA 238
rs736392641,2
C,--5067994(+) AGAAGA/GAGGAG 1 -- int12Minor allele frequency- G:0.05WA 120
rs169226381,2
C,F,H,--5068222(+) GCCGTC/GTCGGT 1 -- int19Minor allele frequency- G:0.02NA NS EA CSA WA 674
rs123757811,2
C--5068709(+) TGCATC/TTTGGC 1 -- int11Minor allele frequency- T:0.00NA 2
rs283703871,2
C,F,H--5068766(+) TTTTTT/CCCAGT 1 -- int16Minor allele frequency- C:0.01NS NA 1016
rs284072181,2
C,F,H,--5068860(+) GTAACA/GTATCA 1 -- int14Minor allele frequency- G:0.01NS NA 612
rs361000131,2
C--5069025(+) GATCAG/AACTGG 1 -- int13Minor allele frequency- A:0.17NA 6
rs117918761,2
C,H--5069035(+) GCCTAG/AAGTAG 1 -- int15Minor allele frequency- A:0.00NS EA NA 408
rs132889291,2
H--5069282(+) GCCCTC/GTGGCC 1 -- int14Minor allele frequency- G:0.00NS EA 408
rs1131030441,2
--5069548(+) CAGGTC/TGTGGA 1 -- int12Minor allele frequency- T:0.04CSA WA 120

HapMap Linkage Disequilibrium report for IGHEP2 (5113452 - 5114909 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for IGHEP2: --

SABiosciences Cancer Mutation PCR Assays
Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGHEP2
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Disorders / Diseases
for IGHEP2 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
IGHEP2 for disorders           About MalaCards

IGHEP2 for disorders           About GeneDecksing

OMIM gene information: 147180    OMIM disorders: --


Export disorders for IGHEP2 gene to outside databases

Publications
for IGHEP2 gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for IGHEP2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with IGHEP2)		    Utopia: connect your pdf to the dynamic
world of online information

  1. A processed human immunoglobulin epsilon gene has moved to chromosome 9. (PubMed id 6964396)1, 3 Battey J....Leder P. (1982)
  2. The sequence of a human immunoglobulin epsilon heavy chain constant region gene, and evidence for three non-allelic genes. (PubMed id 6327276)1 Ueda S.... Honjo T. (1982)

External Searches for IGHEP2 gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing IGHEP2 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 3499 HGNC: 5524 Ensembl:ENSG00000254017 euGenes: HUgn3499 ECgene: IGHEP2
H-InvDB: IGHEP2

Other Databases showing IGHEP2 gene

(According to HUGE)
About This Section
   --

Specialized Databases showing IGHEP2 gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for IGHEP2 Pharmacogenomics, SNPs, Pathways
IMGT entry for IGHEP2 The international ImMunoGeneTics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.

Intellectual Property
for IGHEP2 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for IGHEP2 gene:
Search GeneIP for patents involving IGHEP2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



Products
for IGHEP2 gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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Advanced Cell Diagnostics
About This Section

 
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