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IFNL1 Gene

protein-coding   GIFtS: 44
GCID: GC19P039787

Interferon, Lambda 1

(Previous names: interleukin 29, interleukin 29 (interferon, lambda 1))
(Previous symbol: IL29)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Interferon, Lambda 11 2     Interleukin 291
IL291 2 3 5     Interferon Lambda-12
Interleukin 29 (Interferon, Lambda 1)1 2     interferon-lambda-12
Cytokine Zcyto212 3     interleukin-292
IFN-lambda-12 3     Interleukin-293
IL-292 3     ZCYTO213

External Ids:    HGNC: 183631   Entrez Gene: 2826182   Ensembl: ENSG000001823937   OMIM: 6074035   UniProtKB: Q8IU543   

Export aliases for IFNL1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for IFNL1 Gene:
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin
28A (IL28A), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene
cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be
induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II
cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha
(IL28RA). (provided by RefSeq, Jul 2008)

GeneCards Summary for IFNL1 Gene:
IFNL1 (interferon, lambda 1) is a protein-coding gene. GO annotations related to this gene include interleukin-28 receptor binding and receptor binding. An important paralog of this gene is IFNL2.

UniProtKB/Swiss-Prot: IFNL1_HUMAN, Q8IU54
Function: Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I
antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The
ligand/receptor complex seems to signal through the Jak-STAT pathway

Gene Wiki entry for IFNL1 (Interleukin 29) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011109.17  
Regulatory elements:
   Search for regulatory transcription factor binding sites for IFNL1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIFNL1 promoter sequence
   Search Chromatin IP Primers for IFNL1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IFNL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.13   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.13

IFNL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFNL1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P039787:  view genomic region     (about GC identifiers)

Start:
39,786,965 bp from pter      End:
39,789,313 bp from pter
Size:
2,349 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: IFNL1_HUMAN, Q8IU54 (See protein sequence)
Recommended Name: Interferon lambda-1 precursor  
Size: 200 amino acids; 21898 Da
2 PDB 3D structures from and Proteopedia for IFNL1:
3OG4 (3D)        3OG6 (3D)    
Secondary accessions: A0AV25 Q17R34

Explore the universe of human proteins at neXtProt for IFNL1: NX_Q8IU54

Explore proteomics data for IFNL1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn65

  • See IFNL1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_742152.1  
    ENSEMBL proteins: 
     ENSP00000329991  

    IFNL1 Human Recombinant Protein Products:

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    Sino Biological Cell Lysate for IFNL1
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    Browse Proteins at Cloud-Clone Corp.

     
    eBioscience Proteins for IFNL1: (see all 3
                        Human IL-29 (IFN lambda 1) Recombinant Protein 25 ug

     
    antibodies-online proteins for IFNL1 (28 products) 

     
    antibodies-online peptides for IFNL1

    IFNL1 Antibody Products:

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    antibodies-online antibodies for IFNL1 (35 products) 

    IFNL1 Assay Products:

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    eBioscience ELISAs for IFNL1: (see all 2
                        Human IL-29 (IFN lambda 1) ELISA Ready-SET-Go! 20 x 96 tests
    antibodies-online kits for IFNL1 (19 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    IFN: Interferons

    ProtoNet protein and cluster: Q8IU54

    UniProtKB/Swiss-Prot: IFNL1_HUMAN, Q8IU54
    Similarity: Belongs to the lambda interferon family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IFNL1_HUMAN, Q8IU54
    Function: Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I
    antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The
    ligand/receptor complex seems to signal through the Jak-STAT pathway
    Induction: By viral infections or double-stranded RNA

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005102receptor binding IDA12483210
    GO:0005125cytokine activity IEA--
    GO:0032003interleukin-28 receptor binding IPI12469119
         
    Find genes that share ontologies with IFNL1           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for IFNL1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNL1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IFNL1_HUMAN, Q8IU54: Secreted

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IDA12483210
    GO:0005615extracellular space IEA--
    GO:0032002interleukin-28 receptor complex IDA12469119

    Find genes that share ontologies with IFNL1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for IFNL1 About    
    See pathways by source

    SuperPathContained pathways About
    1Jak-STAT signaling pathway
    Jak-STAT signaling pathway
    Type III interferon signaling0.00
    2NOD-like Receptor Signaling Pathways
    Toll-Like receptor Signaling Pathways0.58
    3PEDF Induced Signaling
    Cytokine-cytokine receptor interaction0.43


    Find genes that share SuperPaths with IFNL1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 R&D Systems Pathway for IFNL1
        Toll-Like receptor Signaling Pathways

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for IFNL1
        all-trans-Retinoic Acid Mediated Apoptosis

    1 BioSystems Pathway for IFNL1
        Type III interferon signaling



    2 Kegg Pathways  (Kegg details for IFNL1):
        Cytokine-cytokine receptor interaction
    Jak-STAT signaling pathway

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IFNL1
    Interactions:

        Search GeneGlobe Interaction Network for IFNL1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for IFNL1 (Q8IU543 ENSP000003299914) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IFNLR1Q8IU573, ENSP000003278244I2D: score=1 STRING: ENSP00000327824
    IL10RBENSP000002902004STRING: ENSP00000290200
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002829negative regulation of type 2 immune response IDA19346497
    GO:0008285negative regulation of cell proliferation IDA15166220
    GO:0032696negative regulation of interleukin-13 production IDA19346497
    GO:0032714negative regulation of interleukin-5 production IDA19346497
    GO:0032729positive regulation of interferon-gamma production IDA19346497

    Find genes that share ontologies with IFNL1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IFNL1

    1 Novoseek inferred chemical compound relationship for IFNL1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    2',5'-oligoadenylate 64.3 2 17006906 (1), 18657576 (1)



    Find genes that share compounds with IFNL1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for IFNL1 gene: 
    NM_172140.1  

    Unigene Cluster for IFNL1:

    Interferon, lambda 1
    Hs.406745
    Unigene Representative Sequence: AY129150
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000333625(uc002okv.3)
    miRNA
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat IFNL1
      QuantiFast Probe-based Assays in human, mouse, rat IFNL1

    Additional mRNA sequence: 

    AY129150.1 AY184372.1 AY336716.1 BC074985.2 BC117482.1 BC126183.1 HQ214053.1 JF268782.1 

    1 DOTS entry:

    DT.100013335 

    6 AceView cDNA sequences:

    BC074985 AY336716 AY184372 NM_172140 AY129150 T07139 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IFNL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    IFNL1 Expression
    About this image

    IFNL1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IFNL1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.406745
        Custom PCR Arrays for IFNL1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for IFNL1 gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia IL29L6
    --
    Uncharacterized protein
    73(a)
    71(a)
    many → 1
    many → 1
    24(36440445-36441017)
    1(113905414-113907467)
    chicken
    (Gallus gallus)
    Aves IFNL6
    IFNL6
    Gallus gallus interleukin 28B (interferon, lambda ...
    Gallus gallus interleukin 28B (interferon, lambda ...
    32(a)
    32(a)
    many ↔ many
    many ↔ many
    AADN03020056.1(8264-9772)
    AADN03016676.1(2617-4124)


    ENSEMBL Gene Tree for IFNL1 (if available)
    TreeFam Gene Tree for IFNL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IFNL1 gene
    IFNL22  IFNL32  
    2 SIMAP similar genes for IFNL1 using alignment to 1 protein entry:     IFNL1_HUMAN:
    IFNL3    IFNL2

    Find genes that share paralogs with IFNL1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IFNL1 (see all 152)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1455310351,2
    C--39785140(+) TAGAT-/GATA  
            
    GATAG
    1 -- us2k10--------
    rs802217571,2
    C--39785142(+) ATAGA-/TAGA  
            
    GAGAT
    1 -- us2k10--------
    rs106381741,2
    C--39785188(+) TAGAT-/A/A   
      G
    /AGAG
    agaga
    1 -- us2k1 trp30--------
    rs788429781,2
    C--39785192(+) ATAGAT/GAGAGA 1 -- us2k11Minor allele frequency- G:0.00NA 2
    rs757263441,2
    C--39785196(+) AGAGAT/GAGAGA 1 -- us2k11Minor allele frequency- G:0.00NA 2
    rs747566381,2
    C--39785200(+) AGAGAG/CAGAGA 1 -- us2k11Minor allele frequency- C:0.50NA 2
    rs3686168441,2
    C--39785222(+) AGAGA-/CTAG  
      ATAGAT
    GAGAG
    1 -- us2k10--------
    rs1432072251,2
    --39785355(+) AGTTCC/TAGAAT 1 -- us2k10--------
    rs621228821,2
    C,F--39785360(+) CAGAAT/CAAAAG 1 -- us2k16Minor allele frequency- C:0.30WA NA CSA 246
    rs735440981,2
    C,F--39785446(+) CCAGGC/ATGGAG 1 -- us2k12Minor allele frequency- A:0.50WA 4

    HapMap Linkage Disequilibrium report for IFNL1 (39786965 - 39789313 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for IFNL1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IFNL1
    DNA2.0 Custom Variant and Variant Library Synthesis for IFNL1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607403    OMIM disorders: --


    Find genes that share disorders with IFNL1           About GenesLikeMe

    5 Novoseek inferred disease relationships for IFNL1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    virus infection 37.7 2 12469119 (1), 16537619 (1)
    influenza 22.2 9 16014923 (4), 16537619 (2), 19155475 (1), 16797201 (1)
    autoimmunity 12.9 1 17027516 (1)
    necrosis 0 4 16014923 (1), 16227300 (1), 16603509 (1), 16537619 (1)
    tumors 0 5 16650825 (2), 16014923 (1), 16227300 (1), 16537619 (1)


    Export disorders for IFNL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IFNL1 gene, integrated from 10 sources (see all 93):
    (articles sorted by number of sources associating them with IFNL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. IL-28, IL-29 and their class II cytokine receptor IL-28R. (PubMed id 12469119)1, 2, 9 Sheppard P.... Klucher K.M. (Nat. Immunol. 2003)
    2. IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex. (PubMed id 12483210)1, 2, 9 Kotenko S.V.... Donnelly R.P. (Nat. Immunol. 2003)
    3. Crystal structure of human interferon-lambda1 in complex with its high-affinity receptor interferon-lambdaR1. (PubMed id 20934432)1, 2 Miknis Z.J....Wlodawer A. (J. Mol. Biol. 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Liposome-mediated IL-28 and IL-29 expression in A549 cells and anti- viral effect of IL-28 and IL-29 on WISH cells. (PubMed id 16539846)1, 9 Li M.C.... He S.H. (Acta Pharmacol. Sin. 2006)
    6. IFN-lambda1 (IL-29) inhibits GATA3 expression and suppresses Th2 responses in human naive and memory T cells. (PubMed id 19346497)1, 9 Dai J....Gallagher G. (Blood 2009)
    7. Differentiated human alveolar type II cells secrete antiviral IL-29 (IFN-lambda 1) in response to influenza A infection. (PubMed id 19155475)1, 9 Wang J....Mason R.J. (J. Immunol. 2009)
    8. Interferon lambda-1 (IFN-lambda1/IL-29) induces ELR(-) CXC chemokine mRNA in human peripheral blood mononuclear cells, in an IFN-gamma-independent manner. (PubMed id 17252004)1, 9 Pekarek V....Gallagher G. (Genes Immun. 2007)
    9. Interleukin-29 binds to melanoma cells inducing Jak-STAT signal transduction and apoptosis. (PubMed id 20103601)1, 9 Guenterberg K.D....Carson W.E. (Mol. Cancer Ther. 2010)
    10. Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells. (PubMed id 16014923)1, 9 Osterlund P....Julkunen I. (J. Virol. 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 282618 HGNC: 18363 AceView: IL29 Ensembl:ENSG00000182393 euGenes: HUgn282618
    ECgene: IFNL1 Kegg: 282618 H-InvDB: IFNL1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IFNL1 Pharmacogenomics, SNPs, Pathways
    Wikipedia http://en.wikipedia.org/wiki/Interleukin_29

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IFNL1 gene:
    Search GeneIP for patents involving IFNL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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