Aliases for IGFBP2 Gene
External Ids for IGFBP2 Gene
Previous Symbols for IGFBP2 Gene
GeneCards Summary for IGFBP2 Gene
IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa) is a Protein Coding gene. Diseases associated with IGFBP2 include lung cancer and glioblastoma. Among its related pathways are Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein and Glucose / Energy Metabolism. GO annotations related to this gene include insulin-like growth factor I binding and insulin-like growth factor II binding. An important paralog of this gene is IGFBP4.
UniProtKB/Swiss-Prot for IGFBP2 Gene
Inhibits IGF-mediated growth and developmental rates. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.