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IFNA6 Gene

protein-coding   GIFtS: 54
GCID: GC09M021340

Interferon, Alpha 6

  See IFNA6-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Interferon, Alpha 61 2     IFN-alpha-62 3
Interferon Alpha-542 3     IFN-alphaK2
Interferon Alpha-K2 3     Interferon Alpha-62
LeIF K2 3     

External Ids:    HGNC: 54271   Entrez Gene: 34432   Ensembl: ENSG000001202357   OMIM: 1475665   UniProtKB: P050133   

Export aliases for IFNA6 gene to outside databases

Previous GC identifers: GC09M021677 GC09M021551


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IFNA6 Gene:
IFNA6 (interferon, alpha 6) is a protein-coding gene. Diseases associated with IFNA6 include hiv-1. GO annotations related to this gene include cytokine receptor binding and cytokine activity. An important paralog of this gene is IFNA7.

UniProtKB/Swiss-Prot: IFNA6_HUMAN, P05013
Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of
two enzymes: a protein kinase and an oligoadenylate synthetase

Gene Wiki entry for IFNA6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NC_018920.2  NT_008413.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the IFNA6 gene promoter:
         HEN1   Egr-3   Egr-2   IRF-7A   NF-kappaB1   NF-kappaB   Egr-4   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for IFNA6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IFNA6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p22   Ensembl cytogenetic band:  9p21.3   HGNC cytogenetic band: 9p22

IFNA6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFNA6 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M021340:  view genomic region     (about GC identifiers)

Start:
21,349,834 bp from pter      End:
21,351,377 bp from pter
Size:
1,544 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: IFNA6_HUMAN, P05013 (See protein sequence)
Recommended Name: Interferon alpha-6 precursor  
Size: 189 amino acids; 22141 Da
Secondary accessions: Q5VYQ1

Explore the universe of human proteins at neXtProt for IFNA6: NX_P05013

Explore proteomics data for IFNA6 at MOPED


See IFNA6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_066282.1  
ENSEMBL proteins: 
 ENSP00000369558  
Reactome Protein details: P05013

IFNA6 Human Recombinant Protein Products:

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Novus Biologicals IFNA6 Protein
Novus Biologicals IFNA6 Lysates
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Browse ProSpec Recombinant Proteins
Browse Proteins at Cloud-Clone Corp.

 
Search eBioscience for Proteins for IFNA6 

 
antibodies-online proteins for IFNA6 (10 products) 

 
antibodies-online peptides for IFNA6

IFNA6 Antibody Products:

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ThermoFisher Antibodies for IFNA6
antibodies-online antibodies for IFNA6 (28 products) 

IFNA6 Assay Products:

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antibodies-online kits for IFNA6 (4 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
IFN: Interferons

4 InterPro protein domains:
 IPR012351 4_helix_cytokine_core
 IPR015589 Interferon_alpha
 IPR000471 Interferon_alpha/beta/delta
 IPR009079 4_helix_cytokine-like_core

Graphical View of Domain Structure for InterPro Entry P05013

ProtoNet protein and cluster: P05013

1 Blocks protein domain: IPB000471 Interferon alpha

UniProtKB/Swiss-Prot: IFNA6_HUMAN, P05013
Similarity: Belongs to the alpha/beta interferon family


Find genes that share domains with IFNA6           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: IFNA6_HUMAN, P05013
Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of
two enzymes: a protein kinase and an oligoadenylate synthetase

     Genatlas biochemistry entry for IFNA6:
interferon type I,alpha 6,leukocyte

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005125cytokine activity IBA--
GO:0005126cytokine receptor binding ----
GO:0005132type I interferon receptor binding IBA--
     
Find genes that share ontologies with IFNA6           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for IFNA6:
 Synthetic lethal with Ras 

Animal Models:
   genOway: Develop your customized and physiologically relevant rodent model for IFNA6

miRNA
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Search for qRT-PCR Assays for microRNAs that regulate IFNA6
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Inhib. RNA
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OriGene RNAi products in human, mouse, rat for IFNA6
Predesigned siRNA for gene silencing in human, mouse, rat IFNA6

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for IFNA6

Clone
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OriGene clones in human, mouse for IFNA6 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: IFNA6 (NM_021002)
Sino Biological Human cDNA Clone for IFNA6
DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFNA6
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFNA6

Cell Line
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GenScript Custom overexpressing Cell Line Services for IFNA6
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNA6


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
IFNA6_HUMAN, P05013: Secreted
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular5

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005575cellular_component ND--
GO:0005576extracellular region TAS--
GO:0005615extracellular space IBA--

Find genes that share ontologies with IFNA6           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for IFNA6 About   (see all 21)  
See pathways by source

SuperPathContained pathways About
1Toll-like receptor signaling pathway
Toll-like receptor signaling pathway0.94
Regulation of toll-like receptor signaling pathway0.93
Toll-like receptor signaling pathway0.94
Hepatitis B0.31
2Immune response IFN alpha beta signaling pathway
Immune response IFN alpha beta signaling pathway0.69
Interferon alpha/beta signaling0.43
Regulation of IFNA signaling0.69
3RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways0.47
TRAF6 mediated IRF7 activation0.40
RIG-I-like receptor signaling pathway0.47
4Influenza A
Influenza A0.34
Herpes simplex infection0.33
Measles0.34
5Interferon Signaling
Interferon Signaling0.59
Cytokine Signaling in Immune system0.59


Find genes that share SuperPaths with IFNA6           About GenesLikeMe

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

4 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for IFNA6
    Cytokine Network
Interferon Pathway
JAK-STAT Pathway
all-trans-Retinoic Acid Mediated Apoptosis

2 GeneGo (Thomson Reuters) Pathways for IFNA6
    Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway
Immune response IFN alpha/beta signaling pathway

2 BioSystems Pathways for IFNA6
    Toll-like receptor signaling pathway
Regulation of toll-like receptor signaling pathway


4 Reactome Pathways for IFNA6
    Regulation of IFNA signaling
Interferon alpha/beta signaling
Factors involved in megakaryocyte development and platelet production
TRAF6 mediated IRF7 activation


Selected Kegg Pathways  (Kegg details for IFNA6) (see all 15):
    Cytokine-cytokine receptor interaction
Regulation of autophagy
PI3K-Akt signaling pathway
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway

    Pathway & Disease-focused RT2 Profiler PCR Array including IFNA6: 
          Interferons & Receptors in human mouse rat

Interactions:

    Search GeneGlobe Interaction Network for IFNA6

STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

26 Interacting proteins for IFNA6 (P050133 ENSP000003695584) via UniProtKB, MINT, STRING, and/or I2D (see top 5)
InteractantInteraction Details
GeneCardExternal ID(s)
GKAP1Q5VSY03I2D: score=1 
KLHL12Q53G593I2D: score=1 
MAGEA11P433643I2D: score=1 
PLSCR1O151623I2D: score=1 
IFNA14ENSP000003695714STRING: ENSP00000369571
IFNA16ENSP000003695644STRING: ENSP00000369564
IFNA2ENSP000003695544STRING: ENSP00000369554
IFNA8ENSP000003695534STRING: ENSP00000369553
IFNAR1ENSP000002701394STRING: ENSP00000270139
IFNAR2ENSP000003439574STRING: ENSP00000343957
IFNB1ENSP000003695814STRING: ENSP00000369581
IFNGENSP000002291354STRING: ENSP00000229135
IRF1ENSP000002454144STRING: ENSP00000245414
IRF2ENSP000003772184STRING: ENSP00000377218
IRF9ENSP000003800734STRING: ENSP00000380073
STAT2ENSP000003157684STRING: ENSP00000315768
JAK1ENSP000003432044STRING: ENSP00000343204
PTPN1ENSP000003606834STRING: ENSP00000360683
PTPN11ENSP000003409444STRING: ENSP00000340944
PTPN6ENSP000003915924STRING: ENSP00000391592
SOCS1ENSP000003294184STRING: ENSP00000329418
SOCS3ENSP000003303414STRING: ENSP00000330341
TYK2ENSP000002648184STRING: ENSP00000264818
IFNGR1ENSP000003567134STRING: ENSP00000356713
IFNGR2ENSP000002902194STRING: ENSP00000290219
--ENSP000003695604STRING: ENSP00000369560
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Gene Ontology (GO): Selected biological process terms (see all 17):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0002250adaptive immune response IBA--
GO:0002286T cell activation involved in immune response IBA--
GO:0002323natural killer cell activation involved in immune response IBA--
GO:0006952defense response ----
GO:0006959humoral immune response IBA--

Find genes that share ontologies with IFNA6           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for IFNA6



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for IFNA6 gene: 
NM_021002.2  

Unigene Cluster for IFNA6:

Interferon, alpha 6
Hs.533470
Unigene Representative Sequence: BC069471
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000380210(uc011lni.2)
miRNA
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Search for qRT-PCR Assays for microRNAs that regulate IFNA6
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for IFNA6
Predesigned siRNA for gene silencing in human, mouse, rat IFNA6
Clone
Products:
     
OriGene clones in human, mouse for IFNA6 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: IFNA6 (NM_021002)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFNA6
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFNA6
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for IFNA6
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat IFNA6
  QuantiTect SYBR Green Assays in human, mouse, rat IFNA6
  QuantiFast Probe-based Assays in human, mouse, rat IFNA6

Additional mRNA sequence: 

BC069471.1 BC096697.1 BC096710.1 BC096730.1 BC098357.1 

1 DOTS entry:

DT.91811057 

6 AceView cDNA sequences:

BC074956 NM_002172 V00542 BC069471 NM_021002 CR541921 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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IFNA6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AGATCCTTCT
IFNA6 Expression
About this image

IFNA6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

IFNA6 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.533470
    Pathway & Disease-focused RT2 Profiler PCR Array including IFNA6: 
          Interferons & Receptors in human mouse rat

Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for IFNA6
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat IFNA6
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QuantiFast Probe-based Assays in human, mouse, rat IFNA6
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNA6

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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ENSEMBL Gene Tree for IFNA6 (if available)
TreeFam Gene Tree for IFNA6 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for IFNA6 gene
IFNA72  IFNA22  IFNA42  IFNE2  IFNA142  IFNA52  IFNK2  IFNA12  
IFNA212  IFNA172  IFNB12  IFNA132  IFNW12  IFNA162  IFNA102  IFNA82  
18 SIMAP similar genes for IFNA6 using alignment to 1 protein entry:     IFNA6_HUMAN:
IFNA14    IFNA5    IFN-2    IFNA    IFNA10    IFNA4
IFNA17    IFNA21    IFNA2    IFNA1    IFNA13    IFNA2B
IFNA7    IFNA16    IFNA8    IFNW1    IFNE    IFNB1

Find genes that share paralogs with IFNA6           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for IFNA6 (see all 104)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 9 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1838622571,2
--21349841(+) AACTTC/GAGTAT 1 -- ds50010--------
rs1893663451,2
--21349900(+) GAGAAC/TCGGCT 1 -- ds50010--------
rs283837791,2
C,F--21349986(-) TAGTCG/TATGTA 1 -- ds5001 ese31Minor allele frequency- T:0.03NA 120
rs1925346121,2
--21349987(+) ACATCA/GACTAA 1 -- ds50010--------
rs1843841961,2
--21350017(+) TTATGG/TTATCA 1 -- ds50010--------
rs29901421,2
C,H--21350049(+) TATGCA/TTTTAT 1 -- ds5001 ese39Minor allele frequency- T:0.00NA WA CSA EA 369
rs29901431,2
C,F,A--21350050(+) ATGCTT/CTTATA 1 -- ds5001 ese33Minor allele frequency- C:0.28WA NA EA 358
rs29901441,2
C,F,A--21350078(+) ATTATA/TGTCAA 1 -- ds50016Minor allele frequency- T:0.23WA CSA NA EA 366
rs169383521,2
C,F--21350168(+) CACGAT/CGTTGC 1 -- ds5001 ese35Minor allele frequency- C:0.05NA CSA WA 262
rs123757901,2
C,H--21350174(+) GTTGCT/CTAACA 1 -- ds50014Minor allele frequency- C:0.00NS EA 420

HapMap Linkage Disequilibrium report for IFNA6 (21349834 - 21351377 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for IFNA6:    About this table    
Variant IDTypeSubtypePubMed ID
nsv892724CNV Gain21882294
nsv892736CNV Gain21882294

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing IFNA6
DNA2.0 Custom Variant and Variant Library Synthesis for IFNA6

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 147566    OMIM disorders: --

1 disease for IFNA6:    
About MalaCards
hiv-1


Find genes that share disorders with IFNA6           About GenesLikeMe

Genetic Association Database (GAD): IFNA6
Human Genome Epidemiology (HuGE) Navigator: IFNA6 (7 documents)

Export disorders for IFNA6 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for IFNA6 gene, integrated from 10 sources (see all 63):
(articles sorted by number of sources associating them with IFNA6)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Dengue hemorrhagic fever is associated with polymorphisms in JAK1. (PubMed id 20588308)1, 4 Silva L.K....Teixeira M.G. (Eur. J. Hum. Genet. 2010)
  2. Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)1, 4 Schuurhof A....Janssen R. (Pediatr. Pulmonol. 2010)
  3. Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. (PubMed id 20331378)1, 4 Mosbruger T.L....Thio C.L. (J. Infect. Dis. 2010)
  4. Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations. (PubMed id 20574843)1, 4 Yang X.R....Goldstein A.M. (Fam. Cancer 2010)
  5. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)1, 4 Siezen C.L....Janssen R. (Pediatr. Infect. Dis. J. 2009)
  6. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)1, 4 Janssen R....Hoebee B. (J. Infect. Dis. 2007)
  7. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (Protein Sci. 2004)
  8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  9. Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia. (PubMed id 1385305)1, 3 Olopade O.I....Diaz M.O. (Genomics 1992)
  10. Structural relationship of human interferon alpha genes and pseudogenes. (PubMed id 4057246)1, 2 Henco K.... Weissmann C. (J. Mol. Biol. 1985)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 3443 HGNC: 5427 AceView: IFNA14 Ensembl:ENSG00000120235 euGenes: HUgn3443
ECgene: IFNA6 Kegg: 3443 H-InvDB: IFNA6

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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PharmGKB entry for IFNA6 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for IFNA6 gene:
Search GeneIP for patents involving IFNA6

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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 EMD Millipore genomic analysis products

  
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