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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IFNA6 Gene

protein-coding   GIFtS: 56
GCID: GC09M021340

Interferon, Alpha 6

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Interferon, Alpha 61 2     IFN-alpha-62 3
Interferon Alpha-542 3     IFN-alphaK2
Interferon Alpha-K2 3     Interferon Alpha-62
LeIF K2 3     

External Ids:    HGNC: 54271   Entrez Gene: 34432   Ensembl: ENSG000001202357   OMIM: 1475665   UniProtKB: P050133   

Export aliases for IFNA6 gene to outside databases

Previous GC identifers: GC09M021677 GC09M021551


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for IFNA6 Gene: 
IFNA6 (interferon, alpha 6) is a protein-coding gene. Diseases associated with IFNA6 include dengue hemorrhagic fever, and hemorrhagic fever, and among its related super-pathways are Toll-like receptor signaling pathway and Immune response IFN alpha/beta signaling pathway. GO annotations related to this gene include cytokine receptor binding and cytokine activity. An important paralog of this gene is IFNA7.

UniProtKB/Swiss-Prot: IFNA6_HUMAN, P05013
Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of
two enzymes: a protein kinase and an oligoadenylate synthetase

Gene Wiki entry for IFNA6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.2  NT_008413.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IFNA6 gene promoter:
         HEN1   Egr-3   Egr-2   IRF-7A   NF-kappaB1   NF-kappaB   Egr-4   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for IFNA6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IFNA6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p22   Ensembl cytogenetic band:  9p21.3   HGNC cytogenetic band: 9p22

IFNA6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFNA6 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M021340:  view genomic region     (about GC identifiers)

Start:
21,349,834 bp from pter      End:
21,351,377 bp from pter
Size:
1,544 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: IFNA6_HUMAN, P05013 (See protein sequence)
Recommended Name: Interferon alpha-6 precursor  
Size: 189 amino acids; 22141 Da
Subcellular location: Secreted
Secondary accessions: Q5VYQ1

Explore the universe of human proteins at neXtProt for IFNA6: NX_P05013

Explore proteomics data for IFNA6 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P05013

  • IFNA6 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    IFNA6 Protein Expression
    REFSEQ proteins: NP_066282.1  
    ENSEMBL proteins: 
     ENSP00000369558  
    Reactome Protein details: P05013
    Human Recombinant Protein Products for IFNA6: 
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    Novus Biologicals IFNA6 Protein
    Novus Biologicals IFNA6 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005576extracellular region TAS--
    GO:0005615extracellular space IEA--

    IFNA6 for ontologies           About GeneDecksing



    IFNA6 Antibody Products: 
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    Browse ELISAs at Cloud-Clone Corp. 
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    IFN: Interferons

    4 InterPro protein domains:
     IPR012351 4_helix_cytokine_core
     IPR015589 Interferon_alpha
     IPR000471 Interferon_alpha/beta/delta
     IPR009079 4_helix_cytokine-like_core

    Graphical View of Domain Structure for InterPro Entry P05013

    ProtoNet protein and cluster: P05013

    1 Blocks protein domain: IPB000471 Interferon alpha

    UniProtKB/Swiss-Prot: IFNA6_HUMAN, P05013
    Similarity: Belongs to the alpha/beta interferon family


    IFNA6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IFNA6_HUMAN, P05013
    Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of
    two enzymes: a protein kinase and an oligoadenylate synthetase

         Genatlas biochemistry entry for IFNA6:
    interferon type I,alpha 6,leukocyte

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005125cytokine activity IEA--
    GO:0005126cytokine receptor binding NAS--
         
    IFNA6 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for IFNA6:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for IFNA6 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for IFNA6

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IFNA6 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IFNA6 

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    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFNA6
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNA6


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for IFNA6 About   (see all 23)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Toll-like receptor signaling pathway
    Toll-like receptor signaling pathway0.93
    Hepatitis B0.31
    Toll-like receptor signaling pathway0.93
    2Immune response IFN alpha/beta signaling pathway
    Immune response IFN alpha/beta signaling pathway0.71
    Interferon alpha/beta signaling0.45
    Regulation of IFNA signaling0.71
    3Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway
    Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway0.91
    Immune response Role of TLRs 3 and 4 in cell antiviral response: TICAM1-specific signaling pathways0.91
    4RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
    RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways0.52
    RIG-I-like receptor signaling pathway0.52
    5Influenza A
    Influenza A0.34
    Herpes simplex infection0.33
    Measles0.34

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show some pathways

    2 EMD Millipore Pathways for IFNA6
        Immune response IFN alpha/beta signaling pathway
    Immune response Role of TLRs 3 and 4 in cell antiviral response- TICAM1-specific signaling pathways

    4 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for IFNA6
        Cytokine Network
    Interferon Pathway
    JAK-STAT Pathway
    all-trans-Retinoic Acid Mediated Apoptosis

    2 GeneGo (Thomson Reuters) Pathways for IFNA6
        Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway
    Immune response IFN alpha/beta signaling pathway

    1 BioSystems Pathway for IFNA6
        Toll-like receptor signaling pathway

    10/10        Reactome Pathways for IFNA6 (see first 5)
        Hemostasis
    Regulation of IFNA signaling
    Interferon alpha/beta signaling
    Cytokine Signaling in Immune system
    RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
    TRAF6 mediated IRF7 activation
    Factors involved in megakaryocyte development and platelet production
    Interferon Signaling
    Innate Immune System
    Immune System


    15/15         Kegg Pathways  (Kegg details for IFNA6) (see first 5):
        Cytokine-cytokine receptor interaction
    Regulation of autophagy
    PI3K-Akt signaling pathway
    Toll-like receptor signaling pathway
    RIG-I-like receptor signaling pathway
    Cytosolic DNA-sensing pathway
    Jak-STAT signaling pathway
    Natural killer cell mediated cytotoxicity
    Tuberculosis
    Hepatitis C
    Hepatitis B
    Measles
    Influenza A
    Herpes simplex infection
    Autoimmune thyroid disease


    IFNA6 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for IFNA6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

    5/26 Interacting proteins for IFNA6 (P050133 ENSP000003695584) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GKAP1Q5VSY03I2D: score=1 
    KLHL12Q53G593I2D: score=1 
    MAGEA11P433643I2D: score=1 
    PLSCR1O151623I2D: score=1 
    IFNA14ENSP000003695714STRING: ENSP00000369571
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006952defense response ----
    GO:0007596blood coagulation TAS--
    GO:0009615response to virus NAS--
    GO:0019221cytokine-mediated signaling pathway TAS--
    GO:0045087innate immune response TAS--

    IFNA6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IFNA6

    Search CenterWatch for drugs/clinical trials and news about IFNA6

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for IFNA6 gene: 
    NM_021002.2  

    Unigene Cluster for IFNA6:

    Interferon, alpha 6
    Hs.533470
    Unigene Representative Sequence: BC069471
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000380210(uc011lni.2)
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate IFNA6
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    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for IFNA6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IFNA6
    Clone
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    OriGene clones in human, mouse for IFNA6 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IFNA6 (NM_021002)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFNA6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFNA6
    Sirion Biotech Customized lentivirus for stable overexpression of IFNA6 
                         Customized lentivirus expression plasmids for stable overexpression of IFNA6 
    Primer
    Products:
        
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    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat IFNA6
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IFNA6
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IFNA6

    Additional mRNA sequence: 

    BC069471.1 BC096697.1 BC096710.1 BC096730.1 BC098357.1 

    1 DOTS entry:

    DT.91811057 

    6 AceView cDNA sequences:

    BC074956 NM_002172 V00542 BC069471 CR541921 NM_021002 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IFNA6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGATCCTTCT
    IFNA6 Expression
    About this image


    See IFNA6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IFNA6

    SOURCE GeneReport for Unigene cluster: Hs.533470
        SABiosciences Expression via Pathway-Focused PCR Array including IFNA6: 
              Interferons & Receptors in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNA6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for IFNA6 (if available)
    TreeFam Gene Tree for IFNA6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IFNA6 gene
    IFNA72  IFNA22  IFNA42  IFNE2  IFNA142  IFNA52  IFNK2  IFNA12  
    IFNA212  IFNA172  IFNB12  IFNA132  IFNW12  IFNA162  IFNA102  IFNA82  
    18 SIMAP similar genes for IFNA6 using alignment to 1 protein entry:     IFNA6_HUMAN:
    IFNA14    IFNA5    IFN-2    IFNA    IFNA10    IFNA4
    IFNA17    IFNA21    IFNA2    IFNA1    IFNA13    IFNA2B
    IFNA7    IFNA16    IFNA8    IFNW1    IFNE    IFNB1

    IFNA6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/104 SNPs in IFNA6 are shown (see all 104)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1838622571,2
    --21349841(+) AACTTC/GAGTAT 1 -- ds50010--------
    rs1893663451,2
    --21349900(+) GAGAAC/TCGGCT 1 -- ds50010--------
    rs283837791,2
    C,F--21349986(-) TAGTCG/TATGTA 1 -- ds5001 ese31Minor allele frequency- T:0.03NA 120
    rs1925346121,2
    --21349987(+) ACATCA/GACTAA 1 -- ds50010--------
    rs1843841961,2
    --21350017(+) TTATGG/TTATCA 1 -- ds50010--------
    rs29901421,2
    C,H--21350049(+) TATGCA/TTTTAT 1 -- ds5001 ese39Minor allele frequency- T:0.00NA WA CSA EA 369
    rs29901431,2
    C,F,A--21350050(+) ATGCTT/CTTATA 1 -- ds5001 ese33Minor allele frequency- C:0.28WA NA EA 358
    rs29901441,2
    C,F,A--21350078(+) ATTATA/TGTCAA 1 -- ds50016Minor allele frequency- T:0.23WA CSA NA EA 366
    rs169383521,2
    C,F--21350168(+) CACGAT/CGTTGC 1 -- ds5001 ese35Minor allele frequency- C:0.05NA CSA WA 262
    rs123757901,2
    C,H--21350174(+) GTTGCT/CTAACA 1 -- ds50014Minor allele frequency- C:0.00NS EA 420

    HapMap Linkage Disequilibrium report for IFNA6 (21349834 - 21351377 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for IFNA6:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv892724CNV Gain21882294
    nsv892736CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for IFNA6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 147566    OMIM disorders: --

    13 diseases for IFNA6:    About MalaCards
    dengue hemorrhagic fever    hemorrhagic fever    measles    hiv/aids
    autoimmune thyroiditis    bronchiolitis    hepatitis c    influenza
    hepatitis b    hepatitis    thyroiditis    melanoma
    tuberculosis


    IFNA6 for disorders           About GeneDecksing

    Genetic Association Database (GAD): IFNA6
    Human Genome Epidemiology (HuGE) Navigator: IFNA6 (7 documents)

    Export disorders for IFNA6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IFNA6 gene, integrated from 9 sources (see all 63):
    (articles sorted by number of sources associating them with IFNA6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Dengue hemorrhagic fever is associated with polymorph isms in JAK1. (PubMed id 20588308)1, 4 Silva L.K....Teixeira M.G. (2010)
    2. Interleukin-9 polymorphism in infants with respirator y syncytial virus infection: an opposite effect in boys and girls. (PubMed id 20503287)1, 4 Schuurhof A....Janssen R. (2010)
    3. Large-scale candidate gene analysis of spontaneous cl earance of hepatitis C virus. (PubMed id 20331378)1, 4 Mosbruger T.L....Thio C.L. (2010)
    4. Associations of 9p21 variants with cutaneous malignan t melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with a nd without CDKN2A mutations. (PubMed id 20574843)1, 4 Yang X.R....Goldstein A.M. (2010)
    5. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)1, 4 Siezen C.L....Janssen R. (2009)
    6. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. (PubMed id 17703412)1, 4 Janssen R....Hoebee B. (2007)
    7. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia. (PubMed id 1385305)1, 3 Olopade O.I....Diaz M.O. (1992)
    10. Structural relationship of human interferon alpha genes and pseudogenes. (PubMed id 4057246)1, 2 Henco K.... Weissmann C. (1985)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3443 HGNC: 5427 AceView: IFNA14 Ensembl:ENSG00000120235 euGenes: HUgn3443
    ECgene: IFNA6 Kegg: 3443 H-InvDB: IFNA6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for IFNA6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for IFNA6 gene:
    Search GeneIP for patents involving IFNA6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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