Aliases for IFNGR1 Gene
External Ids for IFNGR1 Gene
Previous Symbols for IFNGR1 Gene
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]
GeneCards Summary for IFNGR1 Gene
IFNGR1 (Interferon Gamma Receptor 1) is a Protein Coding gene. Diseases associated with IFNGR1 include mycobacterium avium complex disease and coccidioidomycosis. Among its related pathways are TGF-Beta Pathway and Interferon Pathway. GO annotations related to this gene include cytokine binding and interferon-gamma receptor activity.
UniProtKB/Swiss-Prot for IFNGR1 Gene
Receptor for interferon gamma. Two receptors bind one interferon gamma dimer