IFT122 Gene
protein-coding GIFtS: 49
GCID: GC03P129158
|
|
intraflagellar transport 122 homolog (Chlamydomonas)(Previous name: WD repeat domain 10 )
(Previous symbol: WDR10)
| |
Aliases
for IFT122 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Intraflagellar Transport 122 Homolog (Chlamydomonas)1 2 | | WD Repeat-Containing Protein 102 3 | | WDR101 2 3 5 | | WD Repeat-Containing Protein 1402 3 | | SPG1 2 3 | | CED2 5 | | WDR1401 2 3 | | CED12 | | WDR10p1 2 | | Intraflagellar Transport Protein 122 Homolog2 | | WD Repeat Domain 101 2 | | |
Export aliases for IFT122 gene to outside databasesPrevious GC identifers: GC03P130642 GC03P126542 |
Summaries
for IFT122 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for IFT122:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric ormultiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycleprogression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeatsand an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternatetranscriptional splice variants, encoding different isoforms, have been characterized. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: IF122_HUMAN, Q9HBG6Function: Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling.Required to recruit TULP3 to primary cilia (By similarity)
|
Genomic Views
for IFT122 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the IFT122 gene promoter:
FOXF2 Pbx1a AML1a AP-4 Nkx2-5 CREB Pax-3 deltaCREB RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for IFT122
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IFT122 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q21 Ensembl cytogenetic band: 3q21.3 HGNC cytogenetic band: 3q21IFT122 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P129158: view genomic region
(about GC identifiers)
Start:
|
129,158,968 bp from pter |
End:
|
129,239,198 bp from pter |
Size:
|
80,231 bases |
Orientation:
|
plus strand |
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Proteins
for IFT122 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: IF122_HUMAN, Q9HBG6 (See
protein sequence)Recommended Name: Intraflagellar transport protein 122 homolog Size: 1241 amino acids; 141825 Da
Subunit: Component of the IFT complex A (IFT-A) complex
Subcellular location: Cytoplasm. Cell projection, cilium (By similarity). Cytoplasm, cytoskeleton, cilium basal body(By similarity). Note=Localizes to photoreceptor connecting cilia (By similarity)
Secondary accessions: G3XAB1 Q53G36 Q9BTB9 Q9BTY4 Q9HAT9 Q9HBG5 Q9UF80Alternative splicing: 5 isoforms: Q9HBG6-1 Q9HBG6-2 Q9HBG6-3 Q9HBG6-4 Q9HBG6-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for IFT122: NX_Q9HBG6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HBG6
IFT122 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_060732.2 NP_443711.2 NP_443715.1 NP_443716.1
ENSEMBL proteins: ENSP00000323973 ENSP00000296266 ENSP00000425536 ENSP00000421953 ENSP00000422179 ENSP00000324165 ENSP00000324005 ENSP00000423902 ENSP00000427061 ENSP00000427027 ENSP00000423921 ENSP00000421140 ENSP00000425540 ENSP00000424206 ENSP00000423288 ENSP00000422237 ENSP00000424727 ENSP00000427515 ENSP00000410946 ENSP00000401569
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
IFT122 for ontologies About GeneDecksing
IFT122 Antibody Products:
Assay Products for IFT122: |
Protein
Domains /
Families
for IFT122 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
IFT122 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9HBG6ProtoNet protein and cluster: Q9HBG6 UniProtKB/Swiss-Prot: IF122_HUMAN, Q9HBG6Similarity: Contains 7 WD repeats |
Function
for IFT122 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: IF122_HUMAN, Q9HBG6Function: Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling.Required to recruit TULP3 to primary cilia (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IFT122 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IFT122 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): IFT122 (NM_052989) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IFT122 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFT122 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFT122 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- |
IFT122 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for IFT122:
Animal Models:
Mouse knock-out Mbd4/Ift122Mbd4/tm1Abc for IFT122
12 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Ift122):
IFT122 for phenotypes About GeneDecksing
|
Pathways & Interactions
for IFT122 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IFT122
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for IFT122 (Q9HBG61 ENSP000002962664) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001843 | neural tube closure |
ISS | -- | | GO:0009953 | dorsal/ventral pattern formation |
-- | -- | | GO:0010172 | embryonic body morphogenesis |
ISS | -- | | GO:0035050 | embryonic heart tube development |
ISS | -- | | GO:0042733 | embryonic digit morphogenesis |
-- | -- |
IFT122 for ontologies About GeneDecksing
|
Drugs & Compounds
for IFT122 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for IFT122
Search CenterWatch for drugs/clinical trials and news about IFT122 / IF122
|
Transcripts
for IFT122 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for IFT122 gene (4 alternative transcripts): NM_018262.2 NM_052985.2 NM_052989.1 NM_052990.1 Unigene Cluster for IFT122: Intraflagellar transport 122 homolog (Chlamydomonas) Hs.655284 [show with all ESTs]Unigene Representative Sequence: NM_05298518/32 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 32): ENST00000347300(uc011bkx.1 uc003emn.3 uc003emo.3 uc011bky.2)
ENST00000296266(uc003eml.3 uc003emm.3 uc010htc.3) ENST00000507564
ENST00000512220 ENST00000504021(uc011bkz.1 uc011bla.2 uc003emr.3 uc003ems.3)
ENST00000349441 ENST00000348417 ENST00000506507 ENST00000504653 ENST00000510524
ENST00000502456 ENST00000502304 ENST00000514275 ENST00000508826 ENST00000509195
ENST00000509815 ENST00000512157 ENST00000515783
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IFT122 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IFT122 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): IFT122 (NM_052989) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for IFT122 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFT122 |
Additional cDNA sequence: AF244930.1 AF244931.1 AF302154.1 AK001759.1 AK001955.1 AK022525.1 AK023000.1 AK094922.1 AK096891.1 AK122965.1 AK124140.1 AK124746.1 AK223095.1 AK293852.1 AK294515.1 AK298526.1 AK299903.1 AK307463.1 AK315103.1 AL133565.1 AL833851.1 BC003045.1 BC004238.2 BC028353.2 24/29 DOTS entries (see all 29): DT.101975207 DT.100779262 DT.97859078 DT.120893181 DT.100795821 DT.95278315 DT.120893262 DT.97859077 DT.120893288 DT.97859075 DT.92035781 DT.40269058 DT.100795818 DT.97768451 DT.91745898 DT.120893211 DT.92035783 DT.100673076 DT.106993 DT.91847028 DT.100795817 DT.120893166 DT.120893199 DT.120893217 24/202 AceView cDNA sequences (see all 202): BF724649 BM677165 BM466117 NM_052990 AK001955 NM_052989 NM_052985 CA489076 BM746796 AK122965 BX353635 CD674266 BM698872 AI682291 BM699960 BC004238 BQ548778 AL833851 AK093440 AK096891 AK024435 AL041642 BF513844 AI225089
GeneLoc Exon Structure
5/19 Alternative Splicing Database (ASD) splice patterns (SP) for IFT122 (see all 19) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | · | 1g | · | 1h | · | 1i | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | - | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | - | | | | - | | | | | | | | | | | | | | | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | - | | | | - | | | | | | | | | | - | | | | | | - | | |
| SP5: | | | | | | | | | | | | | | | | | | | - | | | | | | | | - | | | | - | | | | - | | | | | | | | - | | - | | - | | | | - | |
| ExUns: | 13b | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | · | 20c | ^ | 21 | ^ | 22a | · | 22b | · | 22c | ^ | 23a | · | 23b | · | 23c | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28a | · | 28b | ^ | 29 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 30 | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 |
|---|
|
| SP1: | | | | | | | | | | | |
| SP2: | | | | | | | | | | | |
| SP3: | | | | | | | | | | | |
| SP4: | | | | | | | | | | | |
| SP5: | | | | | | | | | | |
ECgene alternative splicing isoforms for IFT122
|
Expression
for IFT122 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| IFT122 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACCAGCATCC
About this image
See IFT122 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for IFT122
SOURCE GeneReport for Unigene cluster: Hs.655284
UniProtKB/Swiss-Prot: IF122_HUMAN, Q9HBG6Tissue specificity: Expressed in many tissues. Predominant expression in testis and pituitary
SABiosciences Custom PCR Arrays for IFT122
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IFT122
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IFT122 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IFT122 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IFT122 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFT122 |
Orthologs
for IFT122 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for IFT122 gene from 6/24 species (see all 24) About this table
ENSEMBL Gene Tree for IFT122 (if available)
TreeFam Gene Tree for IFT122 (if available) |
Paralogs
for IFT122 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for IFT122 gene
18/49 SIMAP similar genes for IFT122 using alignment to 19 protein entries: IF122_HUMAN (see all proteins)
(see all similar genes):COX7A2 MTA3 NUSAP1 ZNF568 DKFZp434O139 CCPG1
KLHDC1 NSRP1 THADA DKFZp434K016 FAM3A IPO7
NSD1 ZNHIT3 FLJ00025 SCLT1 C12orf23 DAPK2
IFT122 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for IFT122
PGOHUM00000250254 PGOHUM00000259868
|
Genomic Variants
for IFT122 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for IFT122 (129158968 - 129239198 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for IFT122
1 CNV: 68461
Human Gene Mutation Database (HGMD): IFT122
Locus Specific Mutation Databases (LSDB): IFT122
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IFT122 |
|
Disorders
/ Diseases
for IFT122 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
IFT122 for disorders About GeneDecksing
OMIM gene information: 606045
OMIM disorders: 218330
UniProtKB/Swiss-Prot: IF122_HUMAN, Q9HBG6
Defects in IFT122 are a cause of cranioectodermal dysplasia type 1 (CED1) [MIM:218330]. CED1 is a disordercharacterized by craniofacial, skeletal and ectodermal abnormalities. Clinical features include dolichocephaly (withor without sagittal suture synostosis), scaphocephaly, short stature, limb shortening, short ribs, narrow chest,brachydactyly, renal failure and hepatic fibrosis, small and abnormally shaped teeth, sparse hair, skin laxity andabnormal nails
15  diseases for IFT122: About MalaCardspelizaeus-merzbacher disease japanese spotted fever endemic typhus trigeminal neuralgia
vasomotor rhinitis spotted fever short stature sensenbrenner syndrome
vestibular neuronitis synostosis brachydactyly paraplegia
rhinitis neuronitis hepatitis
4 diseases from the University of Copenhagen DISEASES database for IFT122:Paraplegia Afferent loop syndrome Sensenbrenner syndrome Pelizaeus-Merzbacher disease Export disorders for IFT122 gene to outside databases
|
Publications
for IFT122 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for IFT122 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with IFT122) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and characterization of human WDR10, a novel gene located at 3q21 encoding a WD-repeat protein that is highly expressed in pituitary and testis. (PubMed id 11242542)1, 2, 3, 9 Gross C.... Messiaen L. (2001)
- Cranioectodermal Dysplasia, Sensenbrenner syndrome, i s a ciliopathy caused by mutations in the IFT122 gene. (PubMed id 20493458)1, 2 Walczak-Sztulpa J....Kuss A.W. (2010)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. (PubMed id 20889716)2 Mukhopadhyay S....Jackson P.K. (2010)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- A germline-specific class of small RNAs binds mammali an Piwi proteins. (PubMed id 16751776)1 Girard A....Carmell M.A. (2006)
- The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (2006)
|
External Searches for IFT122 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing IFT122 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing IFT122 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing IFT122 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for IFT122 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for IFT122 gene:
Search GeneIP for patents involving IFT122
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for IFT122 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for IFT122 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IFT122 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for IFT122 | | | OriGene Protein Over-expression Lysate for IFT122 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for IFT122 | | OriGene 3'-UTR Clone for IFT122 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IFT122 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IFT122 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for IFT122 | | OriGene Custom Protein Services for IFT122 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat IFT122 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IFT122 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IFT122 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IFT122 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IFT122 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IFT122 |
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| | | | Search Tocris compounds for IFT122 |
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 | | | IFT122 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFT122 |
|  |  |  | | | | Search ThermoFisher Antibodies for IFT122 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFT122 |
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