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IFI35 Gene

protein-coding   GIFtS: 55
GCID: GC17P041158

Interferon-Induced Protein 35

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Interferon-Induced Protein 351 2
IFP352 3
IFP 352 3
ifi-352
Interferon-Induced 35 KDa Protein2
Ifi-353

External Ids:    HGNC: 53991   Entrez Gene: 34302   Ensembl: ENSG000000680797   OMIM: 6007355   UniProtKB: P802173   

Export aliases for IFI35 gene to outside databases

Previous GC identifers: GC17M062367 GC17P043320 GC17P041067 GC17P041532 GC17P041533 GC17P038412 GC17P036924


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for IFI35 Gene:
IFI35 (interferon-induced protein 35) is a protein-coding gene. Diseases associated with IFI35 include diverticulitis, and ovarian cancer. An important paralog of this gene is NMI.

UniProtKB/Swiss-Prot: IN35_HUMAN, P80217
Function: Not yet known

Gene Wiki entry for IFI35 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the IFI35 gene promoter:
         SRF   HOXA9   HOXA9B   SRF (504 AA)   RREB-1   MyoD   C/EBPalpha   IRF-7A   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidIFI35 promoter sequence
   Search Chromatin IP Primers for IFI35

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat IFI35


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21   Ensembl cytogenetic band:  17q21.31   HGNC cytogenetic band: 17q21

IFI35 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFI35 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P041158:  view genomic region     (about GC identifiers)

Start:
41,158,742 bp from pter      End:
41,166,476 bp from pter
Size:
7,735 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: IN35_HUMAN, P80217 (See protein sequence)
Recommended Name: Interferon-induced 35 kDa protein  
Size: 286 amino acids; 31546 Da
Subunit: Homodimer. Also interacts with B-ATF
Sequence caution: Sequence=AAB61703.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of
unknown origin in the N-terminal part;
Secondary accessions: C9JGX1 Q92984 Q99537 Q9BV98
Alternative splicing: 2 isoforms:  P80217-1   P80217-2   (Variant in position: 128:M->V (in dbSNP:rs588703). Due to a polymorphism at the 3'-splice acceptor site of intron 4)

Explore the universe of human proteins at neXtProt for IFI35: NX_P80217

Explore proteomics data for IFI35 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys221
  • Modification sites at PhosphoSitePlus

  • See IFI35 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005524.2  
    ENSEMBL proteins: 
     ENSP00000394579   ENSP00000395590  
    Reactome Protein details: P80217

    IFI35 Human Recombinant Protein Products:

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    Novus Biologicals IFI35 Proteins
    Novus Biologicals IFI35 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for IFI35

    IFI35 Antibody Products:

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    ThermoFisher Antibodies for IFI35
    LSBio Antibodies in human, mouse, rat for IFI35

    IFI35 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for IFI35
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for IFI35
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for IFI35
    Cloud-Clone Corp. CLIAs for IFI35


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR009938 Nmi/IFP35_N
     IPR009909 Nmi/IFP35_dom

    Graphical View of Domain Structure for InterPro Entry P80217

    ProtoNet protein and cluster: P80217

    1 Blocks protein domain: IPB009909 Nmi/IFP 35

    UniProtKB/Swiss-Prot: IN35_HUMAN, P80217
    Similarity: Belongs to the NMI family


    IFI35 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IN35_HUMAN, P80217
    Function: Not yet known
    Induction: By interferon gamma

         Genatlas biochemistry entry for IFI35:
    interferon-induced leucine zipper protein IFI35,may be the same as APRF

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18624398
         
    IFI35 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for IFI35
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for IFI35

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for IFI35
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for IFI35

    miRNA
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    Block miRNA regulation of human, mouse, rat IFI35 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate IFI35:
    hsa-miR-589
    SwitchGear 3'UTR luciferase reporter plasmidIFI35 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for IFI35
    Predesigned siRNA for gene silencing in human, mouse, rat IFI35

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for IFI35

    Clone
    Products:
         
    OriGene clones in human, mouse for IFI35 (see all 8)
    OriGene ORF clones in mouse, rat for IFI35
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IFI35 (NM_005533)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFI35
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFI35

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for IFI35
    Browse ESI BIO Cell Lines and PureStem Progenitors for IFI35 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFI35


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    IN35_HUMAN, P80217: Nucleus. Note=Nuclear following IFN treatment
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol4
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA8288566
    GO:0005829cytosol TAS--

    IFI35 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for IFI35 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Interferon Signaling
    Interferon Signaling0.59
    Cytokine Signaling in Immune system0.59
    2Immune response IFN alpha beta signaling pathway
    Interferon alpha/beta signaling0.43

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for IFI35
        Interferon alpha/beta signaling



    IFI35 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Array including IFI35: 
              Interferons & Receptors in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for IFI35

    5 Interacting proteins for IFI35 (P802171, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CLEC4GQ6UXB41, 3EBI-2115067,EBI-2114729 I2D: score=2 
    BATFQ165203I2D: score=3 
    NMIQ132873I2D: score=3 
    PLEKHO1Q53GL03I2D: score=3 
    MAPK1P284823I2D: score=2 
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response ----
    GO:0009615response to virus ----
    GO:0019221cytokine-mediated signaling pathway TAS--
    GO:0060337type I interferon signaling pathway TAS--

    IFI35 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for IFI35 (IN35)

    1 Novoseek inferred chemical compound relationship for IFI35 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leucine 58.5 7 8288566 (3), 8938427 (1), 8668343 (1), 8954125 (1)



    IFI35 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for IFI35 gene: 
    NM_005533.4  

    Unigene Cluster for IFI35:

    Interferon-induced protein 35
    Hs.632258  [show with all ESTs]
    Unigene Representative Sequence: BU539084
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000415816(uc021txx.1) ENST00000438323 ENST00000246911 ENST00000536969
    ENST00000396722 ENST00000538473 ENST00000546325 ENST00000534876
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat IFI35 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate IFI35:
    hsa-miR-589
    SwitchGear 3'UTR luciferase reporter plasmidIFI35 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for IFI35
    Predesigned siRNA for gene silencing in human, mouse, rat IFI35
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: IFI35 (NM_005533)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFI35
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFI35
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for IFI35
    OriGene qSTAR qPCR primer pairs in human, mouse for IFI35
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat IFI35
      QuantiTect SYBR Green Assays in human, mouse, rat IFI35
      QuantiFast Probe-based Assays in human, mouse, rat IFI35

    Additional mRNA sequence: 

    AK025406.1 BC001356.2 U72882.1 

    7 DOTS entries:

    DT.455598  DT.100028280  DT.91753253  DT.92389823  DT.75126564  DT.100778859  DT.120983472 

    Selected AceView cDNA sequences (see all 201):

    CB130670 CB110077 CB138771 BM996594 AW118002 BE276568 AW082544 BQ020479 
    BM717524 BX954767 CA748732 BU629908 BG768141 BC001356 H27116 CA308785 
    BG539757 BU589531 BE893809 BM694278 BG620481 BM917187 BX957004 BU154519 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    IFI35 expression in normal human tissues (normalized intensities)      IFI35 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACGTCCTGGA
    IFI35 Expression
    About this image


    IFI35 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Neurons
             Mature Horizontal Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             Mature Horizontal Cells Inner Nuclear Layer
    IFI35 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    IFI35 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.632258

    UniProtKB/Swiss-Prot: IN35_HUMAN, P80217
    Tissue specificity: In a wide range of cell types, including fibroblasts, macrophages, and epithelial cells

        Pathway & Disease-focused RT2 Profiler PCR Array including IFI35: 
              Interferons & Receptors in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for IFI35
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    QuantiFast Probe-based Assays in human, mouse, rat IFI35
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFI35

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for IFI35 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ifi351 , 5 interferon-induced protein 351, 5 78.32(n)1
    72.03(a)1
      11 (65.07 cM)5
    701101  NM_027320.41  NP_081596.11 
     1014484075 
    chicken
    (Gallus gallus)
    Aves IFI351 interferon-induced protein 35 53.06(n)
    40.44(a)
      420011  XM_418132.4  XP_418132.1 
    lizard
    (Anolis carolinensis)
    Reptilia IFI356
    interferon-induced protein 35
    29(a)
    1 ↔ 1
    6(62507887-62524691)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia ifi351 interferon-induced protein 35 48.96(n)
    38.1(a)
      100495457  XM_002932512.2  XP_002932558.2 
    zebrafish
    (Danio rerio)
    Actinopterygii ifi351 interferon-induced protein 35 49.25(n)
    37.45(a)
      559610  XM_682968.5  XP_688060.4 


    ENSEMBL Gene Tree for IFI35 (if available)
    TreeFam Gene Tree for IFI35 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for IFI35 gene
    NMI2  

    IFI35 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for IFI35 (see all 248)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs728291031,2
    C,F--41156888(+) AGCAAA/TTTTTT 1 -- us2k12Minor allele frequency- T:0.02NA NS 268
    rs1877102531,2
    --41157063(+) GAAGAC/GTTAAT 1 -- us2k10--------
    rs1475073721,2
    --41157085(+) ACAAGC/TGTGTT 1 -- us2k10--------
    rs11082871,2
    C,F,H--41157105(-) AGGAGC/AGCTAT 1 -- us2k113Minor allele frequency- A:0.34NA CSA WA EA 510
    rs1402397931,2
    C--41157123(+) CACTGC/TTAACA 1 -- us2k10--------
    rs1429625111,2
    C--41157126(+) TGTTAA/TCAGTT 1 -- us2k10--------
    rs1131453371,2
    C--41157234(+) CCTCCC/TGGGTT 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1916944941,2
    --41157286(+) ACAGGC/TGCATG 1 -- us2k10--------
    rs6921191,2
    C,F--41157387(-) gaggcG/Agtgaa 1 -- us2k15Minor allele frequency- A:0.40NA WA 10
    rs359750181,2
    C--41157441(+) CAGCC-/TTTTTT 1 -- us2k12Minor allele frequency- T:0.25NA 4

    HapMap Linkage Disequilibrium report for IFI35 (41158742 - 41166476 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for IFI35:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2662750CNV Deletion23128226
    esv2672649CNV Deletion23128226
    esv2672913CNV Deletion23128226
    nsv457742CNV Loss19166990
    nsv483009CNV Gain15286789
    esv33998OTHER Inversion15654335

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing IFI35
    DNA2.0 Custom Variant and Variant Library Synthesis for IFI35

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 600735    OMIM disorders: --

    3 diseases for IFI35:    About MalaCards
    diverticulitis    ovarian cancer    hiv-1


    IFI35 for disorders           About GeneDecksing

    1 Novoseek inferred disease relationship for IFI35 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 1 17197158 (1)

    Genetic Association Database (GAD): IFI35
    Human Genome Epidemiology (HuGE) Navigator: IFI35 (1 document)

    Export disorders for IFI35 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for IFI35 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with IFI35)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. IFP 35 is an interferon-induced leucine zipper protein that undergoes interferon-regulated cellular redistribution. (PubMed id 8288566)1, 2, 9 Bange F.-C....Boettger E.C. (J. Biol. Chem. 1994)
    2. IFP 35 forms complexes with B-ATF, a member of the AP1 family of transcription factors. (PubMed id 8954125)1, 2, 9 Wang X.... Taparowsky E.J. (Biochem. Biophys. Res. Commun. 1996)
    3. Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1. (PubMed id 8938427)1, 2, 9 Smith T.M.... King M.-C. (Genome Res. 1996)
    4. Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility &quot;hot-spot&quot;. (PubMed id 20628624)1, 4 Johnatty S.E.... . (PLoS Genet. 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (Nat. Biotechnol. 2003)
    7. The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling. (PubMed id 17197158)1, 9 Zhang L.... He F. (Cell. Signal. 2007)
    8. Interferon-alpha induces nmi-IFP35 heterodimeric complex formation that is affected by the phosphorylation of IFP35. (PubMed id 10779520)1, 9 Zhou X....Omary M.B. (J. Biol. Chem. 2000)
    9. Intracellular redistribution of interferon-inducible proteins Nmi and IFP 35 in apoptotic cells. (PubMed id 11911807)1, 9 Chen J. and Naumovski L. (amp 2002)
    10. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 3430 HGNC: 5399 AceView: IFI35 Ensembl:ENSG00000068079 euGenes: HUgn3430
    ECgene: IFI35 H-InvDB: IFI35

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IFI35 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for IFI35 gene:
    Search GeneIP for patents involving IFI35

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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