Aliases for IFNL3 Gene
Aliases for IFNL3 Gene
External Ids for IFNL3 Gene
- HGNC: 18365
- Entrez Gene: 282617
- Ensembl: ENSG00000197110
- OMIM: 607402
- UniProtKB: Q8IZI9
Previous HGNC Symbols for IFNL3 Gene
- IL28B
Previous GeneCards Identifiers for IFNL3 Gene
- GC19M039735
Summaries for IFNL3 Gene
-
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
GeneCards Summary for IFNL3 Gene
IFNL3 (Interferon, Lambda 3) is a Protein Coding gene. Diseases associated with IFNL3 include Hepatitis C Virus and Ifnl3-Related Altered Drug Metabolism. Among its related pathways are Jak-STAT signaling pathway and Immune System. GO annotations related to this gene include receptor binding and cytokine activity. An important paralog of this gene is IFNL2.
UniProtKB/Swiss-Prot for IFNL3 Gene
-
Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IFNL3 Gene
Genomics for IFNL3 Gene
Regulatory Elements for IFNL3 Gene
Enhancers for IFNL3 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around IFNL3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for IFNL3 Gene
- Chromosome:
- 19
- Start:
- 39,243,553 bp from pter
- End:
- 39,247,034 bp from pter
- Size:
- 3,482 bases
- Orientation:
- Minus strand
Genomic View for IFNL3 Gene
Genes around IFNL3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.2 by Ensembl
- 19q13.13 by Entrez Gene
- 19q13.13 by HGNC
IFNL3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IFNL3 Gene
Proteins for IFNL3 Gene
-
Protein details for IFNL3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IZI9-IFNL3_HUMAN
- Recommended name:
- Interferon lambda-3
- Protein Accession:
- Q8IZI9
- A2BDE1
- Q6VN56
- Q7Z4J3
- Q8IWL6
Protein attributes for IFNL3 Gene
- Size:
- 196 amino acids
- Molecular mass:
- 21706 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAN28264.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Post-translational modifications for IFNL3 Gene
Other Protein References for IFNL3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for IFNL3 (IL-28A/B (IFN-lambda 2/3))
- R&D Systems Antibodies for IFNL3 (IL-28B/IFN-lambda 3)
-
Custom Antibody ServicesOriGene Antibodies for IFNL3
- Novus Biologicals Antibodies for IFNL3
- Abcam antibodies for IL28 + IL29
- Abcam antibodies for IL28B
-
Cloud-Clone Corp. Antibodies for IFNL3
- Invitrogen Antibodies for IFNL3
- antibodies-online Antibodies for IFNL3: See all 42
- GeneTex IFNL3 antibody for IFNL3
-
Custom Antibody ServicesProSci Antibodies for IFNL3
-
Santa Cruz Biotechnology (SCBT) Antibodies for IFNL3
Protein Products
- R&D Systems Proteins and Enzymes for IFNL3 (IL-28B/IFN-lambda 3)
-
OriGene Purified Proteins for IFNL3
- Search Origene for MassSpec and Protein Over-expression Lysates for IFNL3
- Origene Custom Protein Services for IFNL3
- Sino Biological Recombinant Proteins for IFNL3
- Sino Biological Cell Lysates for IFNL3
- antibodies-online Proteins for IFNL3: See all 22
- Search antibodies-online for peptides
- Search GeneTex for Proteins for IFNL3
- Abcam proteins for IL28B
Assay Products
- R&D Systems ELISAs and other biochemical assays for IFNL3 (IL-28B/IFN-lambda 3)
- antibodies-online Kits for IFNL3: See all 12
- Abcam assays for IL28
No data available for DME Specific Peptides for IFNL3 Gene
Domains & Families for IFNL3 Gene
Gene Families for IFNL3 Gene
- HGNC:
Protein Domains for IFNL3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for IFNL3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8IZI9- Family:
-
- Belongs to the lambda interferon family.
Function for IFNL3 Gene
Molecular function for IFNL3 Gene
- UniProtKB/Swiss-Prot Function:
- Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
- UniProtKB/Swiss-Prot Induction:
- By viral infections or double-stranded RNA.
Phenotypes for IFNL3 Gene
- GenomeRNAi human phenotypes for IFNL3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for IFNL3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
- Search ViGene Biosciences for IFNL3
CRISPR Products
-
OriGene CRISPR knockouts for IFNL3
-
Santa Cruz Biotechnology (SCBT) CRISPR for IFNL3
- GenScript: Design CRISPR guide RNA sequences for IFNL3
miRNA Products
- Search ViGene Biosciences for IFNL3
Inhibitory RNA Products
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for IFNL3
- Browse OriGene Inhibitory RNA Products For IFNL3
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
Clone Products
- OriGene clones in human for IFNL3
- OriGene ORF clones in human,mouse for IFNL3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for IFNL3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for IFNL3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for IFNL3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for IFNL3 Gene
Localization for IFNL3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for IFNL3 Gene
- Secreted.
No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for IFNL3 Gene
Pathways & Interactions for IFNL3 Gene
More details on SuperPathways for IFNL3Pathways by source for IFNL3 Gene
1 BioSystems pathway for IFNL3 Gene
3 Reactome pathways for IFNL3 Gene
1 PharmGKB pathway for IFNL3 Gene
2 KEGG pathways for IFNL3 Gene
4 R&D Systems pathways for IFNL3 Gene
1 Qiagen pathway for IFNL3 Gene
Interacting Proteins for IFNL3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0045071 | negative regulation of viral genome replication | ISS | -- |
| GO:0050778 | positive regulation of immune response | IEA | -- |
Transcripts for IFNL3 Gene
mRNA/cDNA for IFNL3 Gene
- (3) REFSEQ mRNAs :
- (6) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for IFNL3
-
Santa Cruz Biotechnology (SCBT) CRISPR for IFNL3
- GenScript: Design CRISPR guide RNA sequences for IFNL3
miRNA Products
- Search ViGene Biosciences for IFNL3
Inhibitory RNA Products
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for IFNL3
- Browse OriGene Inhibitory RNA Products For IFNL3
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
Clone Products
- OriGene clones in human for IFNL3
- OriGene ORF clones in human,mouse for IFNL3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for IFNL3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for IFNL3 Gene
mRNA differential expression in normal tissues according to GTEx for IFNL3 Gene
This gene is overexpressed in Testis (x9.2), Brain - Cerebellum (x5.7), Brain - Cortex (x4.5), Whole Blood (x4.4), and Brain - Cerebellar Hemisphere (x4.0).
SOURCE GeneReport for Unigene cluster for IFNL3 Gene Hs.406744
Primer Products
-
OriGene qPCR primer pairs for IFNL3
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for IFNL3 Gene
Orthologs for IFNL3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | LOC100298542 35 |
|
||
| -- 36 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | LOC612543 35 |
|
||
| -- 36 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Ifnl2 35 |
|
||
| Ifnl3 16 |
|
||||
| Ifnl2 36 |
|
ManyToMany | |||
| Ifnl3 36 |
|
ManyToMany | |||
| chimpanzee (Pan troglodytes) |
Mammalia | IL28B 35 |
|
||
| IFNL3 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | LOC100911249 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 36 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | IL28B 35 |
|
||
| IFNL 36 |
|
ManyToMany | |||
| IFNL 36 |
|
ManyToMany |
- Species with no ortholog for IFNL3:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for IFNL3 Gene
(2) SIMAP similar genes for IFNL3 Gene using alignment to 1 proteins:
Pseudogenes.org Pseudogenes for IFNL3 Gene
Variants for IFNL3 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs629976 | - | 39,244,885(-) | GCTCC(A/G)CGGGG | reference, missense | |
| rs8103142 | - | 39,244,466(+) | GGCAC(C/T)TGCAG | reference, missense | |
| rs8102358 | -- | 39,244,372(+) | CAGGT(A/G)AGCAG | intron-variant | |
| rs67461793 | -- | 39,245,671(+) | TATAT(-/AT)TTTGA | intron-variant, upstream-variant-2KB | |
| rs71169578 | -- | 39,243,216(+) | TTTAC(-/T)TTTTT | downstream-variant-500B |
Residual Variation Intolerance Score:
98.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.99;
74.84% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for IFNL3 Gene
- Human Gene Mutation Database (HGMD)
- IFNL3
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for IFNL3 Gene
Disorders for IFNL3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hepatitis c virus |
|
|
| ifnl3-related altered drug metabolism |
|
|
| response to antiviral treatment in hepatitis c |
|
|
| cryoglobulinemic vasculitis |
|
|
| drug-induced hepatitis |
|
|
Search IFNL3 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for IFNL3
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- IFNL3
No data available for UniProtKB/Swiss-Prot and Genatlas for IFNL3 Gene
Publications for IFNL3 Gene
- Liposome-mediated IL-28 and IL-29 expression in A549 cells and anti- viral effect of IL-28 and IL-29 on WISH cells. (PMID: 16539846) Li M.C. … He S.H. (Acta Pharmacol. Sin. 2006) 3 4 23 67
- Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients. (PMID: 20389235) RallA^n N.I. … Soriano V. (AIDS 2010) 3 23
- Human interferon-lambda3 is a potent member of the type III interferon family. (PMID: 18987645) Dellgren C. … Hartmann R. (Genes Immun. 2009) 3 23
- Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. (PMID: 19684573) Ge D. … Goldstein D.B. (Nature 2009) 3 23
- IL-28, IL-29 and their class II cytokine receptor IL-28R. (PMID: 12469119) Sheppard P. … Klucher K.M. (Nat. Immunol. 2003) 3 23
Products for IFNL3 Gene
- R&D Systems Antibodies for IFNL3 (IL-28A/B (IFN-lambda 2/3))
- R&D Systems Antibodies for IFNL3 (IL-28B/IFN-lambda 3)
- R&D Systems Proteins and Enzymes for IFNL3 (IL-28B/IFN-lambda 3)
- R&D Systems ELISAs and other biochemical assays for IFNL3 (IL-28B/IFN-lambda 3)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for IFNL3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for IFNL3
- Search Origene for MassSpec and Protein Over-expression Lysates for IFNL3
- Origene Custom Protein Services for IFNL3
- Origene siRNA, shRNA, mouse_rna, and RNAi products in human, mouse, rat for IFNL3
- Browse OriGene Inhibitory RNA Products For IFNL3
- OriGene qPCR primer pairs for IFNL3
- OriGene CRISPR knockouts for IFNL3
- OriGene clones in human for IFNL3
- OriGene ORF clones in human,mouse for IFNL3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for IFNL3
- GenScript Custom Assay Services for IFNL3
- GenScript Custom overexpressing Cell Line Services for IFNL3
- GenScript: Design CRISPR guide RNA sequences for IFNL3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for IFNL3
- Sino Biological Human cDNA Clone for IFNL3
- Sino Biological Cell Lysates for IFNL3
- Sino Biological Recombinant Proteins for IFNL3
- 4000+ Proteins
- Search Sino Biological for antibodies, proteins & pathways
- Protein Production Services
- Transfection Reagents
- Protein A/G/L resins
- Isotyping reagents
- Novus Biologicals Antibodies for IFNL3
- Novus Biologicals proteins and lysates for IFNL3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for IL28B
- Abcam antibodies for IL28 + IL29
- Abcam proteins for IL28B
- Abcam assays for IL28
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- Cloud-Clone Corp. Antibodies for IFNL3
- Browse Proteins at Cloud-Clone Corp.
- antibodies-online Antibodies for IFNL3: See all 42
- antibodies-online Kits for IFNL3: See all 12
- antibodies-online Proteins for IFNL3: See all 22
- Search antibodies-online for peptides
- GeneTex IFNL3 antibody for IFNL3
- Search GeneTex for Proteins for IFNL3
- ViGene Biosciences adenoviral particle packaged cDNA for IFNL3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for IFNL3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for IFNL3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
- Search ViGene Biosciences for IFNL3
- Search ViGene Biosciences for IFNL3
- Santa Cruz Biotechnology (SCBT) Antibodies for IFNL3
- Search Santa Cruz Biotechnology (SCBT) for IFNL3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for IFNL3
- Custom Antibody ServicesProSci Antibodies for IFNL3
Sources for IFNL3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon