Search (homepage)
GeneCards Guide
Suite
- GeneALaCart
- GeneDecks
- GeneIP
- GeneNote
- GeneAnnot
- GeneLoc
- GeneTide
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
Mirror sites
User Feedback

Advanced Search (alpha)

IGF1 Gene

protein-coding GIFtS: 69

GC12M102748

insulin-like growth factor 1 (somatomedin C)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

User Feedback

Aliases & Descriptions
insulin-like growth factor 1 (somatomedin C)¹ ²		somatomedin-C²
IGF1A¹ ²		insulin-like growth factor IB²
Mechano growth factor² ³		insulin-like growth factor IA²
IGF-IB² ³		IGFI²
IGF-IA² ³		Somatomedin-C³
MGF² ³		IBP1³

External Ids:	HGNC: 5464¹	Entrez Gene: 3479²	Ensembl: ENSG00000017427⁷	UniProtKB: P01343³	UniProtKB: P05019³

Search outside databases for aliases for IGF1 gene

Previous GC identifers: GC12M101888 GC12M101292

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

User Feedback

Entrez Gene summary for IGF1:

The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of

proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a

specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several

transcript variants encoding different isoforms have been found for this gene.

UniProtKB/Swiss-Prot: IGF1B_HUMAN, P05019

Function: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin

but have a much higher growth-promoting activity

summary for IGF1:

Insulin receptors (IRs) and insulin-like growth factor receptors (IGFRs) are formed from two subunits, each

of which is comprised of an extracellular alpha-subunit and a transmembrane beta-subunit with intracellular

tyrosine kinase activity. IR homodimers are activated by insulin and in adults, mediate an increase in

glucose uptake through upregulation of Glut4 expression. Two isoforms of the IR exist; fetal IR-A and adult

IR-B. IGF1R homodimers are activated by IGF-I and IGF-II and mediate pre- and postnatal growth. IGF2R

sequesters IGF-II and acts to regulate its levels. IR-IGF1R heterodimers exist and, like IGF1R homodimers,

are activated by IGF-I and IGF-II. IRs and IGFRs mediate their intracellular actions through the PI 3-K and

RAS/RAF/MAPK signaling pathways and downstream effectors include mTOR, p70 S6 kinase, ERK and JNK. Many

tumors have altered expression of IGF1R and its ligands and this constitutes an early, possible initiating,

event in tumorigenesis. Decreases in IR signaling causing insulin resistance is a major component in the

development of type 2 diabetes and congenital mutations in the IR can cause the fatal Donohue syndrome.

Gene Wiki entry for IGF1 (Insulin-like growth factor 1)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC and Ensembl (release 56), Regulatory elements and Epigenetics data according to SABiosciences)
About This Section

User Feedback

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the IGF1 gene upstream (promoter) region

:
SRF C/EBPbeta NF-kappaB1 NF-kappaB STAT5B GR-alpha GR-beta STAT5A FOXF2 NF-1

Epigenetics:

Search SABiosciences Methyl-Profiler DNA Methylation qPCR Primer Assays for IGF1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q22-q23 Ensembl cytogenetic band: 12q23.2 HGNC cytogenetic band: 12q23.2

IGF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure

GeneLoc location for GC12M102748: view genomic region (about GC identifiers)

Start:	102,789,645 bp from pter
End:	102,874,423 bp from pter
Size:	84,779 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000012.11 NT_029419.12

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene, Novus Biologicals, and/or Sino Biological,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 May 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abnova, OriGene, Novus Biologicals, and/or Epitomics)
About This Section

User Feedback

UniProtKB/Swiss-Prot: IGF1A_HUMAN, P01343 (See protein sequence)

Recommended Name: Insulin-like growth factor IA precursor

Size: 153 amino acids; 17026 Da

Subcellular location: Secreted

PDB structures from and Proteopedia :

1B9G (3D)

1GZR (3D)

1GZY (3D)

1GZZ (3D)

1H02 (3D)

1H59 (3D)

1IMX (3D)

1TGR (3D)

2GF1 (3D)

3GF1 (3D)

Alternative splicing: 2 isoforms: P01343-1 P05019-1

UniProtKB/Swiss-Prot: IGF1B_HUMAN, P05019 (See protein sequence)

Recommended Name: Insulin-like growth factor IB precursor

Size: 195 amino acids; 21841 Da

Subcellular location: Secreted

PDB structures from and Proteopedia :

1BQT (3D)

1GF1 (3D)

1PMX (3D)

1WQJ (3D)

2DSP (3D)

2DSQ (3D)

2DSR (3D)

3LRI (3D)

Secondary accessions: B2RWM7

Alternative splicing: 2 isoforms: P05019-1 P01343-1

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (4 alternative transcripts):

NP_000609.1 NP_001104753.1 NP_001104754.1 NP_001104755.1

ENSEMBL proteins:

ENSP00000337612 ENSP00000302665 ENSP00000376638 ENSP00000416811 ENSP00000376637 ENSP00000394999

ENSP00000376639

Human Recombinant Proteins

	Millipore Purified and/or Recombinant IGF1 (P01343, P05019) Protein
	Sigma-Aldrich Proteins and CompoZr ZFN for IGF1
	R&D Systems Recombinant & Natural Proteins for IGF1 (IGF-I)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	HuPro® and/or Recombinant Proteins from Abnova for IGF1
	Origene Purified Recombinant Human Protein: IGF1
	Novus Biologicals Proteins for IGF1
	Novus Biologicals Lysate for IGF1
	Browse Sino Biological Recombinant Proteins

4 Gene Ontology (GO) cellular component terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	NAS	14718574
GO:0005615	extracellular space	IDA	7188854 17119061
GO:0016942	insulin-like growth factor binding protein complex	IC	10766744
GO:0031093	platelet alpha granule lumen	EXP	2752154

About this table

IGF1 for ontologies About GeneDecksing

Antibodies for IGF1:

	Millipore Mono- and Polyclonal Antibodies for the study of IGF1
	Sigma-Aldrich Antibodies for IGF1
	R&D Systems Antibodies for IGF1 (IGF-I)
	Cell Signaling Technology (CST) Antibodies for IGF1 (IGF-1Rbeta)
	Monoclonal and Polyclonal Antibodies from Abnova (IGF1)
	Browse Origene Antibodies
	Novus Biologicals Antibodies for IGF1
	Browse antibodies at Epitomics

Assays for IGF1:

	Millipore Kits and Assays for the Analysis of IGF1
	Browse ELISAs at Sigma-Aldrich
	R&D Systems ELISAs for IGF1 (IGF-I)
	Browse Enzo Life Sciences for kits & assays

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

User Feedback

IGF1 for domains About GeneDecksing

1 InterPro domain/family:

IPR016179 Insulin-like

Graphical View of Domain Structure for InterPro Entry P01343

Graphical View of Domain Structure for InterPro Entry P05019

ProtoNet protein and cluster: P01343

1 Blocks protein family: IPB004825 Insulin/IGF/relaxin

UniProtKB/Swiss-Prot: IGF1A_HUMAN, P01343

Similarity: Belongs to the insulin family

UniProtKB/Swiss-Prot: IGF1B_HUMAN, P05019

Similarity: Belongs to the insulin family

(According to MGI May 08 2010, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, Abnova, siRNAs from Applied Biosystems, Sigma-Aldrich, Clones from Millipore, Sigma-Aldrich, OriGene, Sino Biological, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene.)
About This Section

User Feedback

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (IGF1)
		Origene 29mer shRNA kits in GFP-retroviral vector (see all 4): IGF1 Origene shRNA RFP (see all 4): IGF1 Origene basic RS shRNA (see all 4): IGF1
		Applied Biosystems Silencer® siRNAs for IGF1
		Sigma-Aldrich siRNA Panels and siRNA for IGF1 Sigma-Aldrich shRNA Panels and shRNA for IGF1 Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clones for the Expression of Recombinant Proteins Available from Millipore
		Browse iPSC Reprogramming Factors at Sigma-Aldrich
		Origene GFP tagged cDNA clones in CMV expression vector (see all 4): IGF1 Origene Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): IGF1 Origene untagged cDNA clones in CMV expression vector (see all 6): IGF1
		Browse Sino Biological Human cDNA Clones

UniProtKB/Swiss-Prot: IGF1A_HUMAN, P01343

Function: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin

but have a much higher growth-promoting activity

UniProtKB/Swiss-Prot: IGF1B_HUMAN, P05019

Function: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin

but have a much higher growth-promoting activity

Genatlas biochemistry entry for IGF1:

insulin-like growth factor 1,expressed in liver,regulator of somatic growth and cellular proliferation,inducer of the

phosphatidylinositol 3-kinase survival pathway through activation of AKT1,AKT2,inhibited by TNF in its neuroprotective

role,also inducer of calcineurin mediated signaling and activation of GATA2,associated with intrauterine growth

retardation and severe short stature in a patient carrying a homozygous deletion of IGF1

5 Gene Ontology (GO) molecular function terms (GO ID links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005158	insulin receptor binding	IPI	8452530
GO:0005159	insulin-like growth factor receptor binding	TAS	10749889
GO:0005179	hormone activity	IEA	--
GO:0005515	protein binding	IPI	10766744
GO:0008083	growth factor activity	IEA	--

About this table

IGF1 for ontologies About GeneDecksing

Animal Models: 15/17 MGI mutant phenotypes (inferred from 7 alleles) (MGI details for Igf1) (see all 17 ):

cardiovascular system	cellular	growth/size	hearing/vestibular/ear	homeostasis/metabolism
lethality-postnatal	lethality-prenatal/perinatal	life span-post-weaning/aging	limbs/digits/tail	muscle
nervous system	normal	reproductive system	respiratory system	skeleton

IGF1 for phenotypes About GeneDecksing

(Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, Applied Biosystems GeneAssist, KEGG and/or UniProtKB, (map by GeneGo),
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene).
About This Section

User Feedback

IGF1 for pathways About GeneDecksing

5/10 Millipore Pathways for IGF1 (see all 10 )

	Transcription Androgen Receptor nuclear signaling
	Signal transduction PTEN pathway
	Development Ligand-independent activation of ESR1 and ESR2
	G-protein signaling RhoA regulation pathway
	Development IGF-RI signaling

5/16 Sigma-Aldrich "Your Favorite Gene" Pathways for IGF1 (Your Favorite Gene powered by Ingenuity) (see all 16 )

	Glioblastoma Multiforme Signaling
	RhoA Signaling
	Growth Hormone Signaling
	Glioma Signaling
	Axonal Guidance Signaling

5/53 GeneAssist Pathways for IGF1 (see all 53 )

	Glioma Invasiveness
	Nanog in Mammalian ESC Pluripotency
	ERK Signaling
	CREB Pathway
	Telomerase Components in Cell Signaling

5/13 Kegg Pathways (Kegg details for IGF1) (see all 13 ):

	hsa04114 Oocyte meiosis
	hsa04115 p53 signaling pathway
	hsa04150 mTOR signaling pathway
	hsa04510 Focal adhesion
	hsa04730 Long-term depression

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for IGF1

5/81 Interacting proteins for IGF1 (ENSP00000302665³ P05019²) via UniProtKB, MINT, and/or STRING (see all 81 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
IGFBP3	ENSP00000370473³	STRING: ENSP00000370473
IGFBP4	ENSP00000269593³	STRING: ENSP00000269593
IGFBP5	ENSP00000233813³	STRING: ENSP00000233813
IGFBP1	ENSP00000275525³	STRING: ENSP00000275525
IGF1R	ENSP00000268035³	STRING: ENSP00000268035

About this table

5/48 Gene Ontology (GO) biological process terms (GO ID links to tree view) (see all 48 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001501	skeletal system development	TAS	10448861
GO:0006260	DNA replication	TAS	10766744
GO:0006916	anti-apoptosis	IDA	16942485
GO:0006928	cellular component movement	TAS	10766744
GO:0007165	signal transduction	TAS	10448861

About this table

IGF1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

User Feedback

IGF1 for compounds About GeneDecksing

Enzo Life Sciences drugs & compounds for IGF1

Sigma-Aldrich Small Molecules for IGF1:

Small Molecule - Inhibitor

Compounds for IGF1 available from Tocris Bioscience

Compound	Action	CAS number
Demethylasterriquinone B1	Selective insulin RTK activator	[78860-34-1]
PQ 401	IGF1R inhibitor	[196868-63-0]

About this table

10/1260 Novoseek chemical compound relationships for IGF1 gene (see all 1260 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
pegvisomant	100.00	191	17077131 (7), 20009494 (5), 18498055 (5), 17289896 (5) (see all 100)
octreotide	100.00	434	1547711 (8), 7535670 (7), 15994747 (7), 19141605 (6) (see all 100)
estradiol	91.94	885	9814485 (10), 9626134 (8), 7704427 (6), 2171908 (6) (see all 100)
dehydroepiandrosterone sulfate	86.93	280	10698044 (13), 17381481 (9), 10821876 (8), 9100552 (7) (see all 100)
lanreotide	82.32	116	8921789 (5), 10090136 (5), 15789272 (4), 10468985 (4) (see all 66)
ly294002	79.59	190	19855934 (4), 11228049 (4), 9139803 (3), 9838099 (2) (see all 100)
wortmannin	55.48	185	19855934 (4), 9139803 (3), 7615073 (3), 12032677 (3) (see all 100)
testosterone	39.95	1149	7486812 (10), 1315260 (10), 15240605 (8), 10514558 (8) (see all 100)
pd 98059	35.13	136	9261137 (4), 19937471 (4), 12843192 (4), 11228049 (4) (see all 100)
phosphatidylinositol	32.52	377	8666135 (6), 9886492 (5), 1311242 (5), 11316733 (4) (see all 100)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 223 Homo sapiens; Apr 2 2010) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Millipore and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene, microRNA from SABiosciences,
Tagged/untagged cDNA clones from OriGene, Primers from OriGene and/or SABiosciences,
Expression Assays from Applied Biosystems)
About This Section

User Feedback

Inhib. RNA:		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (IGF1)
		Applied Biosystems Silencer® siRNAs: NM_000618 NM_001111283 NM_001111284 NM_001111285
		Origene 29mer shRNA kits in GFP-retroviral vector (see all 4): IGF1 Origene shRNA RFP (see all 4): IGF1 Origene basic RS shRNA (see all 4): IGF1
		Sigma-Aldrich siRNA Panels and siRNA for IGF1 Sigma-Aldrich shRNA Panels and shRNA for IGF1 Explore Sigma-Aldrich super-pooled esiRNAs

microRNA:		10/24 SABiosciences microRNAs that regulate IGF1 (see all 24 ):
		hsa-miR-320a hsa-miR-142-5p hsa-miR-495 hsa-miR-496 hsa-miR-29c hsa-miR-29a hsa-miR-30a* hsa-miR-486-5p hsa-miR-186 hsa-miR-613

Assays:

Applied Biosystems TaqMan® Gene Expression Assays:

NM_000618 NM_001111283 NM_001111284 NM_001111285

Clones:

Origene GFP tagged cDNA clones in CMV expression vector (see all 4): IGF1
Origene Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): IGF1
Origene untagged cDNA clones in CMV expression vector (see all 6): IGF1

Primers:		Origene genome-wide validated SYBR primer pairs: IGF1
		SABiosciences RT2 qPCR Primer Assay for IGF1: PPH00167A

REFSEQ mRNAs for IGF1 gene (4 alternative transcripts):

NM_000618.3 NM_001111283.1 NM_001111284.1 NM_001111285.1

Additional cDNA sequence:

AB209184.1 AK312231.1 BC148266.1 BC152321.1 CR541861.1 M11568.1 M27544.1 M29644.1

M37484.1 U40870.1 X00173.1 X56773.1 X56774.1 X57025.1

7 DOTS entries:

DT.454558 DT.92461093 DT.100680034 DT.75105093 DT.95275111 DT.100659724 DT.40304132

24/161 AceView cDNA sequences (see all 161 ):

AA703492 X56774 BE044197 BF222309 AA640354 AW517507 AW102819 AU118321

BQ024203 AI457887 BF445871 BF589728 AW204378 BQ773809 M37484 AI248089

AA580109 BQ787248 U40870 AA723451 CR541861 AL709516 AI478804 H88012

highest scoring ESTs for IGF1:

X57025 AA041267 AA128498 AL599807 AL603526 AL708718 AL709516 AL710591 AW022660 BF091004

Unigene Cluster for IGF1:

Insulin-like growth factor 1 (somatomedin C)

Hs.160562 [show with all ESTs]

Unigene Representative Sequence: NM_001111283

GeneLoc Exon Structure

8 Ensembl transcripts including schematic representations:

ENST00000337514 ENST00000307046 ENST00000392905 ENST00000424202 ENST00000392904 ENST00000481539

ENST00000456098 ENST00000392906

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 223 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems, Primers from OriGene and/or SABiosciences )
About This Section

User Feedback

IGF1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for IGF1

¹ / ² / ³

13 probe-sets matching IGF1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1975_s_at²^{, 3}	U95-A	1	1.00	1.00	0.80	1.16	X03563	0.20	1.00	0.72	1
1501_at²^{, 3}	U95-A	1	0.88	1.00	0.96	1.08	X57025	1.00	1.00	1.00	1
64305_s_at²^{, 3}	U95-C	1	0.88	1.00	0.38	0.95	AW022660	0.80	1.00	0.91	1
38737_at²^{, 3}	U95-A	1	0.75	1.00	0.97	0.85	M14156	0.20	1.00	0.72	1
1625_at²^{, 3}	U95-A	1	0.62	1.00	0.82	0.39	HG2309-HT2405	0.20	1.00	0.72	1
211577_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	M37484	0.60	1.00	0.82	1
209540_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AU144912	0.40	1.00	0.76	1
209542_x_at²^{, 3}	U133-A	1	0.91	1.00	--	--	M29644	0.80	1.00	0.91	1
209541_at²^{, 3}	U133-A	1	0.73	1.00	--	--	AI972496	0.20	1.00	0.72	1
211577_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
209540_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
209542_x_at²	U133Plus2	1	0.91	1.00	--	--	--	--	--	--	--
209541_at²	U133Plus2	1	0.73	1.00	--	--	--	--	--	--	--

About this table

IGF1 for expression About GeneDecksing

Data from Genenote (Publications) and GNF BioGPS
About these images

About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.160562

Expression variation in blood from EXPOLDB for IGF1

Primers:		Origene genome-wide validated SYBR primer pairs: IGF1
		SABiosciences RT2 qPCR Primer Assay for IGF1: PPH00167A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI May 08 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

User Feedback

Orthologs for IGF1 gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	IGF1¹	--	insulin-like growth factor 1 (somatomedin C)	93.68(n) 97.39(a)	610255 XM_848024.1 XP_853117.1
chimpanzee (Pan troglodytes)	IGF1¹	--	insulin-like growth factor 1 (somatomedin C)	100(n) 100(a)	741055 XM_001156521.1 XP_001156521.1
cow (Bos taurus)	IGF1¹	--	insulin-like growth factor 1 (somatomedin C)	93.46(n) 96.08(a)	281239 XM_001251168.1 XP_001251169.1
rat (Rattus norvegicus)	Igf1¹	--	insulin-like growth factor 1	87.93(n) 92.91(a)	24482 NM_178866.2 NP_849197.1
mouse (Mus musculus)	Igf1^{1, 5}	10 (48.00 cM)⁵	insulin-like growth factor 1^{1, 5}	85.47(n)¹ 89.74(a)¹	16000¹ NM_184052.2¹ NP_908941.1¹ AA544955⁵ AF440694⁵ (see all 21)

About this table Species with no ortholog for IGF1

ENSEMBL Gene Tree for IGF1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

User Feedback

Paralogs for IGF1 gene

IGF2²

IGF1 for paralogs About GeneDecksing

(SNPs according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Genotyping Reagents from Applied Biosystems)
About This Section

User Feedback

10/724 NCBI SNPs in IGF1 are shown (see all 724 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 258)

AB	SNP ID	Valid	Chr 12 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Related Data				Allele Frequencies
				--	--	--		--	--			--
	rs6220^1,2	C,F,O,A,H	102794515(+)	`TAAACA/GAGGTT`	3	--	ut3¹		20	MN NA EA NS WA	1250
	rs35767^1,2	C,F,O,A,H	99935100(-)	`TCATGC/TGGAAA`	3	--	ng5¹		31	MN NS EA NA	3228
	rs5742612^1,2	C,F,A,H	99934397(-)	`ACACCT/CCTCAC`	3	--	ng5¹		35	NS NA MN EA WA	3074
	rs6214^1,2	C,F,A,H	102793569(-)	`TTAACG/ATGTTT`	3	--	ut3¹ ese³		28	MN NS EA NA WA	2393
	rs11829707^1,2	C,F,A,H	99934659(+)	`AACCtG/Ctgtgt`	3	--	ng5¹		6	NS EA WA NA	472
--	rs11829693^1,2	C,F,A,H	99934788(+)	`CCTCTC/TGAGGG`	3	--	ng5¹		10	NS NA WA	859
	rs6219^1,2	C,F,O,A	102790192(-)	`CTCAAA/GCTGTC`	3	--	ut3¹ ese³		23	MN NS EA NA	1921
	rs5742711^1,2	C,F,H	102791083(-)	`CTGCCT/GCAGAA`	3	--	ut3¹ ese³		7	NS EA	680
	rs5742714^1,2	C,F,A	102789852(-)	`ATTCTG/CATTGT`	3	--	ut3¹		16	NS MN EA NA WA	1288
	rs3730205^1,2	C,F,H	102791749(-)	`AACTAT/CAGGCT`	3	--	ut3¹		6	NS EA	504

About this table

HapMap Linkage Disequilibrium images for IGF1 (up to first 250kb)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for IGF1
1 Indel: 58548

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

User Feedback

IGF1 for disorders About GeneDecksing

OMIM: 147440 disorders: 608747

UniProtKB/Swiss-Prot: IGF1B_HUMAN, P05019

Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1

deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental

retardation

Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) [MIM:608747]. IGF1

deficiency is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental

retardation

10/1676 Novoseek disease relationships for IGF1 gene (see all 1676 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
acromegaly	100.00	813	17575366 (7), 12100070 (7), 17047383 (6), 9231047 (5) (see all 100)
deficiency; growth hormone	100.00	195	9272100 (7), 9078817 (6), 19381505 (6), 15583470 (6) (see all 100)
laron syndrome	100.00	209	19117781 (5), 9509072 (4), 9030966 (4), 8265812 (4) (see all 100)
gh deficiency	100.00	570	9801991 (13), 9689828 (8), 10941424 (8), 9042120 (7) (see all 100)
igf-i resistance	100.00	67	8809343 (3), 15476454 (3), 10198399 (3), 8964861 (2) (see all 52)
dwarf	64.22	228	15888324 (6), 9578506 (4), 9176194 (4), 9000465 (4) (see all 100)
idiopathic short stature	60.43	83	11966736 (8), 10848878 (8), 14725676 (4), 11155089 (4) (see all 50)
short stature	57.87	181	9740270 (3), 9713560 (3), 3331010 (3), 2626840 (3) (see all 100)
growth failure	42.85	93	7794630 (3), 2591131 (3), 2155253 (2), 19717008 (2) (see all 80)
catabolic state	41.48	53	16500651 (3), 17622956 (2), 1371669 (2), 9817989 (1) (see all 49)

About this table

Locus Specific Mutation Databases: IGF1
Human Gene Mutation Database: IGF1
Genetic Association Database: IGF1
Human Genome Epidemiology Navigator: IGF1 (236 documents)
Tumor Gene Database: IGF1

(Possibly Related Articles in Doctor's Guide)
About This Section

User Feedback

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

User Feedback

10/8091 PubMed articles for IGF1 gene (see all 8091 ):

A polymorphism in the IGF-I gene influences the age-related decline in circulating total IGF-I levels. (PubMed id 12590635)^{1, 3, 6} Rietveld I....Lamberts S.W. (2003)
IGF1 (CA)19 repeat and IGFBP3 -202 A/C genotypes and the risk of prostate cancer in Black and White men. (PubMed id 15734965)^{1, 3, 6} Schildkraut J.M....Walther P.J. (2005)
Polymorphisms in the IGF-1 and IGFBP 3 promoter and the risk of breast cancer. (PubMed id 15986122)^{1, 3, 6} Wagner K....Forsti A. (2005)
Insulin-like growth factor I gene promoter polymorphism, collagen type II alpha1 (COL2A1) gene, and the prevalence of radiographic osteoarthritis: the Rotterdam Study. (PubMed id 15082485)^{1, 3, 6} Zhai G....van Duijn C.M. (2004)
A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects. (PubMed id 15302607)^{1, 3, 6} Nielsen E.M....Pedersen O. (2004)
Insulin-like growth factor polymorphisms and colorectal cancer risk. (PubMed id 15894673)^{1, 3, 6} Morimoto L.M....Potter J.D. (2005)
An IGF-I promoter polymorphism modifies the relationships between birth weight and risk factors for cardiovascular disease and diabetes at age 36. (PubMed id 15927083)^{1, 3, 6} te Velde S.J....Kemper H.C. (2005)
Analysis of coding and promoter sequences of the IGF-I gene in children with growth disorders presenting with normal level of growth hormone. (PubMed id 14714750)^{1, 3, 6} Obrepalska-Steplowska A....Gozdzicka-Jozefiak A. (2003)
A putative functional polymorphism in the IGF-I gene: association studies with type 2 diabetes, adult height, glucose tolerance, and fetal growth in U.K. populations. (PubMed id 12086966)^{1, 3, 6} Frayling T.M....Ben-Shlomo Y. (2002)
Prostate cancer risk and IRS1, IRS2, IGF1, and INS polymorphisms: strong association of IRS1 G972R variant and cancer risk. (PubMed id 15678496)^{1, 3, 6} Neuhausen S.L....Brothman A.R. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

User Feedback

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

User Feedback

Entrez Gene: 3479	HGNC: 5464	AceView: IGF1	Ensembl:ENSG00000017427	euGenes: HUgn3479
ECgene: IGF1	Kegg: 3479	H-InvDB: IGF1

(According to HUGE)
About This Section

User Feedback

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

User Feedback

Name	Description
ATLAS Chromosomes in Cancer entry for IGF1	Genetics and Cytogenetics in Oncology and Haematology
Mammary Transgene Database entry for IGF1	More genetic and clinical information
NIEHS-SNPs	http://egp.gs.washington.edu/data/igf1/
SHMPD	http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=HLA-DQB1
Wikipedia	http://en.wikipedia.org/wiki/Insulin-like_growth_factor_1
SHMPD	http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=HLA-DQB1

Intellectual Property for IGF1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from XenneX, Inc.)

About This Section

User Feedback

Patent Information for IGF1 gene:

Search GeneIP for patents involving IGF1

GeneCards and IP:

Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Novus Biologicals,
Epitomics, Sigma-Aldrich, R&D Systems, SABiosciences, Millipore, Abnova,
Clones available from OriGene, Sigma-Aldrich, Sino Biological, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

User Feedback

Products for IGF1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for IGF1		Antibodies for IGF1
	Explore super-pooled esiRNAs		Proteins for IGF1
	Lentivirus-delivered shRNAs for IGF1		Small molecules for IGF1
	"Your Favorite Gene" Pathways		Browse ELISAs at Sigma-Aldrich
	Browse iPSC Reprogramming Factors at Sigma-Aldrich		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (IGF1)
	Antibodies (IGF1)
	Chimera RNAi (IGF1)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for IGF1 (IGF-1Rbeta)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector
	Custom immunoassay development

Tocris compounds for IGF1

	Regulatory tfbs in IGF1 upstream (promoter) region
	Search Chromatin IP Primers for IGF1
	Search DNA Methylation qPCR Primer Assays for IGF1
	RT2 qPCR Primer Assay for IGF1
	GNC Network for IGF1
	microRNAs that regulate IGF1

	Drugs for IGF1
	Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	Antibodies for IGF1
	Proteins for IGF1
	Lysates for IGF1

Browse antibodies at Epitomics

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

User Feedback

GeneCards Homepage - Last full update: 20 May 2010 - Incremental updates: 24 May 2010 , 20 Jun 2010

View Random Gene

Category			ACSF3 acyl-CoA synthetase family member 3
GIFtS Group

The GeneCards human gene database gene index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

IGF1 gene at Home site.

hostname: server4.xennexinc.com db build: 72 index build: 72d solr: 1.4

Advanced Search (alpha)

IGF1 Gene

protein-coding GIFtS: 69

Aliases &
Descriptions
for IGF1 gene

Summaries
for IGF1 gene

Genomic Views
for IGF1 gene

Proteins
for IGF1 gene

Protein Domains/
Families
for IGF1 gene

Gene Function
for IGF1 gene

Pathways & Interactions
for IGF1 gene

Drugs & Compounds
for IGF1 gene

Transcripts
for IGF1 gene

Expression
for IGF1 gene

Orthologs
for IGF1 gene

Paralogs
for IGF1 gene

Genomic Variants
for IGF1 gene

Disorders & Mutations
for IGF1 gene

Medical News
for IGF1 gene

Publications
for IGF1 gene

Search for IGF1 gene

Genome Databases showing IGF1 gene

Other Databases showing IGF1 gene

Specialized Databases showing IGF1 gene

Intellectual Property
for IGF1 gene

Services
for IGF1 gene

View Random Gene

beckwith-wiedemann syndrome
diabetic ketoacidosis
small intestinal dysmotility
breast mouse
malformation
slipped femoral capital epiphysis
fibrosis myocardial
skin ulcer
hyperthyroid
h pylori infection
laron syndrome
epilepsies
hypoglycemia nocturnal
apnea
white forelock
nasal polyp
posterior capsule opacification
blood brain barrier defect
hypoglycemia
thanatophoric dysplasia
gastroparesis
diverticulum
adenoviral infection
olfactory neuroblastoma
cardiovascular cancer
adpkd
atopic
osteophyte
sex chromosome abnormalities
low-grade glioma
sclerosis; systemic
chronic inflammatory response
esophageal atresia
MI
post-poliomyelitis syndrome
abuse; hormones
hyperemia
pituitary mass
demineralization; bone
cns malignancy
choline deficiencies
metastasis
seckel syndrome
adenocarcinoma endometrial
combined pregnancy
impaired wound healing
pyloric stenosis, infantile hypertrophic
hypogammaglobulinemia
prostate tumor
graves ophthalmopathy
leishmaniasis visceral
arteritis
rabson-mendenhall syndrome
pyometra
hepatic hemosiderosis
persistent inflammation
renal fibrosis
acute necrotizing pancreatitis
osteoporosis
carnitine deficiency
beta-thalassemia
endocrinopathy
lymphopenia
pituitary incidentaloma
aging; premature
ascites chylous
gonadal dysfunction
esophageal adenocarcinoma
granulosa cell tumor
anemia deficiency iron
gh deficiency
hypoplasia
immune dysfunction
arteriovenous fistula
hypertrophy; ventricular; right
disuse muscle atrophy
benign epithelial tumor
lumbar disc herniation
gammopathy
tsh deficiency
juvenile disease
diabetic polyneuropathies
cystitis interstitial
failure respiratory
kidney functional
renal atrophy
postinfarction
dilatations
strabismus
acidosis metabolic chronic
invasive breast cancer
capillaries; degeneration
neuromuscular disease
ovarian epithelial tumor
systemic mastocytosis
disorder; growth
medullary thyroid carcinoma
dystrophies
lupus erythematosus systemic
chronic heart failure
bone disease
fatty liver
social anxiety
cns disease
central precocious puberty
damage liver
iddm11
brain disease
infertility
growth suppression
gravis; myasthenia
atrophy testicular
fulminant hepatic failure
benign prostatic hypertrophy
NF1
urinary tract tumor
inflammatory disease
adenocarcinoma lung
breast cancer
infarction; myocardial
hypercholesterolemia
antidiuresis
exophthalmos
follicular tumor
cognitive deterioration
tumor promotion
cervical intraepithelial neoplasia
deficiency; manganese
chromosomal aberration
neurofibrillary tangle
growth hormone secreting adenoma
depression endogenous
colonic adenoma
carcinoma; nasopharyngeal
ebv infection
nonfunctioning pituitary adenoma
healing ulcer
burkitt lymphoma
androgen excess
failure; myocardial
mixed cell adenoma
hyperglycemia
cervical cancer
anemia
asbestosis
cancer other
lipodystrophies
hypertrophic obstructive cardiomyopathies
prostatic adenocarcinoma
hepatoblastoma
fibrillation
colitis
idiopathic disease
atypical adenomatous hyperplasia
disorder tendon
disorder; reproductive
plurihormonal adenoma
oedema peripheral
xerostomia
mucosal inflammation
glioma
igf-i resistance
trichinella spiralis infection
angina stable
carbonic anhydrase ii deficiency
steroid-dependent nephrotic syndrome
carcinoma; renal cell
gastrointestinal candidiasis
dysfunction; hypothalamic
cataract diabetic
short bowel syndrome
intracranial tumor
cardiovascular morbidity
ichthyosis
background retinopathy
bladder disease
delayed graft function
secondary infection
histiocytosis; langerhans cell
diabetic macroangiopathy
alagille syndrome
dysplasia; septo-optic
t-all
klinefelter syndrome
hemorrhage; intraventricular
cushing disease
VSD
oa hip
granulomatosis; wegener
disability; physical
complicated pregnancy
encephalopathies
leukemia myeloid
borderline hypertension
malnutrition, secondary
granuloma
metastatic ovarian carcinoma
glomerulonephritis
hypertension; renovascular
fibromyalgia
glucose metabolism disorder
von willebrand
delivery preterm
galactorrhea
microalbuminuria
arrest cardiac
brca1 mutation
hematopoietic cell proliferation
pleural mesothelioma
childhood leukemia
pancreatic ductal adenocarcinoma
demented
fetal alcohol syndrome
depletion; potassium
colorectal villous adenoma
tendinosis
fat redistribution
hyperthyroidism
coronary stenosis
oa knee
HIE
adrenarche; premature
obstruction
lymphoid malignancy
diabetic microangiopathies
dupuytrens disease
low-grade squamous intraepithelial lesion
hyperestrogenism
nevi
ductal hyperplasia
precancerous lesions
branchial; cartilage
anti-thyroid antibodies
myxoma
dysgenesis; gonadal
familial dysautonomia
colorectal adenoma
hyperplasia; thyroid
breast cancer stage ii
nonproliferative retinopathy
gynecomastia
fibrous histiocytoma
pheochromocytoma
hashimoto thyroiditis
fibrosarcoma
celiac disease
ighd ii
vitamin d deficiencies
hypercalciuria
mesodermal mixed tumor
lewis lung carcinoma
testotoxicosis
malignant glioma
ataxia telangiectasia
acute intermittent porphyria
hiv disease progression
HI
telangiectasia
response, acute phase
skin tumor
fetal growth abnormality
schistosomiasis mansoni
myopathy steroid
hyperplasia
atrial septal defect
connective tissue disease
insulin resistant diabetes mellitus
hearing loss sensorineural
neovascular glaucoma
gliosis
infarct
auricular; thrombosis
underdevelopment
estrogen deficiency
leukemia
congenital diaphragmatic hernia
pathogeneses
gonadotroph adenoma
rem sleep deprivation
hydatidiform mole
compensatory hypertrophy
contracture
herniation
cognitive deficit
arteriosclerosis
bronchitis chronic
gastric ulcer
chronic metabolic disorder
spinal muscular atrophy
dysfunction kidney
prognathism
renal failure acute ischemic
dysmotility
nitrogen; retention
variable number tandem repeat
enterocolitis
polycystic kidney disease
carcinoma gallbladder
premature newborn
angiomyolipoma
CAD
cardiomyopathies
mccune-albright syndrome
hutchinson-gilford progeria syndrome
deficiency; protein
persistent infection
pituitary macroadenoma
complications; postoperative
amenorrhoea
disease; fibroid
dementia
fistula
infection viral
macular edema
microsatellite instability
diabetic peripheral neuropathy
empty sella
myelomeningocele
tumor enlargement
hyperbilirubinemia neonatal
osteochondrosis
sclerosis
iugr
glomerular disease
hyperlipidemia
teratocarcinoma
melanoma metastatic
embryo death
autoimmunities
hiv-lipodystrophy
diabetes; type 2
severe hypothyroidism
catecholamine; secretion
jaundice neonatal
asthma
acidosis; renal
seminoma
papilloma skin
dysfunction; sexual
myopia
bulimia
obstructive uropathy
basal cell hyperplasia
jaundice
acidosis metabolic
cardiovascular risk factor
neurological disorder
staph
scleroderma
acromicria
gram-negative; sepsis
malnutrition
growth hormone treatment
claudication
proteinuria
sickle cell disease
immunodeficiency
pseudohypoparathyroidism
pre-diabetic
cancer recurrence
androgen insensitivity syndrome
change; cognitive
death neonatal
sarcoma
deficiency; iron
disease; ischemic heart
hypersensitivities
carotid atherosclerosis
necrosis; tubular
mood disorder
androgenization
stemi
major depression
genomic instabilities
encephalomyelitis
hydatid cyst
invasive carcinoma
chronic inflammatory disease
partial lipodystrophy
prolactinoma
lead line
bacterial infection
liposarcoma
crohn
colorectal polyp
deficiency; endocrine
infantile neuronal ceroid lipofuscinosis
cerebral palsy
endometrial hypoplasia
prolactin deficiency
nephrosclerosis
calcification
chronic hepatitis c
carcinoid
epiretinal membrane
central hypogonadism
premature pubarche
acute inflammatory response
CKD
muscle fiber hypertrophy
mitochondrial damage
hypertension portal
complications; vascular
toxic nodular goiter
tumorigenicity
adenomatous hyperplasia
x-linked recessive
iodine deficiency goiter
septicemia
dysfunction testicular
chronic hepatitis, b virus
hypocalciuria
limb reduction defect
AD
pathological angiogenesis
alcoholic myopathy
beta-galactosidase deficiency
infarction; renal
restenosis
hyperplasia; prostate
leukemia lymphoid
infectious
galactosemia
low-renin essential hypertension
reactive hyperemia
ovarian tumor
mesangial proliferation
atrophy; seminal vesicle
type ii obese diabetic
myxedema
androgenetic alopecia
syringes
bronchogenic carcinoma
bell palsies
mild pre-eclampsia
global developmental delay
benign ovarian tumor
pelvic kidney
endometrioma
cartilage; loss
major; thalassemia
neurodegenerative disease
facial paralysis
hypertrophy; ventricular; left
type i endometrial adenocarcinoma
meckel syndrome
estrogenic effect
intestinal mucosal atrophy
histiocytoma
abnormal fetuses
lesion; nerve
ovarian cancer
shope fibroma
breast cyst
prion disease
ALL
epithelial proliferation
leiomyoma
hepatic schistosomiasis
atherogenesis
DMD
osteoporosis postmenopausal
aplasia bone marrow
fibrosis liver
bladder hypertrophy
exercise proteinuria
compensatory hyperinsulinemia
sclc
azotemia
mental retardation
bulimia nervosa
cell injury
degenerative disease
lymphoma, t-cell
copper deficiency
thyrotoxicosis
neoplastic transformation
growth delay
prostatic disease
18 trisomy
diabetic vascular complication
lesion; periodontal
malnutrition; protein
morphea
glycogen deposition
colon cancer
tetanus
PID
thalassemia
BBS
astrocytoma
intestinal infection
contralateral breast cancer
dysfunction; endometrial
cardiovascular abnormalities
diabetic eye disease
labor preterm
distress syndrome; respiratory
thyroid cancer
PBC
inflammation, allergic
abortion (spontaneous)
albino
chronic viral hepatitis
motor neuropathy
pituitary disease
hypothalamic disorder
myonecrosis
smooth muscle hypertrophy
acute cerebral ischemia
cerebellar degeneration
perivascular tumor
ards
mitral regurgitation
fenestration
ovarian cystic disease
aromatase activity, increased
arthritis chronic
immaturity
airway obstruction upper
compensated cirrhosis
adrenocortical carcinoma
ovarian endometriosis
myocardial necrosis
alkalosis metabolic
neuropathy
stillbirth
liver dysfunction
mitochondrial myopathies
aneurysmal bone cyst
gastritis
age-related cognitive decline
rabies
deficiency; selenium
fluid retention
frozen shoulder
hypersensitivity, other
central retinal vein occlusion
brcax
cerebrovascular disease
isolated gh deficiency
leukemogenesis
leiomyosarcoma
vascular disease
spontaneous hypoglycemia
choriocarcinoma
DISH
steatorrhea
primary congenital hypothyroidism
nphp1
microangiopathy
sepsis
ischemia retinal
malaria
erythroleukemia
transient ischemia
differentiated thyroid carcinoma
diabetic retinopathy proliferative
atrophic endometrium
hyperparathyroidism secondary
damage; renal
amyloidosis
childhood celiac disease
increased; permeability
apnea; sleep
bone loss
scotoma
disorder personality
squamous intraepithelial lesion
somatic mutation
shock
cerebral infarction
diabetic cardiomyopathy
pneumoniae
dominant-negative mutant
fibroma
colorectal cancer
epilepsy temporal lobe
hnscc
aortocaval fistula
alport syndrome
hypertension
renal impairment
arrhythmia
cysts
deciduoma
idiopathic osteoporosis
diabetes mellitus (gestational)
pancreatic islet hyperplasia
polyneuropathies
innate immune response
extravasation
testicular disorder
igf1 deficiency
nodule; thyroid
failure; ventricular; left
incipient diabetic nephropathy
preeclampsia
huntington disease
astrocytoma, low grade
deficiency; folate
neuropathy sensory
cutaneous leishmaniasis
gvhd
hypothalamic amenorrhea
gastric cancer
barrett esophagus
chronic ulcer
melanoma
SRS
inflammatory joint disease
tumor progression
carotid stenosis
keloids
skeletal dysplasia
ankylosis
disease; parasitic
high-grade prostatic intraepithelial neoplasia
hypertensive heart disease
anovulatory
reactive hyperplasia
disease; inflammatory bowel
eruption
chronic rhinosinusitis
fetal stress
human immunodeficiency virus
leydig cell tumor
metabolic syndrome x
rickets
cytopathic effect
thin glomerular basement membrane disease
neurofibromatosis
meningioma
gout
CFS
meningothelial meningioma
pancreatic tumor
infection urinary tract
leukodystrophies
metabolic bone disease
secondary hyperthyroidism
acute alcohol intoxication
breast disease
adrenocortical hyperplasia
metastatic prostate cancer
dyschondroplasia
hypoglycemia (neonatal)
angina unstable
jaundice obstructive
orphan disease
polio
fold; skin
obstructive sleep apnea
callus formation delayed
disuse osteoporosis
resorption, root
compression fracture
dysfunction; gland
osteopetrosis
focal hyperplasia
down syndrome
brain tumor malignant
adenoma thyroid
pulmonary sarcoidosis
complex atypical endometrial hyperplasia
colitis ulcerative
macroangiopathy
parathyroid adenoma
macular hole
phyllodes tumor
nsclc
primary tumor
lesion; vascular
diabetic retinopathies
nephrotic syndrome
hereditary cerebellar ataxia
nephropathy obstructive
tumor necrosis
rhabdomyosarcoma
break, double-strand dna
axonal neuropathy
multinodular goiter
preterm infant
cyst benign
testosterone deficiency
hyperphosphatemia
ataxia
cor pulmonale
acute promyelocytic leukemia
polyp
ulcer
MS
cardiomyopathy dilated
breast cancer stage i
pediatric tumor
meningococcal sepsis
progressive bulbar palsies
osteodystrophy renal
SARS
cirrhosis; nutritional
circulation; fetal
cns tumor
somatotroph adenoma
chronic leukemia
lymphocytic infiltration
aids wasting syndrome
anovulation
ischemia; spinal cord
renal ischemia
cachexia; cancer
retinal vascular
pulmonic stenosis
oesophageal
failure; renal
chronic gvhd
endocrine tumor
shigellosis
concentric lvh
dysfunction; myocardial
neurotrophic keratopathy
AMD
disease; respiratory
tendinitis
myelopathies
hyperparathyroidism
edema retinal
diabetes mellitus
systemic juvenile rheumatoid arthritis
sarcocystosis
damage; vascular
carbohydrate; intolerance
oligozoospermia
pregnancy early
blue sclera
alcohol withdrawal
HL
embryopathies
acute renal insufficiencies
mesothelioma
congenital deficiencies
syndrome, zollinger-ellison
fetal malnutrition
atrophy optic
syndrome; turner
lupus nephritis
cancer, benign
impairment; memory
21-hydroxylase deficiency
rare disorder
dcis
metabolic disturbance
acute coronary syndrome
skin carcinogenesis
nephritis
block incomplete
acute myocardial infarction
dystrophy; myotonic
hypertrophy; tonsillar
SAH
hypoxic
oral submucous fibrosis
cellular stress
complications; endocrine
insulin-resistant diabetes
macroprolactinoma
biliary obstruction
hemodynamic instability
cholestasis
infection; wound
brain; ischemic
anabolic steroids
coronary atherosclerosis
adenoma villous
benign breast tumor
deficiency; hormone
neuromuscular blockade
systemic juvenile idiopathic arthritis
diabetic sensory polyneuropathy
hypercalcemia
cerebral meningioma
acute pancreatitis
major depressive episode
binucleate cell
fibroepithelial polyp
inflammation
biliary cirrhosis
embolism
idiopathic hirsutism
hyperthyroidism subclinical
hyperhomocysteinemia
cyst; follicular
nephrotoxic acute renal failure
chronic respiratory insufficiency
sick sinus syndrome
neural tube defect
soft tissue mass
prostate cancer
autonomic neuropathy
cartilage disease
cyst; renal
lipid disorder
glioblastoma
gh neurosecretory dysfunction
adjuvant arthritis
carpal tunnel syndrome
cushing syndrome
achondroplasia
bronchiolitis; obliterative
disease; heart
tumor compression
malnutrition; maternal
bladder cancer
lipid deposition
william syndrome
goiter nodular
demyelination
PWS
diseases; multiple
deficiency; iodine
increased growth
osteoarthritis
delayed puberty
laryngeal carcinoma
epidermal hyperplasia
muscle wasting (disuse)
nervous system abnormalities
telomere shortening
type a insulin resistance
coal worker pneumoconiosis
breast tumor
transient cerebral ischemia
leprechaunism
uremia
febrile neutropenia
decompensated cirrhosis
renal disease progressive
class i; histocompatibility complex
central sleep apnea
hnpcc
peripheral arterial disease
ocular melanoma
familial alzheimer disease
cardia
cavitation
chromosome fragility
acute tubular necrosis
weak; muscle
delayed ovulation
bacterial cystitis
infertility male
hyperparathyroidism primary
axis disorder
adrenal tumor
diabetic keratopathy
choledochal cyst
esophageal cancer
rett syndrome
cholera
genetic disorder
abuse; steroids
postoperative adhesion
duodenal ulcer
reflux; vesicoureteral
bovine leukemia
arthritis
hypothyroid
hallucination
high-grade squamous intraepithelial lesion
lung tumor
malignant pleural effusion
relapse
hypoplasia; pulmonary
ehs tumor
unexplained infertility
thymoma
gastrinoma
insufficiency; placental
cystic fibrosis
henoch-schonlein purpura
acidemia
retinal detachment traction
asphyxia
atherosclerosis
metaplasia
thyroid cold nodule
neuroblastoma
diabetes mellitus insulin-dependent
volume overload
failure heart
lymphoma
obesity hypoventilation syndrome
pancreatitis
anaphylactic reaction
childhood obesity
cognitive impairment
myopathies
diabetic complication
congenital heart defect
marasmus
cancer induction
twin-twin transfusion syndrome
left ventricular systolic dysfunction
metabolic syndrome
hemorrhagic necrosis
hypertension systolic
abdominal aortic coarctation
leukostasis
degenerative
necrosis
autistic
acidosis
peptic ulcer
abortion threatened
glioblastoma multiforme
thyroiditis
testis cancer
chondrosarcoma
fetal; tumor
myeloblastosis
infection; nematode
alveolar bone loss
hypoplasia; muscle
acute leukemia
non-alcoholic steatohepatitis
peritoneal mesothelioma
abuse; alcohol
epithelial tumor
disease; wilsons
hypotension, orthostatic
metastatic carcinoma
osteosarcoma
aortic coarctation
acute myocardial ischemia
prostate cancer stage
tumor initiation
hemangioblastoma
end stage liver disease
overfed
complication; treatment
facial dysmorphism
pituitary tumor
tissue adhesion
vitritis
acromegalic arthropathy
cystic endometrial hyperplasia
viral leukemia
ewing sarcoma
benign tumor
hypothalamo-pituitary disorder
occlusion; renal artery
dysfunction; renal tubular
torsions
acute ischemia
chronic gastric ulcer
delivery; prolonged
diaphragm; increased
uterine hypoplasia
interstitial fibrosis
peritonitis
peho syndrome
alcohol effect
papilloma
hepatocarcinogenesis
atypical hyperplasia
hypermobility syndrome
cystic disease
distortion
hemangiopericytoma
dawn phenomenon
severe toxemia
cholestatic liver disease
diabetes; unstable
stromal tumor
insulin sensitivity
extensive disease
autoimmune disease
zinc excess
hypogonadotrophic hypogonadism
detachment retinal
niemann-pick disease type b
ketonemia
arterial stenosis
acromegalic gigantism
emphysema
diabetes insipidus nephrogenic
carcinoma transitional cell
adult growth hormone deficiency
insufficiency renal
eschar
fetal acidosis
inactive acromegaly
intestinal ischemia
cholesterolemia
androgen deficiency
effusion
hemorrhage intracerebral
lethal midline granuloma
brachydactyly
skeletal neoplasm
nonobstructive hypertrophic cardiomyopathy
short stature
CHF
congenital myopathies
leukemia, t-cell
focal chronic inflammation
morbid obesities
hyperkeratosis
disc degeneration
focal necrosis
little disease
dysfunction; pituitary
eccentric hypertrophy
CLL
neuroendocrine tumor
breast cancer metastatic
mpnst
steatosis
insulin resistance syndrome, type b
mastitis
transgenic model
armanni-ebstein lesion
coronary occlusion
pituitary microadenoma
abnormal pregnancy
medulloblastoma
malignant solid tumor
hormone-refractory prostate cancer
idiopathic gh deficiency
acute myeloid leukemia
calcium deficiency
brain lesion
enteritis
primary fibromyalgia
uterine tumor
degeneration muscle
alcoholism
craniopharyngioma
disorder; metabolic
osteoporosis (osteopenia)
cleft palate
acanthosis nigricans
prolactin secreting pituitary tumor
schistosomiasis
ovary; polycystic (syndrome)
follicular carcinoma
juvenile idiopathic arthritis
anastomosis
polycythemia vera
neoplastic process
cerebellar atrophy
enzyme inhibition
insulin resistance
sodium retention
diabetic foot ulcer
aneurysm aortic
aids dementia complex
growth hormone; hypersecretion
microcephalies
preeclampsia, severe
muscle fiber atrophy
osteogenesis imperfecta
delay; developmental
syndrome withdrawal
hyperbilirubinemia
secondary adrenal insufficiency
late-onset cerebellar ataxia
fetal; hemoglobin
endometrial cancer
glucose tolerance impaired
intrahepatic cholangiocarcinoma
hypercortisolemia
disease; musculoskeletal
agenesis
luteal phase defect
mast cell hyperplasia
dysfunction; placental
dysplasia
tumor growth
glycogen storage disease type ib
anaplastic astrocytoma
premature ventricular contraction
salivary gland tumor
acne
edema
hypothyroidism primary
ureteral obstruction
disorder; relationship
gastrointestinal cancer
aortic regurgitation
cancer
abdominal obesity
insertion mutation
hypertension pulmonary
micropenis
hydrocephalus
embryonal carcinoma
cutaneous melanoma
growth arrest
meningitis
allergy; food
idiopathic precocious puberty
perthes disease
cell transformation
nephritic syndrome
media; otitis
osteonecrosis
testicular torsion
pnets
subfertility
noonan syndrome
neonatal hyperglycemia
effusion; joint
denticle
inflammatory cell infiltration
disorder sleep
brain tumor
climacteric syndrome
hypoparathyroidism
multiple endocrine neoplasia type 1
hypertrophy; ventricular
hypochondroplasia
dietary zinc deficiency
nerve paralysis
breast cancer, familial
papillary carcinoma
hernia inguinal
dysfunction; endocrine
ppoma
patella dysplasia
hemorrhagic stroke
testicular germ cell tumor
idiopathic short stature
epithelial hyperplasia
pygmy, african
muscle cachexia
airway disease
atherosclerotic plaque
ovarian hyperstimulation
pathological disorders
RA
ppnet
brca2 mutation
prostatic hypertrophy
pleurisies
fsgs
col2a1
catabolic state
werner syndrome
gigantism
ovarian failure premature
pregnancy prolonged
poor glycemic control
advanced cirrhosis
pancreatic cancer
hematologic malignancies
kidney; lesion
spondyloarthritis
perinatal asphyxia
cerebral ventricle
anatomical abnormality
spinocerebellar ataxia type 1
chronic renal failure
previous myocardial infarction
prosthesis loosening
pycnodysostosis
localized disease
mauriac syndrome
pleurisy; tuberculous
hypophosphatemia, x-linked
skeletal disorder
neuroaxonal dystrophies
disease graves
ischemic stroke
xenograft model
bullous keratopathy
autoimmune
spina bifida
hermansky-pudlak syndrome
stricture
cryptorchidism
neurological disease other
peripheral nerve lesion
osteomalacia
malignant pleural mesothelioma
concentric hypertrophy
inflammatory response
tumor angiogenesis
OA
adenomatous polyp
blast leukemia
blindness
multiple organ dysfunction syndrome
hyperinsulinemia
proliferative breast disease
retinoblastoma
essential hypertension
hyperadrenocorticism; pituitary-dependent
carcinoid syndrome
bone; change
hypoglycemia; insulin
dwarfism (pituitary)
ischemia
disorder; nutritional
hypomyelination
fetal macrosomia
schizophrenia
demineralization
pituitary infarction
mgus
advanced cancer
fracture; osteoporotic
tumor vasculature
SIDS
endogenous hyperinsulinism
renal scarring
arterial occlusion
adenocarcinoma gastric
herniated disc
alcoholic cirrhosis
deficiency; zinc
chronic hyperglycemia
gastrointestinal inflammation
idiopathic interstitial pneumonia
glomerulosclerosis
severe sepsis
glomerulopathy
adrenal hyperplasia congenital
hepatitis b
psychiatric disorder
effusion pleural
fibroepithelial tumor
hypofunction
scorbutic
congenital generalized lipodystrophies
malignant mesothelioma
pediatric osteosarcoma
adhd
impaired insulin secretion
neural deafness
stillborn
dwarf
disabilities, learning
alcohol; liver
endemic goiter
lesion; skin
adrenocortical tumor
drpla
catabolism increased
insulin tolerance
mammary adenocarcinoma
chronic uti
miscellaneous tumor
diabetes mellitus, overt
cardiac function impaired
gastric lesion
mental retardation; mild
acromegaly
sinus tachycardia
neurodegeneration
pressure ulcer
malnutrition; moderate
oropharyngeal tumor
adenoviral enteritis
diabetic hyperglycemia
ALS
hypothyroidism; subclinical
skeletal malformation
colonic polyp
diabetic autonomic neuropathies
retinopathies
heart; ischemic
hypersomatotropism
copd exacerbation
primary osteoporosis
skin cancer
diphtheria
blast cell proliferation
lipohypertrophy
hypersecretion; somatostatin
cardiac hypertrophy
carney complex
isolated gonadotropin deficiency
stroke
intimal proliferation
cancer differentiated poorly
cerebellar dysfunction
infection; intrauterine
hyperthyroid subclinical
human papillomavirus
hematological disorders
liver metastases
FCHL
chronic liver disease
hot spots
fanconi
ovarian adenocarcinoma
atrophy muscle
dystrophy (muscular)
bone metastases
hypogonadism
perinatal infections
pregnancy loss
pigmentosa; retinitis
disorder myeloproliferative
synovial sarcoma
myofibrosis
cancer relapse
k deficiency
multiple sclerosis, relapsing-remitting
hepatic insufficiency
malnutrition; severe
thyroid disease
bronchioloalveolar carcinoma
mucocele
aneuploid
multiple tumors
COPD
cardiac defect
premalignant lesion
drug-induced hepatitis
dysplasia; hip
gene fusion
disease; rheumatic heart
congenital heart disease
fetal damage
malignant disease
disease; liver
hypopituitarism
lesion; primary
brain infarction
diabetes mellitus malnutrition-related
hypertensive left ventricular hypertrophy
cirrhosis (liver)
hypophosphatemic ricket
malignant phyllodes tumor
diabetic ulcer
atresia biliary
large cell carcinoma
progressive pseudorheumatoid dysplasia
gastric fistula
endometrial tumor
insulinoma
psoriasis
neuroepithelioma
dysfunction ovarian
constitutional tall stature
hepatosplenic schistosomiasis
immunosuppression
autism spectrum disorder
cardiac; hypoplasia
colorectal cancer metastatic
fibrous dysplasia
aortic stenosis
escherichia coli; sepsis
hypophagia
decreased requirement
lymph node metastasis
hepatitis c
hyperandrogenism
chronic disease
idiopathic pulmonary fibrosis
disease; eye
genetic hypertension
hyperprolactinemia
malabsorption
middle cerebral artery occlusion
reflux nephropathy
eclampsia
gastrointestinal tumor
invasive prostate carcinoma
bacteremia
alkalosis
acute lymphoblastic leukemia
chronic hepatitis
bacterial infection, gram-negative
costello syndrome
breast disease fibrocystic
cecum tumor
hyperphagia
uveal melanoma
amenorrhea secondary
menstrual irregularities
cholangiocarcinoma
erythrocytosis
senile plaque
lymphoma (non-hodgkins)
diabetic glomerulosclerosis
secondary atrophy
multiple system atrophies
class ii; histocompatibility complex
type ii endometrial carcinoma
multiple myeloma
chronic lung disease
moyamoya disease
disease; peripheral vascular
pancreatic disease
high-risk cancer
FHA
atrophy; brain
chronic inflammation
gastrointestinal carcinoid tumor
immature lungs
rheumatic disease
hepatic granuloma
adult-onset growth hormone deficiency
heritable connective tissue disorder
hypertrophic scar
muscle damage
endometrium; postmenopausal
small-for-dates
community-acquired pneumonia
lung cancer
systemic disease
granulocytosis
role playing
disease; motor neuron
placental disease
myelodysplastic syndrome
osteoporosis senile
panniculitis
somatotroph hyperplasia
SCID
paget disease
pseudogout
hunter syndrome
vitamin b6 deficiencies
colon adenocarcinoma
parathyroid tumor
age-related bone loss
delayed-type hypersensitivity
infant sga
cartilage-hair hypoplasia
underwood
diabetic nephropathies
choroidal neovascularization
exogenous obesity
rectal cancer
hepatitis
oral cancer
euthyroid sick syndrome
motor deficit
sarcoidosis
tuberous sclerosis complex
duodenitis
neuropathy peripheral
vascular inflammations
claudication intermittent
aseptic loosening
diastolic dysfunction
thrombosis
blv infection
malignant smooth muscle tumor
biventricular failure
menopause surgical
precocious puberty
pancreatic enlargement
aromatase deficiency
cardiovascular disease
Nbs
colon tumor
congenital; cyanotic heart disease
withdrawal bleeding
iris neovascularization
preproliferative retinopathy
change; vascular
delirium
streptozotocin diabetes
chronic zinc deficiency
glaucoma
bone tumor
excavatum; pectus
hormone replacement
disease parkinsons
obese
blast crisis
tongue cancer
fibrosis pulmonary
ventricular dysfunction
syndrome; wasting
panhypopituitarism
interstitial lung disease
disorder, obsessive-compulsive
alveolar rhabdomyosarcoma
deficiency; immune
deficiency; growth hormone
hyperplastic polyp
disease; lung
hydrocephalus obstructive
cerebellar function
cyst; ovarian
chronic myeloid leukemia
solid tumor
schwannoma
hypoglycemic episode
intestinal cancer
somatotropinoma
cerebral ischemia
myositis
endometrial hyperplasia
plasmacytoma
caruncle
diabetes insipidus
goiter nontoxic
protein deposition
proliferative retinopathy
spot, white
anaplastic oligodendroglioma
fasting hypoglycemia
residual tumor
single gene defect
endometriosis
renal hypertrophy
dysmorphic features
fulminant wilsons disease
squamous papilloma
lung metastases
liver mass
medulloepithelioma
left ventricular dysfunction
adolescent idiopathic scoliosis
lymphangioleiomyomatosis
disease characteristic
multiple cysts
aneurysm
adenoma; pituitary
cardiac autonomic neuropathy
acne vulgaris
demyelinating disease
oncogenesis
intraepithelial prostatic neoplasia
brain pathology
atrophies
macroglossia
anaplastic ependymoma
disorder; eating
acute renal failure
enterocolitis necrotizing
fibrous histiocytoma malignant
endothelial dysfunction
peritoneal metastases
hypotensive
carcinoma papillary thyroid
cystadenoma mucinous
heart rate increased
edema generalized
densely granulated somatotroph adenoma
carcinogenicity
benign uterine tumor
gastrointestinal disease
adult soft tissue sarcoma
pancreatic exocrine cancer
angiosarcoma
withdrawal; drug
multiple cancer
skeletal muscle hypertrophy
benign prostate hyperplasia
hip osteopenia
cardiovascular complication
demyelinating neuropathy
ohss
b-all
iga nephropathies
squamous cell carcinoma
intestinal tumor
stump
psychological distress
hypertrophies
sinusitis
common variable immunodeficiencies
colorectal tumor
diabetes; renal
stasis
adenoma
infant vlbw
anemia, diamond-blackfan
pretibial myxedema
squamous metaplasia
GISTs
central hypothyroidism
narcosis
hypoplasia; limb
sporadic breast cancer
disease; serum
dysfunction thyroid
secondary erythrocytosis
liddle syndrome
tetraplegia
bone destruction
pituitary tumour benign
neurologic diseases
neck; web
malignant transformation
kaposi sarcoma
parasitemia
premenstrual syndrome
retrograde degeneration
ataxia; hereditary
persistent lymphocytosis
epilepticus; status
endotoxic shock
radiculopathies
robinow syndrome
facial deformity
PDA
ameloblastoma
hypoplasia; thyroid
death (sudden)
chronic uremia
fusion; spine
cancer cell growth
adrenal insufficiencies
adenocarcinoma
germ cell tumor
neuropathic ulcer
neck cancer
tumor; wilms
radiocontrast nephropathy
disorder; panic
hypophosphatemia
bronchopulmonary dysplasia
primary ciliary dyskinesia
congenital hyperinsulinism
dyslipidemia
primary empty sella syndrome
congenital hypothyroidism
SIRS
adrenal hyperplasia
cirrhosis; postnecrotic
poag
malnutrition, protein-energy
failure liver
simple obesity
mammary tumorigenesis
carcinoma hepatocellular
fat; heart
fibroadenoma
ankylosing spondylitis
men2b
dysplasia; epithelial
anorexia nervosa
mild; cognitive impairment
leukopenia
micrognathia
growth failure
paris-trousseau syndrome
cataract
disease complication
brain edema
anencephaly
cyst; liver
nuclear accumulation
goiter
thyroid cancer (follicular cell)
diabetic neuropathies
cholesterol depletion
sertoli cell tumor
granulomatous inflammation
dementia vascular
nephropathies
colonic dysplasia
myoma
adult disease
metastatic osteosarcoma
colon growth
retinal neovascularization
enteropathy
iron overload
vascular stenosis
synovitis
superficial bladder cancer
acromesomelic dysplasia, maroteaux type
multiple myeloma progression

Advanced Search (alpha)

IGF1 Gene

protein-coding GIFtS: 69

Aliases & Descriptionsfor IGF1 gene

Summariesfor IGF1 gene

Genomic Viewsfor IGF1 gene

Proteinsfor IGF1 gene

Protein Domains/Familiesfor IGF1 gene

Gene Functionfor IGF1 gene

Pathways & Interactionsfor IGF1 gene

Drugs & Compoundsfor IGF1 gene

Transcriptsfor IGF1 gene

Expression for IGF1 gene

Orthologsfor IGF1 gene

Paralogsfor IGF1 gene

Genomic Variantsfor IGF1 gene

Disorders & Mutationsfor IGF1 gene

Medical Newsfor IGF1 gene

Publicationsfor IGF1 gene

Search for IGF1 gene

Genome Databases showing IGF1 gene

Other Databases showing IGF1 gene

Specialized Databases showing IGF1 gene

Intellectual Propertyfor IGF1 gene

Servicesfor IGF1 gene

View Random Gene

Aliases &
Descriptions
for IGF1 gene

Summaries
for IGF1 gene

Genomic Views
for IGF1 gene

Proteins
for IGF1 gene

Protein Domains/
Families
for IGF1 gene

Gene Function
for IGF1 gene

Pathways & Interactions
for IGF1 gene

Drugs & Compounds
for IGF1 gene

Transcripts
for IGF1 gene

Expression
for IGF1 gene

Orthologs
for IGF1 gene

Paralogs
for IGF1 gene

Genomic Variants
for IGF1 gene

Disorders & Mutations
for IGF1 gene

Medical News
for IGF1 gene

Publications
for IGF1 gene

Intellectual Property
for IGF1 gene

Services
for IGF1 gene