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Aliases for IGF2-AS Gene

Subcategory (RNA class) for IGF2-AS Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for IGF2-AS Gene

  • IGF2 Antisense RNA 2 3 5
  • Insulin-Like Growth Factor 2 Antisense 1 (Non-Protein Coding) 2 3
  • IGF2 Antisense RNA 1 (Non-Protein Coding) 2 3
  • IGF2-AS1 3 4
  • IGF2AS 3 4
  • Putative Insulin-Like Growth Factor 2 Antisense Gene Protein 1 4
  • Insulin-Like Growth Factor II, Antisense 3
  • Insulin-Like Growth Factor 2, Antisense 2
  • IGF2 Antisense RNA (Non-Protein Coding) 2
  • IGF2 Antisense Gene Protein 1 4
  • PEG8/IGF2AS, Imprinting 3
  • IGF2 Antisense RNA 1 4
  • PEG8/IGF2AS Protein 4
  • PEG8 3

External Ids for IGF2-AS Gene

Previous HGNC Symbols for IGF2-AS Gene

  • IGF2AS

Previous GeneCards Identifiers for IGF2-AS Gene

  • GC11P002163
  • GC11P002167
  • GC11P002171

Summaries for IGF2-AS Gene

Entrez Gene Summary for IGF2-AS Gene

  • This gene is expressed in antisense to the insulin-like growth factor 2 (IGF2) gene and is imprinted and paternally expressed. It is thought to be non-coding because the putative protein is not conserved and translation is predicted to trigger nonsense mediated decay (NMD). Transcripts from this gene are produced in tumors and may function to suppress cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]

GeneCards Summary for IGF2-AS Gene

IGF2-AS (IGF2 Antisense RNA) is an RNA Gene, and is affiliated with the non-coding RNA class. Among its related pathways are GPCR Pathway and Nanog in Mammalian ESC Pluripotency.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGF2-AS Gene

Genomics for IGF2-AS Gene

Regulatory Elements for IGF2-AS Gene

Enhancers for IGF2-AS Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F002102 0.4 Ensembl 12.5 -37.5 -37501 0.4 ELF3 MLX ARID4B ZNF48 ZSCAN9 RAD21 RARA MIXL1 THAP11 MXD4 MIR483 IGF2-AS IGF2 ENSG00000240801 KRTAP5-6 FAM99B LOC100505570 GC11P002077
GH11F002108 0.9 Ensembl ENCODE 12.5 -31.0 -31047 1.5 CTCF ELF3 TFAP4 SAP130 ZFP64 MAX RAD21 ZNF48 TEAD3 GLIS2 MIR483 IGF2-AS IGF2 TNNT3 TH ENSG00000240801 GC11P002077
GH11F002099 1.2 Ensembl ENCODE 11.9 -40.5 -40501 2.0 CTCF KLF1 ATF1 SAP130 ARID4B ZIC2 GLIS2 CREM THAP11 GATAD2A ENSG00000240801 MIR483 IGF2-AS IGF2 GC11P002077
GH11F002074 0.7 ENCODE 11.7 -66.1 -66056 0.2 CTCF HLF RAD21 MIR483 IGF2-AS IGF2 ENSG00000199550 CD81 GC11P002077 GC11M002043
GH11F002095 1.1 Ensembl ENCODE 11.5 -43.7 -43683 3.6 ELF3 TBP CBX3 MLX ARID4B DMAP1 THRB ZNF48 ZSCAN9 RARA MIR483 IGF2-AS IGF2 GC11P002077 ENSG00000240801
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around IGF2-AS on UCSC Golden Path with GeneCards custom track

Genomic Location for IGF2-AS Gene

2,140,501 bp from pter
2,148,666 bp from pter
8,166 bases
Plus strand

Genomic View for IGF2-AS Gene

Genes around IGF2-AS on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
IGF2-AS Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for IGF2-AS Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for IGF2-AS Gene

Proteins for IGF2-AS Gene

  • Protein details for IGF2-AS Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative insulin-like growth factor 2 antisense gene protein
    Protein Accession:
    Secondary Accessions:
    • A5PKV8
    • A6NNQ2
    • Q7Z712
    • Q9P2W0

    Protein attributes for IGF2-AS Gene

    168 amino acids
    Molecular mass:
    18035 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA90470.1; Type=Frameshift; Positions=162; Evidence={ECO:0000305};

neXtProt entry for IGF2-AS Gene

Post-translational modifications for IGF2-AS Gene

No Post-translational modifications

No data available for DME Specific Peptides for IGF2-AS Gene

Domains & Families for IGF2-AS Gene

Gene Families for IGF2-AS Gene

Protein Domains for IGF2-AS Gene


Suggested Antigen Peptide Sequences for IGF2-AS Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with IGF2-AS: view

No data available for UniProtKB/Swiss-Prot for IGF2-AS Gene

Function for IGF2-AS Gene

Phenotypes for IGF2-AS Gene

genes like me logo Genes that share phenotypes with IGF2-AS: view

Animal Model Products

miRNA for IGF2-AS Gene

miRTarBase miRNAs that target IGF2-AS

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for IGF2-AS Gene

Localization for IGF2-AS Gene

Subcellular locations from

Jensen Localization Image for IGF2-AS Gene COMPARTMENTS Subcellular localization image for IGF2-AS gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for IGF2-AS Gene

Pathways & Interactions for IGF2-AS Gene

genes like me logo Genes that share pathways with IGF2-AS: view

Interacting Proteins for IGF2-AS Gene

Gene Ontology (GO) - Biological Process for IGF2-AS Gene


No data available for SIGNOR curated interactions for IGF2-AS Gene

Transcripts for IGF2-AS Gene

mRNA/cDNA for IGF2-AS Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(22) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for IGF2-AS Gene

IGF2 antisense RNA:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for IGF2-AS Gene

No ASD Table

Relevant External Links for IGF2-AS Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for IGF2-AS Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for IGF2-AS Gene

mRNA differential expression in normal tissues according to GTEx for IGF2-AS Gene

This gene is overexpressed in Liver (x16.6).

Protein differential expression in normal tissues from HIPED for IGF2-AS Gene

This gene is overexpressed in Plasma (51.5) and Liver, secretome (17.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for IGF2-AS Gene

Protein tissue co-expression partners for IGF2-AS Gene

SOURCE GeneReport for Unigene cluster for IGF2-AS Gene:

genes like me logo Genes that share expression patterns with IGF2-AS: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for IGF2-AS Gene

Orthologs for IGF2-AS Gene

Evolution for IGF2-AS Gene

Gene Tree for IGF2-AS (if available)
Gene Tree for IGF2-AS (if available)

No data available for Orthologs for IGF2-AS Gene

Paralogs for IGF2-AS Gene

No data available for Paralogs for IGF2-AS Gene

Variants for IGF2-AS Gene

Sequence variations from dbSNP and Humsavar for IGF2-AS Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs758689893 Uncertain significance 2,140,215(+) TACCC(C/T)GTCCT intron-variant, upstream-variant-2KB, reference, missense
rs1003482 -- 2,145,173(+) GCCTT(C/T)TGCAG intron-variant
rs1003483 -- 2,146,313(+) CTCCT(G/T)TCTCC intron-variant, nc-transcript-variant, downstream-variant-500B
rs1003484 -- 2,146,388(+) CGCTC(A/G)CTCCC intron-variant, nc-transcript-variant, downstream-variant-500B
rs1004446 -- 2,148,913(-) GTTCT(C/T)CTTTA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for IGF2-AS Gene

Variant ID Type Subtype PubMed ID
esv2673506 CNV deletion 23128226
nsv467645 CNV gain 19166990
nsv553047 CNV gain 21841781
nsv553068 CNV loss 21841781
nsv553069 CNV loss 21841781
nsv825707 CNV gain 20364138
nsv951284 CNV deletion 24416366

Relevant External Links for IGF2-AS Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for IGF2-AS Gene

Disorders for IGF2-AS Gene

Relevant External Links for IGF2-AS

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for IGF2-AS Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for IGF2-AS Gene

Publications for IGF2-AS Gene

  1. Expression and imprinting status of human PEG8/IGF2AS, a paternally expressed antisense transcript from the IGF2 locus, in Wilms' tumors. (PMID: 10731720) Okutsu T. … Ishino F. (J. Biochem. 2000) 2 3 4 22 64
  2. Loss of imprinting of IGF2 sense and antisense transcripts in Wilms' tumor. (PMID: 12702581) Vu T.H. … Hoffman A.R. (Cancer Res. 2003) 3 4 22 64
  3. Insulin-like growth factor pathway genetic polymorphisms, circulating IGF1 and IGFBP3, and prostate cancer survival. (PMID: 24824313) Cao Y. … Ma J. (J. Natl. Cancer Inst. 2014) 3 64
  4. Methylation alterations at imprinted genes detected among long-term shiftworkers. (PMID: 23193016) Jacobs D.I. … Zhu Y. (Environ. Mol. Mutagen. 2013) 3 64
  5. Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. (PMID: 21829393) Plagnol V. … Todd J.A. (PLoS Genet. 2011) 3 64

Products for IGF2-AS Gene

Sources for IGF2-AS Gene

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