Aliases for IGFALS Gene
Aliases for IGFALS Gene
External Ids for IGFALS Gene
- HGNC: 5468
- Entrez Gene: 3483
- Ensembl: ENSG00000099769
- OMIM: 601489
- UniProtKB: P35858
Previous GeneCards Identifiers for IGFALS Gene
- GC16M001857
- GC16M001780
- GC16M001840
Summaries for IGFALS Gene
-
The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
GeneCards Summary for IGFALS Gene
IGFALS (Insulin Like Growth Factor Binding Protein Acid Labile Subunit) is a Protein Coding gene. Diseases associated with IGFALS include Acid-Labile Subunit, Deficiency Of and 3-M Syndrome 1. Among its related pathways are Metabolism of proteins and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). GO annotations related to this gene include insulin-like growth factor binding. An important paralog of this gene is CHADL.
UniProtKB/Swiss-Prot for IGFALS Gene
-
Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGFALS Gene
Genomics for IGFALS Gene
Regulatory Elements for IGFALS Gene
Enhancers for IGFALS Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around IGFALS on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the IGFALS gene promoter:
Regulatory Element Products
Genomic Location for IGFALS Gene
- Chromosome:
- 16
- Start:
- 1,790,413 bp from pter
- End:
- 1,794,971 bp from pter
- Size:
- 4,559 bases
- Orientation:
- Minus strand
Genomic View for IGFALS Gene
Genes around IGFALS on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p13.3 by Ensembl
- 16p13.3 by Entrez Gene
- 16p13.3 by HGNC
IGFALS Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IGFALS Gene
Proteins for IGFALS Gene
-
Protein details for IGFALS Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P35858-ALS_HUMAN
- Recommended name:
- Insulin-like growth factor-binding protein complex acid labile subunit
- Protein Accession:
- P35858
- B4DZY8
- E9PGU3
Protein attributes for IGFALS Gene
- Size:
- 605 amino acids
- Molecular mass:
- 66035 Da
- Quaternary structure:
-
- Forms a ternary complex of about 140 to 150 kDa with IGF-I or IGF-II and IGFBP-3.
Protein Expression for IGFALS Gene
Post-translational modifications for IGFALS Gene
Other Protein References for IGFALS Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for IGFALS
-
Abcam antibodies for IGFALS
- Invitrogen Antibodies for IGFALS
- antibodies-online Antibodies for IGFALS: See all 47
- GeneTex IGFALS antibody for IGFALS
-
Santa Cruz Biotechnology (SCBT) Antibodies for IGFALS
Protein Products
-
OriGene Purified Proteins for IGFALS
- Search Origene for MassSpec and Protein Over-expression Lysates for IGFALS
- Origene Custom Protein Services for IGFALS
- antibodies-online Proteins for IGFALS: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for IGFALS
-
Abcam proteins for IGFALS
Assay Products
- antibodies-online Kits for IGFALS: See all 11
No data available for DME Specific Peptides for IGFALS Gene
Domains & Families for IGFALS Gene
Protein Domains for IGFALS Gene
Suggested Antigen Peptide Sequences for IGFALS Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families and UniProtKB/Swiss-Prot for IGFALS Gene
Function for IGFALS Gene
Molecular function for IGFALS Gene
- UniProtKB/Swiss-Prot Function:
- Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005520 | insulin-like growth factor binding | TAS | 1379671 |
Phenotypes for IGFALS Gene
- MGI mutant phenotypes for IGFALS:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for IGFALS:
Animal Models for IGFALS Gene
- MGI Knock Outs for IGFALS:
-
- Igfals tm1Yrb
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for IGFALS
-
-
ViGene Biosciences lentiviral particle packaged cDNA for IGFALS gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IGFALS gene
- Search ViGene Biosciences for IGFALS
CRISPR Products
-
OriGene CRISPR knockouts for IGFALS
-
Santa Cruz Biotechnology (SCBT) CRISPR for IGFALS
- GenScript: Design CRISPR guide RNA sequences for IGFALS
miRNA Products
- Search ViGene Biosciences for IGFALS
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for IGFALS
- Browse OriGene Inhibitory RNA Products For IGFALS
-
ViGene Biosciences ready-to-package AAV shRNAs for IGFALS gene
Clone Products
- Sino Biological Human cDNA Clone for IGFALS
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for IGFALS
- VectorBuilder custom plasmid, inducible vectors for IGFALS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGFALS
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for IGFALS
-
ViGene Biosciences adenoviral particle packaged cDNA for IGFALS gene
-
ViGene Biosciences lentiviral particle packaged cDNA for IGFALS gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IGFALS gene
No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targets and HOMER Transcription for IGFALS Gene
Localization for IGFALS Gene
Subcellular locations from UniProtKB/Swiss-Prot for IGFALS Gene
- Secreted, extracellular space.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| plasma membrane | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | TAS | 1384485 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0042567 | insulin-like growth factor ternary complex | IDA | 9497324 |
| GO:0070062 | extracellular exosome | IDA | 19056867 |
Pathways & Interactions for IGFALS Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Metabolism of proteins | ||
| 2 | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | ||
Pathways by source for IGFALS Gene
2 Reactome pathways for IGFALS Gene
Interacting Proteins for IGFALS Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007155 | cell adhesion | IEA | -- |
| GO:0007165 | signal transduction | TAS | 1384485 |
| GO:0044267 | cellular protein metabolic process | TAS | -- |
No data available for SIGNOR curated interactions for IGFALS Gene
Transcripts for IGFALS Gene
mRNA/cDNA for IGFALS Gene
- (2) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (3) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for IGFALS Gene
- Insulin-like growth factor binding protein, acid labile subunit:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for IGFALS
-
Santa Cruz Biotechnology (SCBT) CRISPR for IGFALS
- GenScript: Design CRISPR guide RNA sequences for IGFALS
miRNA Products
- Search ViGene Biosciences for IGFALS
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for IGFALS
- Browse OriGene Inhibitory RNA Products For IGFALS
-
ViGene Biosciences ready-to-package AAV shRNAs for IGFALS gene
Clone Products
- Sino Biological Human cDNA Clone for IGFALS
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for IGFALS
- VectorBuilder custom plasmid, inducible vectors for IGFALS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGFALS
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for IGFALS Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Adipose (Muscoskeletal System)
- Visceral White Adipocytes Visceral White Adipose
- Body Subcutaneous White Adipose
- Visceral White Adipose
- Inner Cell Mass (Early Embryonic Tissues)
mRNA differential expression in normal tissues according to GTEx for IGFALS Gene
This gene is overexpressed in Liver (x38.2).
This gene is overexpressed in Serum (33.9), Plasma (11.2), and Synovial fluid (10.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for IGFALS Gene
NURSA nuclear receptor signaling pathways regulating expression of IGFALS Gene:
IGFALSSOURCE GeneReport for Unigene cluster for IGFALS Gene:
Hs.839mRNA Expression by UniProt/SwissProt for IGFALS Gene:
P35858-ALS_HUMAN
Tissue specificity:
Plasma.
Evidence on tissue expression from TISSUES for IGFALS Gene
- Liver(4.5)
- Bone marrow(4)
Phenotype-based relationships between genes and organs from Gene ORGANizer for IGFALS Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- endocrine
- nervous
- reproductive
- urinary
Organs:
Head and neck:
- brain
- eye
- head
Abdomen:
- kidney
- pancreas
Pelvis:
- fallopian tube
- ovary
- penis
- prostate
- testicle
- uterus
- vagina
- vas deferens
- vulva
General:
- blood vessel
- peripheral nerve
- peripheral nervous system
Primer Products
-
OriGene qPCR primer pairs and template standards for IGFALS
-
OriGene qPCR primer pairs for IGFALS
Orthologs for IGFALS Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | IGFALS 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | IGFALS 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | IGFALS 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Igfals 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Igfals 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | IGFALS 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | IGFALS 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | IGFALS 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | IGFALS 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | igfals 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | si:ch211-66h3.1 34 |
|
||
| IGFALS 35 |
|
OneToOne | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP007059 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | Toll-7 36 |
|
|
|
| 18w 36 |
|
|
|||
| BG:DS03192.2 36 |
|
|
|||
| CG7896 36 |
|
|
|||
| CG8561 36 |
|
|
|||
| CG5195 36 |
|
|
|||
| trn 36 |
|
|
|||
| CG6749 36 |
|
|
|||
| Tollo 36 |
|
|
|||
| CG9562 36 |
|
|
|||
| haf 35 |
|
OneToMany |
- Species where no ortholog for IGFALS was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for IGFALS Gene
Paralogs for IGFALS Gene
(1) SIMAP similar genes for IGFALS Gene using alignment to 3 proteins:
Pseudogenes.org Pseudogenes for IGFALS Gene
Variants for IGFALS Gene
| SNP ID | Clin | Chr 16 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs121909247 | Pathogenic, Acid-labile subunit deficiency (ACLSD) [MIM:615961] | 1,790,800(-) | GGGAC(C/T)GTGGC | nc-transcript-variant, reference, missense | |
| rs551618643 | Likely pathogenic, Acid-labile subunit deficiency (ACLSD) [MIM:615961] | 1,791,591(+) | CGCGG(C/T)TGTGG | nc-transcript-variant, reference, missense | |
| rs766004600 | Acid-labile subunit deficiency (ACLSD) [MIM:615961] | 1,792,200(+) | CGCCC(A/G)GGACT | nc-transcript-variant, reference, missense | |
| rs774634302 | Acid-labile subunit deficiency (ACLSD) [MIM:615961] | 1,791,688(+) | CTGGA(A/G)CCGGG | nc-transcript-variant, reference, missense | |
| rs776840046 | Acid-labile subunit deficiency (ACLSD) [MIM:615961] | 1,791,100(+) | CAGGT(C/T)GAGCT | nc-transcript-variant, reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv4856n54 | CNV | loss | 21841781 |
| esv2422427 | CNV | duplication | 17116639 |
| nsv1042986 | CNV | loss | 25217958 |
| nsv1051692 | CNV | loss | 25217958 |
| nsv1160328 | CNV | deletion | 26073780 |
| nsv457336 | CNV | loss | 19166990 |
| nsv471069 | CNV | loss | 18288195 |
| nsv482185 | CNV | gain | 20164927 |
| nsv517196 | CNV | gain+loss | 19592680 |
| nsv518641 | CNV | loss | 19592680 |
| nsv571170 | CNV | loss | 21841781 |
| nsv571171 | CNV | gain+loss | 21841781 |
| nsv571172 | CNV | loss | 21841781 |
| nsv827500 | CNV | gain | 20364138 |
| nsv952900 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
96.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.56;
64.99% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for IGFALS Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IGFALS Gene
Disorders for IGFALS Gene
(3) MalaCards diseases for IGFALS Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| acid-labile subunit, deficiency of |
|
|
| 3-m syndrome 1 |
|
|
| noonan syndrome 1 |
|
|
Search IGFALS in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
ALS_HUMAN- Acid-labile subunit deficiency (ACLSD) [MIM:615961]: A disorder characterized by severely reduced serum IGF-I and IGFBP-3 concentrations and mild growth retardation. Pubertal delay in boys and insulin insensitivity are common findings. {ECO:0000269 PubMed:14762184, ECO:0000269 PubMed:16507628, ECO:0000269 PubMed:17726072, ECO:0000269 PubMed:18303074, ECO:0000269 PubMed:19129715, ECO:0000269 PubMed:20389102, ECO:0000269 PubMed:21396577, ECO:0000269 PubMed:23488611}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for IGFALS
No data available for Genatlas for IGFALS Gene
Publications for IGFALS Gene
- Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma metabolic levels and mammographic density. (PMID: 20302654) Biong M. … Kristensen V.N. (BMC Med Genomics 2010) 3 22 46 64
- Three novel IGFALS gene mutations resulting in total ALS and severe circulating IGF-I/IGFBP-3 deficiency in children of different ethnic origins. (PMID: 19129715) Fofanova-Gambetti O.V. … Rosenfeld R.G. (Horm. Res. 2009) 3 4 22 64
- Primary acid-labile subunit deficiency due to recessive IGFALS mutations results in postnatal growth deficit associated with low circulating insulin growth factor (IGF)-I, IGF binding protein-3 levels, and hyperinsulinemia. (PMID: 18303074) Heath K.E. … Campos-Barros A. (J. Clin. Endocrinol. Metab. 2008) 3 4 22 64
- Risk of testicular germ cell tumors and polymorphisms in the insulin-like growth factor genes. (PMID: 18349294) Chia V.M. … McGlynn K.A. (Cancer Epidemiol. Biomarkers Prev. 2008) 3 22 46 64
- Phenotypic effects of null and haploinsufficiency of acid-labile subunit in a family with two novel IGFALS gene mutations. (PMID: 17726072) DomenAc H.M. … Jasper H.G. (J. Clin. Endocrinol. Metab. 2007) 3 4 22 64
Products for IGFALS Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for IGFALS
- Search Origene for MassSpec and Protein Over-expression Lysates for IGFALS
- Origene Custom Protein Services for IGFALS
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for IGFALS
- Browse OriGene Inhibitory RNA Products For IGFALS
- OriGene qPCR primer pairs and template standards for IGFALS
- OriGene qPCR primer pairs for IGFALS
- OriGene CRISPR knockouts for IGFALS
- OriGene ORF clones in human for IGFALS
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For IGFALS
- GenScript: Next-day shipping cDNA ORF clone for IGFALS in any vector
- GenScript Custom Purified and Recombinant Proteins Services for IGFALS
- GenScript Custom Assay Services for IGFALS
- GenScript Custom overexpressing Cell Line Services for IGFALS
- GenScript: Design CRISPR guide RNA sequences for IGFALS
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for IGFALS
- Sino Biological Human cDNA Clone for IGFALS
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- Sino Biological Cell Lysates
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for IGFALS
- Novus Biologicals proteins and lysates for IGFALS
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for IGFALS
- Abcam proteins for IGFALS
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Invitrogen Antibodies for IGFALS
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for IGFALS
- antibodies-online Antibodies for IGFALS: See all 47
- antibodies-online Kits for IGFALS: See all 11
- antibodies-online Proteins for IGFALS: See all 4
- Search antibodies-online for peptides
- GeneTex IGFALS antibody for IGFALS
- Search GeneTex for Proteins for IGFALS
- ViGene Biosciences adenoviral particle packaged cDNA for IGFALS gene
- ViGene Biosciences lentiviral particle packaged cDNA for IGFALS gene
- ViGene Biosciences ready-to-package AAV shRNAs for IGFALS gene
- Search ViGene Biosciences for IGFALS
- Santa Cruz Biotechnology (SCBT) Antibodies for IGFALS
- Search Santa Cruz Biotechnology (SCBT) for IGFALS siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for IGFALS
- Horizon Cell Lines for IGFALS
- Cyagen custom Knockout/knockin (KOKI) mouse models for IGFALS
- VectorBuilder custom plasmid, inducible vectors for IGFALS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGFALS
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for IGFALS Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
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