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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IFRD2 Gene

protein-coding   GIFtS: 50
GCID: GC03M050325

interferon-related developmental regulator 2
 Explore 3 diseases affiliated with
IFRD2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for IFRD2    

Aliases
for IFRD2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Interferon-Related Developmental Regulator 21 2
IFNRP1 2
SKMc151 2
SM151 2
Interferon-Related Protein2
Protein SKMC153

External Ids:    HGNC: 54571   Entrez Gene: 78662   Ensembl: ENSG000002147067   OMIM: 6027255   UniProtKB: Q128943   

Export aliases for IFRD2 gene to outside databases

Previous GC identifers: GC03P049650 GC03P049820 GC03M050180 GC03M050285 GC03M050278 GC03M050302 GC03M050303


Summaries
for IFRD2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
  --

Genomic Views
for IFRD2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IFRD2 gene promoter:
         ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): IFRD2 promoter sequence
   Search SABiosciences Chromatin IP Primers for IFRD2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IFRD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.3   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.3

IFRD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFRD2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M050325:  view genomic region     (about GC identifiers)

Start:
 50,325,163 bp from pter      End:
 50,330,349 bp from pter
Size:
 5,187 bases      Orientation:
 minus strand

Proteins
for IFRD2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: IFRD2_HUMAN, Q12894 (See protein sequence)
Recommended Name: Interferon-related developmental regulator 2  
Size: 506 amino acids; 54814 Da
Caution: It is uncertain whether Met-1 or Met-65 is the initiator
Sequence caution: Sequence=AAH01327.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAH01676.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAH07265.1;
Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAH07437.3; Type=Erroneous initiation;
Note=Translation N-terminally extended;
Secondary accessions: Q9BVB4

Explore the universe of human proteins at neXtProt for IFRD2: NX_Q12894

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q12894

    • IFRD2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006755.4  
    ENSEMBL proteins: 
     ENSP00000402849   ENSP00000408549   ENSP00000392316   ENSP00000415448   ENSP00000413726  
     ENSP00000336936   ENSP00000398971  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: IFRD2
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    Novus Biologicals IFRD2 Protein
    Novus Biologicals IFRD2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for IFRD2

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--


    IFRD2 for ontologies           About GeneDecksing



    IFRD2 Antibody Products: 
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    Novus Biologicals IFRD2 Antibodies
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    Uscn Antibodies for IFRD2
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    Uscn ELISAs and CLIAs for IFRD2

    Protein Domains /
    Families
    for IFRD2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IFRD2 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR011989 ARM-like
     IPR007701 Interferon-rel_develop_reg_N
     IPR006921 Interferon-rel_develop_reg_C
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q12894

    ProtoNet protein and cluster: Q12894

    1 Blocks protein family: IPB006921 Interferon-related protein conserved region

    UniProtKB/Swiss-Prot: IFRD2_HUMAN, Q12894
    Similarity: Belongs to the IFRD family


    Function
    for IFRD2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:
         Genatlas biochemistry entry for IFRD2:
    interferon-related developmental regulator 2,transcript from a region commonly deleted in small cell lung cancer
    lines,expressed in the initial stages of embryogenesis,in fetal and adult tissues,(predominantly in skeletal and
    cardiac muscle),rodent immediate early response gene homolog (murine PC4,rat TIS7), IFRD1 family

    miRNA
    Products:            		miRTarBase miRNAs that target IFRD2:
    hsa-mir-124 (MIRT002649), hsa-mir-16 (MIRT001452)

    OriGene 3'-UTR Clone: IFRD2
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IFRD2
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate IFRD2:
    hsa-miR-4324 hsa-miR-659 hsa-miR-4251 hsa-miR-3065-3p hsa-miR-3182 hsa-miR-34a*
    SwitchGear 3'UTR luciferase reporter plasmid: IFRD2 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IFRD2 (see all 7)
    OriGene shRNA RFP: IFRD2
    OriGene siRNA: IFRD2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IFRD2

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for IFRD2

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IFRD2 (see all 4)
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: IFRD2 (NM_006764)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFRD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFRD2 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for IFRD2
    Search LifeMap BioReagents cell lines for IFRD2

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFRD2

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding IPI--


    IFRD2 for ontologies           About GeneDecksing



    Pathways & Interactions
    for IFRD2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IFRD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    5/19 Interacting proteins for IFRD2 (Q128941, 3 ENSP000003989714) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    OAS3Q9Y6K51, 3, ENSP000002289284EBI-6115935,EBI-6115729 I2D: score=1 STRING: ENSP00000228928
    G3BP1Q132833, ENSP000003485784I2D: score=1 STRING: ENSP00000348578
    USP36Q9P2753, ENSP000003105904I2D: score=1 STRING: ENSP00000310590
    ADPRHENSP000003494964STRING: ENSP00000349496
    CREMENSP000002653724STRING: ENSP00000265372
    About this table

    Drugs & Compounds
    for IFRD2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IFRD2
    Search CenterWatch for drugs/clinical trials and news about IFRD2 

    Transcripts
    for IFRD2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for IFRD2 gene: 
    NM_006764.4  

    Unigene Cluster for IFRD2:

    Interferon-related developmental regulator 2
    Hs.743323  [show with all ESTs]
    Unigene Representative Sequence: Y12395
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000417626(uc011bdp.2) ENST00000426499 ENST00000436390(uc003czb.3)
    ENST00000474556 ENST00000464258 ENST00000486322 ENST00000438296 ENST00000492387
    ENST00000469855 ENST00000414734 ENST00000483071 ENST00000489569 ENST00000484043
    ENST00000462001 ENST00000468737 ENST00000336089 ENST00000429673

    miRNA
    Products:             		 OriGene 3'-UTR Clone: IFRD2
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IFRD2
    6 QIAGEN miScript miRNA Assays for microRNAs that regulate IFRD2:
    hsa-miR-4324 hsa-miR-659 hsa-miR-4251 hsa-miR-3065-3p hsa-miR-3182 hsa-miR-34a*
    SwitchGear 3'UTR luciferase reporter plasmid: IFRD2 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IFRD2 (see all 7)
    OriGene shRNA RFP: IFRD2
    OriGene siRNA: IFRD2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IFRD2
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IFRD2 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IFRD2 (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: IFRD2 (NM_006764)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFRD2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFRD2 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IFRD2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IFRD2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IFRD2

    Additional cDNA sequence: 

    AK074763.1 AK097765.1 AK309114.1 BC001327.1 BC001676.2 BC007265.1 BC007437.2 BT019999.1 
    U09585.1 Y12395.1 

    20 DOTS entries:

    DT.454516  DT.100815135  DT.100815140  DT.101959858  DT.92444818  DT.100815138  DT.95205403  DT.120846696 
    DT.100815133  DT.95195756  DT.120846804  DT.75126630  DT.100708651  DT.120846806  DT.416076  DT.86844180 
    DT.95195692  DT.95195753  DT.120846738  DT.95194368 

    24/510 AceView cDNA sequences (see all 510):

    CR614993 BU951922 BM976273 AI290004 BU952179 BC004483 NM_006764 CB528453 
    AA857646 AI003352 CF146834 AF040710 BM793195 BG258392 CR594453 BM989194 
    AF040706 AF502910 CR608020 AA594445 BU160519 BE904712 AA579404 AW410513 

    GeneLoc Exon Structure


    Expression
    for IFRD2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IFRD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGGTGGGTAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    IFRD2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    CartilageLumbar Intervertebral DiscIntervertebral Disc Nucleus Pulposus CellsCartilage
    Primitive StreakNotochordPrimitive Streak
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See IFRD2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IFRD2

    SOURCE GeneReport for Unigene cluster: Hs.743323

    UniProtKB/Swiss-Prot: IFRD2_HUMAN, Q12894
    Tissue specificity: Expressed in a variety of tissues

        SABiosciences Expression via Pathway-Focused PCR Array including IFRD2: 
              Interferons & Receptors in human mouse rat

    Primer
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    In Situ
    Assay Products:     
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    Orthologs
    for IFRD2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for IFRD2 gene from 8/23 species (see all 23)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Ifrd21 , 5 interferon-related developmental regulator 21, 5 85.34(n)1
    88.44(a)1    		   9 (58.24 cM)5
    159831  NM_025903.21  NP_080179.11 
     1075877185 
    lizard
    (Anolis carolinensis)    		 Reptilia IFRD26
    		 --
    		 65(a)
    		 1 ↔ 1
    		 2(149835081-149848202)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.199392 Transcribed sequence with weak similarity to protein more 72.14(n)    AL856635.2 
    zebrafish
    (Danio rerio)    		 Actinopterygii ifrd21 interferon-related developmental regulator 2 58.91(n)
    57.83(a)    		   445227  NM_001003621.1  NP_001003621.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG316946
    		 --
    		 36(a)
    		 1 → many
    		 2L(2868627-2874518)
    worm
    (Caenorhabditis elegans)    		 Secernentea F58B3.66
    		 Protein F58B3.6
    		 25(a)
    		 1 → many
    		 IV(11636623-11638186)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons SAT321 Interferon-related developmental regulator domain-containing more 39.83(n)
    30.13(a)    		   839669  NM_202194.2  NP_973923.1 
    rice
    (Oryza sativa)    		 Liliopsida Os03g04487001 hypothetical protein 39.1(n)
    31.08(a)    		   4333231  NM_001057007.1  NP_001050472.1 


    ENSEMBL Gene Tree for IFRD2 (if available)
    TreeFam Gene Tree for IFRD2 (if available) 

    Paralogs
    for IFRD2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IFRD2 gene
    IFRD12  
    1 SIMAP similar gene for IFRD2 using alignment to 5 protein entries:     IFRD2_HUMAN (see all proteins):
    IFRD1

    IFRD2 for paralogs           About GeneDecksing



    Genomic Variants
    for IFRD2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/134 NCBI SNPs in IFRD2 are shown (see all 134)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs126295721,2
    		C,F,H,--50324672(+) GTTGGT/GGGGGG 1 -- int118Minor allele frequency- G:0.26NS EA WA CSA NA EU 3555
    rs1931439241,2
    		--50324711(+) TTCCCC/TACTGC 2 -- int1 ut310--------
    rs1857360071,2
    		--50324845(+) GCCTCA/GCTTTG 2 -- ut31 int10--------
    rs1902096961,2
    		--50324891(+) CTGGCG/TCCTCC 2 -- ut31 int10--------
    rs1388575011,2
    		C,--50324967(+) CATAG-/CAAT  
                CAATC     		2 -- int1 ut310--------
    rs32167821,2
    		C,--50325019(-) TCTTT-/TTAAGAG 2 -- int1 ut310--------
    rs2003860501,2
    		--50325516(+) TCATT-/AAAAAA 2 -- ut310--------
    rs1816714151,2
    		--50325548(+) GGAGAA/CCAGTT 2 -- int1 ut310--------
    rs1859597901,2
    		C,--50325579(+) AAATAC/TGGACC 2 -- ut31 int10--------
    rs22296481,2
    		C,F,H,--50325638(-) CAAGCG/AGGCAG 3 /Q /R int1 mis18Minor allele frequency- A:0.05MN NS EA NA WA 540

    HapMap Linkage Disequilibrium report for IFRD2 (50325163 - 50330349 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for IFRD2
         4 CNVs: 30176 4335 3429 4336

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IFRD2
    DNA2.0 Custom Variant and Variant Library Synthesis for IFRD2

    Disorders / Diseases
    for IFRD2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    IFRD2 for disorders           About GeneDecksing

    OMIM gene information: 602725    OMIM disorders: --

    3 diseases for IFRD2:    About MalaCards
    alopecia areata    alopecia    lung cancer

    1 disease from the University of Copenhagen DISEASES database for IFRD2:
    Alopecia areata
    Human Genome Epidemiology (HuGE) Navigator: IFRD2 (1 document)

    Export disorders for IFRD2 gene to outside databases

    Publications
    for IFRD2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IFRD2 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with IFRD2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The human homolog of the rodent immediate early response genes, PC4 and TIS7, resides in the lung cancer tumor suppressor gene region on chromosome 3p21. (PubMed id 9050919)1, 2, 3 Latif F.... Lerman M.I. (1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
    4. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    5. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    6. Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
    7. Genetic variation and antioxidant response gene expre ssion in the bronchial airway epithelium of smokers at risk for lung cancer. (PubMed id 20689807)1 Wang X....Bell D.A. (2010)
    8. Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PubMed id 19953087)1 Persaud A....Rotin D. (2009)
    9. Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)
    10. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (2006)

    External Searches for IFRD2 gene

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    Genome Databases showing IFRD2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7866 HGNC: 5457 AceView: HYAL3 Ensembl:ENSG00000214706 euGenes: HUgn7866
    ECgene: IFRD2 H-InvDB: IFRD2

    Other Databases showing IFRD2 gene

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    Specialized Databases showing IFRD2 gene

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    NameDescription
    PharmGKB entry for IFRD2 Pharmacogenomics, SNPs, Pathways

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    		Patent Information for IFRD2 gene:
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