Aliases for IFRD1 Gene
External Ids for IFRD1 Gene
This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
GeneCards Summary for IFRD1 Gene
IFRD1 (Interferon-Related Developmental Regulator 1) is a Protein Coding gene. Diseases associated with IFRD1 include spinocerebellar ataxia 18 and cystic fibrosis. Among its related pathways are Hypertrophy Model.
UniProtKB/Swiss-Prot for IFRD1 Gene
Could play a role in regulating gene activity in the proliferative and/or differentiative pathways induced by NGF. May be an autocrine factor that attenuates or amplifies the initial ligand-induced signal (By similarity).