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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

IFI35 Gene

protein-coding   GIFtS: 51
GCID: GC17P041158

interferon-induced protein 35
 Explore 2 diseases affiliated with
IFI35 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for IFI35    

Aliases
for IFI35 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Interferon-Induced Protein 351 2
IFP351 2 3
IFP 352 3
Ifi-353
Interferon-Induced 35 KDa Protein2
Ifi-353

External Ids:    HGNC: 53991   Entrez Gene: 34302   Ensembl: ENSG000000680797   OMIM: 6007355   UniProtKB: P802173   

Export aliases for IFI35 gene to outside databases

Previous GC identifers: GC17M062367 GC17P043320 GC17P041067 GC17P041532 GC17P041533 GC17P038412 GC17P036924


Summaries
for IFI35 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: IN35_HUMAN, P80217
Function: Not yet known

Gene Wiki entry for IFI35


Genomic Views
for IFI35 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the IFI35 gene promoter:
         SRF   HOXA9   HOXA9B   SRF (504 AA)   RREB-1   MyoD   C/EBPalpha   IRF-7A   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: IFI35 promoter sequence
   Search SABiosciences Chromatin IP Primers for IFI35

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat IFI35


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21   Ensembl cytogenetic band:  17q21.31   HGNC cytogenetic band: 17q21

IFI35 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
IFI35 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P041158:  view genomic region     (about GC identifiers)

Start:
 41,158,742 bp from pter      End:
 41,166,476 bp from pter
Size:
 7,735 bases      Orientation:
 plus strand

Proteins
for IFI35 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: IN35_HUMAN, P80217 (See protein sequence)
Recommended Name: Interferon-induced 35 kDa protein  
Size: 286 amino acids; 31546 Da
Subunit: Homodimer. Also interacts with B-ATF
Subcellular location: Nucleus. Note=Nuclear following IFN treatment
Sequence caution: Sequence=AAB61703.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown
origin in the N-terminal part;
Secondary accessions: C9JGX1 Q92984 Q99537 Q9BV98
Alternative splicing: 2 isoforms:  P80217-1   P80217-2   (Variant in position: 128:M->V (in dbSNP:rs588703). Due to a polymorphism at the 3'-splice acceptor site of intron 4)

Explore the universe of human proteins at neXtProt for IFI35: NX_P80217

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P80217

    • IFI35 Protein expression data from MOPED and PaxDb:    About this image 
    IFI35 Protein Expression
    REFSEQ proteins: NP_005524.2  
    ENSEMBL proteins: 
     ENSP00000394579   ENSP00000395590  
    Reactome Protein details: P80217
    Human Recombinant Protein Products for IFI35: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
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    OriGene Purified Protein: IFI35
    OriGene Protein Over-expression Lysate: IFI35
    OriGene Custom Protein Services for IFI35 
    GenScript Custom Purified and Recombinant Proteins Services for IFI35
    Novus Biologicals IFI35 Proteins
    Novus Biologicals IFI35 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for IFI35

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA8288566
    GO:0005829cytosol TAS--

    IFI35 for ontologies           About GeneDecksing



    IFI35 Antibody Products: 
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    Assay Products for IFI35: 
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    Uscn ELISAs and CLIAs for IFI35

    Protein Domains /
    Families
    for IFI35 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IFI35 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR009938 Interferon_induced_35kDa_N
     IPR009909 Nmi/IFP35

    Graphical View of Domain Structure for InterPro Entry P80217

    ProtoNet protein and cluster: P80217

    1 Blocks protein family: IPB009909 Nmi/IFP 35

    UniProtKB/Swiss-Prot: IN35_HUMAN, P80217
    Similarity: Belongs to the NMI family


    Function
    for IFI35 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: IN35_HUMAN, P80217
    Function: Not yet known
    Induction: By interferon gamma

         Genatlas biochemistry entry for IFI35:
    interferon-induced leucine zipper protein IFI35,may be the same as APRF

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18624398
         
    IFI35 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for IFI35 

    miRNA
    Products:            		 OriGene 3'-UTR Clone: IFI35
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IFI35
    1 QIAGEN miScript miRNA Assays for microRNA that regulate IFI35:
    hsa-miR-589
    SwitchGear 3'UTR luciferase reporter plasmid: IFI35 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IFI35 (see all 7)
    OriGene shRNA RFP: IFI35
    OriGene siRNA: IFI35
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IFI35
    Sirion Biotech Custom design and validation of potent shRNA sequences against IFI35 

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of IFI35 
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    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for IFI35 (see all 3)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: IFI35 (NM_005533)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFI35
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFI35 

    Cell Line
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    In Situ Assay
    Products:       
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    Pathways & Interactions
    for IFI35 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Expression of IFN-induced genes
    		Expression of IFN-induced genes1.00
    		Interferon alpha/beta signaling0.61
    2Cytokine Signaling in Immune system
    		Cytokine Signaling in Immune system1.00
    		Interferon Signaling0.61
    3Immune System
    		Immune System1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5        Reactome Pathways for IFI35
        Interferon alpha/beta signaling
    Cytokine Signaling in Immune system
    Expression of IFN-induced genes
    Interferon Signaling
    Immune System



    IFI35 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for IFI35

    5 Interacting proteins for IFI35 (P802171, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CLEC4GQ6UXB41, 3EBI-2115067,EBI-2114729 I2D: score=2 
    BATFQ165203I2D: score=3 
    NMIQ132873I2D: score=3 
    PLEKHO1Q53GL03I2D: score=3 
    MAPK1P284823I2D: score=2 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006955immune response NAS--
    GO:0009615response to virus NAS--
    GO:0019221cytokine-mediated signaling pathway TAS--
    GO:0060337type I interferon-mediated signaling pathway TAS--

    IFI35 for ontologies           About GeneDecksing



    Drugs & Compounds
    for IFI35 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    IFI35 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for IFI35
    1 Novoseek chemical compound relationship for IFI35 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    leucine 58.5 7 8288566 (3), 8938427 (1), 8668343 (1), 8954125 (1)

    Search CenterWatch for drugs/clinical trials and news about IFI35 / IN35 

    Transcripts
    for IFI35 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for IFI35 gene: 
    NM_005533.4  

    Unigene Cluster for IFI35:

    Interferon-induced protein 35
    Hs.632258  [show with all ESTs]
    Unigene Representative Sequence: BU539084
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000415816(uc021txx.1) ENST00000438323 ENST00000246911 ENST00000536969
    ENST00000396722 ENST00000538473 ENST00000546325 ENST00000534876

    miRNA
    Products:             		 OriGene 3'-UTR Clone: IFI35
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat IFI35
    1 QIAGEN miScript miRNA Assays for microRNA that regulate IFI35:
    hsa-miR-589
    SwitchGear 3'UTR luciferase reporter plasmid: IFI35 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for IFI35 (see all 7)
    OriGene shRNA RFP: IFI35
    OriGene siRNA: IFI35
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat IFI35
    Sirion Biotech Custom design and validation of potent shRNA sequences against IFI35 
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for IFI35 (see all 2)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: IFI35 (NM_005533)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for IFI35
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat IFI35 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat IFI35
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat IFI35
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat IFI35

    Additional cDNA sequence: 

    AK025406.1 BC001356.2 U72882.1 

    7 DOTS entries:

    DT.455598  DT.100028280  DT.91753253  DT.92389823  DT.75126564  DT.100778859  DT.120983472 

    24/201 AceView cDNA sequences (see all 201):

    BE276568 CB138771 CA748732 BU629908 CB110077 AW082544 AW118002 BM717524 
    BX954767 BM996594 BQ020479 CB130670 CF453512 BM748764 BG749376 BG181125 
    BQ051574 NM_005533 BU627353 AA195653 BG337860 AK025406 BM694533 BF026268 

    GeneLoc Exon Structure


    Expression
    for IFI35 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    IFI35 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACGTCCTGGA
    IFI35 Expression
    About this image

    IFI35 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeInner Nuclear LayerMature Horizontal CellsHorizontal, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See IFI35 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for IFI35

    SOURCE GeneReport for Unigene cluster: Hs.632258

    UniProtKB/Swiss-Prot: IN35_HUMAN, P80217
    Tissue specificity: In a wide range of cell types, including fibroblasts, macrophages, and epithelial cells

        SABiosciences Expression via Pathway-Focused PCR Array including IFI35: 
              Interferons & Receptors in human mouse rat

    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for IFI35

    Orthologs
    for IFI35 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for IFI35 gene from 4/9 species (see all 9)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Ifi351 , 5 interferon-induced protein 351, 5 78.36(n)1
    72.28(a)1    		   11 (65.07 cM)5
    701101  NM_027320.41  NP_081596.11 
     1014484075 
    chicken
    (Gallus gallus)    		 Aves IFI351 interferon-induced protein 35 52.74(n)
    38.93(a)    		   420011  XM_418132.3  XP_418132.1 
    lizard
    (Anolis carolinensis)    		 Reptilia IFI356
    		 --
    		 40(a)
    		 1 ↔ 1
    		 6(62516768-62524691)
    zebrafish
    (Danio rerio)    		 Actinopterygii ifi351 interferon-induced protein 35 48.12(n)
    36.09(a)    		   559610  XM_682968.4  XP_688060.3 


    ENSEMBL Gene Tree for IFI35 (if available)
    TreeFam Gene Tree for IFI35 (if available) 

    Paralogs
    for IFI35 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for IFI35 gene
    NMI2  

    IFI35 for paralogs           About GeneDecksing



    Genomic Variants
    for IFI35 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/221 NCBI SNPs in IFI35 are shown (see all 221)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs728291031,2
    		C,F--41156888(+) AGCAAA/TTTTTT 1 -- us2k12Minor allele frequency- T:0.02NA NS 268
    rs1877102531,2
    		--41157063(+) GAAGAC/GTTAAT 1 -- us2k10--------
    rs1475073721,2
    		--41157085(+) ACAAGC/TGTGTT 1 -- us2k10--------
    rs11082871,2
    		C,F,H--41157105(-) AGGAGC/AGCTAT 1 -- us2k113Minor allele frequency- A:0.34NA CSA WA EA 510
    rs1402397931,2
    		--41157123(+) CACTGC/TTAACA 1 -- us2k10--------
    rs1429625111,2
    		--41157126(+) TGTTAA/TCAGTT 1 -- us2k10--------
    rs1916944941,2
    		--41157286(+) ACAGGC/TGCATG 1 -- us2k10--------
    rs6921191,2
    		C,F--41157387(-) gaggcG/Agtgaa 1 -- us2k15Minor allele frequency- A:0.40NA WA 10
    rs359750181,2
    		C--41157441(+) CAGCC-/TTTTTT 1 -- us2k12Minor allele frequency- T:0.25NA 4
    rs129411731,2
    		A--41157612(+) tagtcA/Tgaatc 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for IFI35 (41158742 - 41166476 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for IFI35
         1 CNV: 0206

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing IFI35
    DNA2.0 Custom Variant and Variant Library Synthesis for IFI35

    Disorders / Diseases
    for IFI35 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    IFI35 for disorders           About GeneDecksing

    OMIM gene information: 600735    OMIM disorders: --

    2 diseases for IFI35:    About MalaCards
    diverticulitis    ovarian cancer

    1 Novoseek disease relationship for IFI35 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 1 17197158 (1)

    Human Genome Epidemiology (HuGE) Navigator: IFI35 (1 document)

    Export disorders for IFI35 gene to outside databases

    Publications
    for IFI35 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for IFI35 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with IFI35)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. IFP 35 is an interferon-induced leucine zipper protein that undergoes interferon-regulated cellular redistribution. (PubMed id 8288566)1, 2, 9 Bange F.-C....Boettger E.C. (1994)
    2. IFP 35 forms complexes with B-ATF, a member of the AP1 family of transcription factors. (PubMed id 8954125)1, 2, 9 Wang X.... Taparowsky E.J. (1996)
    3. Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1. (PubMed id 8938427)1, 2, 9 Smith T.M.... King M.-C. (1996)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
    6. The PH domain containing protein CKIP-1 binds to IFP35 and Nmi and is involved in cytokine signaling. (PubMed id 17197158)1, 9 Zhang L.... He F. (2007)
    7. Interferon-alpha induces nmi-IFP35 heterodimeric complex formation that is affected by the phosphorylation of IFP35. (PubMed id 10779520)1, 9 Zhou X....Omary M.B. (2000)
    8. Intracellular redistribution of interferon-inducible proteins Nmi and IFP 35 in apoptotic cells. (PubMed id 11911807)1, 9 Chen J. and Naumovski L. (2002)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    External Searches for IFI35 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing IFI35 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 3430 HGNC: 5399 AceView: IFI35 Ensembl:ENSG00000068079 euGenes: HUgn3430
    ECgene: IFI35 H-InvDB: IFI35

    Other Databases showing IFI35 gene

    (According to HUGE)
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    Specialized Databases showing IFI35 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for IFI35 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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    Search GeneIP for patents involving IFI35

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