Aliases for IGF1 Gene
Aliases for IGF1 Gene
External Ids for IGF1 Gene
- HGNC: 5464
- Entrez Gene: 3479
- Ensembl: ENSG00000017427
- OMIM: 147440
- UniProtKB: P05019
Previous GeneCards Identifiers for IGF1 Gene
- GC12M101888
- GC12M102748
- GC12M101292
- GC12M099849
Summaries for IGF1 Gene
-
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
GeneCards Summary for IGF1 Gene
IGF1 (Insulin Like Growth Factor 1) is a Protein Coding gene. Diseases associated with IGF1 include Insulin-Like Growth Factor I and Pituitary Gland Disease. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Peptide hormone metabolism. Gene Ontology (GO) annotations related to this gene include growth factor activity and integrin binding. An important paralog of this gene is IGF2.
UniProtKB/Swiss-Prot for IGF1 Gene
-
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation (PubMed:21076856, PubMed:24132240). Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb (By similarity). Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1 (PubMed:19578119, PubMed:22351760, PubMed:23696648, PubMed:23243309).
-
Insulin receptors (IRs) and insulin-like growth factor receptors (IGFRs) are formed from two subunits, each of which is comprised of an extracellular alpha-subunit and a transmembrane beta-subunit with intracellular tyrosine kinase activity. IR homodimers are activated by insulin.
Additional gene information for IGF1 Gene
- Monarch Initiative
- Search for IGF1 at DataMed
- Search for IGF1 at HumanCyc
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IGF1 Gene
Genomics for IGF1 Gene
GeneHancer (GH) Regulatory Elements for IGF1 Gene
Promoters and enhancers for IGF1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around IGF1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the IGF1 gene promoter:
Regulatory Element Products
Genomic Locations for IGF1 Gene
Genomic Locations for IGF1 Gene
- chr12:102,395,867-102,481,786
- (GRCh38/hg38)
- Size:
- 85,920 bases
- Orientation:
- Minus strand
- chr12:102,789,645-102,874,423
- (GRCh37/hg19)
Genomic View for IGF1 Gene
Genes around IGF1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q23.2 by Ensembl
- 12q23.2 by Entrez Gene
- 12q23.2 by HGNC
IGF1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IGF1 Gene
Proteins for IGF1 Gene
-
Protein details for IGF1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P05019-IGF1_HUMAN
- Recommended name:
- Insulin-like growth factor I
- Protein Accession:
- P05019
- B2RWM7
- E9PD02
- P01343
- Q14620
Protein attributes for IGF1 Gene
- Size:
- 195 amino acids
- Molecular mass:
- 21841 Da
- Quaternary structure:
-
- Forms a ternary complex with IGFR1 and ITGAV:ITGB3 (PubMed:19578119). Forms a ternary complex with IGFR1 and ITGA6:ITGB4 (PubMed:22351760, PubMed:23696648).
- SequenceCaution:
-
- Sequence=CAA27250.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for IGF1 Gene
Protein Expression for IGF1 Gene
Post-translational modifications for IGF1 Gene
No Post-translational modifications
Other Protein References for IGF1 Gene
Antibody Products
- R&D Systems Antibodies for IGF1 (IGF-I)
-
Custom Antibody ServicesOriGene Antibodies for IGF1
- CF805792
- TA805792
- CF805748
- TA805748
- TA805728
- TA350696
- TA348004
- TA332383
- TA328347
- TA319033
- TA311185
- PP1020P2
- PP1020P1
- PP1020B2
- PP1020B1
- BP561
- BM509
- BM2079
- AP33340PU-T
- AP33340PU-S
- AP33340PU-N
- AM50335PU-S
- AM50335PU-N
- AM50117PU-T
- AM50117PU-S
- AM50117PU-N
- AM33375SU-S
- AM33375SU-N
- AM33345PU-T
- AM33345PU-S
- AM33345PU-N
- Novus Biologicals Antibodies for IGF1
-
Abcam antibodies for IGF1
-
Cloud-Clone Corp. Antibodies for IGF1
- Invitrogen Antibodies for IGF1
- antibodies-online: Search results for 448 available IGF1 Antibodies ranked by validation data
- Compare Top IGF1 Antibodies
-
Recommended
- 1 RIA Antibody (anti-rat)
- 1 IHC (p) Antibody (anti-rat)
- 1 IHC Antibody (anti-rat)
- 2 InhA Antibodies (anti-rat)
- 2 IP Antibodies (anti-rat)
- 4 Neut Antibodies (anti-rat)
- 5 IF Antibodies (anti-rat)
- 22 FACS Antibodies (anti-rat)
- 24 IF (p) Antibodies (anti-rat)
- 76 WB Antibodies (anti-rat)
- 1 RIA Antibody (anti-mouse)
- 1 IHC Antibody (anti-mouse)
- 2 InhA Antibodies (anti-mouse)
- 2 IHC (p) Antibodies (anti-mouse)
- 4 Neut Antibodies (anti-mouse)
- 5 IF Antibodies (anti-mouse)
- 22 FACS Antibodies (anti-mouse)
- 24 IF (p) Antibodies (anti-mouse)
- 136 WB Antibodies (anti-mouse)
- 1 EIA Antibody (anti-human)
- 2 InhA Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 2 IHC (fro) Antibodies (anti-human)
- 4 Neut Antibodies (anti-human)
- 4 IHC (p) Antibodies (anti-human)
- 7 IF Antibodies (anti-human)
- 8 RIA Antibodies (anti-human)
- 17 IHC Antibodies (anti-human)
- 23 FACS Antibodies (anti-human)
- 24 IF (p) Antibodies (anti-human)
- 222 WB Antibodies (anti-human)
- GeneTex IGF1 antibody for IGF1
-
Santa Cruz Biotechnology (SCBT) Antibodies for IGF1
- Sino Biological Antibodies for IGF1
Protein Products
- R&D Systems Proteins and Enzymes for IGF1 (IGF-I)
- Search Origene for MassSpec and Protein Over-expression Lysates for IGF1
- Origene Custom Protein Services for IGF1
- Sino Biological Recombinant Proteins for IGF1
- Browse Sino Biological Cell Lysates
- ProSpec Recombinant Proteins for IGF1
-
Cloud-Clone Corp. Proteins for IGF1
- GeneTex Proteins for IGF1
Assay Products
- R&D Systems ELISAs and other biochemical assays for IGF1 (IGF-I)
- antibodies-online: Search results for 183 available IGF1 Elisa Kits ranked by validation data
- Compare Top IGF1 Elisa Kits
-
Recommended
- 2 Wild boar (Sus scrofa) ELISA Kits
- 1 Turkey ELISA Kit
- 5 Sheep (Ovine) ELISA Kits
- 28 Rat (Rattus) ELISA Kits
- 11 Rabbit ELISA Kits
- 13 Pig (Porcine) ELISA Kits
- 38 Mouse (Murine) ELISA Kits
- 7 Monkey ELISA Kits
- 31 Human ELISA Kits
- 3 Horse (Equine) ELISA Kits
- 1 Hamster ELISA Kit
- 5 Guinea Pig ELISA Kits
- 5 Goat ELISA Kits
- 1 Fish ELISA Kit
- 1 Duck ELISA Kit
- 10 Dog (Canine) ELISA Kits
- 1 Deer ELISA Kit
- 16 Cow (Bovine) ELISA Kits
- 12 Chicken ELISA Kits
- 1 All Species ELISA Kit
-
Abcam assays for IGF1
No data available for DME Specific Peptides for IGF1 Gene
Domains & Families for IGF1 Gene
Gene Families for IGF1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted secreted proteins
Protein Domains for IGF1 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for IGF1 Gene
Graphical View of Domain Structure for InterPro Entry
P05019- Family:
-
- Belongs to the insulin family.
Function for IGF1 Gene
Molecular function for IGF1 Gene
- GENATLAS Biochemistry:
- insulin-like growth factor 1,expressed in liver,regulator of somatic growth and cellular proliferation,inducer of the phosphatidylinositol 3-kinase survival pathway through activation of AKT1,AKT2,inhibited by TNF in its neuroprotective role,also inducer of calcineurin mediated signaling and activation of GATA2,associated with intrauterine growth retardation and severe short stature in a patient carrying a homozygous deletion of IGF1
- UniProtKB/Swiss-Prot Function:
- The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation (PubMed:21076856, PubMed:24132240). Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb (By similarity). Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1 (PubMed:19578119, PubMed:22351760, PubMed:23696648, PubMed:23243309).
LifeMap Function Summary for IGF1 Gene
During embryonic development, IGF1 as signaling molecule is secreted from the following cells
- Bone
- Hair
- Liver
- Head Mesenchyme
- Cartilage
It affects the following cells:
-
Bone
- Chondrocytes (Vertebrae)
- Chondrocytes (Rib)
- Endochondral Osteoblasts (Vertebrae)
- Endochondral Osteoblasts (Rib)
- Endochondral Preosteoblasts (Caudal Facial Endochondral Bones)
- Endochondral Preosteoblasts (Rostral Endochondral Facial Bones)
- Endochondral Preosteoblasts (Endochondral Facial Bones)
- Immature Endochondral Osteoblasts (Autopod Periosteum)
- Immature Endochondral Osteoblasts (Zeugopod Periosteum)
- Immature Endochondral Osteoblasts (Stylopod Periosteum)
- Immature Endochondral Osteoblasts (Vertebrae)
- Immature Endochondral Osteoblasts (Rib)
- Prehypertrophic Chondrocytes (Vertebrae)
- Prehypertrophic Chondrocytes (Rib)
- Placenta
- Hair
- Ovary
- Liver
IGF1 as growth factor is involved in stem cell differentiation protocols towards the derivation of the following cells:
- Neural Crest
- Heart
- Neurons
-
Spinal Cord
- Astrocytes-like cells
- B27-induced oligodendrocyte-like cells
- Expanded oligodendrocyte progenitor cells
- Lateral motor column neuron-like cells
- Matured motor neuron-like cells
- Motor neuron-like cells
- Motor neuron-like cells
- Oligodendrocyte precursor cells
- Oligodendrocyte precursor cells
- Oligodendrocyte progenitor cells
- Oligodendrocyte-like cells
- Oligodendrocyte-like cells
- Oligodendrocyte-like cells
- Precursor lateral motor column neuron EBs
- Spinal GABA neurons
- Endothelium
- Pancreas
- Brain
- Glial Cells
- Cartilage
- Skeletal Muscle
- Neural Ectoderm
- Adipose
- Thyroid
Phenotypes From GWAS Catalog for IGF1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005158 | insulin receptor binding | IPI | 8452530 |
| GO:0005159 | insulin-like growth factor receptor binding | IPI | 8452530 |
| GO:0005178 | integrin binding | IDA | 19578119 |
| GO:0005179 | hormone activity | IDA | 7188854 |
| GO:0005515 | protein binding | IPI | 8452530 |
Phenotypes for IGF1 Gene
- MGI mutant phenotypes for IGF1:
-
inferred from 9 alleles
- nervous system phenotype
- normal phenotype
- homeostasis/metabolism phenotype
- respiratory system phenotype
- muscle phenotype
- cardiovascular system phenotype
- mortality/aging
- immune system phenotype
- cellular phenotype
- growth/size/body region phenotype
- neoplasm
- endocrine/exocrine gland phenotype
- reproductive system phenotype
- hearing/vestibular/ear phenotype
- integument phenotype
- hematopoietic system phenotype
- skeleton phenotype
- renal/urinary system phenotype
- adipose tissue phenotype
- limbs/digits/tail phenotype
- GenomeRNAi human phenotypes for IGF1:
Animal Models for IGF1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for IGF1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for IGF1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IGF1 gene
- Search ViGene Biosciences for IGF1
CRISPR Products
-
OriGene CRISPR knockouts for IGF1
- genomics-online: gRNA clones - Search results for 235 available IGF1 gene related products
- Overview of 235 available IGF1 gene related products
- Applied Biological Materials CRISPR for IGF1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for IGF1
- GenScript: Design CRISPR guide RNA sequences for IGF1
miRNA for IGF1 Gene
- miRTarBase miRNAs that target IGF1
-
- hsa-mir-1-3p (MIRT001844)
- hsa-mir-27a-3p (MIRT006431)
- hsa-mir-483-3p (MIRT053205)
- hsa-let-7e-5p (MIRT054579)
- hsa-mir-190b (MIRT054581)
- hsa-mir-299-3p (MIRT054905)
- hsa-let-7i-5p (MIRT437345)
- hsa-mir-199a-3p (MIRT438017)
- hsa-mir-190a-5p (MIRT438368)
- hsa-mir-29a-3p (MIRT438679)
- hsa-mir-6739-3p (MIRT449939)
- hsa-mir-576-5p (MIRT449940)
- hsa-mir-7156-5p (MIRT449941)
- hsa-mir-4273 (MIRT449942)
- hsa-mir-7641 (MIRT449943)
- hsa-mir-539-5p (MIRT449944)
- hsa-mir-6516-5p (MIRT523024)
- hsa-mir-455-3p (MIRT523025)
- hsa-mir-7847-3p (MIRT523026)
- hsa-mir-6880-5p (MIRT523027)
- hsa-mir-6851-5p (MIRT523028)
- hsa-mir-3689d (MIRT523029)
- hsa-mir-6499-3p (MIRT523030)
- hsa-mir-6086 (MIRT523031)
- hsa-mir-377-5p (MIRT523032)
- hsa-mir-6134 (MIRT523033)
- hsa-mir-302a-5p (MIRT523034)
- hsa-mir-6840-3p (MIRT523035)
- hsa-mir-665 (MIRT523036)
- hsa-mir-4459 (MIRT523037)
- hsa-mir-6771-3p (MIRT523038)
- hsa-mir-1277-5p (MIRT523039)
- hsa-mir-190a-3p (MIRT523040)
- hsa-mir-211-3p (MIRT523041)
- hsa-mir-5011-5p (MIRT523042)
- hsa-mir-4662a-3p (MIRT523043)
- hsa-mir-1305 (MIRT536724)
- hsa-mir-4753-3p (MIRT536725)
- hsa-mir-421 (MIRT536726)
- hsa-mir-505-3p (MIRT536727)
- hsa-mir-7159-5p (MIRT536728)
- hsa-mir-130b-5p (MIRT536729)
- hsa-mir-3065-5p (MIRT536730)
- hsa-mir-10a-3p (MIRT536731)
- hsa-mir-6513-5p (MIRT632817)
- hsa-mir-887-5p (MIRT632818)
- hsa-mir-3913-5p (MIRT632819)
- hsa-mir-3122 (MIRT632820)
- hsa-mir-450a-1-3p (MIRT632821)
- hsa-mir-6780a-5p (MIRT632822)
- hsa-mir-6779-5p (MIRT632823)
- hsa-mir-3689c (MIRT632824)
- hsa-mir-3689b-3p (MIRT632825)
- hsa-mir-3689a-3p (MIRT632826)
- hsa-mir-30b-3p (MIRT632827)
- hsa-mir-1273h-5p (MIRT632828)
- hsa-mir-6788-5p (MIRT632829)
- hsa-mir-30c-2-3p (MIRT632830)
- hsa-mir-30c-1-3p (MIRT632831)
- hsa-mir-6514-3p (MIRT632832)
- hsa-mir-6765-5p (MIRT632833)
- hsa-mir-7977 (MIRT632834)
- hsa-mir-6799-5p (MIRT632835)
- hsa-mir-6883-5p (MIRT632836)
- hsa-mir-6785-5p (MIRT632837)
- hsa-mir-4728-5p (MIRT632838)
- hsa-mir-149-3p (MIRT632839)
- hsa-mir-7106-5p (MIRT632840)
- hsa-mir-24-3p (MIRT632841)
- hsa-mir-4284 (MIRT632842)
- hsa-mir-7160-5p (MIRT632843)
- hsa-mir-6847-3p (MIRT632844)
- hsa-mir-6811-3p (MIRT632845)
- hsa-mir-214-5p (MIRT632846)
- hsa-mir-6884-5p (MIRT632847)
- hsa-mir-485-5p (MIRT632848)
- hsa-mir-6087 (MIRT632849)
- hsa-mir-3197 (MIRT632850)
- hsa-mir-4649-3p (MIRT632851)
- hsa-mir-4478 (MIRT632852)
- hsa-mir-4419b (MIRT632853)
- hsa-mir-3929 (MIRT632854)
- hsa-mir-574-5p (MIRT657215)
- hsa-mir-297 (MIRT657216)
- hsa-mir-6867-5p (MIRT657217)
- hsa-mir-4711-3p (MIRT657218)
- hsa-mir-223-5p (MIRT657219)
- hsa-mir-567 (MIRT657220)
- hsa-mir-133a-3p (MIRT731340)
- hsa-mir-18b-5p (MIRT731359)
- hsa-mir-28-5p (MIRT731420)
- hsa-mir-603 (MIRT731735)
- hsa-mir-130b-3p (MIRT732179)
- hsa-mir-98-5p (MIRT732227)
- hsa-mir-26b-5p (MIRT732599)
- hsa-mir-129-5p (MIRT733164)
- hsa-mir-128-3p (MIRT733519)
- hsa-mir-26a-5p (MIRT734538)
miRNA Products
- Search ViGene Biosciences for IGF1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for IGF1
- Browse OriGene Inhibitory RNA Products For IGF1
- genomics-online: shRNA clones - Search results for 235 available IGF1 gene related products
- Overview of 235 available IGF1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for IGF1 gene
Clone Products
- Sino Biological Human cDNA Clone for IGF1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IGF1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGF1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for IGF1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for IGF1
-
ViGene Biosciences adenoviral particle packaged cDNA for IGF1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for IGF1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IGF1 gene
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for IGF1 Gene
Localization for IGF1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for IGF1 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| nucleus | 3 |
| cytosol | 3 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| peroxisome | 2 |
| endoplasmic reticulum | 2 |
| lysosome | 2 |
| golgi apparatus | 1 |
| endosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | IEA,IDA | 7188854 |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016942 | insulin-like growth factor binding protein complex | IC | 10766744 |
| GO:0031093 | platelet alpha granule lumen | TAS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for IGF1 Gene
Pathways & Interactions for IGF1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Apoptotic Pathways in Synovial Fibroblasts |
.74
.66
|
.65
.61
.60
.57
|
| 2 | GPCR Pathway |
.73
.62
|
.55
|
| 3 | Endometrial cancer |
.52
.47
|
.32
|
| 4 | ERK Signaling |
.61
.58
|
.49
|
| 5 | Nanog in Mammalian ESC Pluripotency |
.61
|
.48
|
Pathways by source for IGF1 Gene
12 BioSystems pathways for IGF1 Gene
13 Reactome pathways for IGF1 Gene
10 GeneGo (Thomson Reuters) pathways for IGF1 Gene
2 R&D Systems pathways for IGF1 Gene
Interacting Proteins for IGF1 Gene
Selected Interacting proteins:
P05019-IGF1_HUMAN
ENSP00000302665
for IGF1 Gene via
IID
STRING
UniProtKB
SIGNOR curated interactions for IGF1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000187 | activation of MAPK activity | IMP | 22351760 |
| GO:0001501 | skeletal system development | TAS | 10448861 |
| GO:0001775 | cell activation | IDA | 22797923 |
| GO:0002576 | platelet degranulation | TAS | -- |
| GO:0006260 | DNA replication | TAS | 10766744 |
Drugs & Compounds for IGF1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| N,N-bis(3-(D-gluconamido)propyl)deoxycholamide | Experimental | Pharma | Target | 0 | ||
| N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate | Experimental | Pharma | Target | 0 | ||
| Anesthetics | Pharma | 10650 | ||||
| Anesthetics, Local | Pharma | 3866 | ||||
| insulin | Pharma | 4893 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Insulin (human) recombinant |
|
11061-68-0 |
|
|
||
| Picropodophyllotoxin |
|
477-47-4 |
|
|
(5) Tocris Compounds for IGF1 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Demethylasterriquinone B1 | Selective insulin RTK activator | 78860-34-1 |
| GSK 1838705 | Potent IR and IGF1R inhibitor; also inhibits anaplastic lymphoma kinase (ALK) | 1116235-97-2 |
| Insulin (human) recombinant | Endogenous peptide agonist | 11061-68-0 |
| Picropodophyllotoxin | Selective IGF1R inhibitor | 477-47-4 |
| PQ 401 | IGF1R inhibitor | 196868-63-0 |
(3) ApexBio Compounds for IGF1 Gene
| Compound | Action | Cas Number |
|---|---|---|
| Demethylasterriquinone B1 | 78860-34-1 | |
| HNGF6A | 1093111-54-6 | |
| Insulin (human) recombinant expressed in yeast | peptide hormone | 11061-68-0 |
Transcripts for IGF1 Gene
mRNA/cDNA for IGF1 Gene
- (9) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (161) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for IGF1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for IGF1
- genomics-online: gRNA clones - Search results for 235 available IGF1 gene related products
- Overview of 235 available IGF1 gene related products
- Applied Biological Materials CRISPR for IGF1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for IGF1
- GenScript: Design CRISPR guide RNA sequences for IGF1
miRNA Products
- Search ViGene Biosciences for IGF1
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for IGF1
- Browse OriGene Inhibitory RNA Products For IGF1
- genomics-online: shRNA clones - Search results for 235 available IGF1 gene related products
- Overview of 235 available IGF1 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for IGF1 gene
Clone Products
- Sino Biological Human cDNA Clone for IGF1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IGF1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGF1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for IGF1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for IGF1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Bone (Muscoskeletal System)
- Chondrocytes Vertebrae
- Endochondral Osteoblasts Rostral Endochondral Facial Bones
- Prechondrocytes Stylopod Epiphyseal End
- Prechondrocytes Rostral Synchondroses
- Prechondrocytes Zeugopod Epiphyseal End
-
Cartilage (Muscoskeletal System)
- Chondrocytes Vertebrae
- Prechondrocytes Stylopod Epiphyseal End
- Prechondrocytes Rostral Synchondroses
- Prechondrocytes Zeugopod Epiphyseal End
- Prechondrocytes Synchondroses
-
Brain (Nervous System)
- Adult Dopaminergic Neurons Substantia Nigra pars Compacta
- Cerebellum
- Midbrain tegmentum
-
Neurons
- Adult Dopaminergic Neurons Substantia Nigra pars Compacta
- AII Amacrine Cells Inner Nuclear Layer
- Type1 Off Cone Bipolar Cells Inner Nuclear Layer
-
Kidney (Urinary System)
- Metanephric Mesenchyme Cells Metanephric Mesenchyme
- Metanephric Mesenchyme
- Metanephros
-
Heart (Cardiovascular System)
- Primitive Heart Tube Cells Primitive Heart Tube
- Atrioventricular Canal Cells Atrioventricular Canal
- Heart Tube
-
Eye (Sensory Organs)
- AII Amacrine Cells Inner Nuclear Layer
- Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
- Type1 Off Cone Bipolar Cells Inner Nuclear Layer
-
Dermis (Integumentary System)
- Zigzag Dermal Papilla Cells Dermal Papilla
- Guard Dermal Papilla Cells Dermal Papilla
- Human neonatal dermal fibroblasts (Dermagraft)
-
Adipose (Muscoskeletal System)
- Visceral White Preadipocytes Visceral White Adipose
- Visceral White Adipose
-
Hair (Integumentary System)
- Zigzag Dermal Papilla Cells Dermal Papilla
- Guard Dermal Papilla Cells Dermal Papilla
-
Head Mesenchyme (Muscoskeletal System)
- Prechondrocytes Branchial Arch 2
- Frontonasal Process
-
Limb (Muscoskeletal System)
- Prechondrocytic Mesenchymal Cells Zeugopod
- Mesenchymal Condensate Cells Zeugopod
- Neural Tube (Nervous System)
- Fibroblasts (Uncategorized)
-
Epiblast (Early Embryonic Tissues)
- Epiblast Cells Epiblast
-
Epithelial Cells
- Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
-
Zygote (Early Embryonic Tissues)
- 8-Cell Embryo Morula
-
Inner Cell Mass (Early Embryo)
- 8-Cell Embryo Morula
-
Trophoblast (Extraembryonic Tissues)
- 8-Cell Embryo Morula
-
Liver (Hepatobiliary System)
- Hepatocytes Liver Lobule
-
Tooth (Integumentary System)
- Stellate Reticulum Cells Dental Core
- Intermediate Mesoderm (Gastrulation Derivatives)
- Pancreas (Endocrine System)
- Glial Cells (Uncategorized)
- Peripheral Nervous System (Nervous System)
-
Uterus (Reproductive System)
-
Prostate (Endocrine System)
-
Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for IGF1 Gene
This gene is overexpressed in Adipose - Visceral (Omentum) (x4.2).
This gene is overexpressed in Serum (25.5), Plasma (19.7), Skin (16.2), and Synovial fluid (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for IGF1 Gene
NURSA nuclear receptor signaling pathways regulating expression of IGF1 Gene:
IGF1SOURCE GeneReport for Unigene cluster for IGF1 Gene:
Hs.160562Evidence on tissue expression from TISSUES for IGF1 Gene
- Liver(4.8)
- Nervous system(4.7)
- Muscle(3.7)
- Blood(3.4)
- Heart(3.3)
- Bone(3.2)
- Intestine(3.2)
- Thyroid gland(3.1)
- Kidney(2.9)
- Adrenal gland(2.7)
- Skin(2.6)
- Lung(2.5)
- Bone marrow(2.4)
- Eye(2.3)
- Pancreas(2.3)
- Spleen(2.2)
- Gall bladder(2.1)
- Stomach(2.1)
- Urine(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for IGF1 Gene
Germ Layers:
- ectoderm
- mesoderm
Systems:
- integumentary
- nervous
- skeletal muscle
- skeleton
Organs:
Head and neck:
- brain
- chin
- eye
- eyelid
- face
- head
- jaw
- mandible
- maxilla
- mouth
- neck
- skull
Thorax:
- chest wall
- clavicle
- rib
- rib cage
- scapula
- sternum
Pelvis:
- pelvis
Limb:
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
General:
- skin
- spinal column
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for IGF1
-
OriGene qPCR primer pairs and template standards for IGF1
- genomics-online: primer clones - Search results for 235 available IGF1 gene related products
- Overview of 235 available IGF1 gene related products
No data available for mRNA Expression by UniProt/SwissProt for IGF1 Gene
Orthologs for IGF1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | IGF1 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | IGF1 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | IGF1 33 |
|
||
| IGF-I 34 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Igf1 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Igf1 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | IGF1 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | IGF1 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | IGF1 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | IGF1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100486334 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | igf1-A 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | igf1 33 34 |
|
||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.11904 33 |
|
- Species where no ortholog for IGF1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for IGF1 Gene
(3) SIMAP similar genes for IGF1 Gene using alignment to 6 proteins:
Variants for IGF1 Gene
| SNP ID | Clin | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1042723142 | uncertain-significance, Insulin-like growth factor I deficiency | 102,397,567(-) | G/T | 3_prime_UTR_variant, genic_downstream_transcript_variant | |
| rs1048168367 | uncertain-significance, Insulin-like growth factor I deficiency | 102,396,280(-) | C/G | 3_prime_UTR_variant, genic_downstream_transcript_variant | |
| rs1063599 | uncertain-significance, Insulin-like growth factor I deficiency | 102,398,791(-) | C/A/T | 3_prime_UTR_variant, genic_downstream_transcript_variant | |
| rs1140655 | benign, Insulin-like growth factor I deficiency | 102,397,002(-) | A/T | 3_prime_UTR_variant, genic_downstream_transcript_variant | |
| rs117058953 | uncertain-significance, Insulin-like growth factor I deficiency | 102,398,955(-) | G/A | 3_prime_UTR_variant, genic_downstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2663083 | CNV | deletion | 23128226 |
| esv3309220 | CNV | mobile element insertion | 20981092 |
| esv3445771 | CNV | insertion | 20981092 |
| esv3630590 | CNV | loss | 21293372 |
| esv3630591 | CNV | loss | 21293372 |
| nsv560034 | CNV | loss | 21841781 |
| nsv560035 | CNV | loss | 21841781 |
| nsv819617 | CNV | gain | 19587683 |
| nsv832498 | CNV | gain | 17160897 |
| nsv832499 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
59.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.14;
38.96% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for IGF1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IGF1 Gene
Disorders for IGF1 Gene
(132) MalaCards diseases for IGF1 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| insulin-like growth factor i |
|
|
| pituitary gland disease |
|
|
| acid-labile subunit deficiency |
|
|
| diffuse idiopathic skeletal hyperostosis |
|
|
| osteochondrosis |
|
|
Search IGF1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
IGF1_HUMAN- Insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]: Autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. {ECO:0000269 PubMed:8857020}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for IGF1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Tumor Gene Database
- (TGDB)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for IGF1 Gene
Publications for IGF1 Gene
- Leptin and leptin receptor genotypes and colon cancer: gene-gene and gene-lifestyle interactions. (PMID: 18059035) Slattery ML … Potter JD (International journal of cancer 2008) 3 22 44 58
- Genetic risk factors of bronchopulmonary dysplasia. (PMID: 18614962) Kwinta P … Pietrzyk JJ (Pediatric research 2008) 3 22 44 58
- IGF-II gene region polymorphisms related to exertional muscle damage. (PMID: 17289909) Devaney JM … Clarkson PM (Journal of applied physiology (Bethesda, Md. : 1985) 2007) 3 22 44 58
- Implications for prostate cancer of insulin-like growth factor-I (IGF-I) genetic variation and circulating IGF-I levels. (PMID: 17911177) Johansson M … Kaaks R (The Journal of clinical endocrinology and metabolism 2007) 3 22 44 58
- Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women. (PMID: 16939403) Rivadeneira F … Uitterlinden AG (Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006) 3 22 44 58
Products for IGF1 Gene
- R&D Systems Antibodies for IGF1 (IGF-I)
- R&D Systems Proteins and Enzymes for IGF1 (IGF-I)
- R&D Systems ELISAs and other biochemical assays for IGF1 (IGF-I)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for IGF1
- AM33345PU-N
- AM33345PU-S
- AM33345PU-T
- AM33375SU-N
- AM33375SU-S
- AM50117PU-N
- AM50117PU-S
- AM50117PU-T
- AM50335PU-N
- AM50335PU-S
- AP33340PU-N
- AP33340PU-S
- AP33340PU-T
- BM2079
- BM509
- BP561
- PP1020B1
- PP1020B2
- PP1020P1
- PP1020P2
- TA311185
- TA319033
- TA328347
- TA332383
- TA348004
- TA350696
- TA805728
- TA805748
- CF805748
- TA805792
- CF805792
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for IGF1
- Origene Custom Protein Services for IGF1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for IGF1
- Browse OriGene Inhibitory RNA Products For IGF1
- OriGene qPCR primer pairs and template standards for IGF1
- OriGene qPCR primer pairs for IGF1
- OriGene CRISPR knockouts for IGF1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For IGF1
- GenScript: Next-day shipping of latest version cDNA ORF clones for IGF1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for IGF1
- GenScript Custom Assay Services for IGF1
- GenScript Custom overexpressing Cell Line Services for IGF1
- GenScript: Design CRISPR guide RNA sequences for IGF1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for IGF1
- Sino Biological Human cDNA Clone for IGF1
- Sino Biological Recombinant Proteins for IGF1
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for IGF1
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for IGF1
- Novus Biologicals proteins and lysates for IGF1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for IGF1
- Abcam assays for IGF1
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for IGF1
- Cloud-Clone Corp. Antibodies for IGF1
- Cloud-Clone Corp. Proteins for IGF1
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for IGF1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for IGF1
- Cyagen custom Knockout/knockin (KOKI) mouse models for IGF1
- VectorBuilder custom plasmid, inducible vectors for IGF1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IGF1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 448 available IGF1 Antibodies ranked by validation data
- Compare Top IGF1 Antibodies
- Recommended
- 222 WB Antibodies (anti-human)
- 24 IF (p) Antibodies (anti-human)
- 23 FACS Antibodies (anti-human)
- 17 IHC Antibodies (anti-human)
- 8 RIA Antibodies (anti-human)
- 7 IF Antibodies (anti-human)
- 4 IHC (p) Antibodies (anti-human)
- 4 Neut Antibodies (anti-human)
- 2 IHC (fro) Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 2 InhA Antibodies (anti-human)
- 1 EIA Antibody (anti-human)
- 136 WB Antibodies (anti-mouse)
- 24 IF (p) Antibodies (anti-mouse)
- 22 FACS Antibodies (anti-mouse)
- 5 IF Antibodies (anti-mouse)
- 4 Neut Antibodies (anti-mouse)
- 2 IHC (p) Antibodies (anti-mouse)
- 2 InhA Antibodies (anti-mouse)
- 1 IHC Antibody (anti-mouse)
- 1 RIA Antibody (anti-mouse)
- 76 WB Antibodies (anti-rat)
- 24 IF (p) Antibodies (anti-rat)
- 22 FACS Antibodies (anti-rat)
- 5 IF Antibodies (anti-rat)
- 4 Neut Antibodies (anti-rat)
- 2 IP Antibodies (anti-rat)
- 2 InhA Antibodies (anti-rat)
- 1 IHC Antibody (anti-rat)
- 1 IHC (p) Antibody (anti-rat)
- 1 RIA Antibody (anti-rat)
- antibodies-online: Search results for 183 available IGF1 Elisa Kits ranked by validation data
- Compare Top IGF1 Elisa Kits
- Recommended
- 1 All Species ELISA Kit
- 12 Chicken ELISA Kits
- 16 Cow (Bovine) ELISA Kits
- 1 Deer ELISA Kit
- 10 Dog (Canine) ELISA Kits
- 1 Duck ELISA Kit
- 1 Fish ELISA Kit
- 5 Goat ELISA Kits
- 5 Guinea Pig ELISA Kits
- 1 Hamster ELISA Kit
- 3 Horse (Equine) ELISA Kits
- 31 Human ELISA Kits
- 7 Monkey ELISA Kits
- 38 Mouse (Murine) ELISA Kits
- 13 Pig (Porcine) ELISA Kits
- 11 Rabbit ELISA Kits
- 28 Rat (Rattus) ELISA Kits
- 5 Sheep (Ovine) ELISA Kits
- 1 Turkey ELISA Kit
- 2 Wild boar (Sus scrofa) ELISA Kits
- antibodies-online: Search results for 170 available IGF1 Proteins ranked by validation data
- Compare Top IGF1 Proteins
- GeneTex IGF1 antibody for IGF1
- GeneTex Proteins for IGF1
- ViGene Biosciences adenoviral particle packaged cDNA for IGF1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for IGF1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for IGF1 gene
- Search ViGene Biosciences for IGF1
- Santa Cruz Biotechnology (SCBT) Antibodies for IGF1
- Search Santa Cruz Biotechnology (SCBT) for IGF1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for IGF1
- Horizon Cell Lines for IGF1
- genomics-online: cdna clones - Search results for 235 available IGF1 gene related products
- Overview of 235 available IGF1 gene related products
- Recommended