Aliases for IFNG Gene
External Ids for IFNG Gene
- HGNC: 5438
- Entrez Gene: 3458
- Ensembl: ENSG00000111537
- OMIM: 147570
- UniProtKB: P01579
Previous GeneCards Identifiers for IFNG Gene
- GC12M068352
- GC12M068265
- GC12M066834
- GC12M068548
- GC12M065599
Summaries for IFNG Gene
-
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]
GeneCards Summary for IFNG Gene
IFNG (Interferon Gamma) is a Protein Coding gene. Diseases associated with IFNG include Tuberous Sclerosis 2 and Hepatitis C Virus. Among its related pathways are Bacterial infections in CF airways and Toll-like receptor signaling pathway. Gene Ontology (GO) annotations related to this gene include cytokine activity and interferon-gamma receptor binding.
UniProtKB/Swiss-Prot for IFNG Gene
-
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Additional gene information for IFNG Gene
- Monarch Initiative
- Search for IFNG at DataMed
- Search for IFNG at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for IFNG Gene
Genomics for IFNG Gene
GeneHancer (GH) Regulatory Elements for IFNG Gene
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH12I068158 | Promoter/Enhancer | 1.1 | EPDnew ENCODE | 550.8 | +0.1 | 118 | 1.5 | CTCF EBF1 DPF2 ZNF217 IKZF1 ATF7 RUNX3 IKZF2 | GC12M068160 GC12M068159 IFNG GC12P068143 IFNG-AS1 | |
GH12I068159 | Enhancer | 0.5 | ENCODE | 550.8 | +1.1 | 1111 | 0.2 | CTCF ZNF654 REST RAD21 | GC12M068159 GC12M068160 IFNG GC12P068143 IFNG-AS1 | |
GH12I068480 | Enhancer | 1.5 | FANTOM5 Ensembl ENCODE dbSUPER | 13.3 | -322.9 | -322862 | 3.4 | PKNOX1 ATF1 BMI1 BATF IRF4 ETV6 ATF7 IKZF2 RUNX3 CBFB | LINC02384 IFNG NUP107 ENSG00000256917 PSMC6P2 | |
GH12I067988 | Enhancer | 1.4 | FANTOM5 Ensembl ENCODE dbSUPER | 4.2 | +168.9 | 168918 | 4.8 | PKNOX1 FOXA2 EBF1 BATF RELA GATA3 POLR2A ATF7 IKZF2 RUNX3 | IFNG-AS1 LINC01479 IFNG IL22 DYRK2 GC12P067986 RPL39P28 | |
GH12I068080 | Enhancer | 0.4 | ENCODE | 11.6 | +78.9 | 78940 | 0.7 | IKZF1 RUNX3 | IFNG IFNG-AS1 GC12P068096 HNRNPA1P70 |
Regulatory Element Products
Genomic Locations for IFNG Gene
- chr12:68,154,768-68,159,747
- (GRCh38/hg38)
- Size:
- 4,980 bases
- Orientation:
- Minus strand
- chr12:68,548,548-68,553,527
- (GRCh37/hg19)
Genomic View for IFNG Gene
- Cytogenetic band:
-
- 12q15 by Ensembl
- 12q15 by Entrez Gene
- 12q15 by HGNC


RefSeq DNA sequence for IFNG Gene
Proteins for IFNG Gene
-
Protein details for IFNG Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P01579-IFNG_HUMAN
- Recommended name:
- Interferon gamma
- Protein Accession:
- P01579
- B5BU88
- Q53ZV4
Protein attributes for IFNG Gene
- Size:
- 166 amino acids
- Molecular mass:
- 19348 Da
- Quaternary structure:
-
- Homodimer.
Protein Expression for IFNG Gene
Post-translational modifications for IFNG Gene
- Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.
- Glycosylation at posLast=4848 and isoforms=120
Other Protein References for IFNG Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for IFNG (IFN-gamma)
- Cell Signaling Technology (CST) Antibodies for IFNG (IFNG)
-
Custom Antibody ServicesOriGene Antibodies for IFNG
- AM01149PU-N
- AM03102PU-N
- AM05867FC-N
- AM05867PU-N
- AM05867RP-N
- AM05872PU-N
- AM05875PU-N
- AM06079PU-N
- AM09167PU-N
- AM09168PU-N
- AM09169PU-N
- AM20853PU-N
- AM26302PU-L
- AM26302PU-N
- AM26303PU-L
- AM26303PU-N
- AM26712AC-N
- AM26712BT-N
- AM26712FC-N
- AM26712PU-N
- AM26712RP-N
- AM26713LE-N
- AM26713PU-N
- AM31257AF-N
- AM31257FC-N
- AM31257RP-N
- AM31307AF-N
- AM31330BT-N
- AM32189PU-N
- AM39041AC-N
- AM39041FC-N
- AM39041PU-N
- AM39041RP-N
- AP02016SU-N
- AP02016SU-S
- AP20609PU-N
- AP26389PU-N
- PM1217P
- PP1019B1
- PP1019B2
- PP1019P1
- PP1019P2
- SM1326F
- SM1701F
- SM1701P
- SM2172P
- SP2138A
- TA328343
- TA328344
- TA332378
- TA347907
- TA349348
- TA352730
- TA352731
- TA352732
- TA352733
- TA352748
- TA352749
- TA352756
- TA805797
- CF805797
- TA805798
- CF805798
- TA805799
- CF805799
- Novus Biologicals Antibodies for IFNG
-
Abcam antibodies for IFNG
-
Cloud-Clone Corp. Antibodies for IFNG
- Invitrogen Antibodies for IFNG
- antibodies-online: Search results for 1372 available IFNG Antibodies ranked by validation data
- Compare Top IFNG Antibodies
-
Recommended
- 1 ICS Antibody (anti-human)
- 1 ICC Antibody (anti-human)
- 1 Func Antibody (anti-human)
- 1 ELISPOT (Detection) Antibody (anti-human)
- 1 ELISPOT (Capture) Antibody (anti-human)
- 4 EIA Antibodies (anti-human)
- 10 RIA Antibodies (anti-human)
- 10 IP Antibodies (anti-human)
- 12 IHC Antibodies (anti-human)
- 22 Neut Antibodies (anti-human)
- 23 IF (p) Antibodies (anti-human)
- 25 IF Antibodies (anti-human)
- 40 IHC (p) Antibodies (anti-human)
- 155 FACS Antibodies (anti-human)
- 347 WB Antibodies (anti-human)
- 1 Purif Antibody (anti-mouse)
- 1 IHC Antibody (anti-mouse)
- 1 IHC (fro) Antibody (anti-mouse)
- 1 ICC Antibody (anti-mouse)
- 2 IF Antibodies (anti-mouse)
- 7 Neut Antibodies (anti-mouse)
- 10 IP Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 91 WB Antibodies (anti-mouse)
- 98 FACS Antibodies (anti-mouse)
- 1 Neut Antibody (anti-rat)
- 1 ICFC Antibody (anti-rat)
- 1 IHC (fro) Antibody (anti-rat)
- 1 IF Antibody (anti-rat)
- 2 IHC Antibodies (anti-rat)
- 8 FACS Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 97 WB Antibodies (anti-rat)
- GeneTex IFNG antibody for IFNG
-
Santa Cruz Biotechnology (SCBT) Antibodies for IFNG
- Sino Biological Antibodies for IFNG
Protein Products
- R&D Systems Proteins and Enzymes for IFNG (IFN-gamma)
- Search Origene for MassSpec and Protein Over-expression Lysates for IFNG
- Origene Custom Protein Services for IFNG
- Sino Biological Cell Lysates for IFNG
- Sino Biological Recombinant Proteins for IFNG
- ProSpec Recombinant Proteins for IFNG
-
Cloud-Clone Corp. Proteins for IFNG
- GeneTex Proteins for IFNG
-
Abcam proteins for IFNG
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for IFNG
- R&D Systems Proteome Profiler Antibody Arrays, Luminex Assays, ELISpot and FluoroSpot Kits, ELISAs, and other biochemical assays for IFNG (IFN-gamma)
- antibodies-online: Search results for 441 available IFNG Elisa Kits ranked by validation data
- Compare Top IFNG Elisa Kits
-
Recommended
- ABIN2690558
- ABIN2690559
- 3 Wild boar (Sus scrofa) ELISA Kits
- 1 Sigmodon hispidus (Hispid cotton rat) ELISA Kit
- 6 Sheep (Ovine) ELISA Kits
- 4 Rhesus Monkey ELISA Kits
- 54 Rat (Rattus) ELISA Kits
- 16 Rabbit ELISA Kits
- 21 Pig (Porcine) ELISA Kits
- 1 Non-Human Primate ELISA Kit
- 70 Mouse (Murine) ELISA Kits
- 10 Monkey ELISA Kits
- 176 Human ELISA Kits
- 10 Horse (Equine) ELISA Kits
- 4 Hamster ELISA Kits
- 12 Guinea Pig ELISA Kits
- 4 Goat ELISA Kits
- 1 Fish ELISA Kit
- 2 Duck ELISA Kits
- 15 Dog (Canine) ELISA Kits
- 16 Cow (Bovine) ELISA Kits
- 13 Chicken ELISA Kits
- 3 Cat (Feline) ELISA Kits
- 3 Camel ELISA Kits
- Sino Biological Assays for IFNG
No data available for DME Specific Peptides for IFNG Gene
Domains & Families for IFNG Gene
Gene Families for IFNG Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Disease related genes
- FDA approved drug targets
- Plasma proteins
- Predicted secreted proteins
Protein Domains for IFNG Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for IFNG Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P01579- Family:
-
- Belongs to the type II (or gamma) interferon family.
Function for IFNG Gene
Molecular function for IFNG Gene
- GENATLAS Biochemistry:
- interferon type II,gamma,19.3kDa,expressed by lymphocytes,involved in immunoregulation
- UniProtKB/Swiss-Prot Function:
- Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
LifeMap Function Summary for IFNG Gene
- Blood
Phenotypes From GWAS Catalog for IFNG Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005125 | cytokine activity | IBA | -- |
GO:0005133 | interferon-gamma receptor binding | TAS,IEA | -- |
GO:0005515 | protein binding | IPI | 7617032 |
Phenotypes for IFNG Gene
- MGI mutant phenotypes for IFNG:
-
inferred from 7 alleles
- nervous system phenotype
- normal phenotype
- homeostasis/metabolism phenotype
- respiratory system phenotype
- muscle phenotype
- cardiovascular system phenotype
- mortality/aging
- immune system phenotype
- cellular phenotype
- behavior/neurological phenotype
- growth/size/body region phenotype
- neoplasm
- digestive/alimentary phenotype
- endocrine/exocrine gland phenotype
- reproductive system phenotype
- vision/eye phenotype
- integument phenotype
- embryo phenotype
- hematopoietic system phenotype
- skeleton phenotype
- renal/urinary system phenotype
- liver/biliary system phenotype
- craniofacial phenotype
- no phenotypic analysis
- GenomeRNAi human phenotypes for IFNG:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for IFNG
-
-
ViGene Biosciences lentiviral particle packaged cDNA for IFNG gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNG gene
- Search ViGene Biosciences for IFNG
CRISPR Products
-
OriGene CRISPR knockouts for IFNG
- genomics-online: gRNA clones - Search results for 148 available IFNG gene related products
- Overview of 148 available IFNG gene related products
- Applied Biological Materials CRISPR for IFNG
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for IFNG
- GenScript: Design CRISPR guide RNA sequences for IFNG
miRNA for IFNG Gene
- miRTarBase miRNAs that target IFNG
-
- hsa-mir-16-5p (MIRT006912)
- hsa-mir-15a-5p (MIRT006913)
- hsa-mir-15b-5p (MIRT006914)
- hsa-mir-29b-3p (MIRT007034)
- hsa-mir-409-3p (MIRT007285)
- hsa-mir-26b-5p (MIRT029122)
- hsa-mir-125a-5p (MIRT437825)
- hsa-mir-27a-3p (MIRT437945)
- hsa-mir-181a-5p (MIRT437969)
- hsa-mir-24-3p (MIRT437970)
- ssc-mir-27b-3p (MIRT734368)
miRNA Products
- Search ViGene Biosciences for IFNG
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for IFNG
- Browse OriGene Inhibitory RNA Products For IFNG
- genomics-online: shRNA clones - Search results for 148 available IFNG gene related products
- Overview of 148 available IFNG gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNG gene
Clone Products
- Sino Biological Human cDNA Clone for IFNG
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IFNG
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IFNG
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for IFNG
- Applied Biological Materials Clones for IFNG
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for IFNG
-
ViGene Biosciences adenoviral particle packaged cDNA for IFNG gene
-
ViGene Biosciences lentiviral particle packaged cDNA for IFNG gene
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNG gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for IFNG Gene
Localization for IFNG Gene
Subcellular locations from UniProtKB/Swiss-Prot for IFNG Gene
- Secreted.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | TAS,IDA | -- |
GO:0005615 | extracellular space | IBA | -- |
GO:0005622 | intracellular | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for IFNG Gene
Pathways & Interactions for IFNG Gene
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Allograft rejection | ||
2 | Influenza A |
.34
.34
|
|
3 | Th17 cell differentiation | ||
4 | Interferon gamma signaling | ||
5 | Folate Metabolism |
Pathways by source for IFNG Gene
2 GeneTex pathways for IFNG Gene
1 Cell Signaling Technology pathway for IFNG Gene
31 BioSystems pathways for IFNG Gene
5 Reactome pathways for IFNG Gene
33 KEGG pathways for IFNG Gene
10 GeneGo (Thomson Reuters) pathways for IFNG Gene
7 R&D Systems pathways for IFNG Gene
12 Qiagen pathways for IFNG Gene
Interacting Proteins for IFNG Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000060 | protein import into nucleus, translocation | IDA | 15604419 |
GO:0000122 | negative regulation of transcription by RNA polymerase II | ISS | -- |
GO:0001934 | positive regulation of protein phosphorylation | IDA | 22504299 |
GO:0002250 | adaptive immune response | IBA | -- |
GO:0006915 | apoptotic process | IGI | 7828849 |
Drugs & Compounds for IFNG Gene
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Olsalazine | Approved | Pharma | Target | 1 | ||
Apremilast | Approved, Investigational | Pharma | Target | 81 | ||
Glucosamine | Approved, Investigational | Nutra | Target | 211 | ||
Simvastatin | Approved | Pharma | Competitive, Inhibitor | HMG-CoA reductase inhibitor | 537 | |
Fontolizumab | Investigational | Pharma | Target, antibody | 0 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
---|
Transcripts for IFNG Gene
mRNA/cDNA for IFNG Gene
- (1) REFSEQ mRNAs :
- (20) Additional mRNA sequences :
- (40) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for IFNG
- genomics-online: gRNA clones - Search results for 148 available IFNG gene related products
- Overview of 148 available IFNG gene related products
- Applied Biological Materials CRISPR for IFNG
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for IFNG
- GenScript: Design CRISPR guide RNA sequences for IFNG
miRNA Products
- Search ViGene Biosciences for IFNG
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for IFNG
- Browse OriGene Inhibitory RNA Products For IFNG
- genomics-online: shRNA clones - Search results for 148 available IFNG gene related products
- Overview of 148 available IFNG gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for IFNG gene
Clone Products
- Sino Biological Human cDNA Clone for IFNG
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for IFNG
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IFNG
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for IFNG
- Applied Biological Materials Clones for IFNG
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for IFNG Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for IFNG Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for IFNG Gene
NURSA nuclear receptor signaling pathways regulating expression of IFNG Gene:
IFNGSOURCE GeneReport for Unigene cluster for IFNG Gene:
Hs.856mRNA Expression by UniProt/SwissProt for IFNG Gene:
P01579-IFNG_HUMANEvidence on tissue expression from TISSUES for IFNG Gene
- Blood(4.8)
- Lymph node(3.2)
- Spleen(3.1)
- Intestine(2.8)
- Lung(2.8)
- Skin(2.8)
- Bone marrow(2.7)
- Liver(2.7)
- Nervous system(2.7)
- Heart(2.6)
- Kidney(2.4)
- Pancreas(2.2)
- Eye(2.1)
- Muscle(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for IFNG Gene
- ectoderm
- endoderm
- mesoderm
- cardiovascular
- immune
- integumentary
- lymphatic
- respiratory
- lung
- blood
- bone marrow
- hair
- red blood cell
- skin
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for IFNG
-
OriGene qPCR primer pairs and template standards for IFNG
Orthologs for IFNG Gene
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | IFNG 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | IFNG 33 |
|
||
IFN-GAMMA 34 |
|
OneToOne | |||
cow (Bos Taurus) |
Mammalia | IFNG 33 34 |
|
||
mouse (Mus musculus) |
Mammalia | Ifng 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Ifng 33 |
|
||
platypus (Ornithorhynchus anatinus) |
Mammalia | IFNG 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | IFN-GAMMA 34 |
|
OneToOne |
- Species where no ortholog for IFNG was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for IFNG Gene
No data available for Paralogs for IFNG Gene
Variants for IFNG Gene
SNP ID | Clin | Chr 12 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs137854903 | not-provided, uncertain-significance, not provided, Aplastic anemia | 68,155,253(-) | TTGATTGAT/TTGAT | 3_prime_UTR_variant | |
rs181407537 | uncertain-significance, Aplastic anemia | 68,159,620(-) | T/C | 5_prime_UTR_variant | |
rs200610212 | uncertain-significance, Aplastic anemia | 68,159,491(-) | G/A/T | intron_variant | |
rs2069707 | drug-response, Hepatitis C virus infection, response to therapy of | 68,160,508(-) | G/C | upstream_transcript_variant | |
rs2069722 | likely-benign, Aplastic anemia | 68,155,173(-) | G/A/T | 3_prime_UTR_variant |
Additional Variant Information for IFNG Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for IFNG Gene
Disorders for IFNG Gene

(247) MalaCards diseases for IFNG Gene - From: HGMD, OMIM, GTR, Orphanet, DISEASES, Novoseek, and GeneCards
Disorder | Aliases | PubMed IDs |
---|---|---|
tuberous sclerosis 2 |
|
|
hepatitis c virus |
|
|
aplastic anemia |
|
|
human immunodeficiency virus type 1 |
|
|
cutaneous leishmaniasis |
|
UniProtKB/Swiss-Prot
IFNG_HUMAN- Aplastic anemia (AA) [MIM:609135]: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements. It is characterized by peripheral pancytopenia and marrow hypoplasia. {ECO:0000269 PubMed:15327519}. Note=Disease susceptibility may be associated with variations affecting the gene represented in this entry.
Additional Disease Information for IFNG
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for IFNG Gene
Publications for IFNG Gene
- Gene-gene and gene - clinical factors interaction in acute myocardial infarction: a new detailed risk chart. (PMID: 20388088) Licastro F … Ferrari R (Current pharmaceutical design 2010) 3 22 44 58
- Cytokine gene polymorphisms and BALF cytokine levels in interstitial lung diseases. (PMID: 19117745) Vasakova M … Striz I (Respiratory medicine 2009) 3 22 44 58
- Cytokine gene polymorphisms across tuberculosis clinical spectrum in Pakistani patients. (PMID: 19274101) Ansari A … Hussain R (PloS one 2009) 3 22 44 58
- Effect of desensitization in solid organ transplant recipients depends on some cytokines genes polymorphism. (PMID: 19332120) Lobashevsky AL … Turrentine MW (Transplant immunology 2009) 3 22 44 58
- Genetic variants in immunoregulatory genes and risk for childhood lymphomas. (PMID: 19508433) Andrie E … Petridou ET (European journal of haematology 2009) 3 22 44 58
Products for IFNG Gene
- R&D Systems Antibodies for IFNG (IFN-gamma)
- R&D Systems Proteins and Enzymes for IFNG (IFN-gamma)
- R&D Systems ELISAs, ELISpot and FluoroSpot Kits, Luminex Assays, Proteome Profiler Antibody Arrays, and other biochemical assays for IFNG (IFN-gamma)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for IFNG
- AM01149PU-N
- AM03102PU-N
- AM05867FC-N
- AM05867PU-N
- AM05867RP-N
- AM05872PU-N
- AM05875PU-N
- AM06079PU-N
- AM09167PU-N
- AM09168PU-N
- AM09169PU-N
- AM20853PU-N
- AM26302PU-L
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- AM26303PU-L
- AM26303PU-N
- AM26712AC-N
- AM26712BT-N
- AM26712FC-N
- AM26712PU-N
- AM26712RP-N
- AM26713LE-N
- AM26713PU-N
- AM31257AF-N
- AM31257FC-N
- AM31257RP-N
- AM31307AF-N
- AM31330BT-N
- AM32189PU-N
- AM39041AC-N
- AM39041FC-N
- AM39041PU-N
- AM39041RP-N
- AP02016SU-N
- AP02016SU-S
- AP20609PU-N
- AP26389PU-N
- PM1217P
- PP1019B1
- PP1019B2
- PP1019P1
- PP1019P2
- SM1326F
- SM1701F
- SM1701P
- SM2172P
- SP2138A
- TA328343
- TA328344
- TA332378
- TA347907
- TA349348
- TA352730
- TA352731
- TA352732
- TA352733
- TA352748
- TA352749
- TA352756
- TA805797
- CF805797
- TA805798
- CF805798
- TA805799
- CF805799
- Custom Assay ServicesOriGene ELISA Kits for IFNG
- Search Origene for MassSpec and Protein Over-expression Lysates for IFNG
- Origene Custom Protein Services for IFNG
- Origene shrna, sirna, and RNAi products in human, mouse, rat for IFNG
- Browse OriGene Inhibitory RNA Products For IFNG
- OriGene qPCR primer pairs and template standards for IFNG
- OriGene qPCR primer pairs for IFNG
- OriGene CRISPR knockouts for IFNG
- OriGene ORF clones in human for IFNG
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For IFNG
- GenScript: Next-day shipping of latest version cDNA ORF clones for IFNG in any vector
- GenScript Custom Purified and Recombinant Proteins Services for IFNG
- GenScript Custom Assay Services for IFNG
- GenScript Custom overexpressing Cell Line Services for IFNG
- GenScript: Design CRISPR guide RNA sequences for IFNG
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for IFNG
- Cell Signaling Technology (CST) Antibodies for IFNG (IFNG)
- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for IFNG
- Sino Biological Cell Lysates for IFNG
- Sino Biological Recombinant Proteins for IFNG
- Sino Biological Antibodies for IFNG
- Sino Biological Assays for IFNG
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for IFNG
- Novus Biologicals proteins and lysates for IFNG
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for IFNG
- Abcam proteins for IFNG
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for IFNG
- Cloud-Clone Corp. Antibodies for IFNG
- Cloud-Clone Corp. Proteins for IFNG
- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for IFNG
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for IFNG
- VectorBuilder custom plasmid, inducible vectors for IFNG
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for IFNG
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for IFNG
- antibodies-online: Search results for 1372 available IFNG Antibodies ranked by validation data
- Compare Top IFNG Antibodies
- Recommended
- 97 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 8 FACS Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
- 1 IF Antibody (anti-rat)
- 1 IHC (fro) Antibody (anti-rat)
- 1 ICFC Antibody (anti-rat)
- 1 Neut Antibody (anti-rat)
- 98 FACS Antibodies (anti-mouse)
- 91 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 10 IP Antibodies (anti-mouse)
- 7 Neut Antibodies (anti-mouse)
- 2 IF Antibodies (anti-mouse)
- 1 ICC Antibody (anti-mouse)
- 1 IHC (fro) Antibody (anti-mouse)
- 1 IHC Antibody (anti-mouse)
- 1 Purif Antibody (anti-mouse)
- 347 WB Antibodies (anti-human)
- 155 FACS Antibodies (anti-human)
- 40 IHC (p) Antibodies (anti-human)
- 25 IF Antibodies (anti-human)
- 23 IF (p) Antibodies (anti-human)
- 22 Neut Antibodies (anti-human)
- 12 IHC Antibodies (anti-human)
- 10 IP Antibodies (anti-human)
- 10 RIA Antibodies (anti-human)
- 4 EIA Antibodies (anti-human)
- 1 ELISPOT (Capture) Antibody (anti-human)
- 1 ELISPOT (Detection) Antibody (anti-human)
- 1 Func Antibody (anti-human)
- 1 ICC Antibody (anti-human)
- 1 ICS Antibody (anti-human)
- antibodies-online: Search results for 441 available IFNG Elisa Kits ranked by validation data
- Compare Top IFNG Elisa Kits
- Recommended
- 3 Camel ELISA Kits
- 3 Cat (Feline) ELISA Kits
- 13 Chicken ELISA Kits
- 16 Cow (Bovine) ELISA Kits
- 15 Dog (Canine) ELISA Kits
- 2 Duck ELISA Kits
- 1 Fish ELISA Kit
- 4 Goat ELISA Kits
- 12 Guinea Pig ELISA Kits
- 4 Hamster ELISA Kits
- 10 Horse (Equine) ELISA Kits
- 176 Human ELISA Kits
- 10 Monkey ELISA Kits
- 70 Mouse (Murine) ELISA Kits
- 1 Non-Human Primate ELISA Kit
- 21 Pig (Porcine) ELISA Kits
- 16 Rabbit ELISA Kits
- 54 Rat (Rattus) ELISA Kits
- 4 Rhesus Monkey ELISA Kits
- 6 Sheep (Ovine) ELISA Kits
- 1 Sigmodon hispidus (Hispid cotton rat) ELISA Kit
- 3 Wild boar (Sus scrofa) ELISA Kits
- ABIN2690559
- ABIN2690558
- antibodies-online: Search results for 255 available IFNG Proteins ranked by validation data
- Compare Top IFNG Proteins
- GeneTex IFNG antibody for IFNG
- GeneTex Proteins for IFNG
- ViGene Biosciences adenoviral particle packaged cDNA for IFNG gene
- ViGene Biosciences lentiviral particle packaged cDNA for IFNG gene
- ViGene Biosciences ready-to-package AAV shRNAs for IFNG gene
- Search ViGene Biosciences for IFNG
- Santa Cruz Biotechnology (SCBT) Antibodies for IFNG
- Search Santa Cruz Biotechnology (SCBT) for IFNG siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for IFNG
- Horizon Cell Lines for IFNG
- genomics-online: cdna clones - Search results for 148 available IFNG gene related products
- Overview of 148 available IFNG gene related products
- orf clones - Search results for 148 available IFNG gene related products
- Overview of 148 available IFNG gene related products
- genomics-online: gRNA clones - Search results for 148 available IFNG gene related products
- Overview of 148 available IFNG gene related products
- genomics-online: primer clones - Search results for 148 available IFNG gene related products
- Overview of 148 available IFNG gene related products
- genomics-online: shRNA clones - Search results for 148 available IFNG gene related products
- Overview of 148 available IFNG gene related products
Sources for IFNG Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
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- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
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- (114) diseasecard
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- (133) ENCODE
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- (135) Horizon
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- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew