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IFNA10 Gene

protein-coding   GIFtS: 56
GCID: GC09M021252

Interferon, Alpha 10

  See IFNA10-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Interferon, Alpha 101 2     IFN-alpha-102 3
Interferon Alpha-6L2 3     IFN-alphaC2
Interferon Alpha-C2 3     Interferon Alpha-102
LeIF C2 3     

External Ids:    HGNC: 54181   Entrez Gene: 34462   Ensembl: ENSG000001868037   OMIM: 1475775   UniProtKB: P015663   

Export aliases for IFNA10 gene to outside databases

Previous GC identifers: GC09M021533 GC09M021407 GC09M021196 GC09M021215 GC09M021225 GC09M021175 GC09M021232 GC09M021235 GC09M021238 GC09M021242 GC09M021245 GC09M021248


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for IFNA10 Gene:
This gene encodes a protein that belongs to the type I interferon family of proteins, and is located in a cluster
of alpha interferon genes on chromosome 9. Interferons are small regulatory molecules that function in cell
signaling in response to viruses and other pathogens or tumor cells. This gene is intronless and the encoded
protein is secreted. (provided by RefSeq, Aug 2013)

GeneCards Summary for IFNA10 Gene:
IFNA10 (interferon, alpha 10) is a protein-coding gene. Diseases associated with IFNA10 include cortical blindness, and pulmonary sarcoidosis. GO annotations related to this gene include cytokine receptor binding and cytokine activity. An important paralog of this gene is IFNA7.

UniProtKB/Swiss-Prot: IFN10_HUMAN, P01566
Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of
two enzymes: a protein kinase and an oligoadenylate synthetase

Gene Wiki entry for IFNA10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NC_018920.2  NT_008413.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the IFNA10 gene promoter:
         Egr-3   Egr-2   IRF-7A   Egr-4   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for IFNA10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IFNA10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p22   Ensembl cytogenetic band:  9p21.3   HGNC cytogenetic band: 9p22

IFNA10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFNA10 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M021252:  view genomic region     (about GC identifiers)

Start:
21,206,180 bp from pter      End:
21,207,142 bp from pter
Size:
963 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: IFN10_HUMAN, P01566 (See protein sequence)
Recommended Name: Interferon alpha-10 precursor  
Size: 189 amino acids; 21835 Da
Secondary accessions: Q5VV13

Explore the universe of human proteins at neXtProt for IFNA10: NX_P01566

Explore proteomics data for IFNA10 at MOPED


See IFNA10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_002162.1  
ENSEMBL proteins: 
 ENSP00000369566  
Reactome Protein details: P01566

IFNA10 Human Recombinant Protein Products:

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Browse Proteins at Cloud-Clone Corp.

 
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antibodies-online proteins for IFNA10 (7 products) 

 
antibodies-online peptides for IFNA10

IFNA10 Antibody Products:

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LSBio Antibodies in human, mouse, rat for IFNA10
antibodies-online antibodies for IFNA10 (33 products) 

IFNA10 Assay Products:

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antibodies-online kits for IFNA10 (5 products) 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
IFN: Interferons

4 InterPro protein domains:
 IPR012351 4_helix_cytokine_core
 IPR015589 Interferon_alpha
 IPR000471 Interferon_alpha/beta/delta
 IPR009079 4_helix_cytokine-like_core

Graphical View of Domain Structure for InterPro Entry P01566

ProtoNet protein and cluster: P01566

1 Blocks protein domain: IPB000471 Interferon alpha

UniProtKB/Swiss-Prot: IFN10_HUMAN, P01566
Similarity: Belongs to the alpha/beta interferon family


Find genes that share domains with IFNA10           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: IFN10_HUMAN, P01566
Function: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of
two enzymes: a protein kinase and an oligoadenylate synthetase

     Genatlas biochemistry entry for IFNA10:
interferon type I,alpha 10,leukocyte

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005125cytokine activity IBA--
GO:0005126cytokine receptor binding ----
GO:0005132type I interferon receptor binding IBA--
     
Find genes that share ontologies with IFNA10           About GenesLikeMe


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IFNA10
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for IFNA10

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IFNA10
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IFNA10

miRNA
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Block miRNA regulation of human, mouse, rat IFNA10 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate IFNA10:
hsa-miR-4282
SwitchGear 3'UTR luciferase reporter plasmidIFNA10 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for IFNA10
Predesigned siRNA for gene silencing in human, mouse, rat IFNA10

Gene Editing
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OriGene clones in human, mouse for IFNA10 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: IFNA10 (NM_002171)
Sino Biological Human cDNA Clone for IFNA10
DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFNA10
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFNA10

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNA10


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
IFN10_HUMAN, P01566: Secreted
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular5
cytosol1
nucleus1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region TAS--
GO:0005615extracellular space IBA--

Find genes that share ontologies with IFNA10           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for IFNA10 About   (see all 21)  
See pathways by source

SuperPathContained pathways About
1Toll-like receptor signaling pathway
Toll-like receptor signaling pathway0.94
Regulation of toll-like receptor signaling pathway0.93
Toll-like receptor signaling pathway0.94
Hepatitis B0.31
2Immune response IFN alpha beta signaling pathway
Immune response IFN alpha beta signaling pathway0.69
Interferon alpha/beta signaling0.43
Regulation of IFNA signaling0.69
3NOD-like Receptor Signaling Pathways
Toll-Like receptor Signaling Pathways0.58
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways0.33
NOD-like Receptor Signaling Pathways0.58
4RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways0.47
TRAF6 mediated IRF7 activation0.40
RIG-I-like receptor signaling pathway0.47
5Influenza A
Influenza A0.34
Herpes simplex infection0.33
Measles0.34


Find genes that share SuperPaths with IFNA10           About GenesLikeMe

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

2 R&D Systems Pathways for IFNA10
    NOD-like Receptor Signaling Pathways
Toll-Like receptor Signaling Pathways

4 Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for IFNA10
    Cytokine Network
Interferon Pathway
JAK-STAT Pathway
all-trans-Retinoic Acid Mediated Apoptosis

2 GeneGo (Thomson Reuters) Pathways for IFNA10
    Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway
Immune response IFN alpha/beta signaling pathway

2 BioSystems Pathways for IFNA10
    Toll-like receptor signaling pathway
Regulation of toll-like receptor signaling pathway


4 Reactome Pathways for IFNA10
    Regulation of IFNA signaling
Interferon alpha/beta signaling
Factors involved in megakaryocyte development and platelet production
TRAF6 mediated IRF7 activation


Selected Kegg Pathways  (Kegg details for IFNA10) (see all 15):
    Cytokine-cytokine receptor interaction
Regulation of autophagy
PI3K-Akt signaling pathway
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for IFNA10
Interactions:

    Search GeneGlobe Interaction Network for IFNA10

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

4 Interacting proteins for IFNA10 (ENSP000003695664) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
IFNAR1ENSP000002701394STRING: ENSP00000270139
IFNAR2ENSP000003439574STRING: ENSP00000343957
IFNGR1ENSP000003567134STRING: ENSP00000356713
IFNGR2ENSP000002902194STRING: ENSP00000290219
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Gene Ontology (GO): Selected biological process terms (see all 16):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0002250adaptive immune response IBA--
GO:0002286T cell activation involved in immune response IBA--
GO:0002323natural killer cell activation involved in immune response IBA--
GO:0006952defense response ----
GO:0006959humoral immune response IBA--

Find genes that share ontologies with IFNA10           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for IFNA10 (IFN10)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for IFNA10 gene: 
NM_002171.2  

Unigene Cluster for IFNA10:

Interferon, alpha 10
Hs.282275
Unigene Representative Sequence: NM_002171
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000357374(uc003zoq.1)
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat IFNA10 using miScript Target Protectors
1 qRT-PCR Assays for microRNA that regulate IFNA10:
hsa-miR-4282
SwitchGear 3'UTR luciferase reporter plasmidIFNA10 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for IFNA10
Predesigned siRNA for gene silencing in human, mouse, rat IFNA10
Clone
Products:
     
OriGene clones in human, mouse for IFNA10 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: IFNA10 (NM_002171)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFNA10
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFNA10
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for IFNA10
Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat IFNA10
  QuantiTect SYBR Green Assays in human, mouse, rat IFNA10
  QuantiFast Probe-based Assays in human, mouse, rat IFNA10

Additional mRNA sequence: 

BC069409.1 BC103972.2 BC103973.1 V00551.1 

1 DOTS entry:

DT.121210182 

3 AceView cDNA sequences:

BC069409 NM_002171 V00551 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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IFNA10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
IFNA10 Expression
About this image

IFNA10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

IFNA10 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.282275
    Custom PCR Arrays for IFNA10
Primer
Products:
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFNA10

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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  --

ENSEMBL Gene Tree for IFNA10 (if available)
TreeFam Gene Tree for IFNA10 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for IFNA10 gene
IFNA72  IFNA22  IFNA42  IFNE2  IFNA142  IFNA52  IFNK2  IFNA12  
IFNA212  IFNA172  IFNA62  IFNB12  IFNA132  IFNW12  IFNA162  IFNA82  
Selected SIMAP similar genes for IFNA10 using alignment to 1 protein entry:     IFN10_HUMAN(see all similar genes):
IFNA17    IFNA4    IFNA7    IFNA21    IFNA14    IFNA5
IFNA16    IFNA    IFNA2    IFNA6    IFNA8    IFN-2
IFNA1    IFNA13    IFNA2B    IFNW1    IFNB1    IFNE

Find genes that share paralogs with IFNA10           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for IFNA10 (see all 158)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 9 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1909437581,2
--21205688(+) CCCCAC/TATGAC 1 -- ds50010--------
rs283681541,2
C,F--21205708(-) AAAGGA/CCGCAA 1 -- ds50012Minor allele frequency- C:0.06WA NA 238
rs1427499761,2
--21205830(+) TATCTC/GTGCTT 1 -- ds50010--------
rs283681521,2
C--21205943(-) AACAAC/TAATAA 1 -- ds50010--------
rs2001509351,2
C--21205966(+) CCTGA-/CAAAAA 1 -- ds50010--------
rs3726821381,2
C--21205980(+) AAGATA/C/GAAGAG 1 -- ds50010--------
rs283681511,2
C,F--21206081(-) TCATAA/CTTTTA 1 -- ds50012Minor allele frequency- C:0.06WA NA 238
rs1391259131,2
--21206093(+) AGGTAA/TCATAA 1 -- ds50010--------
rs1834665031,2
--21206155(+) CTTAAA/GGAATA 1 -- ds50010--------
rs283681501,2
C--21206174(-) AAAATA/TTCTTG 1 -- ds50010--------

HapMap Linkage Disequilibrium report for IFNA10 (21206180 - 21207142 bp)

Structural Variations
     Database of Genomic Variants (DGV) 9 variations for IFNA10:    About this table    
Variant IDTypeSubtypePubMed ID
esv2738274CNV Deletion23290073
dgv1305e201CNV Deletion23290073
esv2738277CNV Deletion23290073
nsv516132CNV Loss19592680
nsv892735CNV Loss21882294
esv6326CNV Loss19470904
nsv892724CNV Gain21882294
nsv892734CNV Gain21882294
nsv8425CNV Gain+Loss18304495

Human Gene Mutation Database (HGMD): IFNA10
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing IFNA10
DNA2.0 Custom Variant and Variant Library Synthesis for IFNA10

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 147577    OMIM disorders: --

6 diseases for IFNA10:    
About MalaCards
cortical blindness    pulmonary sarcoidosis    hiv/aids    dengue hemorrhagic fever
cutaneous malignant melanoma    hiv-1

1 disease from the University of Copenhagen DISEASES database for IFNA10:
Cortical blindness

Find genes that share disorders with IFNA10           About GenesLikeMe

2 Novoseek inferred disease relationships for IFNA10 gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
metastatic renal cell carcinoma 76.9 4 2144747 (1), 2222899 (1), 2250479 (1), 1746062 (1)
dementia 26.1 1 1746062 (1)

Genetic Association Database (GAD): IFNA10
Human Genome Epidemiology (HuGE) Navigator: IFNA10 (5 documents)

Export disorders for IFNA10 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for IFNA10 gene, integrated from 10 sources (see all 71):
(articles sorted by number of sources associating them with IFNA10)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus. (PubMed id 20331378)1, 4 Mosbruger T.L....Thio C.L. (J. Infect. Dis. 2010)
  2. Cystic fibrosis conductance regulator, tumor necrosis factor, interferon alpha-10, interferon alpha-17, and interferon gamma genotyping as potential risk markers in pulmonary sarcoidosis pathogenesis in Greek patients. (PubMed id 20722470)1, 4 Makrythanasis P....Kanavakis E. (Genet Test Mol Biomarkers 2010)
  3. Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations. (PubMed id 20574843)1, 4 Yang X.R....Goldstein A.M. (Fam. Cancer 2010)
  4. Dengue hemorrhagic fever is associated with polymorphisms in JAK1. (PubMed id 20588308)1, 4 Silva L.K....Teixeira M.G. (Eur. J. Hum. Genet. 2010)
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  6. Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes. (PubMed id 9425112)1, 2 Nyman T.A.... Kalkkinen N. (Biochem. J. 1998)
  7. Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia. (PubMed id 1385305)1, 3 Olopade O.I....Diaz M.O. (Genomics 1992)
  8. Identification of a functional allele of a human interferon-alpha gene previously characterized as a pseudogene. (PubMed id 2526839)1, 2 Bartholomew C. and Windass J.D. (J. Interferon Res. 1989)
  9. The structure of eight distinct cloned human leukocyte interferon cDNAs. (PubMed id 6163083)1, 2 Goeddel D.V.... Gray P.W. (Nature 1981)
  10. Subtypes of type I IFN differentially enhance cytokine expression by suboptimally stimulated CD4(+) T cells. (PubMed id 24030809)1 Hillyer P....Rabin R.L. (Eur. J. Immunol. 2013)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 3446 HGNC: 5418 AceView: IFNA10 Ensembl:ENSG00000186803 euGenes: HUgn3446
ECgene: IFNA10 Kegg: 3446 H-InvDB: IFNA10

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for IFNA10 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for IFNA10 gene:
Search GeneIP for patents involving IFNA10

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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