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IFI44 Gene

protein-coding   GIFtS: 52
GCID: GC01P079115

Interferon-Induced Protein 44

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Interferon-Induced Protein 441 2     p442 3
TBC/LysM-Associated Domain Containing 51 2     TLDC52
Microtubule-Associated Protein 442 3     Interferon-Induced, Hepatitis C-Associated Microtubular Aggregate Protein
(44kD)2
MTAP442 3     P445

External Ids:    HGNC: 169381   Entrez Gene: 105612   Ensembl: ENSG000001379657   OMIM: 6104685   UniProtKB: Q8TCB03   

Export aliases for IFI44 gene to outside databases

Previous GC identifers: GC01P079275 GC01P078014 GC01P078506 GC01P078538 GC01P078827 GC01P078888 GC01P077247


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IFI44 Gene:
IFI44 (interferon-induced protein 44) is a protein-coding gene. Diseases associated with IFI44 include hepatitis c, and hepatitis. An important paralog of this gene is IFI44L.

UniProtKB/Swiss-Prot: IFI44_HUMAN, Q8TCB0
Function: This protein aggregates to form microtubular structures (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the IFI44 gene promoter:
         TBP   Bach1   Tal-1   Pbx1a   Bach2   STAT5A   CUTL1   IRF-1   TFIID   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIFI44 promoter sequence
   Search Chromatin IP Primers for IFI44

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IFI44


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p31.1   Ensembl cytogenetic band:  1p31.1   HGNC cytogenetic band: 1p31.1

IFI44 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFI44 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P079115:  view genomic region     (about GC identifiers)

Start:
79,115,477 bp from pter      End:
79,129,763 bp from pter
Size:
14,287 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: IFI44_HUMAN, Q8TCB0 (See protein sequence)
Recommended Name: Interferon-induced protein 44  
Size: 444 amino acids; 50491 Da
Secondary accessions: D3DQ80 Q14496

Explore the universe of human proteins at neXtProt for IFI44: NX_Q8TCB0

Explore proteomics data for IFI44 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See IFI44 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006408.3  
    ENSEMBL proteins: 
     ENSP00000359783   ENSP00000399477   ENSP00000400001   ENSP00000437973  

    IFI44 Human Recombinant Protein Products:

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    LSBio Antibodies in human, mouse, rat for IFI44

    IFI44 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for IFI44
    Cloud-Clone Corp. CLIAs for IFI44


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR024644 IFI44_fam
     IPR027417 P-loop_NTPase
     IPR006571 TLDc

    Graphical View of Domain Structure for InterPro Entry Q8TCB0

    ProtoNet protein and cluster: Q8TCB0

    UniProtKB/Swiss-Prot: IFI44_HUMAN, Q8TCB0
    Similarity: Belongs to the IFI44 family


    IFI44 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IFI44_HUMAN, Q8TCB0
    Function: This protein aggregates to form microtubular structures (By similarity)
    Induction: By alpha and beta interferons, but not by gamma interferons

    Phenotypes:
         1 GenomeRNAi human phenotype for IFI44:

     Decreased DCP1a protein expres 

         1 MGI phenotypic allele for Ifi44 (no phenotypes)

    IFI44 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IFI44
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for IFI44

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IFI44
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IFI44

    miRNA
    Products:
        
    miRTarBase miRNAs that target IFI44:
    hsa-mir-26b-5p (MIRT029611), hsa-mir-146a-5p (MIRT021249), hsa-mir-1 (MIRT023845)

    Block miRNA regulation of human, mouse, rat IFI44 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate IFI44
    SwitchGear 3'UTR luciferase reporter plasmidIFI44 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for IFI44
    Predesigned siRNA for gene silencing in human, mouse, rat IFI44

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for IFI44

    Clone
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    OriGene clones in human, mouse for IFI44 (see all 6)
    OriGene ORF clones in mouse, rat for IFI44
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    GenScript: all cDNA clones in your preferred vector: IFI44 (NM_006417)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFI44
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFI44

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for IFI44 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFI44


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IFI44_HUMAN, Q8TCB0: Cytoplasm (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    mitochondrion2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    IFI44 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including IFI44: 
              Interferons & Receptors in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for IFI44

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for IFI44 (ENSP000003597834) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KNCNENSP000003796074STRING: ENSP00000379607
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009615response to virus TAS7925411

    IFI44 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IFI44



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for IFI44 gene: 
    NM_006417.4  

    Unigene Cluster for IFI44:

    Interferon-induced protein 44
    Hs.82316  [show with all ESTs]
    Unigene Representative Sequence: BX537508
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000470323 ENST00000370747(uc001dip.4) ENST00000438486 ENST00000495254
    ENST00000467790 ENST00000472152 ENST00000485662 ENST00000476911 ENST00000446486
    ENST00000545124(uc010orr.1 uc010ors.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat IFI44 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate IFI44
    SwitchGear 3'UTR luciferase reporter plasmidIFI44 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for IFI44
    Predesigned siRNA for gene silencing in human, mouse, rat IFI44
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    OriGene clones in human, mouse for IFI44 (see all 6)
    OriGene ORF clones in mouse, rat for IFI44
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IFI44 (NM_006417)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFI44
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFI44
    Primer
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    OriGene qPCR primer pairs and template standards for IFI44
    OriGene qSTAR qPCR primer pairs in human, mouse for IFI44
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IFI44
      QuantiTect SYBR Green Assays in human, mouse, rat IFI44
      QuantiFast Probe-based Assays in human, mouse, rat IFI44

    Additional mRNA sequence: 

    AK302527.1 AK316278.1 AK316476.1 BC022870.1 BX537508.1 

    12 DOTS entries:

    DT.444841  DT.100714496  DT.95370300  DT.100025567  DT.100790776  DT.121412969  DT.95303647  DT.100025569 
    DT.121412952  DT.92428028  DT.95370299  DT.121412962 

    Selected AceView cDNA sequences (see all 116):

    BM547313 AI472619 CR621445 AW204634 CA423905 BQ775060 AI086345 C05190 
    BU167907 AI275105 BQ772889 BQ437856 CA426666 AA476308 BE049439 AA480136 
    AA464178 AA476356 AI290106 CB151546 BX645196 BG661331 AI358603 BU675262 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for IFI44 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b · 9c
    SP1:                                                                                -                                 
    SP2:              -                                                                                                   
    SP3:              -     -                                               -     -     -                                 
    SP4:              -     -                                                                                             
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for IFI44

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IFI44 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTTAGTCAT
    IFI44 Expression
    About this image


    IFI44 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Endothelium (Cardiovascular System)    fully expand to see all 3 entries
             Adult Endothelial Cells Blood Brain Barrier
             Human umbilical vein endothelial cells (HUVEC)
             Endothelial-like cells
     
     Thymus (Hematopoietic System)    fully expand to see all 2 entries
             T Helper Cells Thymus
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             T Helper Cells Thymus
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Brain (Nervous System)
             Adult Endothelial Cells Blood Brain Barrier
    IFI44 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IFI44 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.82316
        Pathway & Disease-focused RT2 Profiler PCR Array including IFI44: 
              Interferons & Receptors in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFI44

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for IFI44 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ifi441 , 5 interferon-induced protein 441, 5 69.76(n)1
    57.38(a)1
      3 (76.91 cM)5
    998991  NM_133871.21  NP_598632.21 
     1517309225 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 4)
    Uncharacterized protein
    (see all 4)
    58(a)
    39(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    GL343194.1(5115588-5115764)
    GL343194.1(5168586-5175593)
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch211-197g15.61 si:ch211-197g15.6 47.82(n)
    39.33(a)
      571364  NM_001045218.1  NP_001038683.1 


    ENSEMBL Gene Tree for IFI44 (if available)
    TreeFam Gene Tree for IFI44 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IFI44 gene
    IFI44L2  
    1 SIMAP similar gene for IFI44 using alignment to 4 protein entries:     IFI44_HUMAN (see all proteins):
    IFI44L

    IFI44 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IFI44 (see all 416)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1838414901,2
    --79113542(+) TTTCTC/TCCCAG 1 -- us2k10--------
    rs1876284461,2
    --79113575(+) CCCATA/TGCCAG 1 -- us2k10--------
    rs1176648751,2
    C,F--79113677(+) TCAGGT/ATTAAA 1 -- us2k11Minor allele frequency- A:0.03EA 120
    rs1465438671,2
    C--79113707(+) CAGGGA/GCAAAA 1 -- us2k10--------
    rs111625221,2
    --79113752(+) ACTTTA/TGCTCC 1 -- us2k10--------
    rs1906981771,2
    --79113811(+) CTTTAC/TTGTCC 1 -- us2k10--------
    rs1827046941,2
    --79113827(+) ACTATA/CAGCAT 1 -- us2k10--------
    rs570274321,2
    C,F--79113889(+) ATTTTG/ATCTTC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1157182611,2
    C,F--79113944(+) AAAGTT/GGCTTC 1 -- us2k11Minor allele frequency- G:0.01NA 120
    rs1867138431,2
    C--79113946(+) AGTTGC/TTTCCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for IFI44 (79115477 - 79129763 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for IFI44:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2677291CNV Deletion23128226
    nsv871140CNV Gain21882294
    nsv830315CNV Gain17160897
    nsv871835CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IFI44
    DNA2.0 Custom Variant and Variant Library Synthesis for IFI44

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610468    OMIM disorders: --

    5 diseases for IFI44:    
    About MalaCards
    hepatitis c    hepatitis    hepatitis b    hiv-1
    endotheliitis

    1 disease from the University of Copenhagen DISEASES database for IFI44:
    Hepatitis C

    IFI44 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for IFI44 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hepatitis delta 71.8 1 7925411 (1)

    Genetic Association Database (GAD): IFI44
    Human Genome Epidemiology (HuGE) Navigator: IFI44 (3 documents)

    Export disorders for IFI44 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IFI44 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with IFI44)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Induction of the human gene for p44, a hepatitis-C-associated microtubular aggregate protein, by interferon-alpha/beta. (PubMed id 7925411)1, 2, 3, 9 Kitamura A.... Kitamura N. (Eur. J. Biochem. 1994)
    2. Genetic predisposition of responsiveness to therapy for chronic hepatitis C. (PubMed id 16886895)1, 4, 9 Hwang Y....Chen D.S. (Pharmacogenomics 2006)
    3. Polymorphisms of interferons and their receptors in the genetics of severe RSV-associated diseases. (PubMed id 18953482)1, 4 Mailaparambil B....Heinzmann A. (Arch. Virol. 2008)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. (PubMed id 23453885)1 (Lancet 2013)
    6. Viperin, MTAP44, and protein kinase R contribute to the interferon-induced inhibition of Bunyamwera Orthobunyavirus replication. (PubMed id 22896602)1 Carlton-Smith C. and Elliott R.M. (J. Virol. 2012)
    7. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (J. Biol. Chem. 2011)
    8. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    9. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (Genes Immun. 2010)
    10. A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. (PubMed id 19460752)1 Yeung M.L....Jeang K.T. (J. Biol. Chem. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10561 HGNC: 16938 AceView: IFI44 Ensembl:ENSG00000137965 euGenes: HUgn10561
    ECgene: IFI44 H-InvDB: IFI44

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for IFI44 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IFI44 gene:
    Search GeneIP for patents involving IFI44

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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