Aliases for IGFBP6 Gene
External Ids for IGFBP6 Gene
Previous GeneCards Identifiers for IGFBP6 Gene
GeneCards Summary for IGFBP6 Gene
IGFBP6 (Insulin-Like Growth Factor Binding Protein 6) is a Protein Coding gene. Diseases associated with IGFBP6 include exfoliative ichthyosis and insulin-like growth factor i. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Myometrial Relaxation and Contraction Pathways. GO annotations related to this gene include insulin-like growth factor I binding. An important paralog of this gene is IGFBP4.
UniProtKB/Swiss-Prot for IGFBP6 Gene
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors