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IFNA17 Gene

protein-coding   GIFtS: 53
GCID: GC09M021227

Interferon, Alpha 17

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Interferon, Alpha 171 2     IFN-alphaI2
Interferon Alpha-882 3     IFNA2
Interferon Alpha-I'2 3     INFA2
Interferon Alpha-T2 3     LEIF2C12
LeIF I2 3     Interferon Alpha-172
IFN-alpha-172 3     Interferon Alpha-WA2

External Ids:    HGNC: 54221   Entrez Gene: 34512   Ensembl: ENSG000002348297   OMIM: 1475835   UniProtKB: P015713   

Export aliases for IFNA17 gene to outside databases

Previous GC identifers: GC09M021554 GC09M021428 GC09M021217


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IFNA17 Gene:
IFNA17 (interferon, alpha 17) is a protein-coding gene. Diseases associated with IFNA17 include pulmonary sarcoidosis, and hiv/aids. GO annotations related to this gene include type I interferon receptor binding and cytokine activity. An important paralog of this gene is IFNA7.

UniProtKB/Swiss-Prot: IFN17_HUMAN, P01571
Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of
two enzymes: a protein kinase and an oligoadenylate synthetase

Gene Wiki entry for IFNA17 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NC_018920.2  NT_008413.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the IFNA17 gene promoter:
         Egr-3   Egr-2   Egr-4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIFNA17 promoter sequence
   Search Chromatin IP Primers for IFNA17

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IFNA17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p22   Ensembl cytogenetic band:  9p21.3   HGNC cytogenetic band: 9p22

IFNA17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFNA17 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M021227:  view genomic region     (about GC identifiers)

Start:
21,227,242 bp from pter      End:
21,228,221 bp from pter
Size:
980 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: IFN17_HUMAN, P01571 (See protein sequence)
Recommended Name: Interferon alpha-17 precursor  
Size: 189 amino acids; 21728 Da
Secondary accessions: Q14639 Q4KMT4 Q5VZ53 Q7M4Q4

Explore the universe of human proteins at neXtProt for IFNA17: NX_P01571

Explore proteomics data for IFNA17 at MOPED


See IFNA17 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_067091.1  
ENSEMBL proteins: 
 ENSP00000411940  
Reactome Protein details: P01571

IFNA17 Human Recombinant Protein Products:

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OriGene Protein Over-expression Lysate for IFNA17
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Novus Biologicals IFNA17 Protein
Novus Biologicals IFNA17 Lysates
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IFNA17 Assay Products:

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GenScript Custom Assay Services for IFNA17
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Browse CLIAs at Cloud-Clone Corp.


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
IFN: Interferons

4 InterPro protein domains:
 IPR012351 4_helix_cytokine_core
 IPR015589 Interferon_alpha
 IPR000471 Interferon_alpha/beta/delta
 IPR009079 4_helix_cytokine-like_core

Graphical View of Domain Structure for InterPro Entry P01571

ProtoNet protein and cluster: P01571

1 Blocks protein domain: IPB000471 Interferon alpha

UniProtKB/Swiss-Prot: IFN17_HUMAN, P01571
Similarity: Belongs to the alpha/beta interferon family


IFNA17 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: IFN17_HUMAN, P01571
Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of
two enzymes: a protein kinase and an oligoadenylate synthetase

     Genatlas biochemistry entry for IFNA17:
interferon type I,alpha 17,leukocyte

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005125cytokine activity IBA--
GO:0005126cytokine receptor binding ----
GO:0005132type I interferon receptor binding IBA--
     
IFNA17 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IFNA17
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for IFNA17

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IFNA17
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IFNA17

miRNA
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OriGene RNAi products in human, mouse, rat for IFNA17
Predesigned siRNA for gene silencing in human, mouse, rat IFNA17

Gene Editing
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DNA2.0 Custom Protein Engineering Service for IFNA17

Clone
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OriGene clones in human, mouse for IFNA17 (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: IFNA17 (NM_021268)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFNA17
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFNA17

Cell Line
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GenScript Custom overexpressing Cell Line Services for IFNA17
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNA17


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
IFN17_HUMAN, P01571: Secreted
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular5
chloroplast2
nucleus2
cytosol1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region TAS--
GO:0005615extracellular space IBA--

IFNA17 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for IFNA17 About   (see all 21)  
See pathways by source

SuperPathContained pathways About
1Toll-like receptor signaling pathway
Toll-like receptor signaling pathway0.94
Regulation of toll-like receptor signaling pathway0.93
Toll-like receptor signaling pathway0.94
Hepatitis B0.31
2NOD-like Receptor Signaling Pathways
Toll-Like receptor Signaling Pathways0.58
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways0.33
NOD-like Receptor Signaling Pathways0.58
3Immune response IFN alpha beta signaling pathway
Immune response IFN alpha beta signaling pathway0.69
Interferon alpha/beta signaling0.43
Regulation of IFNA signaling0.69
4RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways0.47
TRAF6 mediated IRF7 activation0.40
RIG-I-like receptor signaling pathway0.47
5Influenza A
Influenza A0.34
Herpes simplex infection0.33
Measles0.34

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

2 R&D Systems Pathways for IFNA17
    NOD-like Receptor Signaling Pathways
Toll-Like receptor Signaling Pathways

4 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for IFNA17
    Cytokine Network
Interferon Pathway
JAK-STAT Pathway
all-trans-Retinoic Acid Mediated Apoptosis

2 GeneGo (Thomson Reuters) Pathways for IFNA17
    Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway
Immune response IFN alpha/beta signaling pathway

2 BioSystems Pathways for IFNA17
    Toll-like receptor signaling pathway
Regulation of toll-like receptor signaling pathway

4 Reactome Pathways for IFNA17
    Regulation of IFNA signaling
Interferon alpha/beta signaling
Factors involved in megakaryocyte development and platelet production
TRAF6 mediated IRF7 activation


Selected Kegg Pathways  (Kegg details for IFNA17) (see all 15):
    Cytokine-cytokine receptor interaction
Regulation of autophagy
PI3K-Akt signaling pathway
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway


IFNA17 for pathways           About GeneDecksing

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IFNA17
Interactions:

    Search GeneGlobe Interaction Network for IFNA17

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

4 Interacting proteins for IFNA17 (ENSP000004119404) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
IFNAR1ENSP000002701394STRING: ENSP00000270139
IFNAR2ENSP000003439574STRING: ENSP00000343957
IFNGR1ENSP000003567134STRING: ENSP00000356713
IFNGR2ENSP000002902194STRING: ENSP00000290219
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Gene Ontology (GO): Selected biological process terms (see all 17):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0002250adaptive immune response IBA--
GO:0002286T cell activation involved in immune response IBA--
GO:0002323natural killer cell activation involved in immune response IBA--
GO:0006952defense response ----
GO:0006959humoral immune response IBA--

IFNA17 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for IFNA17 (IFN17)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for IFNA17 gene: 
NM_021268.2  

Unigene Cluster for IFNA17:

Interferon, alpha 17
Hs.282276
Unigene Representative Sequence: M11026
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000413767(uc003zos.1)
Congresses - knowledge worth sharing:
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

miRNA
Products:
     
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Search for qRT-PCR Assays for microRNAs that regulate IFNA17
SwitchGear 3'UTR luciferase reporter plasmidIFNA17 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for IFNA17
Predesigned siRNA for gene silencing in human, mouse, rat IFNA17
Clone
Products:
     
OriGene clones in human, mouse for IFNA17 (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: IFNA17 (NM_021268)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFNA17
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFNA17
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for IFNA17
Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat IFNA17
  QuantiTect SYBR Green Assays in human, mouse, rat IFNA17
  QuantiFast Probe-based Assays in human, mouse, rat IFNA17

Additional mRNA sequence: 

BC096732.1 BC098355.1 M11026.1 M38289.1 M71246.1 

1 DOTS entry:

DT.121210182 

10 AceView cDNA sequences:

NM_021268 BV199643 M71246 M11026 M38289 BV199633 BV199641 BV199638 
BV199640 BV199631 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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IFNA17 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
IFNA17 Expression
About this image

IFNA17 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

IFNA17 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.282276
    Custom PCR Arrays for IFNA17
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for IFNA17
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QuantiFast Probe-based Assays in human, mouse, rat IFNA17
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNA17

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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ENSEMBL Gene Tree for IFNA17 (if available)
TreeFam Gene Tree for IFNA17 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for IFNA17 gene
IFNA72  IFNA22  IFNA42  IFNE2  IFNA142  IFNA52  IFNK2  IFNA12  
IFNA212  IFNA62  IFNB12  IFNA132  IFNW12  IFNA162  IFNA102  IFNA82  
Selected SIMAP similar genes for IFNA17 using alignment to 1 protein entry:     IFN17_HUMAN(see all similar genes):
IFNA4    IFNA10    IFNA21    IFNA5    IFNA7    IFNA14
IFNA16    IFNA    IFN-2    IFNA2    IFNA2B    IFNA1
IFNA13    IFNA6    IFNA8    IFNW1    IFNB1    IFNE

IFNA17 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for IFNA17 (see all 147)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 9 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs120046981,2
C,F,H--21226832(+) TTCACA/GTATCT 1 -- ds50017Minor allele frequency- G:0.07NS NA WA 514
rs1379898091,2
--21226833(+) TCACAA/TATCTG 1 -- ds50010--------
rs1425301831,2
--21226835(+) ACATAG/TCTGAC 1 -- ds50010--------
rs1447513401,2
--21226893(+) TATCTC/GTGCTT 1 -- ds50010--------
rs1854872211,2
--21226997(+) ATTCAA/GCATTA 1 -- ds50010--------
rs1913737001,2
--21227052(+) GAGAAC/GAGGGA 1 -- ds50010--------
rs1418374601,2
--21227077(+) TTCACA/GTTTAT 1 -- ds50010--------
rs78685881,2
C,F,A,H--21227086(+) ATATCT/CTGAAG 1 -- ds50017Minor allele frequency- C:0.34NA WA CSA EA 367
rs1462860541,2
--21227103(+) TATAAC/GCAGGT 1 -- ds50010--------
rs1808583041,2
--21227143(+) TAAAAA/TTATGA 1 -- ds50010--------

HapMap Linkage Disequilibrium report for IFNA17 (21227242 - 21228221 bp)

Structural Variations
     Database of Genomic Variants (DGV) 5 variations for IFNA17:    About this table    
Variant IDTypeSubtypePubMed ID
esv2738279CNV Deletion23290073
esv2738277CNV Deletion23290073
nsv892735CNV Loss21882294
nsv892724CNV Gain21882294
nsv892734CNV Gain21882294

Human Gene Mutation Database (HGMD): IFNA17
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing IFNA17
DNA2.0 Custom Variant and Variant Library Synthesis for IFNA17

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 147583    OMIM disorders: --

Selected diseases for IFNA17 (see all 24):    
About MalaCards
pulmonary sarcoidosis    hiv/aids    dengue hemorrhagic fever    hemorrhagic fever
measles    sarcoidosis    autoimmune thyroiditis    hiv-1
cutaneous malignant melanoma    hepatitis c virus    influenza    hepatitis c
cystic fibrosis    systemic lupus erythematosus    cervical cancer    tuberculosis
multiple sclerosis    lupus erythematosus    hepatitis b    cervicitis

2 diseases from the University of Copenhagen DISEASES database for IFNA17:
Hepatitis C     Hepatitis B

IFNA17 for disorders           About GeneDecksing


Congresses - knowledge worth sharing:
The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014
Genetic Association Database (GAD): IFNA17
Human Genome Epidemiology (HuGE) Navigator: IFNA17 (8 documents)

Export disorders for IFNA17 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for IFNA17 gene, integrated from 10 sources (see all 71):
(articles sorted by number of sources associating them with IFNA17)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Association between IFNA genotype and the risk of sarcoidosis. (PubMed id 15004750)1, 4, 9 Akahoshi M....Shirakawa T. (Hum. Genet. 2004)
  2. Interferon, alpha 17 (IFNA17) Ile184Arg polymorphism and cervical cancer risk. (PubMed id 12490311)1, 4, 9 Kim J.W....Lee H.P. (Cancer Lett. 2003)
  3. Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. (PubMed id 20331378)1, 4 Mosbruger T.L....Thio C.L. (J. Infect. Dis. 2010)
  4. Cystic fibrosis conductance regulator, tumor necrosis factor, interferon alpha-10, interferon alpha-17, and interferon gamma genotyping as potential risk markers in pulmonary sarcoidosis pathogenesis in Greek patients. (PubMed id 20722470)1, 4 Makrythanasis P....Kanavakis E. (Genet Test Mol Biomarkers 2010)
  5. Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations. (PubMed id 20574843)1, 4 Yang X.R....Goldstein A.M. (Fam. Cancer 2010)
  6. Dengue hemorrhagic fever is associated with polymorphisms in JAK1. (PubMed id 20588308)1, 4 Silva L.K....Teixeira M.G. (Eur. J. Hum. Genet. 2010)
  7. Promoter polymorphisms in the IRF3 gene confer protection against systemic lupus erythematosus. (PubMed id 18539711)1, 4 Akahoshi M....Shirakawa T. (Lupus 2008)
  8. No support for a truncated interferon-alpha 17 allele as risk factor for MS. (PubMed id 17956450)1, 4 NystrAPm M....SundstrAPm P. (Eur. J. Neurol. 2007)
  9. A new allele of interferon-alpha17 gene encoding IFN-alpha17b is the major variant in human population. (PubMed id 9712362)1, 2 Hussain M.... Liao M.-J. (J. Interferon Cytokine Res. 1998)
  10. Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes. (PubMed id 9425112)1, 2 Nyman T.A.... Kalkkinen N. (Biochem. J. 1998)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 3451 HGNC: 5422 AceView: IFNA17 Ensembl:ENSG00000234829 euGenes: HUgn3451
ECgene: IFNA17 Kegg: 3451 H-InvDB: IFNA17

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for IFNA17 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for IFNA17 gene:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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