Aliases for IFNL3 Gene
Aliases for IFNL3 Gene
External Ids for IFNL3 Gene
- HGNC: 18365
- Entrez Gene: 282617
- Ensembl: ENSG00000197110
- OMIM: 607402
- UniProtKB: Q8IZI9
Previous HGNC Symbols for IFNL3 Gene
- IL28B
Previous GeneCards Identifiers for IFNL3 Gene
- GC19M039735
Summaries for IFNL3 Gene
-
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). [provided by RefSeq, Jul 2008]
GeneCards Summary for IFNL3 Gene
IFNL3 (Interferon Lambda 3) is a Protein Coding gene. Diseases associated with IFNL3 include Hepatitis C Virus and Ifnl3-Related Altered Drug Metabolism. Among its related pathways are Immune System and Toll-Like receptor Signaling Pathways. GO annotations related to this gene include receptor binding and cytokine activity. An important paralog of this gene is IFNL2.
UniProtKB/Swiss-Prot for IFNL3 Gene
-
Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IFNL3 Gene
Genomics for IFNL3 Gene
Regulatory Elements for IFNL3 Gene
Enhancers for IFNL3 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH19F039892 | 0.8 | Ensembl | 5.2 | -646.6 | -646639 | 1.9 | CEBPG ZNF366 SCRT2 KLF7 KLF8 EGR2 SCRT1 ZNF362 NRF1 NR2F1 | IFNL3 GC19M039890 FCGBP |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around IFNL3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for IFNL3 Gene
- Chromosome:
- 19
- Start:
- 39,243,553 bp from pter
- End:
- 39,247,034 bp from pter
- Size:
- 3,482 bases
- Orientation:
- Minus strand
Genomic View for IFNL3 Gene
Genes around IFNL3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.2 by Ensembl
- 19q13.2 by Entrez Gene
- 19q13.2 by HGNC
IFNL3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for IFNL3 Gene
Proteins for IFNL3 Gene
-
Protein details for IFNL3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IZI9-IFNL3_HUMAN
- Recommended name:
- Interferon lambda-3
- Protein Accession:
- Q8IZI9
- A2BDE1
- Q6VN56
- Q7Z4J3
- Q8IWL6
Protein attributes for IFNL3 Gene
- Size:
- 196 amino acids
- Molecular mass:
- 21706 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAN28264.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Post-translational modifications for IFNL3 Gene
Other Protein References for IFNL3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for IFNL3 (IL-28A/B (IFN-lambda 2/3))
- R&D Systems Antibodies for IFNL3 (IL-28B/IFN-lambda 3)
-
Custom Antibody ServicesOriGene Antibodies for IFNL3
- Novus Biologicals Antibodies for IFNL3
-
Abcam antibodies for IFNL3
- Invitrogen Antibodies for IFNL3
- antibodies-online Antibodies for IFNL3: See all 42
- GeneTex IFNL3 antibody for IFNL3
-
St John's Laboratory Antibodies for IFNL3
-
Custom Antibody ServicesProSci Antibodies for IFNL3
-
Santa Cruz Biotechnology (SCBT) Antibodies for IFNL3
Protein Products
- R&D Systems Proteins and Enzymes for IFNL3 (IL-28B/IFN-lambda 3)
-
OriGene Purified Proteins for IFNL3
- Search Origene for MassSpec and Protein Over-expression Lysates for IFNL3
- Origene Custom Protein Services for IFNL3
- Sino Biological Recombinant Proteins for IFNL3
- Sino Biological Cell Lysates for IFNL3
- antibodies-online Proteins for IFNL3: See all 22
- Search antibodies-online for peptides
- Search GeneTex for Proteins for IFNL3
-
Abcam proteins for IFNL3
Assay Products
- R&D Systems ELISAs, Luminex Assays, and other biochemical assays for IFNL3 (IL-28B/IFN-lambda 3)
- antibodies-online Kits for IFNL3: See all 12
-
Abcam assays for IFNL3
No data available for DME Specific Peptides for IFNL3 Gene
Domains & Families for IFNL3 Gene
Gene Families for IFNL3 Gene
- HGNC:
Protein Domains for IFNL3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for IFNL3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8IZI9- Family:
-
- Belongs to the lambda interferon family.
Function for IFNL3 Gene
Molecular function for IFNL3 Gene
- UniProtKB/Swiss-Prot Function:
- Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
- UniProtKB/Swiss-Prot Induction:
- By viral infections or double-stranded RNA.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005102 | receptor binding | IBA | -- |
| GO:0005125 | cytokine activity | IEA | -- |
Phenotypes for IFNL3 Gene
- MGI mutant phenotypes for IFNL3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for IFNL3:
Animal Models for IFNL3 Gene
- MGI Knock Outs for IFNL3:
-
- Ifnl3 tm1.1(KOMP)Vlcg
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for IFNL3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for IFNL3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
- Search ViGene Biosciences for IFNL3
CRISPR Products
-
OriGene CRISPR knockouts for IFNL3
- GenScript: Design CRISPR guide RNA sequences for IFNL3
miRNA Products
- Search ViGene Biosciences for IFNL3
Inhibitory RNA Products
- Origene shRNA, siRNA, mouse_rna, and RNAi products in human, mouse, rat for IFNL3
- Browse OriGene Inhibitory RNA Products For IFNL3
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
Clone Products
- Sino Biological Human cDNA Clone for IFNL3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IFNL3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IFNL3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for IFNL3
-
ViGene Biosciences adenoviral particle packaged cDNA for IFNL3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for IFNL3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for IFNL3 Gene
Localization for IFNL3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for IFNL3 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytosol | 2 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | IEA,IBA | -- |
| GO:0005622 | intracellular | IEA | -- |
Pathways & Interactions for IFNL3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Jak-STAT signaling pathway (KEGG) | ||
| 2 | RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways | ||
| 3 | Toll-Like receptor Signaling Pathways | ||
| 4 | Cytokine Signaling in Immune system | ||
| 5 | PEDF Induced Signaling | ||
Pathways by source for IFNL3 Gene
1 BioSystems pathway for IFNL3 Gene
3 Reactome pathways for IFNL3 Gene
1 PharmGKB pathway for IFNL3 Gene
2 KEGG pathways for IFNL3 Gene
4 R&D Systems pathways for IFNL3 Gene
1 Qiagen pathway for IFNL3 Gene
Interacting Proteins for IFNL3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007259 | JAK-STAT cascade | IEA | -- |
| GO:0045071 | negative regulation of viral genome replication | ISS | -- |
| GO:0045087 | innate immune response | IBA | -- |
| GO:0050778 | positive regulation of immune response | IEA | -- |
| GO:0050863 | regulation of T cell activation | IBA | -- |
Transcripts for IFNL3 Gene
mRNA/cDNA for IFNL3 Gene
- (3) REFSEQ mRNAs :
- (6) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for IFNL3
- GenScript: Design CRISPR guide RNA sequences for IFNL3
miRNA Products
- Search ViGene Biosciences for IFNL3
Inhibitory RNA Products
- Origene shRNA, siRNA, mouse_rna, and RNAi products in human, mouse, rat for IFNL3
- Browse OriGene Inhibitory RNA Products For IFNL3
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
Clone Products
- Sino Biological Human cDNA Clone for IFNL3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IFNL3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IFNL3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for IFNL3 Gene
mRNA differential expression in normal tissues according to GTEx for IFNL3 Gene
This gene is overexpressed in Testis (x9.2), Brain - Cerebellum (x5.7), Brain - Cortex (x4.5), Whole Blood (x4.4), and Brain - Cerebellar Hemisphere (x4.0).
NURSA nuclear receptor signaling pathways regulating expression of IFNL3 Gene:
IFNL3SOURCE GeneReport for Unigene cluster for IFNL3 Gene:
Hs.406744Primer Products
-
OriGene qPCR primer pairs for IFNL3
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for IFNL3 Gene
Orthologs for IFNL3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | IL28B 34 |
|
||
| IFNL3 35 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | LOC612543 34 |
|
||
| -- 35 |
|
OneToMany | |||
| cow (Bos Taurus) |
Mammalia | LOC100298542 34 |
|
||
| -- 35 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Ifnl2 34 35 |
|
||
| Ifnl3 16 35 |
|
||||
| rat (Rattus norvegicus) |
Mammalia | LOC100911249 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | IL28B 34 |
|
||
| IFNL 35 35 |
|
ManyToMany |
- Species where no ortholog for IFNL3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for IFNL3 Gene
(2) SIMAP similar genes for IFNL3 Gene using alignment to 1 proteins:
Pseudogenes.org Pseudogenes for IFNL3 Gene
Variants for IFNL3 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs112885693 | -- | 39,244,316(+) | GGGGA(A/G)AGGAG | intron-variant | |
| rs112990542 | -- | 39,243,537(+) | TTTAC(A/G)TACAC | downstream-variant-500B, utr-variant-3-prime | |
| rs113249739 | -- | 39,246,682(+) | ATCCC(G/T)CATGG | nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime | |
| rs113703374 | -- | 39,245,523(+) | ACTCT(A/G)TCACT | upstream-variant-2KB | |
| rs114424160 | -- | 39,247,046(+) | TGAGA(G/T)CCTCG | nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime |
Residual Variation Intolerance Score:
98.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.99;
74.84% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for IFNL3 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for IFNL3 Gene
Disorders for IFNL3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hepatitis c virus |
|
|
| ifnl3-related altered drug metabolism |
|
|
| htlv-1 associated myelopathy/tropical spastic paraparesis |
|
|
| med23 |
|
|
| drug-induced hepatitis |
|
|
Search IFNL3 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for IFNL3
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- IFNL3
No data available for UniProtKB/Swiss-Prot and Genatlas for IFNL3 Gene
Publications for IFNL3 Gene
- Liposome-mediated IL-28 and IL-29 expression in A549 cells and anti- viral effect of IL-28 and IL-29 on WISH cells. (PMID: 16539846) Li M.C. … He S.H. (Acta Pharmacol. Sin. 2006) 3 4 22 64
- IL-28, IL-29 and their class II cytokine receptor IL-28R. (PMID: 12469119) Sheppard P. … Klucher K.M. (Nat. Immunol. 2003) 3 4 22 64
- IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. (PMID: 12483210) Kotenko S.V. … Donnelly R.P. (Nat. Immunol. 2003) 3 4 22 64
- Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients. (PMID: 20389235) RallA^n N.I. … Soriano V. (AIDS 2010) 3 22 64
- Human interferon-lambda3 is a potent member of the type III interferon family. (PMID: 18987645) Dellgren C. … Hartmann R. (Genes Immun. 2009) 3 22 64
Products for IFNL3 Gene
- R&D Systems Antibodies for IFNL3 (IL-28A/B (IFN-lambda 2/3))
- R&D Systems Antibodies for IFNL3 (IL-28B/IFN-lambda 3)
- R&D Systems Proteins and Enzymes for IFNL3 (IL-28B/IFN-lambda 3)
- R&D Systems ELISAs, Luminex Assays, and other biochemical assays for IFNL3 (IL-28B/IFN-lambda 3)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for IFNL3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for IFNL3
- Search Origene for MassSpec and Protein Over-expression Lysates for IFNL3
- Origene Custom Protein Services for IFNL3
- Origene shRNA, siRNA, mouse_rna, and RNAi products in human, mouse, rat for IFNL3
- Browse OriGene Inhibitory RNA Products For IFNL3
- OriGene qPCR primer pairs for IFNL3
- OriGene CRISPR knockouts for IFNL3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For IFNL3
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for IFNL3
- GenScript Custom Assay Services for IFNL3
- GenScript Custom overexpressing Cell Line Services for IFNL3
- GenScript: Design CRISPR guide RNA sequences for IFNL3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for IFNL3
- Sino Biological Human cDNA Clone for IFNL3
- Sino Biological Recombinant Proteins for IFNL3
- Sino Biological Cell Lysates for IFNL3
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for IFNL3
- Novus Biologicals proteins and lysates for IFNL3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for IFNL3
- Abcam proteins for IFNL3
- Abcam assays for IFNL3
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- antibodies-online Antibodies for IFNL3: See all 42
- antibodies-online Kits for IFNL3: See all 12
- antibodies-online Proteins for IFNL3: See all 22
- Search antibodies-online for peptides
- GeneTex IFNL3 antibody for IFNL3
- Search GeneTex for Proteins for IFNL3
- ViGene Biosciences adenoviral particle packaged cDNA for IFNL3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for IFNL3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for IFNL3 gene
- Search ViGene Biosciences for IFNL3
- Santa Cruz Biotechnology (SCBT) Antibodies for IFNL3
- Search Santa Cruz Biotechnology (SCBT) for IFNL3 siRNA/shRNA
- Browse Santa Cruz Biotechnology (SCBT) for IFNL3 CRISPR
- Custom Antibody ServicesProSci Antibodies for IFNL3
- Horizon Cell Lines for IFNL3
- Cyagen custom Knockout/knockin (KOKI) mouse models for IFNL3
- VectorBuilder custom plasmid, inducible vectors for IFNL3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IFNL3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for IFNL3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab