Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

IGFBPL1 Gene

protein-coding GIFtS: 44
GCID: GC09M038396

insulin-like growth factor binding protein-like 1

Explore 2 diseases affiliated with
IGFBPL1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Insulin-Like Growth Factor Binding Protein-Like 1¹ ²		IGFBP-RP4²
BA113O24.1¹		Insulin-Like Growth Factor Binding Protein Related Protein 4²
Insulin-Like Growth Factor-Binding-Related Protein 4² ³		Insulin-Like Growth Factor-Binding Protein-Like 1²
IGFBPRP4² ³		IGFBP-RP4²
IGFBP-Related Protein 10² ³

External Ids:	HGNC: 20081¹	Entrez Gene: 347252²	Ensembl: ENSG00000137142⁷	OMIM: 610413⁵	UniProtKB: Q8WX77³

Export aliases for IGFBPL1 gene to outside databases

Previous GC identifer: GC09M038399

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: IBPL1_HUMAN, Q8WX77

Function: IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the

growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface

receptors (By similarity). May be a putative tumor suppressor protein

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000009.11 NC_018920.1 NT_008413.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the IGFBPL1 gene promoter:
SRF AhR Egr-2 Nkx6-1 SRF (504 AA) FOXJ2 (long isoform) FOXJ2 Arnt
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: IGFBPL1 promoter sequence

Search SABiosciences Chromatin IP Primers for IGFBPL1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGFBPL1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p13.1 Ensembl cytogenetic band: 9p13.1 HGNC cytogenetic band: 9p12

IGFBPL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IGFBPL1 gene location

GeneLoc information about chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09M038396: view genomic region (about GC identifiers)

Start:	38,408,991 bp from pter	End:	38,424,444 bp from pter
Size:	15,454 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: IBPL1_HUMAN, Q8WX77 (See protein sequence)

Recommended Name: Insulin-like growth factor-binding protein-like 1 precursor

Size: 278 amino acids; 29005 Da

Subcellular location: Secreted

Explore the universe of human proteins at neXtProt for IGFBPL1: NX_Q8WX77

IGFBPL1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_001007564.1

ENSEMBL proteins:

ENSP00000366923

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: IGFBPL1 OriGene Protein Over-expression Lysate: IGFBPL1 OriGene Custom Protein Services for IGFBPL1
	GenScript Custom Purified and Recombinant Proteins Services for IGFBPL1
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for IGFBPL1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--

IGFBPL1 for ontologies About GeneDecksing

IGFBPL1 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	R&D Systems Antibodies for IGFBPL1 (IGFBP-L1)
	Browse OriGene Antibodies OriGene Custom Antibody Services for IGFBPL1
	GenScript Custom Superior Antibodies Services for IGFBPL1
	Novus Biologicals IGFBPL1 Antibody
	Search for Antibodies for IGFBPL1 at Abcam
	Uscn Antibodies for IGFBPL1
	Search ThermoFisher Antibodies for IGFBPL1

Assay Products for IGFBPL1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for IGFBPL1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for IGFBPL1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

IGFBPL1 for domains About GeneDecksing

5/7 InterPro domains/families (see all 7):

IPR003598 Ig_sub2

IPR002350 Prot_inh_Kazal

IPR013098 Ig_I-set

IPR013783 Ig-like_fold

IPR011390 IGFBP_rP_mac25

Graphical View of Domain Structure for InterPro Entry Q8WX77

ProtoNet protein and cluster: Q8WX77

2 Blocks protein families:

IPB003598 Immunoglobulin C-2 type

IPB013098 Immunoglobulin I-set

UniProtKB/Swiss-Prot: IBPL1_HUMAN, Q8WX77

Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain

Similarity: Contains 1 IGFBP N-terminal domain

Similarity: Contains 1 Kazal-like domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: IBPL1_HUMAN, Q8WX77

Function: IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the

growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface

receptors (By similarity). May be a putative tumor suppressor protein

Induction: Down-regulated in multiple tumors

miRNA Products:		OriGene 3'-UTR Clone: IGFBPL1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IGFBPL1
		6 QIAGEN miScript miRNA Assays for microRNAs that regulate IGFBPL1:
		hsa-miR-3163 hsa-miR-548d-3p hsa-miR-548am hsa-miR-548x hsa-miR-548n hsa-miR-548l
		SwitchGear 3'UTR luciferase reporter plasmid: IGFBPL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IGFBPL1 (see all 7) OriGene shRNA RFP: IGFBPL1 OriGene siRNA: IGFBPL1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGFBPL1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for IGFBPL1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IGFBPL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IGFBPL1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: IGFBPL1 (NM_001007563)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGFBPL1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IGFBPL1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for IGFBPL1
		Search LifeMap BioReagents cell lines for IGFBPL1

In Situ Assay
Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for IGFBPL1

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005520	insulin-like growth factor binding	IEA	--

IGFBPL1 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for IGFBPL1

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001558	regulation of cell growth	IEA	--

IGFBPL1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for IGFBPL1
Search CenterWatch for drugs/clinical trials and news about IGFBPL1 / IBPL1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for IGFBPL1 gene:

NM_001007563.2

Unigene Cluster for IGFBPL1:

Insulin-like growth factor binding protein-like 1

Hs.349705 [show with all ESTs]

Unigene Representative Sequence: AK131521

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000377694(uc004aba.3)

miRNA Products:		OriGene 3'-UTR Clone: IGFBPL1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IGFBPL1
		6 QIAGEN miScript miRNA Assays for microRNAs that regulate IGFBPL1:
		hsa-miR-3163 hsa-miR-548d-3p hsa-miR-548am hsa-miR-548x hsa-miR-548n hsa-miR-548l
		SwitchGear 3'UTR luciferase reporter plasmid: IGFBPL1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IGFBPL1 (see all 7) OriGene shRNA RFP: IGFBPL1 OriGene siRNA: IGFBPL1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGFBPL1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IGFBPL1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IGFBPL1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: IGFBPL1 (NM_001007563)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for IGFBPL1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IGFBPL1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IGFBPL1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat IGFBPL1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGFBPL1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGFBPL1

Additional cDNA sequence:

AK055716.1 AK131521.1

2 DOTS entries:

DT.102823294 DT.95153867

24/65 AceView cDNA sequences (see all 65):

AI424991 AA676754 AW089149 BE857533 CR595424 AI863108 AA598689 BQ899312

CR607939 Z41952 Z38240 AA620528 AI364268 BU956478 BX396150 BQ425046

BU680001 BE263253 BM674526 BM716864 AW090733 BX371609 BM701473 BQ681660

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for IGFBPL1 About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4	^	5	^	6a	·	6b
SP1:					-		-
SP2:													-
SP3:

ECgene alternative splicing isoforms for IGFBPL1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

IGFBPL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGTCACGAC

About this image

IGFBPL1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

5 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Blood Brain Barrier

Endothelial Cells

Blood Brain Barrier, Endothelium

Pancreas

Dorsal Pancreatic Bud

Immature Beta Progenitor Cells

Pancreas

Ventral Pancreatic Bud

Immature Beta Progenitor Cells

Pancreas

Adipose

Visceral White Adipose

Adipose

Head Mesenchyme

Frontonasal Process

Head Mesenchyme

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

See IGFBPL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IGFBPL1

SOURCE GeneReport for Unigene cluster: Hs.349705

UniProtKB/Swiss-Prot: IBPL1_HUMAN, Q8WX77

Tissue specificity: Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder

and lung

SABiosciences Custom PCR Arrays for IGFBPL1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IGFBPL1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat IGFBPL1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGFBPL1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGFBPL1

In Situ
Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for IGFBPL1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for IGFBPL1 gene from 1/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	IGFBPL1⁶	--	57(a)	1 ↔ 1	GL343201.1(3959804-4016112)

ENSEMBL Gene Tree for IGFBPL1 (if available)
TreeFam Gene Tree for IGFBPL1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for IGFBPL1 gene

KAZALD1² IGFBP7²

2 SIMAP similar genes for IGFBPL1 using alignment to 1 protein entry: IBPL1_HUMAN:

IGFBP7 KAZALD1

IGFBPL1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs4878811^1,2	C,F,H,	--	38408525(+)	`CCCACC/ATAAAA`	1	--	ds500¹		14		NS EA NA	2094
rs2038589^1,2	C,F,O,A,H,	--	38408592(+)	`ACACGC/TTGGGG`	1	--	ds500¹		30		NS EA NA WA CSA	2677
rs7853557^1,2	C,F,A,H,	--	38408688(+)	`TCTTAC/ATCTAG`	1	--	ds500¹		25		NS EA NA WA CSA	2354
rs7869227^1,2	C,F,A,H,	--	38408783(+)	`AGGGAC/TCTGTT`	1	--	ds500¹		14		NA WA CSA EA	380
rs183880973^1,2		--	38408789(+)	`CTGTTC/GAGGTC`	1	--	ds500¹		0	--	--	--	--
rs188112849^1,2		--	38408883(+)	`TAATAC/GGTCAT`	1	--	ds500¹		0	--	--	--	--
rs16935147^1,2	C,F,H,	--	38408920(+)	`TGACAC/TGAGCC`	1	--	ds500¹		19		NA NS EA CSA	2112
rs7854255^1,2	C,F,A,H,	--	38408948(+)	`ATGCCA/GTTCTG`	1	--	ds500¹		34		NA NS EA WA CSA	2924
rs7853944^1,2	C,F,A,H,	--	38408972(+)	`AGAGAG/ATAATT`	1	--	ds500¹		29		NA NS EA WA CSA	2492
rs7857013^1,2	C,F,A,H,	--	38409037(+)	`CAAATC/ACGTTT`	1	--	ut3¹ ese³		31		NA NS EA WA	3332

HapMap Linkage Disequilibrium report for IGFBPL1 (38408991 - 38424444 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for IGFBPL1
2 CNVs: 33092 47939

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGFBPL1

DNA2.0 Custom Variant and Variant Library Synthesis for IGFBPL1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

IGFBPL1 for disorders           About GeneDecksing

OMIM gene information: 610413    OMIM disorders: --

2 diseases for IGFBPL1:    About MalaCards

breast cancer prostatitis

Export disorders for IGFBPL1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for IGFBPL1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with IGFBPL1)

Utopia: connect your pdf to the dynamic
world of online information

Identification of a novel insulin-like growth factor binding protein gene homologue with tumor suppressor like properties. (PubMed id 15845387)^{1, 2} Cai Z.... Dedera D.A. (2005)
Epigenetic inactivation implies independent functions for insulin-like growth factor binding protein (IGFBP)-related protein 1 and the related IGFBPL1 in inhibiting breast cancer phenotypes. (PubMed id 17634530)¹ Smith P....Crook T. (2007)
Involvement of insulin-like growth factor-binding protein-related protein 1 in decidualization of human endometrial stromal cells. (PubMed id 17884839)¹ Kutsukake M....Tamura K. (2007)
DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)² Humphray S.J.... Dunham I. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 347252	HGNC: 20081	AceView: IGFBPL1	Ensembl:ENSG00000137142	euGenes: HUgn347252
ECgene: IGFBPL1	H-InvDB: IGFBPL1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for IGFBPL1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for IGFBPL1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for IGFBPL1 gene:
Search GeneIP for patents involving IGFBPL1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Antibodies for IGFBPL1 (IGFBP-L1)		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for IGFBPL1
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IGFBPL1		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IGFBPL1
	OriGene Protein Over-expression Lysate for IGFBPL1		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for IGFBPL1		OriGene 3'-UTR Clone for IGFBPL1
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IGFBPL1		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IGFBPL1
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for IGFBPL1		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for IGFBPL1		OriGene Custom Protein Services for IGFBPL1
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IGFBPL1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IGFBPL1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IGFBPL1
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IGFBPL1
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IGFBPL1
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IGFBPL1

	GenScript Custom Purified and Recombinant Proteins Services for IGFBPL1		GenScript cDNA clones with any tag delivered in your preferred vector for IGFBPL1
	GenScript Custom Assay Services for IGFBPL1		GenScript Custom Superior Antibodies Services for IGFBPL1
	GenScript Custom overexpressing Cell Line Services for IGFBPL1		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in IGFBPL1 promoter
	Search Chromatin IP Primers for IGFBPL1
	RT² qPCR Primer Assay in human, mouse, rat IGFBPL1
	Search GNC Networks for IGFBPL1
	SABiosciences Custom PCR Arrays for IGFBPL1

Search Tocris compounds for IGFBPL1

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	IGFBPL1 antibodies

	Search for Antibodies for IGFBPL1 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for IGFBPL1
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

IGFBPL1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for IGFBPL1

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for IGFBPL1

	SwitchGear 3'UTR luciferase reporter plasmids for IGFBPL1
	SwitchGear Promoter luciferase reporter plasmids for IGFBPL1

Search ThermoFisher Antibodies for IGFBPL1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IGFBPL1

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes IGFBPL1 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

IGFBPL1 Gene

insulin-like growth factor binding protein-like 1

Aliases
for IGFBPL1 gene

Summaries
for IGFBPL1 gene

Genomic Views
for IGFBPL1 gene

Proteins
for IGFBPL1 gene

Protein Domains /
Families
for IGFBPL1 gene

Function
for IGFBPL1 gene

Pathways & Interactions
for IGFBPL1 gene

Drugs & Compounds
for IGFBPL1 gene

Transcripts
for IGFBPL1 gene

Expression
for IGFBPL1 gene

Orthologs
for IGFBPL1 gene

Paralogs
for IGFBPL1 gene

Genomic Variants
for IGFBPL1 gene

Disorders / Diseases
for IGFBPL1 gene

Publications
for IGFBPL1 gene

External Searches for IGFBPL1 gene

Genome Databases showing IGFBPL1 gene

Other Databases showing IGFBPL1 gene

Specialized Databases showing IGFBPL1 gene

Intellectual Property
for IGFBPL1 gene

Products
for IGFBPL1 gene

View Random Gene

Advanced Search

Export list of displayed genes

IGFBPL1 Gene

insulin-like growth factor binding protein-like 1

Aliasesfor IGFBPL1 gene

Summariesfor IGFBPL1 gene

Genomic Viewsfor IGFBPL1 gene

Proteinsfor IGFBPL1 gene

Protein Domains /Familiesfor IGFBPL1 gene

Functionfor IGFBPL1 gene

Pathways & Interactionsfor IGFBPL1 gene

Drugs & Compoundsfor IGFBPL1 gene

Transcriptsfor IGFBPL1 gene

Expression for IGFBPL1 gene

Orthologsfor IGFBPL1 gene

Paralogsfor IGFBPL1 gene

Genomic Variantsfor IGFBPL1 gene

Disorders / Diseasesfor IGFBPL1 gene

Publicationsfor IGFBPL1 gene

External Searches for IGFBPL1 gene

Genome Databases showing IGFBPL1 gene

Other Databases showing IGFBPL1 gene

Specialized Databases showing IGFBPL1 gene

Intellectual Propertyfor IGFBPL1 gene

Productsfor IGFBPL1 gene

View Random Gene

Aliases
for IGFBPL1 gene

Summaries
for IGFBPL1 gene

Genomic Views
for IGFBPL1 gene

Proteins
for IGFBPL1 gene

Protein Domains /
Families
for IGFBPL1 gene

Function
for IGFBPL1 gene

Pathways & Interactions
for IGFBPL1 gene

Drugs & Compounds
for IGFBPL1 gene

Transcripts
for IGFBPL1 gene

Expression
for IGFBPL1 gene

Orthologs
for IGFBPL1 gene

Paralogs
for IGFBPL1 gene

Genomic Variants
for IGFBPL1 gene

Disorders / Diseases
for IGFBPL1 gene

Publications
for IGFBPL1 gene

Intellectual Property
for IGFBPL1 gene

Products
for IGFBPL1 gene