Aliases for IGFBP5 Gene
External Ids for IGFBP5 Gene
GeneCards Summary for IGFBP5 Gene
IGFBP5 (Insulin-Like Growth Factor Binding Protein 5) is a Protein Coding gene. Diseases associated with IGFBP5 include insulin-like growth factor i and breast cancer. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Myometrial Relaxation and Contraction Pathways. GO annotations related to this gene include fibronectin binding and insulin-like growth factor I binding. An important paralog of this gene is IGFBP4.
UniProtKB/Swiss-Prot for IGFBP5 Gene
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors