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IFT74 Gene

protein-coding   GIFtS: 47
GCID: GC09P026947

Intraflagellar Transport 74 Homolog (Chlamydomonas)

(Previous name: coiled-coil domain containing 2)
(Previous symbol: CCDC2)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Intraflagellar Transport 74 Homolog (Chlamydomonas)1 2     Capillary Morphogenesis Gene 1 Protein2 3
CCDC21 2 3 5     Coiled-Coil Domain-Containing Protein 22 3
CMG12 3 5     CMG-12 3
Coiled-Coil Domain Containing 21 2     Intraflagellar Transport Protein 74 Homolog2
Capillary Morphogenesis Protein 11 2     

External Ids:    HGNC: 214241   Entrez Gene: 801732   Ensembl: ENSG000000968727   OMIM: 6080405   UniProtKB: Q96LB33   

Export aliases for IFT74 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IFT74 Gene:
IFT74 (intraflagellar transport 74 homolog (Chlamydomonas)) is a protein-coding gene. Diseases associated with IFT74 include frontotemporal dementia, and dementia. GO annotations related to this gene include chromatin binding.

UniProtKB/Swiss-Prot: IFT74_HUMAN, Q96LB3
Function: Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding
module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic
region. Required for ciliogenesis

Gene Wiki entry for IFT74 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NC_018920.2  NT_008413.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the IFT74 gene promoter:
         AP-2beta   AP-2gamma   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIFT74 promoter sequence
   Search Chromatin IP Primers for IFT74

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IFT74


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p21.2   Ensembl cytogenetic band:  9p21.2   HGNC cytogenetic band: 9p21.1

IFT74 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFT74 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P026947:  view genomic region     (about GC identifiers)

Start:
26,947,037 bp from pter      End:
27,062,931 bp from pter
Size:
115,895 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: IFT74_HUMAN, Q96LB3 (See protein sequence)
Recommended Name: Intraflagellar transport protein 74 homolog  
Size: 600 amino acids; 69239 Da
Subunit: Component of the IFT complex B, at least composed of IFT20, IFT25/HSPB11, IFT27, IFT52, IFT57, IFT74,
IFT81, IFT88 and TRAF3IP1. Interacts with IFT81; the interaction is direct: within the IFT complex B, IFT74 and
IFT81 mediate the transport of tubulin within the cilium. Interacts (via basic region) with beta-tubulin (via
acidic region); interaction is direct. Interacts with ARL13B
Sequence caution: Sequence=BAB14650.1; Type=Erroneous termination; Positions=159; Note=Translated as Lys;
Sequence=BAB15423.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q3B789 Q5VY34 Q6PGQ8 Q9H643 Q9H8G7
Alternative splicing: 2 isoforms:  Q96LB3-1   Q96LB3-2   

Explore the universe of human proteins at neXtProt for IFT74: NX_Q96LB3

Explore proteomics data for IFT74 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See IFT74 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001092692.1  NP_001092693.1  NP_001092694.1  NP_079379.2  

    ENSEMBL proteins: 
     ENSP00000430004   ENSP00000430096   ENSP00000369402   ENSP00000430526   ENSP00000393907  
     ENSP00000430742   ENSP00000389224   ENSP00000404122  

    IFT74 Human Recombinant Protein Products:

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    IFT74 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    IFT: Intraflagellar transport homologs

    ProtoNet protein and cluster: Q96LB3

    UniProtKB/Swiss-Prot: IFT74_HUMAN, Q96LB3
    Similarity: Belongs to the IFT74 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IFT74_HUMAN, Q96LB3
    Function: Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding
    module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic
    region. Required for ciliogenesis

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003682chromatin binding IEA--
    GO:0048487beta-tubulin binding IDA--
         
    IFT74 for ontologies           About GeneDecksing


    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ift74):
     cardiovascular system  growth/size/body  respiratory system 

    IFT74 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IFT74
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    miRNA
    Products:
        
    miRTarBase miRNAs that target IFT74:
    hsa-mir-103a-3p (MIRT027044), hsa-mir-16-5p (MIRT031787)

    Block miRNA regulation of human, mouse, rat IFT74 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate IFT74
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFT74


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IFT74_HUMAN, Q96LB3: Cell projection, cilium. Cytoplasmic vesicle. Note=Localizes along primary cilia at
    interphase and around the basal body/centriole at interphase and mitosis
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton4
    cytosol3
    mitochondrion3
    nucleus2

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm ----
    GO:0005813centrosome ----
    GO:0016023cytoplasmic membrane-bounded vesicle IEA--
    GO:0030992intraciliary transport particle B ISS--

    IFT74 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including IFT74: 
              Primary Cilia in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for IFT74

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for IFT74 (ENSP000003694024) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IFT27ENSP000003435934STRING: ENSP00000343593
    IFT52ENSP000003621214STRING: ENSP00000362121
    IFT81ENSP000002425914STRING: ENSP00000242591
    IFT88ENSP000003235804STRING: ENSP00000323580
    DYNC2LI1ENSP000002606054STRING: ENSP00000260605
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0033630positive regulation of cell adhesion mediated by integrin IEA--
    GO:0035735intraciliary transport involved in cilium morphogenesis IMP--
    GO:0042384cilium assembly IMP--
    GO:0045944positive regulation of transcription from RNA polymerase II promoter IEA--

    IFT74 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IFT74



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for IFT74 gene (4 alternative transcripts): 
    NM_001099222.1  NM_001099223.1  NM_001099224.1  NM_025103.2  

    Unigene Cluster for IFT74:

    Intraflagellar transport 74 homolog (Chlamydomonas)
    Hs.145402  [show with all ESTs]
    Unigene Representative Sequence: NM_001099222
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000519968 ENST00000517444 ENST00000380062(uc003zqg.4) ENST00000518614
    ENST00000429045(uc003zqf.4) ENST00000517866 ENST00000494236 ENST00000482986
    ENST00000433700(uc010mja.3) ENST00000443698(uc010mjb.3)
    miRNA
    Products:
         
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat IFT74
      QuantiFast Probe-based Assays in human, mouse, rat IFT74

    Additional mRNA sequence: 

    AK023707.1 AK026274.1 AK225570.1 AY040325.1 BC023634.2 BC056875.1 BC107742.1 BC113524.1 
    BC113526.1 

    11 DOTS entries:

    DT.95369755  DT.40209770  DT.213564  DT.121169020  DT.99999977  DT.100024408  DT.101969749  DT.121169029 
    DT.121169056  DT.91731942  DT.95283063 

    Selected AceView cDNA sequences (see all 107):

    BC056875 BM975339 AI370731 BG287033 CA425929 AA864905 CD677826 CR617782 
    CA397990 AI630740 AY040325 CR621331 CA397989 BG540890 W95531 AA029010 
    W95494 AA975848 BC023634 AI919195 AA804783 CF128892 BU679106 AI040076 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IFT74 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATTTAGAGG
    IFT74 Expression
    About this image

    IFT74 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IFT74 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.145402

    UniProtKB/Swiss-Prot: IFT74_HUMAN, Q96LB3
    Tissue specificity: Highly expressed in adult and fetal kidney and expressed at lower level in adult heart,
    placenta, lung, liver and pancreas, and in fetal heart, lung and liver. Little to no expression was detected in
    adult brain and skeletal muscle or in fetal brain, thymus and spleen

        Pathway & Disease-focused RT2 Profiler PCR Array including IFT74: 
              Primary Cilia in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFT74

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for IFT74 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ift741 , 5 intraflagellar transport 74 homolog (Chlamydomonas)5
    intraflagellar transport 741
    88.18(n)1
    88.13(a)1
      4 (43.34 cM)5
    676941  NM_026319.21  NP_080595.21 
     946144915 
    chicken
    (Gallus gallus)
    Aves IFT741 intraflagellar transport 74 homolog (Chlamydomonas) 73.01(n)
    66.72(a)
      427367  XM_003643070.2  XP_003643118.1 
    lizard
    (Anolis carolinensis)
    Reptilia IFT746
    intraflagellar transport 74 homolog (Chlamydomonas...
    73(a)
    1 ↔ 1
    2(58948408-58972805)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia ift741 intraflagellar transport 74 homolog 70.69(n)
    69.51(a)
      548816  NM_001016062.2  NP_001016062.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:920521 zgc:92052 61.1(n)
    60.24(a)
      436658  NM_001002385.1  NP_001002385.2 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0047241 AgaP_AGAP004724 44.89(n)
    31.93(a)
      1278504  XM_318104.4  XP_318104.4 
    worm
    (Caenorhabditis elegans)
    Secernentea ift-741 ift-74 47.12(n)
    30.36(a)
      174102  NM_062958.3  NP_495359.1 


    ENSEMBL Gene Tree for IFT74 (if available)
    TreeFam Gene Tree for IFT74 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IFT74 gene
    6 SIMAP similar genes for IFT74 using alignment to 7 protein entries:     IFT74_HUMAN (see all proteins):
    FAM3A    CNOT2    NSD1    C12orf23    ZNF738    UTY

    IFT74 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IFT74 (see all 2055)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1431954151,2
    --26949570(+) TTCCCA/TGTGTA 2 -- int10--------
    rs1482600141,2
    --26949581(+) ATTGCC/TTGCTG 2 -- int10--------
    rs1412624941,2
    C--26949597(+) CAAAAA/CACCAA 2 -- int10--------
    rs1474150881,2
    --26949637(+) GGAAAC/GATGAA 2 -- int10--------
    rs122378671,2
    C,F--26949686(+) ttctcA/Gaatcc 2 -- int12Minor allele frequency- G:0.40WA EA 238
    rs1895257301,2
    C--26949762(+) GAAATA/GCTAAT 2 -- int10--------
    rs625466851,2
    C,F--26949822(+) CCTGAG/CTCATT 2 -- int14Minor allele frequency- C:0.08WA NA 242
    rs1812299521,2
    --26949947(+) TAGGAG/TTACTT 2 -- int10--------
    rs1866980081,2
    --26949953(+) TACTTA/GGCGAA 2 -- int10--------
    rs1899386671,2
    --26949962(+) AAGTTA/TCAAAT 2 -- int10--------

    HapMap Linkage Disequilibrium report for IFT74 (26947037 - 27062931 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for IFT74:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2677119CNV Deletion23128226
    nsv466334CNV Loss19166990
    nsv528614CNV Gain19592680
    nsv517269CNV Gain19592680
    nsv892862CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IFT74
    DNA2.0 Custom Variant and Variant Library Synthesis for IFT74

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608040    OMIM disorders: --

    5 diseases for IFT74:    About MalaCards
    frontotemporal dementia    dementia    lateral sclerosis    amyotrophic lateral sclerosis
    malaria

    1 disease from the University of Copenhagen DISEASES database for IFT74:
    Frontotemporal dementia

    IFT74 for disorders           About GeneDecksing

    Genetic Association Database (GAD): IFT74

    Export disorders for IFT74 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IFT74 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with IFT74)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling. (PubMed id 11683410)1, 2, 3 Bell S.E.... Davis G.E. (J. Cell Sci. 2001)
    2. Molecular basis of tubulin transport within the cilium by IFT74 and IFT81. (PubMed id 23990561)1, 2 Bhogaraju S....Lorentzen E. (Science 2013)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomain. (PubMed id 24339792)2 Cevik S....Blacque O.E. (PLoS Genet. 2013)
    6. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (J. Cell. Sci. 2012)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    10. Genetic studies of GRN and IFT74 in amyotrophic lateral sclerosis. (PubMed id 17383054)1 Xiao S....Rogaeva E. (Neurobiol. Aging 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 80173 HGNC: 21424 AceView: CCDC2 Ensembl:ENSG00000096872 euGenes: HUgn80173
    ECgene: IFT74 H-InvDB: IFT74

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IFT74 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IFT74 gene:
    Search GeneIP for patents involving IFT74

    GeneCards and IP:
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