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IFI44L Gene

protein-coding   GIFtS: 45
GCID: GC01P079085

Interferon-Induced Protein 44-Like

(Previous name: chromosome 1 open reading frame 29)
(Previous symbol: C1orf29)
  Search for IFI44L
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Interferon-Induced Protein 44-Like1 2
C1orf291 2 3
Chromosome 1 Open Reading Frame 291

External Ids:    HGNC: 178171   Entrez Gene: 109642   Ensembl: ENSG000001379597   OMIM: 6139755   UniProtKB: Q53G443   

Export aliases for IFI44L gene to outside databases

Previous GC identifers: GC01P078799 GC01P078858 GC01P077217


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IFI44L Gene:
IFI44L (interferon-induced protein 44-like) is a protein-coding gene. An important paralog of this gene is IFI44.

UniProtKB/Swiss-Prot: IF44L_HUMAN, Q53G44
Function: Exhibits a low antiviral activity against hepatitis C virus




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the IFI44L gene promoter:
         C/EBPbeta   LHX3b/Lhx3b   POU2F1   POU2F1b   POU2F1a   LHX3a/Lhx3a   POU2F1c   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIFI44L promoter sequence
   Search Chromatin IP Primers for IFI44L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IFI44L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p31.1   Ensembl cytogenetic band:  1p31.1   HGNC cytogenetic band: 1p22.3

IFI44L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFI44L gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P079085:  view genomic region     (about GC identifiers)

Start:
79,085,607 bp from pter      End:
79,111,830 bp from pter
Size:
26,224 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: IF44L_HUMAN, Q53G44 (See protein sequence)
Recommended Name: Interferon-induced protein 44-like  
Size: 452 amino acids; 51322 Da
Sequence caution: Sequence=AAH15932.1; Type=Erroneous initiation; Sequence=BAA19056.1; Type=Frameshift;
Positions=18; Sequence=BAD96807.1; Type=Erroneous initiation;
Secondary accessions: Q86TE1 Q96B64 Q99984
Alternative splicing: 2 isoforms:  Q53G44-1   Q53G44-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for IFI44L: NX_Q53G44

Explore proteomics data for IFI44L at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See IFI44L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006811.2  
    ENSEMBL proteins: 
     ENSP00000409914   ENSP00000359787   ENSP00000400784   ENSP00000342833  

    IFI44L Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for IFI44L

     
    Search eBioscience for Proteins for IFI44L 

    IFI44L Antibody Products:

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    LSBio Antibodies in human, mouse, rat for IFI44L

    IFI44L Assay Products:

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    Cloud-Clone Corp. CLIAs for IFI44L
    Search eBioscience for ELISAs for IFI44L 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR024644 IFI44_fam
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry Q53G44

    ProtoNet protein and cluster: Q53G44

    UniProtKB/Swiss-Prot: IF44L_HUMAN, Q53G44
    Similarity: Belongs to the IFI44 family


    Find genes that share domains with IFI44L           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IF44L_HUMAN, Q53G44
    Function: Exhibits a low antiviral activity against hepatitis C virus
    Induction: By type I interferons

    Phenotypes:
         1 GenomeRNAi human phenotype for IFI44L:

     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IFI44L
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for IFI44L

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IFI44L
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IFI44L

    miRNA
    Products:
        
    miRTarBase miRNAs that target IFI44L:
    hsa-mir-124-3p (MIRT022604), hsa-mir-146a-5p (MIRT021253)

    Block miRNA regulation of human, mouse, rat IFI44L using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate IFI44L:
    hsa-miR-1304 hsa-miR-4254 hsa-miR-205 hsa-miR-450b-5p hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidIFI44L 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for IFI44L
    Predesigned siRNA for gene silencing in human, mouse, rat IFI44L

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for IFI44L

    Clone
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    OriGene clones in human, mouse for IFI44L (see all 9)
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    GenScript: all cDNA clones in your preferred vector: IFI44L (NM_006820)
    Sino Biological Human cDNA Clone for IFI44L
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFI44L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFI44L

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for IFI44L 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFI44L


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IF44L_HUMAN, Q53G44: Cytoplasm (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with IFI44L           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including IFI44L: 
              Interferons & Receptors in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for IFI44L

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response IEA--
    GO:0051607defense response to virus IEA--

    Find genes that share ontologies with IFI44L           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IFI44L (IF44L)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for IFI44L gene: 
    NM_006820.2  

    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000452835 ENST00000476521 ENST00000370751(uc010oro.2 uc010orp.2 uc010orq.2)
    ENST00000459784 ENST00000476876 ENST00000486882 ENST00000462041 ENST00000450498
    ENST00000474002 ENST00000494910 ENST00000342282
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat IFI44L using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate IFI44L:
    hsa-miR-1304 hsa-miR-4254 hsa-miR-205 hsa-miR-450b-5p hsa-miR-548c-3p
    SwitchGear 3'UTR luciferase reporter plasmidIFI44L 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for IFI44L
    Predesigned siRNA for gene silencing in human, mouse, rat IFI44L
    Clone
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    OriGene clones in human, mouse for IFI44L (see all 9)
    OriGene ORF clones in mouse, rat for IFI44L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IFI44L (NM_006820)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFI44L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFI44L
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for IFI44L
    OriGene qSTAR qPCR primer pairs in human, mouse for IFI44L
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IFI44L
      QuantiTect SYBR Green Assays in human, mouse, rat IFI44L
      QuantiFast Probe-based Assays in human, mouse, rat IFI44L

    Selected AceView cDNA sequences (see all 115):

    AA938694 AI342415 BC015932 AI051147 AA410188 AI422859 AI686888 CD106974 
    AI682015 CA390015 BM904203 BU856905 CA423461 AA243416 BU616973 AI282423 
    BX501650 BQ219494 AI361921 F12860 BU517170 F10462 AW193245 AA303544 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for IFI44L (see all 12)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e · 2f ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c · 5d ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b · 10c ^ 11a · 11b ^
    SP1:                                            -     -     -     -                             -                       -                                       
    SP2:                                            -     -     -     -     -     -     -           -                       -     -                                 
    SP3:                                                                                            -                       -                                       
    SP4:                                            -     -     -     -     -     -     -           -                       -                                       
    SP5:                                            -     -     -     -     -     -     -           -                       -     -                                 

    ExUns: 12a · 12b ^ 13a · 13b · 13c
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for IFI44L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IFI44L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    IFI44L Expression
    About this image


    IFI44L expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Neural Crest (Gastrulation Derivatives)    fully expand to see all 3 entries
             PureStem SK11, NCr-fac & Meso-prx Progenitor
     
     Paraxial Mesoderm (Gastrulation Derivatives)    fully expand to see all 2 entries
             PureStem SK11, NCr-fac & Meso-prx Progenitor
     
     Thymus (Hematopoietic System)    fully expand to see all 2 entries
             T Helper Cells Thymus
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             T Helper Cells Thymus
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Muscle Progenitor Cells Mandibular Arch Muscles
    IFI44L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IFI44L Protein Expression
        Pathway & Disease-focused RT2 Profiler PCR Array including IFI44L: 
              Interferons & Receptors in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for IFI44L
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IFI44L
    QuantiTect SYBR Green Assays in human, mouse, rat IFI44L
    QuantiFast Probe-based Assays in human, mouse, rat IFI44L
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFI44L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for IFI44L gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ifi44l1 , 5 histocompatibility 285
    interferon-induced protein 44 like1
    65.98(n)1
    53.1(a)1
      3 (76.94 cM)5
    150611  NM_031367.11  NP_112735.11 
     1517596415 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 4)
    Uncharacterized protein
    (see all 4)
    51(a)
    42(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    GL343194.1(5115588-5115764)
    GL343194.1(5168586-5175593)
    zebrafish
    (Danio rerio)
    Actinopterygii CR855320.16
    zgc:1536546
    (see all 20)
    zgc:153654
    (see all 20)
    36(a)
    34(a)
    (see all 20)
    many ↔ many
    many ↔ many
    (see all 20)
    1(6928646-6930673) ENSDARG00000092634
    2(36634957-36639542) ENSDARG00000060322


    ENSEMBL Gene Tree for IFI44L (if available)
    TreeFam Gene Tree for IFI44L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IFI44L gene
    IFI442  
    1 SIMAP similar gene for IFI44L using alignment to 4 protein entries:     IF44L_HUMAN (see all proteins):
    IFI44

    Find genes that share paralogs with IFI44L           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IFI44L (see all 674)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs749147921,2
    C,F--79084115(+) GTGACA/GGTTCC 1 -- us2k11Minor allele frequency- G:0.07EA 120
    rs1931983981,2
    --79084129(+) GTCTTC/TCCTTG 1 -- us2k10--------
    rs1855051601,2
    --79084149(+) ATCTTC/GACACT 1 -- us2k10--------
    rs1907574731,2
    --79084189(+) ATGTCC/TTTCAG 1 -- us2k10--------
    rs2732391,2
    C--79084289(-) caggtA/Gcccca 1 -- us2k15Minor allele frequency- G:0.08NA WA EA 362
    rs1430090361,2
    --79084332(+) TTGATC/TGTTTA 1 -- us2k10--------
    rs1475650721,2
    C--79084380(+) TACTG-/TTTTTT 1 -- us2k10--------
    rs1474742091,2
    --79084633(+) ATATCA/GGTATA 1 -- us2k10--------
    rs1925928421,2
    --79084699(+) AAATTC/GTTCGG 1 -- us2k10--------
    rs1158978211,2
    C,F--79084703(+) TGTTCG/AGCTTT 1 -- us2k11Minor allele frequency- A:0.02NA 120

    HapMap Linkage Disequilibrium report for IFI44L (79085607 - 79111830 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for IFI44L:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2661424CNV Deletion23128226
    esv2750218CNV Deletion23290073
    esv274113CNV Insertion20981092
    esv267842CNV Insertion20981092
    nsv871140CNV Gain21882294
    nsv830315CNV Gain17160897
    nsv871835CNV Gain21882294

    Human Gene Mutation Database (HGMD): IFI44L
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IFI44L
    DNA2.0 Custom Variant and Variant Library Synthesis for IFI44L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613975    OMIM disorders: --


    Find genes that share disorders with IFI44L           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: IFI44L (1 document)

    Export disorders for IFI44L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IFI44L gene integrated from 10 sources:
    (articles sorted by number of sources associating them with IFI44L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. (PubMed id 23453885)1 (Lancet 2013)
    2. A diverse range of gene products are effectors of the type I interferon antiviral response. (PubMed id 21478870)2 Schoggins J.W.... Rice C.M. (Nature 2011)
    3. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)
    4. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    6. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)1 Maruyama K. and Sugano S. (Gene 1994)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10964 HGNC: 17817 AceView: C1orf29 Ensembl:ENSG00000137959 euGenes: HUgn10964
    ECgene: IFI44L H-InvDB: IFI44L

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IFI44L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IFI44L gene:
    Search GeneIP for patents involving IFI44L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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