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IFNW1 Gene

protein-coding   GIFtS: 56
GCID: GC09M021103

Interferon, Omega 1

  See IFNW1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Interferon, Omega 11 2
Interferon Omega-11 2
Interferon Alpha-II-12 3
IFN-Omega 11
IFN-Omega 1, Interferon Omega-12

External Ids:    HGNC: 54481   Entrez Gene: 34672   Ensembl: ENSG000001770477   OMIM: 1475535   UniProtKB: P050003   

Export aliases for IFNW1 gene to outside databases

Previous GC identifers: GC09M021468 GC09M021341 GC09M021130


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IFNW1 Gene:
IFNW1 (interferon, omega 1) is a protein-coding gene. Diseases associated with IFNW1 include dengue hemorrhagic fever, and cutaneous malignant melanoma. GO annotations related to this gene include cytokine receptor binding and cytokine activity. An important paralog of this gene is IFNA7.

Gene Wiki entry for IFNW1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NC_018920.2  NT_008413.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the IFNW1 gene promoter:
         SRF   COUP-TF1   SRF (504 AA)   COUP   CUTL1   HNF-4alpha2   HNF-4alpha1   HEN1   S8   COUP-TF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIFNW1 promoter sequence
   Search Chromatin IP Primers for IFNW1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IFNW1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p22   Ensembl cytogenetic band:  9p21.3   HGNC cytogenetic band: 9p22

IFNW1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFNW1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M021103:  view genomic region     (about GC identifiers)

Start:
21,140,631 bp from pter      End:
21,142,144 bp from pter
Size:
1,514 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: IFNW1_HUMAN, P05000 (See protein sequence)
Recommended Name: Interferon omega-1 precursor  
Size: 195 amino acids; 22319 Da
1 PDB 3D structure from and Proteopedia for IFNW1:
3SE4 (3D)    
Secondary accessions: Q13168 Q5U802 Q5VWD0 Q7M4P5

Explore the universe of human proteins at neXtProt for IFNW1: NX_P05000

Explore proteomics data for IFNW1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn101

  • See IFNW1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_002168.1  
    ENSEMBL proteins: 
     ENSP00000369578  

    IFNW1 Human Recombinant Protein Products:

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    Novus Biologicals IFNW1 Lysates
    Sino Biological Recombinant Protein for IFNW1
    Sino Biological Cell Lysate for IFNW1
    ProSpec Recombinant Protein for IFNW1
    Browse Proteins at Cloud-Clone Corp.

     
    eBioscience Proteins for IFNW1:  
                        Recombinant Human IFN-omega 25 ug

    IFNW1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Search LSBio for Antibodies for IFNW1

    IFNW1 Assay Products:

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    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    eBioscience ELISAs for IFNW1: (see all 3
                        Human IFN-omega Platinum ELISA 96 tests


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    IFN: Interferons

    3 InterPro protein domains:
     IPR012351 4_helix_cytokine_core
     IPR000471 Interferon_alpha/beta/delta
     IPR009079 4_helix_cytokine-like_core

    Graphical View of Domain Structure for InterPro Entry P05000

    ProtoNet protein and cluster: P05000

    1 Blocks protein domain: IPB000471 Interferon alpha

    UniProtKB/Swiss-Prot: IFNW1_HUMAN, P05000
    Similarity: Belongs to the alpha/beta interferon family


    Find genes that share domains with IFNW1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for IFNW1:
    interferon type I,omega 1,leukocyte

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005125cytokine activity IBA--
    GO:0005126cytokine receptor binding TAS1647209
    GO:0005132type I interferon receptor binding IBA--
         
    Find genes that share ontologies with IFNW1           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IFNW1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for IFNW1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IFNW1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IFNW1

    miRNA
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    Block miRNA regulation of human, mouse, rat IFNW1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate IFNW1:
    hsa-miR-374c hsa-miR-655
    SwitchGear 3'UTR luciferase reporter plasmidIFNW1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for IFNW1
    Predesigned siRNA for gene silencing in human, mouse, rat IFNW1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for IFNW1

    Clone
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    OriGene clones in human, mouse for IFNW1 (see all 6)
    OriGene ORF clones in mouse, rat for IFNW1
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    GenScript: all cDNA clones in your preferred vector: IFNW1 (NM_002177)
    Sino Biological Human cDNA Clone for IFNW1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFNW1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFNW1

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for IFNW1
    Browse ESI BIO Cell Lines and PureStem Progenitors for IFNW1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNW1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IFNW1_HUMAN, P05000: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    lysosome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005615extracellular space IBA--

    Find genes that share ontologies with IFNW1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for IFNW1 About   (see all 6)  
    See pathways by source

    SuperPathContained pathways About
    1NOD-like Receptor Signaling Pathways
    Toll-Like receptor Signaling Pathways0.58
    NOD-like Receptor Signaling Pathways0.58
    2RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
    RIG-I-like receptor signaling pathway0.47
    3PEDF Induced Signaling
    Cytokine-cytokine receptor interaction0.43
    4Jak-STAT signaling pathway
    Jak-STAT signaling pathway
    5Interferon Pathway
    Interferon Pathway


    Find genes that share SuperPaths with IFNW1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 R&D Systems Pathways for IFNW1
        NOD-like Receptor Signaling Pathways
    Toll-Like receptor Signaling Pathways

    2 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for IFNW1
        Interferon Pathway
    all-trans-Retinoic Acid Mediated Apoptosis



    3 Kegg Pathways  (Kegg details for IFNW1):
        Cytokine-cytokine receptor interaction
    RIG-I-like receptor signaling pathway
    Jak-STAT signaling pathway

        Pathway & Disease-focused RT2 Profiler PCR Arrays including IFNW1: 
              Interferons & Receptors in human mouse rat
              Type I Interferon Response in human mouse rat
              Inflammatory Response & Autoimmunity 384HT in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for IFNW1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for IFNW1 (P050003 ENSP000003695784) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IFNAR1P171813, ENSP000002701394I2D: score=2 STRING: ENSP00000270139
    IFNAR2ENSP000003439574STRING: ENSP00000343957
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002250adaptive immune response IBA--
    GO:0002286T cell activation involved in immune response IBA--
    GO:0002323natural killer cell activation involved in immune response IBA--
    GO:0006952defense response ----
    GO:0006959humoral immune response IBA--

    Find genes that share ontologies with IFNW1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IFNW1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for IFNW1 gene: 
    NM_002177.1  

    Unigene Cluster for IFNW1:

    Interferon, omega 1
    Hs.73010
    Unigene Representative Sequence: NM_002177
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000380229(uc003zol.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat IFNW1 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate IFNW1:
    hsa-miR-374c hsa-miR-655
    SwitchGear 3'UTR luciferase reporter plasmidIFNW1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for IFNW1
    Predesigned siRNA for gene silencing in human, mouse, rat IFNW1
    Clone
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    OriGene clones in human, mouse for IFNW1 (see all 6)
    OriGene ORF clones in mouse, rat for IFNW1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IFNW1 (NM_002177)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFNW1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFNW1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for IFNW1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat IFNW1
      QuantiTect SYBR Green Assays in human, mouse, rat IFNW1
      QuantiFast Probe-based Assays in human, mouse, rat IFNW1

    Additional mRNA sequence: 

    AY780805.1 BC069095.1 BC117290.1 BC117292.1 X02669.1 

    1 DOTS entry:

    DT.407287 

    3 AceView cDNA sequences:

    NM_002177 X02669 BC069095 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IFNW1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGACTCTGGT
    IFNW1 Expression
    About this image


    IFNW1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
    IFNW1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IFNW1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.73010
        Pathway & Disease-focused RT2 Profiler PCR Arrays including IFNW1: 
              Interferons & Receptors in human mouse rat
              Type I Interferon Response in human mouse rat
              Inflammatory Response & Autoimmunity 384HT in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for IFNW1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat IFNW1
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    QuantiFast Probe-based Assays in human, mouse, rat IFNW1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNW1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for IFNW1 gene from Selected species (see all 2)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ifnz5 interferon zeta   --   4 (42.03 cM) 88782131 


    ENSEMBL Gene Tree for IFNW1 (if available)
    TreeFam Gene Tree for IFNW1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IFNW1 gene
    IFNA72  IFNA22  IFNA42  IFNE2  IFNA142  IFNA52  IFNK2  IFNA12  
    IFNA212  IFNA172  IFNA62  IFNB12  IFNA132  IFNA162  IFNA102  IFNA82  
    Selected SIMAP similar genes for IFNW1 using alignment to 1 protein entry:     IFNW1_HUMAN(see all similar genes):
    IFNA    IFNA10    IFNA17    IFNA2    IFNA8    IFNA21
    IFNA2B    IFNA4    IFNA5    IFNA7    IFN-2    IFNA14
    IFNA16    IFNA1    IFNA13    IFNA6    IFNB1    IFNE

    Find genes that share paralogs with IFNW1           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for IFNW1
    PGOHUM00000236408


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IFNW1 (see all 116)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1161607981,2
    F--21140149(+) ATTTCA/TTGTCT 1 -- ds50011Minor allele frequency- T:0.03WA 118
    rs1161903301,2
    C--21140199(+) TCAACA/GTCATT 1 -- ds50010--------
    rs1462501911,2
    --21140277(+) CGAAAC/TTGGTA 1 -- ds50010--------
    rs1823113271,2
    --21140430(+) GAGATA/GTTTTG 1 -- ds50010--------
    rs109648591,2
    C,F,H--21140672(+) TTTAAC/GCAAAT 1 -- ut3120Minor allele frequency- G:0.27NS EA NA WA CSA 2346
    rs1393779721,2
    C--21140678(+) CAAATC/GGAAAG 1 -- ut310--------
    rs1441428701,2
    C--21140711(+) ATACAA/GTGTAA 1 -- ut310--------
    rs1857978901,2
    --21140907(+) AAGCCA/GAAATA 1 -- ut310--------
    rs283681291,2
    C--21140944(-) ACTTGC/TACATG 1 -- ut31 ese30--------
    rs2002111531,2
    --21141020(+) CAGTCC/TTTCTT 2 R G mis10--------

    HapMap Linkage Disequilibrium report for IFNW1 (21140631 - 21142144 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for IFNW1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv892724CNV Gain21882294
    nsv892734CNV Gain21882294
    nsv892733CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IFNW1
    DNA2.0 Custom Variant and Variant Library Synthesis for IFNW1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 147553    OMIM disorders: --

    2 diseases for IFNW1:    
    About MalaCards
    dengue hemorrhagic fever    cutaneous malignant melanoma


    Find genes that share disorders with IFNW1           About GenesLikeMe

    Genetic Association Database (GAD): IFNW1
    Human Genome Epidemiology (HuGE) Navigator: IFNW1 (6 documents)

    Export disorders for IFNW1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IFNW1 gene, integrated from 10 sources (see all 30):
    (articles sorted by number of sources associating them with IFNW1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human interferon omega 1: isolation of the gene, expression in Chinese hamster ovary cells and characterization of the recombinant protein. (PubMed id 1647209)1, 2, 9 Adolf G.R....Zoephel A. (Biochim. Biophys. Acta 1991)
    2. Purification and characterization of natural human interferon omega 1. Two alternative cleavage sites for the signal peptidase. (PubMed id 1693148)1, 2, 9 Adolf G.R.... Cantell K. (J. Biol. Chem. 1990)
    3. Polymorphism discovery and association analyses of the interferon genes in type 1 diabetes. (PubMed id 16504056)1, 4, 9 Morris G.A....Todd J.A. (BMC Genet. 2006)
    4. Structural linkage between ligand discrimination and receptor activation by type I interferons. (PubMed id 21854986)1, 2 Thomas C.... Garcia K.C. (Cell 2011)
    5. Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. (PubMed id 20331378)1, 4 Mosbruger T.L....Thio C.L. (J. Infect. Dis. 2010)
    6. Dengue hemorrhagic fever is associated with polymorphisms in JAK1. (PubMed id 20588308)1, 4 Silva L.K....Teixeira M.G. (Eur. J. Hum. Genet. 2010)
    7. An approach based on a genome-wide association study reveals candidate loci for narcolepsy. (PubMed id 20677014)1, 4 Shimada M....Tokunaga K. (Hum. Genet. 2010)
    8. Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations. (PubMed id 20574843)1, 4 Yang X.R....Goldstein A.M. (Fam. Cancer 2010)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (Protein Sci. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3467 HGNC: 5448 AceView: IFNW1 Ensembl:ENSG00000177047 euGenes: HUgn3467
    ECgene: IFNW1 Kegg: 3467 H-InvDB: IFNW1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IFNW1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IFNW1 gene:
    Search GeneIP for patents involving IFNW1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     EMD Millipore genomic analysis products

      
     Antibodies for IFNW1 (IFN-omega)   Browse Cell Culture Products  
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     Block miRNA regulation of human, mouse, rat IFNW1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing IFNW1
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     QuantiFast Probe-based Assays in human, mouse, rat IFNW1 QuantiTect SYBR Green Assays in human, mouse, rat IFNW1
     PCR Arrays including human, mouse / rat IFNW1 Search Chromatin IP Primers for IFNW1
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat IFNW1  Search GeneGlobe Interaction Network for IFNW1
     Regulatory tfbs in IFNW1 promoter
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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     Browse ESI BIO Cell Lines and PureStem Progenitors for IFNW1
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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFNW1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IFNW1
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     Browse compounds at ApexBio
     Search Addgene for plasmids for IFNW1
     eBioscience proteins for IFNW1 (Recombinant Human IFN-omega 25 ug)
     eBioscience elisas for IFNW1 (Human IFN-omega Platinum ELISA 96 tests)
      eBioscience FlowRNA Probe Sets
           
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